Aste011011.1
Basic Information
- Insect
- Anopheles stephensi
- Gene Symbol
- -
- Assembly
- GCA_013141755.1
- Location
- CM023248.1:74540472-74543965[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 0.0022 0.12 12.6 3.8 1 20 158 177 158 180 0.93 2 15 3.1e-05 0.0018 18.4 1.9 2 23 245 266 244 266 0.97 3 15 0.19 11 6.5 2.7 1 13 273 285 273 296 0.77 4 15 1.4e-05 0.00083 19.5 3.4 1 23 308 330 308 330 0.97 5 15 0.027 1.6 9.2 2.0 3 23 338 359 336 359 0.96 6 15 4.5 2.6e+02 2.2 0.2 1 23 478 501 478 501 0.90 7 15 2.4e-05 0.0014 18.8 1.1 1 20 525 544 525 547 0.93 8 15 1.5e-05 0.00088 19.4 1.4 1 23 553 576 553 576 0.98 9 15 0.031 1.8 9.0 2.4 1 23 585 608 585 608 0.96 10 15 0.00022 0.013 15.7 3.2 1 23 777 799 777 799 0.95 11 15 0.14 8.1 6.9 3.0 1 23 805 828 805 828 0.94 12 15 0.011 0.64 10.4 0.9 1 23 839 862 839 862 0.97 13 15 1.3e-05 0.00078 19.6 4.2 1 23 972 994 972 994 0.98 14 15 0.00089 0.052 13.8 0.4 1 23 1000 1023 1000 1023 0.96 15 15 0.0024 0.14 12.5 0.8 2 23 1038 1060 1037 1060 0.94
Sequence Information
- Coding Sequence
- ATGGATATGGTACCAGAACAGGAACCAGAACCGGCCGTGGATGATGATCCGGTAGATGTCCCGAATAAAGACCCGGAGTCGTACTGCCGGTTTTGtttctcggagaacgaaattGAACCACTCTTTTCGGCGACTGGAGCCCAGGCAAATACCGAACTGTTGCAACGAATAAACGACTGCTTAGGCATCAAGCTGACCAGGAAGGACTACTGCCCCAGCAGTATCTGCTGGTCGTGTACGCTCACGATGGAGGAGTTTCAGTGTTTTCGCAAACGGTGCTTGAAATTTGACGCGCTCGTACGAAGCCTGCGGCCGGTGGTGAAATCCGAACCCGGCTACAGCGGAACCACCACGCCGACCGAGTTCCTGCAGAAAGGGCATACAGCAGGCGTGAAGCAGCAGGCTGCTGGGAAGGCTGTTCGGCAGGATAAGGGCAAAGGCGCCGCTGCGGGTGTATCGAGCGAGTTGACATTCAAGTGCCAGTACTGTCCACGAAGCTTCAAGCACCGAATGTATCTAGATCAGCATCTTTGGAAGCACCGGGATAGGATTGCGCTGGAAAAGGGATTTTTTCCGGGGCCGAAAAAATCACACCTCAACGGAAACGAAAGCTCGAAAACGACAGCCAAGAGTGTGCCGGCGGCAGAAAcggtaccggtggtcgctggtgctgctgctgctgctgctcctacACCACCACCTGCTACCGGTCCTACAGCCGATCGGCCGATTAGCTGTGAGTATTGTCCACGGAAATTCACCCGCAAGATGTACTACATGCAACATCTCCGTCGGCACAAGCCCGACGAACGGTTGTTTCGATGCCGACACTGTCCGCGCAGCTTTACATCGCACCTGAGACGGGTTGGGCACGAGCGAAAGATACATCTAACCAACCCGAAGCCCGAGGAAAAGGACACCTTCTCCTGTCCCAAGTGCTCGCGCGTGTTCAAGCACCGCTCATCGTTACGCATGCATCTGCTGAATCATGACGGCCAGCTGCCGTACGGTTGCGACATATGCAACTGTCGCTTCTACAGCGTGAGCTACCTGGCGCTGCACAAAAAGCGCTACCACGGACCTAACGCTGCCCGCGGTGTGGCGAACGGCACCTCCATCCCCTGCCTGTACTGTTCGCGCTGGTTTTTGCGCGAATGTGACCGTTCAAGCCACATCAAACAGATGCATGCGGATATGCACGCAAGCAAAGAATCGGCCGCCGGGTTTAACCAGCTGCTCGAAGACTGCCCCCCGGCGGACAGTGACGGGCTGACCGATCCGGGCATACTGCCACCAAACGTGCGCGAACCGATGATGGTGATTAAGGAGGAGGAACCGGATGCGAATGACCCGGCACCGACAAGCGCAGCCGCCGCCGACGCAGCCACCGCCACCGACTCCGGCGTGGCTACTGATCCTGGTGCATTTCCGTTCTACTGTTACTCATGCGCCATGCCCTTCGACACGGAGGACATGTACTCGGAGCACTTGGACGACCAGCACCCGTTTGGGGGCGAACAGCTGATGGATCAGCTGGACGCTTCCTCAGCGATGGAACAGGACGCGAAGCTGTTCAAGTGTCCCTTTTGTCCGAAAACGTTCACGCGCAAGTGGAGCATGACCCAGCACATTCCGTCGCACATGGCCCGGAAGGGGTATCAGTGCGAATACTGTCCAGCCATCTTCACGCGCAACGAGTACTTGCGCACACATCGGCAGCGCAAACATCCGACACTGCCGGAAACGGGTTCGTTTAAATGTAGCTACTGTCCGCGGATGTTCCACATGGCACGGTACAAGAAGGTGCACGAGCGGATCGCACACATAAAGAAGGGCGACACGCTGCCGGAAGGGGACGATACGGAAAGTGAGCTGGCCGCGATTAACAGCAGCACGGTGGACAAGATGGacgagagcagcagcagcatggcgGCGCACGATCTACACTCCCGTGCGTCGGACAGCTACGATCAAACGTCCAACGACGCGCACAGTGTGCTGTCCATGCAGCACTACGCGGACTTGGAGGCGTCGGTGCGGCTCGCCGTGGTGCTGGAACGATTGCCGGCAAAAATACTGGACGAATATCGATGGCAGCTGGAGCTGTACGCGACTATGTCGCCGGAAGATAGCCAGCTGGAGCTGATGGAAATGCCCGAGGACCTGCCGGATGTGACATTCGATGATGCAGACTTTGACGATTACGGAGATGACGATGGCATGGATGAAGGGGGAAGCGGTGCGGGCACTCCGCTGACCCATGAAGAGTCTAACGATTCCGGAAAGCAGATGTTAAAACGCAAGCGCAGCAAGTTCGGCATCACCCTCCATCCGTGTCCGCACTgtacgaaaatgtttaaatcTCGCACGGCGCTGCGAATGCACGCGCTGTACCACAGTGGCGATTTGCCGCACCGGTGTGACGAGTGTGGCGTTCAGTTTATGCGTTACAATCAGCTGGATTACCACAAGACCAAATATCATGGTGCCAACAGTGCGACAATGGCCGCCCGCTACAGCTGCGACTACTGTCCGCGCATTTTCCTGCGCAAACAGGATCGTACCACGCACCAGATGATGGTGCACGCGCGCGATCAGGCGGAATCGATCGACGCATCGCCCGCGCTCGCGATGATGAAGAAATCGAAACGAAAGGACTACGTGTGCCGGGTGTGCGACGCGGACTTTGAGAAGTATCGGCGGTGTGTGCGGCACATCGCCTTACATCACTTGGGGGCGGACGGTGAGCCGGAATGTAAACCGATCAAGCTGTGCCACTGCAGCATCTGTACGGGCATCTACAAGAAGCGCGAAGATTGGCACGAGCATCTGAGCGACCATCCGAGCGTGAGGCCGCATCACTGCGAACAGTGCATTCGGAGGCGAAGGAAAGCTTCCAGCCGGAAGCAGGTGCACCGCTGCACGCACTGTCCGAAGGCGTTCGAACACAAGCCCAACCTGGCGTCGCACTTGCGCATACACATGCAGCAGCTACGGTTTCCCTGCAGCGAGTGTGGCGTCATGTACGATCGGTATCGCGATCTGCTGACGCACCAGAGCCGTTATCACTCGGAAAATCCATCCGATGCGGTTGGCCGTGAACCGCTGCAAAGGTGCAACTTTTGTCCGAGAGTGTTCACGCGCCTGCGTGACGTCAAGTACCATCAGGAGCAGGTGCATGCCGATCGGATAGTGCCTCCGACCACCGTGGAGGATAACAATGGGCCGGAAGCACTGGGGGACGAAGGGCTGCTAACGTTCGGCTTCGGCCCGGAAATGTTTCCTGAGACTAGCCTGCAGGAAGAGCCGCCCATCGAAGGGGCTGgcgatggtggcggtggcggtggcgtcGGCAACGTTGGCATCGGCGAACTGCCAATAAAACCTGACCCAGATCAGCAAGACCTCACGACATCACAGTAA
- Protein Sequence
- MDMVPEQEPEPAVDDDPVDVPNKDPESYCRFCFSENEIEPLFSATGAQANTELLQRINDCLGIKLTRKDYCPSSICWSCTLTMEEFQCFRKRCLKFDALVRSLRPVVKSEPGYSGTTTPTEFLQKGHTAGVKQQAAGKAVRQDKGKGAAAGVSSELTFKCQYCPRSFKHRMYLDQHLWKHRDRIALEKGFFPGPKKSHLNGNESSKTTAKSVPAAETVPVVAGAAAAAAPTPPPATGPTADRPISCEYCPRKFTRKMYYMQHLRRHKPDERLFRCRHCPRSFTSHLRRVGHERKIHLTNPKPEEKDTFSCPKCSRVFKHRSSLRMHLLNHDGQLPYGCDICNCRFYSVSYLALHKKRYHGPNAARGVANGTSIPCLYCSRWFLRECDRSSHIKQMHADMHASKESAAGFNQLLEDCPPADSDGLTDPGILPPNVREPMMVIKEEEPDANDPAPTSAAAADAATATDSGVATDPGAFPFYCYSCAMPFDTEDMYSEHLDDQHPFGGEQLMDQLDASSAMEQDAKLFKCPFCPKTFTRKWSMTQHIPSHMARKGYQCEYCPAIFTRNEYLRTHRQRKHPTLPETGSFKCSYCPRMFHMARYKKVHERIAHIKKGDTLPEGDDTESELAAINSSTVDKMDESSSSMAAHDLHSRASDSYDQTSNDAHSVLSMQHYADLEASVRLAVVLERLPAKILDEYRWQLELYATMSPEDSQLELMEMPEDLPDVTFDDADFDDYGDDDGMDEGGSGAGTPLTHEESNDSGKQMLKRKRSKFGITLHPCPHCTKMFKSRTALRMHALYHSGDLPHRCDECGVQFMRYNQLDYHKTKYHGANSATMAARYSCDYCPRIFLRKQDRTTHQMMVHARDQAESIDASPALAMMKKSKRKDYVCRVCDADFEKYRRCVRHIALHHLGADGEPECKPIKLCHCSICTGIYKKREDWHEHLSDHPSVRPHHCEQCIRRRRKASSRKQVHRCTHCPKAFEHKPNLASHLRIHMQQLRFPCSECGVMYDRYRDLLTHQSRYHSENPSDAVGREPLQRCNFCPRVFTRLRDVKYHQEQVHADRIVPPTTVEDNNGPEALGDEGLLTFGFGPEMFPETSLQEEPPIEGAGDGGGGGGVGNVGIGELPIKPDPDQQDLTTSQ
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00103853;
- 90% Identity
- -
- 80% Identity
- -