Basic Information

Insect: Anopheles stephensi
Gene Symbol: prg
Assembly: GCA_013141755.1
Location: CM023249.1:75881478-75883461[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.84 48 4.5 1.0 1 20 232 251 232 255 0.74

2 10 1.2 70 4.0 0.2 5 23 265 284 262 284 0.91

3 10 4e-05 0.0023 18.1 1.4 1 23 290 312 290 312 0.96

4 10 1.3e-08 7.4e-07 29.1 2.8 1 23 318 340 318 340 0.98

5 10 0.00016 0.0095 16.1 0.8 1 23 346 368 346 368 0.95

6 10 0.096 5.5 7.4 1.0 1 21 375 395 375 396 0.93

7 10 3.4e-05 0.002 18.3 1.4 1 23 477 499 477 499 0.98

8 10 0.00033 0.019 15.2 0.7 1 23 507 529 507 529 0.99

9 10 3.8e-07 2.2e-05 24.4 3.3 1 23 535 557 535 557 0.97

10 10 0.00025 0.014 15.6 3.0 1 23 563 585 563 585 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.84	48	4.5	1.0	1	20	232	251	232	255	0.74
2	10	1.2	70	4.0	0.2	5	23	265	284	262	284	0.91
3	10	4e-05	0.0023	18.1	1.4	1	23	290	312	290	312	0.96
4	10	1.3e-08	7.4e-07	29.1	2.8	1	23	318	340	318	340	0.98
5	10	0.00016	0.0095	16.1	0.8	1	23	346	368	346	368	0.95
6	10	0.096	5.5	7.4	1.0	1	21	375	395	375	396	0.93
7	10	3.4e-05	0.002	18.3	1.4	1	23	477	499	477	499	0.98
8	10	0.00033	0.019	15.2	0.7	1	23	507	529	507	529	0.99
9	10	3.8e-07	2.2e-05	24.4	3.3	1	23	535	557	535	557	0.97
10	10	0.00025	0.014	15.6	3.0	1	23	563	585	563	585	0.97

Sequence Information

Coding Sequence: ATGAACATTGGGAATGGCCCCATACCGGCGGTGGAGCGACAACTTTGTCGGCTTTGTTTGGGAAAGGAAGGCGAATTGGTAGACATATTCGGTGTACAGCAGGCAACGAGCCTGGGTGAACCGTTGCCGGTGCGGATACAGGGCTGCCTGCAGCTGGATATCACACAACACGACAGTCTACCTAAATGGATATGCAAACGGTGTTTGGAGAAGATCGATGACTTTACCAGCTTCCGGGAACGATGCAAGCTGAACGAGCGGAAGCTACTGCTTGGCGGTGAGCATGGTGGTCCGGGGGAGAGCTTTCACGCTGCGGAGATGCACTCGGATGACGGTagcgatgatgatgcggatgacgatgaggaagaaatggaaatgatTGTCATCGATCCCTCGCAAGACTATGAAAGCTCGAACGACAGTCTTCCGAACGAGGAAGCGTACGATGAAAAAAGCGCGACAAATGCGCTTCTTCCGATACCTCCGCTTACCATTAGCCGACAGCTGAACGCGACCGCCGAAGAGGAAGACGCGGATGGTTCCGATGCCGAGGAAggcgaggaggaggaagaagaggaagaggaaggaGAAACAAAATGTGATACGGTGCTGGCGGGCGAGCAGCGCAATGGATTGCCGGATCCCATTGGCAGTGGCACCACCACACCGAGCAAGGCACAGAAAACGGTCGTCCACACGTGCAAGTACTGCGATGTGGCGTTTGGGGCCGCATCCGCCTGCCAGCTGCACGAAATGCAAGACCACGATCTGCTGGCACCGTACGGTTGCATCTACTGCGAGTACAAAACCTCCATCCGGACGTATCTGATCACGCACATCCGCGATTCGCACAGTGTCGCCCGGCCGTACATCTGTGTGCAGTGCAACAAGGGATTCATGCGCCGGTCCGATCTCAAGAAGCACACGTTCGTGCACACCGGCATACGGCCGTACGCGTGCGACCAGTGCAGCAAAAGTTTCTCGCGCAACACGAATCTCAAGAAGCATATGCGCACCCATCTCGGGTTAAAGCCGCACGCCTGCACGGTTTGTGCTCGATCGTTCGCGAACAAGGCGGACTTGGTGCGGCACCGGAGCTATCACCAGGAGCTGGTACCGCAACATTCGTGCGTACGCTGTGGAACGCTGTACACGCAAAAGGATAAGCTGTACGAGCACGAGCGGTACTGTATGGGACAGACGGCGTTCAGTTTCGGGCTGGGAGTACCACCGCTGGTAGAGTCGGTAAAGCAGGAGCTACCGTTTCAGGGTAGTTTGGGTGGTTCGATTCCACCGCCGGAAGGTGTACCGGCGATGGAACCGAATCCTGCCCAACCCCGAATCGTTGACGACCCGCCAACCTACAGTCTGGATCCTGCTTTACCACCCAACCCGAACATGCCACAGACTCCACCGTCGAGCAAAATCTACAGCTGCACGAAATGTCCCAAACGGTTCCTGAGTAAAGCGAGCCTACGGGCACACCAGAGCACCCATCCGGCGGATGAAAAGCGCATCTACGAATGTCCCCAGTGTAAGAGCTCGTTCGACGGTAAGCGTGAGTACGAACAGCACCTTCAAACTCACCCCGAGCTGAAACCGTTCGCGTGTCCGACCTGTGGCAAGCGGTTCTCGCGCCGCGACAAACTTCACCGCCACGAGCGTACCCATCAGCAGGATCGTAACTTTTGCTGCCCGCACTGTTCGGCCAACTTTGTGCGGAAGGATGCGTTCGAGTCGCATCTGAAGATTCACTGCAATCCAACCGGGGATGGTTCGTTGCTCAGCTCGCTGGGACACGTACCGGGCGTACCGGAGCTGATGGTACCGATGCAACAACATTCCCTGCTGTATTCCATGGTGCGGGAAGATGGAACGATGGCCATCGATCCGTCGATGCGTATGTGA
Protein Sequence: MNIGNGPIPAVERQLCRLCLGKEGELVDIFGVQQATSLGEPLPVRIQGCLQLDITQHDSLPKWICKRCLEKIDDFTSFRERCKLNERKLLLGGEHGGPGESFHAAEMHSDDGSDDDADDDEEEMEMIVIDPSQDYESSNDSLPNEEAYDEKSATNALLPIPPLTISRQLNATAEEEDADGSDAEEGEEEEEEEEEGETKCDTVLAGEQRNGLPDPIGSGTTTPSKAQKTVVHTCKYCDVAFGAASACQLHEMQDHDLLAPYGCIYCEYKTSIRTYLITHIRDSHSVARPYICVQCNKGFMRRSDLKKHTFVHTGIRPYACDQCSKSFSRNTNLKKHMRTHLGLKPHACTVCARSFANKADLVRHRSYHQELVPQHSCVRCGTLYTQKDKLYEHERYCMGQTAFSFGLGVPPLVESVKQELPFQGSLGGSIPPPEGVPAMEPNPAQPRIVDDPPTYSLDPALPPNPNMPQTPPSSKIYSCTKCPKRFLSKASLRAHQSTHPADEKRIYECPQCKSSFDGKREYEQHLQTHPELKPFACPTCGKRFSRRDKLHRHERTHQQDRNFCCPHCSANFVRKDAFESHLKIHCNPTGDGSLLSSLGHVPGVPELMVPMQQHSLLYSMVREDGTMAIDPSMRM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -