Basic Information

Insect: Anopheles stephensi
Gene Symbol: -
Assembly: GCA_013141755.1
Location: CM023250.1:6849559-6865728[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 1.5 87 3.7 0.0 2 23 4 25 3 25 0.96

2 14 0.0031 0.18 12.1 1.3 1 23 1604 1627 1604 1627 0.97

3 14 0.01 0.6 10.5 1.4 1 23 1754 1776 1754 1776 0.97

4 14 0.0011 0.064 13.5 2.3 2 23 1779 1800 1778 1800 0.95

5 14 0.00076 0.044 14.0 1.8 1 23 1806 1828 1806 1828 0.98

6 14 4e-05 0.0023 18.1 3.5 2 23 1835 1857 1834 1857 0.96

7 14 0.00063 0.036 14.3 0.6 1 23 1867 1889 1867 1889 0.98

8 14 0.00016 0.0094 16.1 2.8 2 23 1895 1917 1894 1917 0.96

9 14 0.0094 0.54 10.6 0.6 3 23 1931 1950 1930 1950 0.97

10 14 6.4e-05 0.0037 17.4 0.9 1 20 1957 1976 1957 1979 0.92

11 14 0.001 0.06 13.6 0.2 1 23 1987 2009 1987 2009 0.97

12 14 0.0001 0.0058 16.8 3.1 1 23 2015 2037 2015 2037 0.98

13 14 0.00055 0.031 14.5 5.8 1 23 2043 2065 2043 2065 0.98

14 14 0.0035 0.2 12.0 3.5 1 23 2071 2093 2071 2094 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	1.5	87	3.7	0.0	2	23	4	25	3	25	0.96
2	14	0.0031	0.18	12.1	1.3	1	23	1604	1627	1604	1627	0.97
3	14	0.01	0.6	10.5	1.4	1	23	1754	1776	1754	1776	0.97
4	14	0.0011	0.064	13.5	2.3	2	23	1779	1800	1778	1800	0.95
5	14	0.00076	0.044	14.0	1.8	1	23	1806	1828	1806	1828	0.98
6	14	4e-05	0.0023	18.1	3.5	2	23	1835	1857	1834	1857	0.96
7	14	0.00063	0.036	14.3	0.6	1	23	1867	1889	1867	1889	0.98
8	14	0.00016	0.0094	16.1	2.8	2	23	1895	1917	1894	1917	0.96
9	14	0.0094	0.54	10.6	0.6	3	23	1931	1950	1930	1950	0.97
10	14	6.4e-05	0.0037	17.4	0.9	1	20	1957	1976	1957	1979	0.92
11	14	0.001	0.06	13.6	0.2	1	23	1987	2009	1987	2009	0.97
12	14	0.0001	0.0058	16.8	3.1	1	23	2015	2037	2015	2037	0.98
13	14	0.00055	0.031	14.5	5.8	1	23	2043	2065	2043	2065	0.98
14	14	0.0035	0.2	12.0	3.5	1	23	2071	2093	2071	2094	0.95

Sequence Information

Coding Sequence: ATGGCGATCGAATGTCCCGTCTGCACGCTGTTCCTTCGGTCGGGCATGACCCTGGCCGAGCATTTAGACACGCATCCTAAAGAAAATGTGATAAAGGCGTTGGTCAACATCGTAAAGCACGACGCTTTAGCCTACTATCCTAACACGCTGGAGGAGGCGGGCGGGGATGAGGTCGTACCGGTGGAAGGCAGCACGTCCACCATCAGTAcggccaccaccagcagcacactCACGCTCCGGACAAGCGAAAGGACAACCTCGCTCGGTATCTACGACGCGCAACCGGTGTACGTGGACAACGCGATACTGGCATCACCGGGCAATGCGGTGCAAGCGTCGGTGAGTCAACCGTCGCAGTTTGCGGTGGTAAAAGCGATCGATGCGCACGGTATTCCCAGCTTTCACCTTAACAACGTAACGCTGATCAAGCGCGAACTCGTGCAGCCCGTCGCGGCTGTGTCAGGCTTGTCCGCGCTAACGGCAGGAGCTGCGTCGCATACCACAGCGTCCGGCGCTACTATCGGGACGGTGCAAGGTGAGCTGTCTACCATCGGTCCGGCGTCGGACGATTACGTCGAACCACCGGGTGGCAGTGAAGCAGGTTCGTCTCGTGCGATAGGAACCGCTGCTGTGCCGTCCACCACCGTCTATCCCCGCTACACAAACGAGCTTTATTCCGGGCCACCGCCACCATACAGTCGGGCCATATCCTCTACGATTGCTACCAATACGCAGATAACAccagcacagcagcaacaacccaCGGTCCAGCTGAATGTGACACCGAAACCAACCGTCGGTGGTGTCGGTGTCGTCGGCCAACCGTTGCAACTATTTCCCAAGCTCCATTCGGAAACATCCAATTCCGCTTTTAAACAGTATCCAACGGTCCAACAGGCCGTGCCCGACCGTACCGTCGACGAGACGGCAGTAACGGTAGCAGCAAACCCACCACTGTCCGCCTCAACACCGAAACCCGTCTACAGTGCGCCTGTGGCAACAACAATTGCTTCTAAAATTGTGGCAACAGCGGCCATCGCcgctagcagcagcatcagttcCTCCACCACTTTGTCCGAGCAACAATCAACCAGCGTTCCAGTAACATTCGTGACGACAACTACAGCCACCACGCCCAAGACCAGCGTTTCGACCCCATCGAAGGCGAACGTTGTGAAGGTAATCAGCAACGTCAAGGTGCAAAGTAAGCTTAAGGACATACAGGAAATCATATTGCAGCTGAATGCCGGTCAGATGTCGATCGTTGGCGACAAGACGACGCTGATTCCACCCACCACCGAAAGGCGACCATCCGCGTTTGCGGCTAGCGGTGGATCCGGCCGGTCCTTGCTAGCGATAACGCCAACCAAAGCGGAACCCACCACGACGGAGCAGCCACAGCCGACCAATGCACCCAGCCACATGGAAGTGAACCAGGACGGTATGGAGGAGATAGAGACTTGTGATTATGATCACGAGATGGATTATAGTGATGGTTGGCAGGACGATGATAACTATACCGGTGAAGACGTACCCGAACAGTGGGTGGATGCACCGGAGGTCAAGCGTTTTGCTGGCGATGGTGAAGCGCCGAATGAAGTACTACCGGCAGCAGAGAGGACGACAGCATCAACGGCTGCAACTACCGAATGTTCCAGTACCAACGGCAACAGTACCAGCAGCGCGATGGTCACCAGCGTTATCCGGAAGACTCCGCAGCCAGTACCGTGCGCTCCATCGCCCATACAGCAGGAACCGAAATCGCAAATCAAACGTTTAGTATTTCGGGTGGCAGGTAACTGCACACCAACCACCGTAACGATTGCGCCCGCCGGtgcgtcatcatcatcctcaacGCAAATAGTTCGCGCCTGGCAAGGCATTAAGCTGGAATGCACACCGGAAGGGTCGACCGGTGCGCCCAGCAATGCTGCACCGACCGAAGAGGAGCTGGGAAAGCCGGCCAGCTGTGCGTCAGCCGCGTTAGCTGGTCGTGATTATGCAgcgaagcagaagcagcaacgcttccggccaccaaaaaaGCTAGCGATCAAACCTAAAAGGTCCGCTGCAGAGGGGGGCACCTTTCCCGGCACCCAATGCCCGACGGTAGATGGTGGGGATGGCGCTCAGGATGAGACGGCGGTGGGTTCGACGTCTTCGACAGCGGCGCTGTCCACCTTGGCGGAGGTGGTATGCACGAACGcagcccaacagcagcaagcgaACGCGATGGAACCATTTTCCTCCACCTCGTTCAACGGCATAACGGCCGTTATTCAAAAGACTGACATTAACGGTGGACCCGCTCACGCTTACCCAGACCGTGAGCTGATTAGCCAGCAACCGTTACTGATGACTCCCATCAAGCAAGAATTTGCCCGCACCACAGATAGCGCTGCGCCGGCAGACGTTACGCCCAAGCCGTTAAACAAGCCGAACGTGGTGCTCGCTGGCCGTACGTCCTATACGTTCGTAACGCCCAacactggtgctgctgctgctgctactacttccAACGCCAACGCCGGCCGAAAGGTGTCGCATCCTACGGCCGAGATCGATGTCGGGGCGTACAACATTTCGTACGTAAGCGAAACGGGCGAAACGATCTACCATCCACTGCCTAAGAAAGCGAACGGCACGATCGGTACGGCCGAGTTTGCCAGTCGGAAACAGCCCACGAACGAGCATAAACTAACGCCCGCCGGAAGAAGTCCCGAGGGTGGTGTGATCCCGCAACACGCCGACCACTTCCGGGCGATGGAGAAGGAGCAGGCGGAGCTTAAAGAGGAGGATGGAAACCATGGTACAGCGTTACAGGGTgaaggtggtgatgatgatgcgctgGAGGACGATGATGCGAGAGGcttggatgatgatgagatgaTAGAGACGGAAGATGATCTAAAGGAAGCATGCGATGAAATAGTGCATGCAGCAGCGGACGGCGAGCAAGAGGAACGGTTGGACagcgaggaggacgaggaggaggaggaggaggagtatGATGATGTGTTCGAGGTAGAGCCCGTACGCCACCAGCAAGCTCCTCATCACCAAACACAGTCACCGTCCGGTGAGCAACCGTCCCGTCGCCGGTTGCTAATGGTGCTGACGAGGATGAATCAAGTACCGCGGGATGCTACCGATCGAAATGCAGCCGTAAGCGTAACGGAAGTAGCGGTCGAACCGATCGGTGCTGAGCTGGACGTAAAAGATCATTTGGACCGGCCGGAACAGAAAGCCGCCACCATCGACAACGAAACAAACTCCGCAGAAGCGCAAATGCACCATGAGCCGGAAACGCCGCATACTACCGGTTTGCCGGCAAGCTTGGTAATGAAACGTTTTCATTCCGGTACGATCACGACGGATGACGAGAAGGATATGCTGGAAGCTGGACCTTCCACGCGCAACATTGTGCACATTGGCGTACCATCACGGCCTAAGATTCGTGTCACGAACGCCGAACCGTTCCAGACAAACGGACGTTCCAGTTCGGCCAGTAGAAAATCGGAGCCCGATGAGCGTAAAAAGGCGGACCCGTTGAAAAGAGCGTGTGAGAAAGATTTTCTCGAACCGGGCACAtcgtcctcatcgtcatcgtcatcctcCTCGTGCCATCGGTTTGAAACCGGTTCGGTCTATACGACCGACCACACCGAGGATAGTAGTGGCGGGTGTTTGAGACATTGCTTCAACAGTCCGGCCACCGCGGCCGTCGATGAGCCGATGCCGGTGTCCTCGTTGCAGGAACCGCCCGTCGGACTAAAGCTGGAAAAAACTGAACCATCGTACGCTGACGAGCACGATGAGCAGGACACTACCACCTCCTCGTTTCTGGACCTTAGCACGGTACCGAAAACGAGCCTCGATGGGCTGAGCACCAACGACACGgccagcaacaccagcagcagcagcaccagcagcaacagcaatcaCAGTGCAGGGCTGGGCAAAGACGGTGGGGAAGGTAGTGGGACGAGCCACGGCGGAACGCGGTCCCTACTGCCCTCGGGTTCATCGATGGCGTCCACCAGCATGGAACGTGCGCCATCGACCGAGAGTCTCAACATACGCACCGACGAGAAGATGCCGGCAAAGGGTGAAATTTCCGAACAGGAAAGCAACGGCGATATGGACGTTACGTCGTGGAACCATCGGATGTACGCGGTCGGGGAGAATGTGCCTATCTATCCGAGCTCGTACGATTTGTCGACCGCACAGGAGTGTTGGAATCTGAGCAGCCGCAACCAGGGCATCTTTGCCGTAACGGATCATTTttatcatcagcagcagcagcagcagcaacagcagcagcagcagcagcagcaacagcatggTGGCGGTAACAATCCACACGGAACGACGGTCAGCAACCAATACATGACTTCGCGCGTTGCCTTTCAATTTTCGTCCTCGTCACATCAACAACTGCAGCAGCATGGAGCGGACCATCTGCCGTTCGGTGGTGGGATGATGGCGGGCAAGATGGAACCGCCCCAGGACGATGAGGACAGTGACGAGGTGGACGAGGCAGTGGAGGCACGCCGCCTGAAGAACGCTATCCCAAAAATGCCGTTCGCCGATATGATGGTCGCACGCCTGCACGAACCACCCGGTGCGTACGATGAGGTGGTGAGCAGCACGCACCACCTCCCGCAGCAATCGTGCGAAACGAAGTACGATGATCCGGTCGGTACGACGTCGTACTTCGGTGTAAGTTCCGCCCTGCCGCTAATGCCGACGGATGACTCCGGTCTGTCCAGCAGGCCCAAACCTTCCGGGAGCGGTGTGGCCCGTACCTTCCGCTGTACGCTCTGCCCGAAAGTGTTTGACACGATTAAGCAGCGTCGGTTGCATCAGCAGCGGGAGCATGCGAGTGAGCTGTTGTCGCTGGCAGCATCCCATCCAAATCAGGAGCAACTGCCGCTGGGTGAGGATGGCAGTGAGGCGGGcaggcagcaacagcagcagcagcagcagcagatgttCAAGAAGCAACCGGTACCGGTTGTAATGAACTACGATTGGATGAAGCAGGAAATTCAGCGTAAAAGTGAGGCGATGTTAAAGAGTAGTCGCCTGCTGATGCCCGGCAGCAGCCACAgctccggtggtggtggcccggGGCCGAGCACCGGCGAGAAGATGCAGCAACCGGAGCAGCTGGTGGTAGCCCAGGTGCAGGTAGCCACCGGCGATGGGAtgctgccagcagcagcgtgtacGATCGCCGCCGCCCGTAACCGCACCTACGTGTGCAGCACCTGCAACCAGAAGTTCGATCGGTTCAATCTGTTCAACGAGCATTTGCTCGAGCATCCGGTGGAGTGTTTCGCCTGCGGGCGGCACTTCAAGCAGTGGCGCAACTTCTCGCTACACATCAAGCGGCATCTCGGCATCAAGGAGCATCAGTGCCGCAGCTGTGGCAAGCAGTTCGTGATCAAGCAGAAGCTGATCGAGCATATGCGGGTGCACACCGGGCACGCGCCGATCAAGTGCAAGCTGTGCAATCGTACATTCAAACGCTTCTCCAACCTGGCGCAGCATCGCAAACGGTACCATCTGAACCGGACGGTCGCGAAGGAGGACTACGTGTGTTCGCTGTGCGGCGAGGTGTTTCACACCCAGGCAAAGATGGAATGGCACAAGGAAACGCACGAGAAGAAGCCCAAATCGTGCCCGTACTGTCGGGAGAAGTTTATCCACCGGAACAGCTTGACGCGCCACATACGCCTCTCGCACACGGATAAGTACGCCAAGCTGGAGAACAAAACGGAACCGTGCAGCATCTGTCAGCAGCCGTACACGAAGACCAGCATGCGCCGGCACATGGAAACGCACACGAAGGAGCGGATGGCGTACGCGTGCGGCATCTGCAACAAGCGCTTCACCACGAACTGGAACCTGAAGCAGCACAAATGGACGCACGCCAATCCGACGATGAAACCGTTCCAGTGCACGTACTGTCCGAGTGCGTTCGTGCGCGAGTCGGACTTTGTGACGCACGTCAATGCGCACCGATCGATACGGCCGTACACGTGCAATCACTGCGGCAGTCAGTTCATCCGGAAGTACAACTGGATACGGCACACGCGGGAGCACGAGCTGGATAAGGGCCATCGGTGCGATGTGTGCGGTCGGCAGTTTCACCGGAAGTACTACCTGACGGAGCACAAGCGTATCCACACCGGGGAGCGACCGTTCGCGTGCAACATCTGCGGCAAAACGTCCGCCACGAAGACGAACCACAACAAGCACGTCCGGATTCATCATGCCCGCGATCCGCTCACGGCGGAAGGTTAG
Protein Sequence: MAIECPVCTLFLRSGMTLAEHLDTHPKENVIKALVNIVKHDALAYYPNTLEEAGGDEVVPVEGSTSTISTATTSSTLTLRTSERTTSLGIYDAQPVYVDNAILASPGNAVQASVSQPSQFAVVKAIDAHGIPSFHLNNVTLIKRELVQPVAAVSGLSALTAGAASHTTASGATIGTVQGELSTIGPASDDYVEPPGGSEAGSSRAIGTAAVPSTTVYPRYTNELYSGPPPPYSRAISSTIATNTQITPAQQQQPTVQLNVTPKPTVGGVGVVGQPLQLFPKLHSETSNSAFKQYPTVQQAVPDRTVDETAVTVAANPPLSASTPKPVYSAPVATTIASKIVATAAIAASSSISSSTTLSEQQSTSVPVTFVTTTTATTPKTSVSTPSKANVVKVISNVKVQSKLKDIQEIILQLNAGQMSIVGDKTTLIPPTTERRPSAFAASGGSGRSLLAITPTKAEPTTTEQPQPTNAPSHMEVNQDGMEEIETCDYDHEMDYSDGWQDDDNYTGEDVPEQWVDAPEVKRFAGDGEAPNEVLPAAERTTASTAATTECSSTNGNSTSSAMVTSVIRKTPQPVPCAPSPIQQEPKSQIKRLVFRVAGNCTPTTVTIAPAGASSSSSTQIVRAWQGIKLECTPEGSTGAPSNAAPTEEELGKPASCASAALAGRDYAAKQKQQRFRPPKKLAIKPKRSAAEGGTFPGTQCPTVDGGDGAQDETAVGSTSSTAALSTLAEVVCTNAAQQQQANAMEPFSSTSFNGITAVIQKTDINGGPAHAYPDRELISQQPLLMTPIKQEFARTTDSAAPADVTPKPLNKPNVVLAGRTSYTFVTPNTGAAAAATTSNANAGRKVSHPTAEIDVGAYNISYVSETGETIYHPLPKKANGTIGTAEFASRKQPTNEHKLTPAGRSPEGGVIPQHADHFRAMEKEQAELKEEDGNHGTALQGEGGDDDALEDDDARGLDDDEMIETEDDLKEACDEIVHAAADGEQEERLDSEEDEEEEEEEYDDVFEVEPVRHQQAPHHQTQSPSGEQPSRRRLLMVLTRMNQVPRDATDRNAAVSVTEVAVEPIGAELDVKDHLDRPEQKAATIDNETNSAEAQMHHEPETPHTTGLPASLVMKRFHSGTITTDDEKDMLEAGPSTRNIVHIGVPSRPKIRVTNAEPFQTNGRSSSASRKSEPDERKKADPLKRACEKDFLEPGTSSSSSSSSSSCHRFETGSVYTTDHTEDSSGGCLRHCFNSPATAAVDEPMPVSSLQEPPVGLKLEKTEPSYADEHDEQDTTTSSFLDLSTVPKTSLDGLSTNDTASNTSSSSTSSNSNHSAGLGKDGGEGSGTSHGGTRSLLPSGSSMASTSMERAPSTESLNIRTDEKMPAKGEISEQESNGDMDVTSWNHRMYAVGENVPIYPSSYDLSTAQECWNLSSRNQGIFAVTDHFYHQQQQQQQQQQQQQQQQHGGGNNPHGTTVSNQYMTSRVAFQFSSSSHQQLQQHGADHLPFGGGMMAGKMEPPQDDEDSDEVDEAVEARRLKNAIPKMPFADMMVARLHEPPGAYDEVVSSTHHLPQQSCETKYDDPVGTTSYFGVSSALPLMPTDDSGLSSRPKPSGSGVARTFRCTLCPKVFDTIKQRRLHQQREHASELLSLAASHPNQEQLPLGEDGSEAGRQQQQQQQQQMFKKQPVPVVMNYDWMKQEIQRKSEAMLKSSRLLMPGSSHSSGGGGPGPSTGEKMQQPEQLVVAQVQVATGDGMLPAAACTIAAARNRTYVCSTCNQKFDRFNLFNEHLLEHPVECFACGRHFKQWRNFSLHIKRHLGIKEHQCRSCGKQFVIKQKLIEHMRVHTGHAPIKCKLCNRTFKRFSNLAQHRKRYHLNRTVAKEDYVCSLCGEVFHTQAKMEWHKETHEKKPKSCPYCREKFIHRNSLTRHIRLSHTDKYAKLENKTEPCSICQQPYTKTSMRRHMETHTKERMAYACGICNKRFTTNWNLKQHKWTHANPTMKPFQCTYCPSAFVRESDFVTHVNAHRSIRPYTCNHCGSQFIRKYNWIRHTREHELDKGHRCDVCGRQFHRKYYLTEHKRIHTGERPFACNICGKTSATKTNHNKHVRIHHARDPLTAEG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -