Basic Information

Insect: Anopheles stephensi
Gene Symbol: -
Assembly: GCA_013141755.1
Location: CM023248.1:40998953-41001619[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2.4 1.4e+02 3.0 0.1 2 16 9 23 9 25 0.80

2 15 0.0004 0.023 14.9 0.1 2 23 99 121 98 121 0.96

3 15 0.0016 0.091 13.0 2.8 1 23 130 153 130 153 0.94

4 15 0.011 0.61 10.4 5.6 3 23 161 181 159 181 0.97

5 15 7.2 4.2e+02 1.5 0.4 3 23 186 207 185 207 0.82

6 15 4.8 2.8e+02 2.1 5.5 1 23 212 235 212 235 0.94

7 15 9.1 5.2e+02 1.2 3.0 1 23 242 272 242 272 0.80

8 15 0.0011 0.066 13.5 2.0 1 23 393 416 393 416 0.91

9 15 1e-05 0.00059 19.9 1.7 2 23 422 443 421 443 0.97

10 15 0.00012 0.0072 16.5 5.4 1 21 483 503 483 504 0.95

11 15 0.00014 0.0081 16.4 1.3 2 23 538 559 537 559 0.96

12 15 1.3e-06 7.7e-05 22.7 0.5 1 23 565 588 565 588 0.96

13 15 1.8e-07 1e-05 25.5 3.8 1 23 594 617 594 617 0.97

14 15 0.00058 0.034 14.4 0.3 1 22 623 644 623 646 0.89

15 15 4.7e-05 0.0027 17.8 1.4 1 23 651 674 651 674 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2.4	1.4e+02	3.0	0.1	2	16	9	23	9	25	0.80
2	15	0.0004	0.023	14.9	0.1	2	23	99	121	98	121	0.96
3	15	0.0016	0.091	13.0	2.8	1	23	130	153	130	153	0.94
4	15	0.011	0.61	10.4	5.6	3	23	161	181	159	181	0.97
5	15	7.2	4.2e+02	1.5	0.4	3	23	186	207	185	207	0.82
6	15	4.8	2.8e+02	2.1	5.5	1	23	212	235	212	235	0.94
7	15	9.1	5.2e+02	1.2	3.0	1	23	242	272	242	272	0.80
8	15	0.0011	0.066	13.5	2.0	1	23	393	416	393	416	0.91
9	15	1e-05	0.00059	19.9	1.7	2	23	422	443	421	443	0.97
10	15	0.00012	0.0072	16.5	5.4	1	21	483	503	483	504	0.95
11	15	0.00014	0.0081	16.4	1.3	2	23	538	559	537	559	0.96
12	15	1.3e-06	7.7e-05	22.7	0.5	1	23	565	588	565	588	0.96
13	15	1.8e-07	1e-05	25.5	3.8	1	23	594	617	594	617	0.97
14	15	0.00058	0.034	14.4	0.3	1	22	623	644	623	646	0.89
15	15	4.7e-05	0.0027	17.8	1.4	1	23	651	674	651	674	0.96

Sequence Information

Coding Sequence: ATGCACCAACTGCATCCCGTAGCTCAGTGCAAATGGTGCGGCAAACTTTCAAACGACTGGCGAGCATTCAACGCCAGTGCGGTTGTCTCGGGAAAAGATGTGATAATTCGTGAGATGGTCGATGTTTTCCAGCTGCCTCAGGGTTGGAATACTGATCCGGACGATGGGATATGTATCAAATGCTTGGAACGATTAGAATACTGCTACCAGTTCTATGGAACGTTACTTGCTACAGCTGCAAAGGAAAGCACTGTGTCCAGCGAACTAACACCCATAGAGGCGCGCTCCTTTGTAAGGTGTGCTGGCTGTGATGTTTCATTTCCCTCCCAGCTAGAGCTAGAAAAACATGCCAAAACTCAACATCCAAATGGAAGCGTACACCAGTTTCATTACTGTCGGGTGTGCAACAAATCGTTTAAAACCAACCGGGGCATGCTACAGCACCGTGCAATCTATCACGACGCGCAGGAAAGCTACGGCTGTCACATTTGCGAACGACAGTTCCTTACCAAAACCAACTATCGAAACCATATGCGCCATCATCAAGATCGAGTGTGCAGTTTTTGTAACAGCGGATGGATAACCGACGCCCACCTGCTGGAACACGTGCGCACCAGCCACACGGATCGGCTGTTTGTGTGTCGGTTTTGCAACCGAAAGGAGCAGCTAAAGAAGTGTCTTAATCGCCATCTACGCACAACCCACCAGCAGGAAACGAATCCTTACTTCTGTGGCCACTGTGGGACCACGGCCGCCGCCGGCAGTTGTTCGTTCGAGAGTATGCAACTGCTAACCGATCATTTGCAGCAAGTACACCGCGAGGATCATGGCGAGACAGTTGACGAAAAGAATGCTTACGGGGCTATTCTGCACGACTCTCTGTTTTCGAAGGAGCTCGATTTACCAGAAATGGATGAAATCGTTAAGGAGCAAGAGCTGTTTCTGCAAAACTTCCATCTGATTAGGAGCGGCCATGAGAAGCAAGAATTTTCAAGCAAGAACCCATCGGAACCACGCATCGATCAACGCATGGTGCTGGAAGATTTTCTCGACGAAGCGTTCGAGAACGATGAAATCTGGAACAAGTACATCGAGAACGGCGAGGAGTATCTGATCGACGATTACGATTTCTATTTGAAAGGAGCAGAAACTTCCTCGGAGCAGGCGTTGTGCGCGTATCTGTGCCCACAGTGTCAGCGAGGGTTTCAAAAGCAACATCATCTGACCGTTCATCTTGCCGAGGACCATGATGTACCCAGCATGGTGTGTAACGATTGTGGAGCCAGCTTTACGCGTGTTTCGCACTATCGCACTCATCGGCGGGAGCATCTGAAGGACAATGTGCGCTTCCGGGAGAGTAACATTCCCGAAATGGAGGAAGCTTTGTCGCTGGTGCAAACCTCATCGCTCGATTATTCGGTGCACGAGGAAGAAGGTGGGTACGTGTTCACGTGCAATCTGTGCGATCGCACATTCCAGCGGAAGCACAACCTGGAAAAGCACCGATGCCAGTTCTACGAACGTCACACCCCACCACAGCCAGCGGATGATGGAGCGACCCGGCAGGCGGGCAATGGAGCGCAGGATTTGCCTGCTAACCGGGAAGTCATCTACTGTATGCTTTGTGATCGTCGGTTTAGCTCAACCTCTGGGCTGAAATATCATCTGAAACGACACACGGGCATCAAAGCGTTCGCGTGCTTGTACTGCGAAAAACGGTTTACAGCCAACTCGAATCTGAATGCACACATGCGGAACGTGCATAGCCAGCGGAAGGACTATCGGTGCACCGAGTGCAACGAATCGTTTACTACCAAAGATCACCTTAACAAACATCAGCGCGCACGGCATCGTCAGGAGCGCGCATTCGTGTGTGGCGAATGTGGCAAGAGCTACCTGCAACGATCGCATCTGAACGAGCACGCAGCAGCGAGCCATCGAGACGATAGATACATGTGCAGCGTTTGCAACGGGTCGTACGTTAGCAAAAGTTCGCTGAaacgacatcagcagcagaaacaTGGCGTTTCGTAA
Protein Sequence: MHQLHPVAQCKWCGKLSNDWRAFNASAVVSGKDVIIREMVDVFQLPQGWNTDPDDGICIKCLERLEYCYQFYGTLLATAAKESTVSSELTPIEARSFVRCAGCDVSFPSQLELEKHAKTQHPNGSVHQFHYCRVCNKSFKTNRGMLQHRAIYHDAQESYGCHICERQFLTKTNYRNHMRHHQDRVCSFCNSGWITDAHLLEHVRTSHTDRLFVCRFCNRKEQLKKCLNRHLRTTHQQETNPYFCGHCGTTAAAGSCSFESMQLLTDHLQQVHREDHGETVDEKNAYGAILHDSLFSKELDLPEMDEIVKEQELFLQNFHLIRSGHEKQEFSSKNPSEPRIDQRMVLEDFLDEAFENDEIWNKYIENGEEYLIDDYDFYLKGAETSSEQALCAYLCPQCQRGFQKQHHLTVHLAEDHDVPSMVCNDCGASFTRVSHYRTHRREHLKDNVRFRESNIPEMEEALSLVQTSSLDYSVHEEEGGYVFTCNLCDRTFQRKHNLEKHRCQFYERHTPPQPADDGATRQAGNGAQDLPANREVIYCMLCDRRFSSTSGLKYHLKRHTGIKAFACLYCEKRFTANSNLNAHMRNVHSQRKDYRCTECNESFTTKDHLNKHQRARHRQERAFVCGECGKSYLQRSHLNEHAAASHRDDRYMCSVCNGSYVSKSSLKRHQQQKHGVS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -