Basic Information

Insect: Anopheles stephensi
Gene Symbol: ZNF219
Assembly: GCA_013141755.1
Location: CM023248.1:125694-129645[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 2.3e-05 0.0013 18.8 0.6 1 23 132 154 132 154 0.99

2 11 0.0001 0.0058 16.8 2.8 1 23 160 183 160 183 0.96

3 11 2.2e-06 0.00013 22.0 0.4 1 23 189 211 189 211 0.99

4 11 6.3e-06 0.00036 20.6 0.2 1 23 217 239 217 239 0.98

5 11 0.0087 0.5 10.7 3.0 1 23 245 267 245 267 0.98

6 11 9.6e-06 0.00056 20.0 3.1 1 20 273 292 273 296 0.95

7 11 0.03 1.7 9.0 5.5 1 23 302 322 302 322 0.97

8 11 4.6e-06 0.00026 21.0 0.0 3 23 330 350 329 350 0.98

9 11 1.6e-05 0.00095 19.3 1.1 1 23 356 378 356 378 0.99

10 11 1.1e-05 0.00062 19.9 1.0 1 23 384 407 384 407 0.97

11 11 0.0025 0.15 12.4 0.6 1 20 413 432 413 433 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	2.3e-05	0.0013	18.8	0.6	1	23	132	154	132	154	0.99
2	11	0.0001	0.0058	16.8	2.8	1	23	160	183	160	183	0.96
3	11	2.2e-06	0.00013	22.0	0.4	1	23	189	211	189	211	0.99
4	11	6.3e-06	0.00036	20.6	0.2	1	23	217	239	217	239	0.98
5	11	0.0087	0.5	10.7	3.0	1	23	245	267	245	267	0.98
6	11	9.6e-06	0.00056	20.0	3.1	1	20	273	292	273	296	0.95
7	11	0.03	1.7	9.0	5.5	1	23	302	322	302	322	0.97
8	11	4.6e-06	0.00026	21.0	0.0	3	23	330	350	329	350	0.98
9	11	1.6e-05	0.00095	19.3	1.1	1	23	356	378	356	378	0.99
10	11	1.1e-05	0.00062	19.9	1.0	1	23	384	407	384	407	0.97
11	11	0.0025	0.15	12.4	0.6	1	20	413	432	413	433	0.92

Sequence Information

Coding Sequence: ATGAAGAAATCAACGCGTCAAACCCGAATGTCTCGGTACGTGGGTAAGCATTCGCCAAAGATTGCAACCCCAGATGAAGGCAACAATAACgtcaacatcagcagcaaggGCACCATCCCAACTCCCGCGAAGATGTCGAGTGGCGAGGAAGAAATGTCCGCAATGGAACTTCCTTCGTTCATTGCGGAAAAACCGATCAACTACAACGAAACATCTGCCCACTGCGATGACGAGGATGATAAGTCGGATGTGAAGAAGCTAGTCAATGCAGTTGACGAAGCAGGCGAGGAAGCGGACGGTGCCGAGTCTGGTAGTGGCACCGATGCAACCCTATCCTCTGCCGGGGGATCGGCGTCGTCGAAGCGCGGTCGAAAGCGCCAAGAACGGAAGCTATATCAGTGCGAAGTATGCCAAAAGGAGTTCATGGGCACGAACGATTTGCGCAAACATTTGCGTATACACAATGATGAACGGCCGTACCCATGTCCGCACTGCAAAAATCGTTTTCGACAGGCAGGATGTCTGAAGAACCACATTGCTTCGCAGCACGGTACGGATGAGCAGTATACGTGCGATCTTTGTGGAAAATCGTTCCCCATTAAGGAGCGGTTACGATTACATATGCGCATTCATACGGGCGAAAAACCGTACAGCTGTTCGCTTTGCCCGAAAACCTTCGCACGTGGTGGACAGCTAACGCAGCATCTTGCTACACACAACGGGGTCAAGAAACACAAGTGTGATCAATGCACGGCAGCTTTCTCTTGTGCCGCTAACCTGAAAATGCACCTTAAAAGCCACATGGACATCCGCGACTACACGTGTCACATTTGCGGTCGAGGATTCTATCGACCAGATGCACTTAAAAAACATCTTCTCTGTTACCATGCTAATCTCAAAGCGTTCCACTGCAACATATGCAACAAAATGTTCAAAGGACACTTGCCGCAGCATATGCGGACGCATCTGAAGGTGCGTCCGCACggttgtgctgtgtgtgggGCGGTTTTCTCACAAAGGTCGCAGCTGATCGTTCACCAGCGCATTCATAGTGGTGAACGCCCATACCGCTGTCAGGTGTGCTGGCAAGCATTCGCTCACTCAAGCGTTCTAAAGTTGCACATTCGTAAACATACGGGCGAGAAACCGTTTGAGTGTCCGCTATGTAGCTCGAGCTTTTCACAGCTACCACATTTGAAGAAGCATATGCTCTCCATTCACCAGCAGGATAAATCGTACTTATGTCAAAAGTGTGGagaatttttcaaaacaaaaatggactaccAACTACACGTGACGGCGTGCTACAAAGATCCGGCCGCAGTAAAAAATCTCGACAACATGCTGGACCCCATGTATCGACCGACTGAAACTAACGGCATAGATCCCCCCATGACCATTTCACGCATGCGATTTCTGGTGGCAATTTTGTTGAAGAAAATATCCAGCGAGGATCGACTGAAGGAGCTGGGCTTCGATAAGCGACTTATTGACAACGTTCTAATCGACTCACTGAAGTGTGCTGGGCGCAAGGTTTGCGATGACAAGTCATACGATCCACTGGAACGATTGAAGCTAAACGTACAGGAACTACTTGAATGGACTGTACCGCCAAACTACATGAAAGAATTTCGCGGTGCCAATCGTAGCACTGAGGAGTTACTTGAGGAGCTCACCAACTAA
Protein Sequence: MKKSTRQTRMSRYVGKHSPKIATPDEGNNNVNISSKGTIPTPAKMSSGEEEMSAMELPSFIAEKPINYNETSAHCDDEDDKSDVKKLVNAVDEAGEEADGAESGSGTDATLSSAGGSASSKRGRKRQERKLYQCEVCQKEFMGTNDLRKHLRIHNDERPYPCPHCKNRFRQAGCLKNHIASQHGTDEQYTCDLCGKSFPIKERLRLHMRIHTGEKPYSCSLCPKTFARGGQLTQHLATHNGVKKHKCDQCTAAFSCAANLKMHLKSHMDIRDYTCHICGRGFYRPDALKKHLLCYHANLKAFHCNICNKMFKGHLPQHMRTHLKVRPHGCAVCGAVFSQRSQLIVHQRIHSGERPYRCQVCWQAFAHSSVLKLHIRKHTGEKPFECPLCSSSFSQLPHLKKHMLSIHQQDKSYLCQKCGEFFKTKMDYQLHVTACYKDPAAVKNLDNMLDPMYRPTETNGIDPPMTISRMRFLVAILLKKISSEDRLKELGFDKRLIDNVLIDSLKCAGRKVCDDKSYDPLERLKLNVQELLEWTVPPNYMKEFRGANRSTEELLEELTN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00100454;
90% Identity: iTF_00105288;
80% Identity: -