Basic Information

Insect: Anopheles stephensi
Gene Symbol: -
Assembly: GCA_013141755.1
Location: CM023248.1:15345733-15350134[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.046 2.7 8.4 0.3 1 23 372 394 372 394 0.96

2 12 0.00036 0.021 15.1 0.8 2 23 407 428 406 428 0.97

3 12 0.00021 0.012 15.8 2.2 2 23 437 458 436 458 0.96

4 12 1.6e-06 8.9e-05 22.5 1.0 1 23 464 486 464 486 0.99

5 12 1.1e-05 0.00066 19.8 1.8 1 23 493 515 493 515 0.98

6 12 4.6e-06 0.00026 21.0 1.6 1 23 521 543 521 543 0.96

7 12 1.9e-05 0.0011 19.1 0.6 1 23 549 571 549 571 0.97

8 12 5.1e-06 0.00029 20.9 0.4 1 23 577 600 577 600 0.96

9 12 0.00027 0.016 15.4 2.6 1 23 606 629 606 629 0.96

10 12 1.5e-05 0.00086 19.4 1.5 1 23 635 657 635 657 0.99

11 12 1.6e-05 0.0009 19.4 0.7 1 23 663 685 663 685 0.96

12 12 0.00026 0.015 15.5 0.2 1 22 691 712 691 715 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.046	2.7	8.4	0.3	1	23	372	394	372	394	0.96
2	12	0.00036	0.021	15.1	0.8	2	23	407	428	406	428	0.97
3	12	0.00021	0.012	15.8	2.2	2	23	437	458	436	458	0.96
4	12	1.6e-06	8.9e-05	22.5	1.0	1	23	464	486	464	486	0.99
5	12	1.1e-05	0.00066	19.8	1.8	1	23	493	515	493	515	0.98
6	12	4.6e-06	0.00026	21.0	1.6	1	23	521	543	521	543	0.96
7	12	1.9e-05	0.0011	19.1	0.6	1	23	549	571	549	571	0.97
8	12	5.1e-06	0.00029	20.9	0.4	1	23	577	600	577	600	0.96
9	12	0.00027	0.016	15.4	2.6	1	23	606	629	606	629	0.96
10	12	1.5e-05	0.00086	19.4	1.5	1	23	635	657	635	657	0.99
11	12	1.6e-05	0.0009	19.4	0.7	1	23	663	685	663	685	0.96
12	12	0.00026	0.015	15.5	0.2	1	22	691	712	691	715	0.92

Sequence Information

Coding Sequence: ATGAGCGATCATGATGTTGCACAAGACGACGAGATTCTTGTTGACGATGGTACCGGTCTGTACTCGCACTGCTATTTGTGCCACACTCCAGCCGTGCAAGATGAATTTTGTCAACTTTTCCCCGAGCCGAACTTTTTCTCGCCCGCTAAAACGATATGTGATGTGCTGGATGTAGCACTGATGCCGGAACTGTGCCACTCGCTGATCATTTGCAAGAGCTGCAATGCACTGTGCGCGGAGTATCAGTCGTTGGTAGAACGTATGGAAATGATCCACAGGACCATCACAACGACCTACAATCAAACCGTGATGAAGCTGACGGGGCTGACGGAGACGGACATCAAGGAAGGGTTGGTGGCGGTTGAGTACAACGACAACCTTGACACGGAACTGCACACCTTCAACAAAGAGCTGATGTCTATGGAAGAAATGTTTGGAGAGCTAAATCCGGACGAGATACAGGTGGACCCATCCTACGAGACCCTGCAAGATAACGCTTCTCATCTGGAACAAAACGATCCGGACGAGCCGGCGGCAGAAGACTGTGTGCAGTTTATAAAGGTCGATGAGCACGTTACACCCCTGCTGCCGACCGATTCCGACGAGATGGTGCAGAAGAATGTCGGTGACGAATTTTCTGGCGAAGAAACGCTCCAGCGGTATATAATCGATACGGATGAAACGATCGTGGAGGTGGATGAAGAAGATGGAACCGCAATCTATTGCGTCTACAATGACGTTGTAGAGTCGTTTAGTGACCCGGAAGAGCAGCCGGAGACGGCGGTACCAGTGCTGGATGGTGCAACGACCGAAAATGGGTTTCTGGAGAATGATGATGCTATCATCGACGGTGCATCGCAAGCAAGTGAAAGTGGAGTAAACGAGATTCAGGAATCCGTATCTGCAACCTCACTGCTGCTGAATGAGGTAGAGCTCTCCGGAGCAGGATCTCCACCACTAAACGAGAAAGATGATTTAAGGCCGtattatataaaaatagaaaactactactactgcacCGTCTGCCCGACCGACAACGACGAAACAACGGTTTCTACGAACGGCATCAAGCTGATGGCAGAACATTTAAGCAAAGAGCACAATCTACTAGCCCATATCTGCCAACTGTGTGATGCCATATACTTTCAGCGCGAAGCTTACGTTAACCACCTTGCCACACACGCCACACAAGAAGAAAGTGCGCTTGGGAGTGAACTGACCTGTGATCAGTGCGATGCCACGTTCACCAAACAAAATGCGCTTGACCAGCACCGCAAGTCGCACCCGAGCGGAAAGAGCAAGGTGTGGCACTGTGAGCTGTGCGACAAGAAGTACACCTCGAAAGCGTTCTTTGAGGTGCACATGAACAAGCACGCCGGTTTGCGGCCGTTCAAGTGTACCGTGTGCTCGAAAGATTTTAGCTCCAAGTACGCGCTGGCAGTGCACCTGAAAACACACTACGATCGTCCCCGTACGTTCGTGTGCAAGGAGTGTGGGAATGCGTTTTACAGTCGGCACAATTTGGTACAGCACGAACGGACGCATCGGGCCGAGCGAGAGTACGAGTGTGGCGATTGTGGGAAGAAATTTTTCACCCAGCACAATTTGAACGTACATAAGGTTATTCACAGTAGCAACAAGGCTTTTGCATGTCGCCAGTGCGGAAAGAAGTTCGCCCGGAAAGCGGAAGTAAGAGACCACGAGCGGACGCACACAGGTGAGAAGCCATTTGTGTGTGATATGTGTGATTTGGCGTTTGCGCAACGGTCCAACCTTAACTCCCACAAGCGGCTAACACATTTCAACGACAAGCGCTACAAATGTGACCTATGCGGGGCTTGCTTTAAACGGCGCAGGCTGCTCGACTATCATACGCGAGCGATGCACACGGGAGAGCGGCCGTACAAGTGTGATCTGTGTCCCGCTTCCTTCGTGTATCCGGAACActttcaaaaacacaaacgcatTCACACCGGCATCAAGCCGTACGCGTGCGAGGTGTGCAACAAAACGTTCACCAGTCAGGACAATCGGAATGCGCATCGTTACGTGCACAGCGACAAGAAACCGTACGAATGTGTGACGTGCGGTACTGGGTTTATGCGTAAGGCGCAGCTCTACACGCATATGCAGGAGCAGGGCCACCTGAACGACACGATCGTGGTGAATCAGCCGCGGATCAGTGCGAACGATGTGATCGAGTTCGAGACGGAATCGTTGGTGGTCGATGGGCAGGCGGATGGTGAACAACACCGGGATGTGGAGGTCGGCTCGGACGAtgaacacgcacacataacGTTCATTTGCGATGAGGAGTACGTGGATGGGGTTTCAGAAATGGAATAG
Protein Sequence: MSDHDVAQDDEILVDDGTGLYSHCYLCHTPAVQDEFCQLFPEPNFFSPAKTICDVLDVALMPELCHSLIICKSCNALCAEYQSLVERMEMIHRTITTTYNQTVMKLTGLTETDIKEGLVAVEYNDNLDTELHTFNKELMSMEEMFGELNPDEIQVDPSYETLQDNASHLEQNDPDEPAAEDCVQFIKVDEHVTPLLPTDSDEMVQKNVGDEFSGEETLQRYIIDTDETIVEVDEEDGTAIYCVYNDVVESFSDPEEQPETAVPVLDGATTENGFLENDDAIIDGASQASESGVNEIQESVSATSLLLNEVELSGAGSPPLNEKDDLRPYYIKIENYYYCTVCPTDNDETTVSTNGIKLMAEHLSKEHNLLAHICQLCDAIYFQREAYVNHLATHATQEESALGSELTCDQCDATFTKQNALDQHRKSHPSGKSKVWHCELCDKKYTSKAFFEVHMNKHAGLRPFKCTVCSKDFSSKYALAVHLKTHYDRPRTFVCKECGNAFYSRHNLVQHERTHRAEREYECGDCGKKFFTQHNLNVHKVIHSSNKAFACRQCGKKFARKAEVRDHERTHTGEKPFVCDMCDLAFAQRSNLNSHKRLTHFNDKRYKCDLCGACFKRRRLLDYHTRAMHTGERPYKCDLCPASFVYPEHFQKHKRIHTGIKPYACEVCNKTFTSQDNRNAHRYVHSDKKPYECVTCGTGFMRKAQLYTHMQEQGHLNDTIVVNQPRISANDVIEFETESLVVDGQADGEQHRDVEVGSDDEHAHITFICDEEYVDGVSEME

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -