Aste009249.1
Basic Information
- Insect
- Anopheles stephensi
- Gene Symbol
- su(Hw)_1
- Assembly
- GCA_013141755.1
- Location
- CM023248.1:78969094-78973189[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.077 4.4 7.7 1.0 2 20 94 112 93 114 0.91 2 13 0.001 0.058 13.7 0.7 2 23 170 192 169 192 0.95 3 13 0.34 20 5.7 3.5 1 23 198 220 198 220 0.98 4 13 0.002 0.12 12.7 1.6 1 21 226 246 226 247 0.92 5 13 7.2e-07 4.2e-05 23.6 0.1 2 23 261 282 260 282 0.96 6 13 9.7e-08 5.6e-06 26.3 0.7 1 23 292 314 292 314 0.99 7 13 1.8e-05 0.001 19.2 0.2 1 23 320 342 320 342 0.98 8 13 5e-05 0.0029 17.8 0.7 1 23 348 370 348 370 0.99 9 13 1.4e-06 8e-05 22.7 1.3 1 23 376 398 376 398 0.97 10 13 5.2e-05 0.003 17.7 1.0 1 23 404 427 404 427 0.96 11 13 0.00014 0.0079 16.4 0.5 1 23 433 455 433 455 0.97 12 13 0.00021 0.012 15.8 1.3 1 23 461 483 461 483 0.99 13 13 3.2e-05 0.0018 18.4 3.7 2 23 490 512 489 512 0.97
Sequence Information
- Coding Sequence
- ATGATGGTAGGCAGTCGACGATCCGTTGTCGGTGGAGTCCGTAGCGGTGGGGTGAAGAAGGAAGAGATTTTGGTAAACGTGCAGGTGAACGGTAACGACGAGATTGACCTGGTGCCGGTCAACAAGAGCGCGGATTATGGGAGAGGATCGAGCGACGATCGAGACGgtgatgaggaggaggaggaggactaCGAAGATCTGTCCGACAATCCGGACTCGGATCCGGATCTGCTCGAGACGGAGGACGGTCGGTTGATACTGGACATGAAGCGCAGCAAGTACTGTGGCAGGTGTAAAAAGATTTTCAAAACATCAGCGGAACAGAAAGCACACAAATACAAGTGCCCGGGCGTTGTGGATGAGGTGCAGGACGTCATCCTGAAGGAGCGTAAGGCGGCCAAGCATGCGAACCCGGGCGAAGAGTTCCACAAGTACTGCAATCCGAACCCGGACAATCCGTGCTACTGCTGCGGTGAGGATGTGAGCACCGCACACGTCGGCCACATCCGCTGCAAGTTCTGTCCCAAATCGTTCAAAGCGTACGAGTACATGGAGCGACACCTGAGCTCGATCCACTCGGAGTCGGACGCATTTCCGTGCTGCTACTGCAACGCCAAGTGCAGCACGCAGGAAATTCTGGACGAGCATCTGAAGACACACGACGAGGGCAAACCGTACGCGTGTATGGCGTGCGGTAAAGATTTTACCCGCCGCTACCATCTGGACCGCCACGAAAAGCACACCAAGTGCGGGATCGTTCCCAAGGAGGTGGAGGTGCTACCGTGCGAGGTCTGTGGCAAGGAGTTTACGCGCATTGACAATCTGCGGGAACATTTGCGTTCGCACATGGGGCAAGGGGCACGCAAGCGGGATTACCAGTGTCCGTACTGCTCCAAGTCATTCTACGGCTCATCGTTGCTGAACATAcacatacgcacgcacacgggCGAGAAACCGTTTCCGTGCGATCTGTGCCCGATGTCGTTCCCGTCGACCGGTGCGCTGCGGAAGCATCGGCGCAAGCATACGGGCGAACGGCCGTACCGCTGCGACGAGTGTTCTGCAACGTTTGCCGCGCGTGAAACGCTTAACCGGCACCGGAAAACGCACACCGGCGAGAAGCCGCACGTGTGTCAGGAGTGCGGCAAACGGTTCATCCAAGCGACACAGCTCCGGTCCCACATGCTCAATCACAGTGGCGACAGTGCGTTCCAGTGCAGCGAGTGCGATGCGACGTTCAATCGCAAAGCCCGGCTCACGGAGCACATCAAGTTCACGCACAAGGGAGAGCAACCGTTCGAGTGCGAGAAATGTTCCAAAACGTTCCTGCGCAAGGATGATCTCGCACGCCACGAGCTGATCCATTCGGACGTTAAACCCTACGAATGTTTGGTGTGTAGGAAatttttcaccaccaaaaACGCTATCCTGTTGCACCAGCGGACGCATCTGGAGGAAAATCCGGTCCAGTGTAAGGTTTGCTCCGGCACCTTCAAACGGTCCGACTGTCTGATGCGGCACATGCGTACAAAACACCGCGACTTTTTGGACAAAATTATCGACGATACCGAGaaggaaaagatggaaaagcTGACCACCACCAAGCGAGAAACGGAAAAGGAAGCGGTGGTGGAGATAGACGGTGCCATCTATCAGATCACCACGATGGACGATGCACCCGCGAAGGGGACCGCTTACACCGGCAACAACCAAACGGTGGAGGTGTTCGAGGTGGTAGAGCTCCCGGCAAGCGCTTCGGACGCGATACCAAACACACTGCCGACCACCTCGGTACCGTACGAGCTGGTACCGGTTGTGGATGATGCGGAAGTAATACTGGGCGACAGCAGTCCGGTAGAGTTTGTCGGTAAAGCAAACGCTGCAAACGACGTGGTTgtgaagaaggaggaggatTCGTTCAAAAAGGTAAAGTCCCCGCCCAAAGCGACTGTCGTTTCAAAACCAAGCGAACCCGTTGCACCGAAGGTTGTTGGTAAAGCCAGCGAAGGAGAACCGTCGCGCAAGAGCGTTCCAAGCACTTCGAAACCAACTGCCCCGATAAAACCGAAGACGGAACATGTAGTAGCTGTGCGTGCGAGCAATGAACCACCACAGAAAACGCCCCCGAAGCTAACGAAAGAGATTGCGCGCGAAAAGGAGGAACCCAGCACCAAGCTGGCAAAGAAGCCGGCTACATTACCGACCGCCCGACCGAAAGAGGCCAAGAGCAGGGTGGTGGAGGAAACGAAGTTGAAGCGCAAACGTGAACCCAAACCGGCCACCCCGAAGCGAATGCGCCCGGACGAGGACAGCATTCCGATCTTCCTGAGCGACGATATGCTCGAGCAGAAGATTTCCGAACTGCTGCAGATGCTGATGGGGGAGGATATGTTGCGCAGCTTCGGTTGGCCGAACGCACCGGTCGAGGTGGTGCTCGGGCGCGTCATCCAGGGCTGCGGTCATCAGCCGGCAAAGGGCGAGGAGGCCGGTGACCATACGACGCGCATGCGAGAAAACACCAAGATACTGTTTTCCGTCACGATGGACGATGACGACATTAAGGCTTTGCTGAACAATCACACGGTCGACGAGGTGATCATGCACGTGCTGAAGAACAAGTAG
- Protein Sequence
- MMVGSRRSVVGGVRSGGVKKEEILVNVQVNGNDEIDLVPVNKSADYGRGSSDDRDGDEEEEEDYEDLSDNPDSDPDLLETEDGRLILDMKRSKYCGRCKKIFKTSAEQKAHKYKCPGVVDEVQDVILKERKAAKHANPGEEFHKYCNPNPDNPCYCCGEDVSTAHVGHIRCKFCPKSFKAYEYMERHLSSIHSESDAFPCCYCNAKCSTQEILDEHLKTHDEGKPYACMACGKDFTRRYHLDRHEKHTKCGIVPKEVEVLPCEVCGKEFTRIDNLREHLRSHMGQGARKRDYQCPYCSKSFYGSSLLNIHIRTHTGEKPFPCDLCPMSFPSTGALRKHRRKHTGERPYRCDECSATFAARETLNRHRKTHTGEKPHVCQECGKRFIQATQLRSHMLNHSGDSAFQCSECDATFNRKARLTEHIKFTHKGEQPFECEKCSKTFLRKDDLARHELIHSDVKPYECLVCRKFFTTKNAILLHQRTHLEENPVQCKVCSGTFKRSDCLMRHMRTKHRDFLDKIIDDTEKEKMEKLTTTKRETEKEAVVEIDGAIYQITTMDDAPAKGTAYTGNNQTVEVFEVVELPASASDAIPNTLPTTSVPYELVPVVDDAEVILGDSSPVEFVGKANAANDVVVKKEEDSFKKVKSPPKATVVSKPSEPVAPKVVGKASEGEPSRKSVPSTSKPTAPIKPKTEHVVAVRASNEPPQKTPPKLTKEIAREKEEPSTKLAKKPATLPTARPKEAKSRVVEETKLKRKREPKPATPKRMRPDEDSIPIFLSDDMLEQKISELLQMLMGEDMLRSFGWPNAPVEVVLGRVIQGCGHQPAKGEEAGDHTTRMRENTKILFSVTMDDDDIKALLNNHTVDEVIMHVLKNK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00103818;
- 90% Identity
- -
- 80% Identity
- -