Aste013636.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles stephensi
Gene Symbol
Zbtb41
Assembly
GCA_013141755.1
Location
CM023248.1:5281172-5285777[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 2.2e-06 0.00013 22.0 2.6 1 23 225 247 225 247 0.99
2 15 0.019 1.1 9.6 0.5 1 23 253 276 253 276 0.98
3 15 1.9e-05 0.0011 19.1 0.8 1 23 296 319 296 319 0.94
4 15 0.021 1.2 9.5 3.8 1 23 325 348 325 348 0.95
5 15 1e-05 0.0006 19.9 0.4 1 23 503 525 503 525 0.98
6 15 0.00013 0.0073 16.5 0.7 1 23 531 553 531 553 0.99
7 15 0.032 1.8 8.9 3.2 1 23 646 668 646 668 0.97
8 15 1.1e-05 0.00063 19.8 1.0 1 23 674 696 674 696 0.99
9 15 0.00042 0.024 14.8 0.0 1 23 785 807 785 807 0.95
10 15 0.0012 0.07 13.4 3.4 1 22 813 834 813 837 0.90
11 15 6.2e-07 3.6e-05 23.8 0.8 1 23 986 1008 986 1008 0.99
12 15 0.00014 0.0082 16.3 4.0 1 21 1014 1034 1014 1036 0.94
13 15 0.00026 0.015 15.5 0.8 1 23 1274 1296 1274 1296 0.98
14 15 1.7e-06 9.8e-05 22.4 2.6 1 23 1302 1324 1302 1324 0.99
15 15 0.0041 0.24 11.7 0.9 2 23 1331 1353 1330 1353 0.92

Sequence Information

Coding Sequence
ATGGAGCTAAAGGCGGAGAAAAAAGACCATGACGACGATGAAAACGGTGCACGACGACGGAgacagcatcatcagcatcgtaGCACCACCGCTGCAGCTGCATCTGCTACTGCGATGGATGTCGATGCAGCACCATCAGAACCAGCAGCACCGAATGGCGGTAATGGCGATGAGCTTTCGGATCAGGAGATTGTGGAAGTTGGCATTGATGAGGATCACATCAAGTTTCTCACCAGCATGCACTCGGGCGACGAGGAGCCGACGAGCAACGGGCACCGACCACCATCGATGGTGCCTCACCGAACCGTGACGATTGGGGTCACCGGAAACGGGCGGCAAGTGCGGACAAACGTCGATAGCGGTGTCAGCACGGGCGGAAAGTATCGCCGTGCCGCCATGTTCCACGTACCAGCCCATCGGAATGGTGCTTTGAACGGGTTGAAagtgcaccagcagcagcgcggAAGCAACGGAGCACTACCAGCACCAACGCTTGCCGCCGCCGGGTACAGTGAGGATGAGTCGGATGACGACGGTgaggaagacgacgacgacgacgacgacgacgatgacgatgacgacgatgatgacgacgaagaTGTGATGGTCGTCGCCGCAAACATCCTATCGAAGACGGCACAGAGGTCATCGTTGCTTGGCACCGGGCGGACGTACCAGTGCGACGTGTGTCCACGGATATTCCATCGGCCGGACCATCTGCGTTACCATATGCGTATCCACGAGAAGAACAACCCGTTCGAGTGCAAGCTTTGCTTTAGTGTGTTCGCGTCCGATCCTGCCTTCGCGCACCACATTCGCACCGAGCACGCCGGGATGGGGCTAGCGGATGCGTTACCGCCCGTACCCGAGACGGAGGCGAACTTTTTCGCCTGCACCTACTGCGACAAATCGTTCAAGGATGCGGTTGAGCTGGAAGAGCATCTGCATCAGCAGCATCTCGGCGAGCGGCCGTACAAGTGTAACATGTGCCCGAAAGCGTTCATCCGGATGGATTTCCTGCAGTGTCACTACCAAAAGTACCACAGCTTTCACCCGatggacgaggaggaggaggaggaggaggacggtGAGGAGGAGACGCACCATTTGCCGATGGATCAGCATCTACAGCAGCATCCGCCGCACTCGCAGTGGGCAGAAAGTAGAGCAAAACGGCCACGGTTGATGGTGCGCAAGATAGAGGATTTGGTGGACGATCGAATGATGAAGGGTGGTAGAATTGGTGGTGTTTCGAGGCGTACGTCACACACCGGCACCGGAACAAGCATTTCGAGCGACGATCATCGCGAGGacggggatgatgatgaggatggggATGACGAGGGCACGGGAGCGGAAAGTAGCGATCAGCATGGCAGATTTCTCCAGCGCAAGGATGGTTTGGTCGGTCGCTACGTTCCGCCAAAGCTGAGCGGTATACACAGCCGGTTTCTGGTGGCAATGGAAGAGCAGCATTCGAAAAAGTTGGCGGAAGAAAGTATTAAGCATCGGTGTCCGGTTTGTGACCGAGGGTTCGCTCATGAACCGGATTTGATGGCGCACGTGCGCACCCATCCCGACTTACCCACCTTCAAGTGTCCGCTGTGTGAGCTAACTTTTATCGGATCGGATTTTTTGAAGAACCACCTCAAGAAGCATGTAATCGGTAATGGGGAAGATCCGGATGCACCCGGAGCGATTGATCTGAATGCCGCTCCGCCCTCGGAACCAGCGCCCGGTGTCGGCGGAGGCTCGACGGATCCAGTACGAGCTTCACTGTCTCCCGCTGTTGGGCTGCCGGCCACGGTCAAGCTTCCCAAGCCGATCATTACATCGAAACCACCTTCCACGGGCATATCGTTGCTAAAGCCGATCGAAGAACGGAAACCTCCGGACCATCAGCAAGAGTATTGCGTGAAGACGGCCGACGGGAAGTTTATGTGTACGGTTTGTGAGCGTCTCTTCTCGCACCAGCAAACCGTGCGCATCCACTTCCGAAACCACACGAACGAAAAACCGTACAAATGCACGTTTTGTGAAGAATCCTACATTCGGTCGGACTATCTCGAGCGTCATCTGAAGGTGCACTTCAAGGATGGCATGCTGCCGGCGGTGGCGATTGCCAGTATGGCGGCTGCAGCCGCAGCCGTCGCGACTGGTGGAAGCCGGTCGGCTACTTCATCGCCGCCCCTTACGATTAAGGAGGACTCACTAGCTGAAAGCCCGGCAGCACCGGTAGCAGGAACGGCCGCGCCTATCGCAACTGGTGGCGGTTCCACCGGCAAGCCACTGATCGGTCGGGCAGGTTTGGCACCGGAAAATTATCACTTTACCGAATCGAACGATGGCCAGTTTGTGTGTAAGATCTGCGATGCCGTGTTTAATCAGGTGGCTTTACTGCGCAAACATGCCCTGGCGCACACGGAAGAAAAACCGTTCCACTGTGACATTTGCGACCGGTCGTTTAATCGGGTCGACTACCTGAAGGAACACTTTAAGTCGAAGAGGCATTTGCAGCTGGTGGCAGAAGCTGCTGCCGGTGGAGACAGTTTGCCAGCGCCAATCGGCAGCGGACGTGCGGACGAGGAAGAGGATGATTCCACGATGGAGGAAGGAATTACGTCGACCAAGCGTTCGAAAATGGTGGAGAGCAAATACAATGCAAAACAAGCGTCCATTGAGGAGGTTGGCCATGCGGCGATGACTAATGGCGAGGGGGCGCGTTCGGTGGACGTGAAGGGAAACGTTAGCAgtaacagcagtagcagcagtagtagcggtagcagcagcagccggagtagcagtagcagtcgcagcagcagtatcAATAGCAACAGGAACAACACCTCCGTTACGTCCAATCCGAGCCCGGTGAAGCAGAGGGAGGTCGGTGAGACGCGATCGGTGTTGGGCGAGTTTCATCGATCGGATTACGAGCGCACCAGCGACGGGCGGTACAAATGTAACCAGTGCGATAAAACGTTCGTGACGGCCGTCACGCTCAAGATGCACATCCGGTTGCATACGGGCGAAAAGCCTTACAAGTGTGACAAGTGTGATAAGGCGTTCATACGCTCGGATTACCTGAAAACGCACGAAAAGTGTCACCGGCAGGAATCGTTCCTAAGCATGCTATCGCTCAAGACGTCCAAGGAACCGAGTACGGCCTCGGAAGCGGGTGACTCAGATGCGGATGGTGAGCCGGGCGAGGGACAGCGCCACCATCGGGGAGGGTCTGCAGTTAATGGAGGAAGCGAGACTGCTGGTGGACAGCCCACCAAAGTGGAGATAAAAGATgaggacaccgaaggggagGAGGACggggtggaggaggaggaggacgaggaagaagaagacggagAGGAGGAAGCGGAATCAGAGGAGAGTGAGGATGAACAGGTAATTGAAGTTATGGTGAAGGAAGAGAGCTGCTCCGATAGTGAAGAGGACGACGAAGATGGCGAGAATGAAGAGGAAGACgaggaagaggatgaaaataatGAAGATGGCGAGGATGCAGGGCAGCATTCGCCGTTCGATGCGGCCAACAACAGTACAAACCGAATCGCACCCAGCACAATGATCGCGTCGCAACATCCGCGAAAGGAAAAGGGATCGAGCGGGAAGCGACGAAACCGACCGAAACACTCCGTCTCGTCTAATCGAGCTTTCGCGTCGGCGGCGGCTGCAGCGGCCACTAGCGGCGGAGACAGTAGCAACAATGGATTCGATCACGAGGACGATAGTACATCGCAAACGAGCGGGCAGCAGTACGGTAGTGGTGCCGGCGAGTTTATGTCCAACGGCCAGAAGGGCAAACACCGGTGTCCGATGTGCGATAAGCTGTTCGCTTGGCCAAAGTCGCTGAAAATCCACCTTCGGACGCATACGGGCGAGAAACCGTATCGGTGCGATGTGTGTGGCAAATGCTTTGGGCGGTCGGATAGCTTGCGAGGCCACAAGCGAACGCACACGGACGATAAGCTAATACAGTGCCATTTGTGCGACGTTAGCTGTACGACGGCGACCGAGCTGGTCCAGCATCAGTATGCGGCACACGGTTTGCAGCCGTTGGAAAGTTAG
Protein Sequence
MELKAEKKDHDDDENGARRRRQHHQHRSTTAAAASATAMDVDAAPSEPAAPNGGNGDELSDQEIVEVGIDEDHIKFLTSMHSGDEEPTSNGHRPPSMVPHRTVTIGVTGNGRQVRTNVDSGVSTGGKYRRAAMFHVPAHRNGALNGLKVHQQQRGSNGALPAPTLAAAGYSEDESDDDGEEDDDDDDDDDDDDDDDDDEDVMVVAANILSKTAQRSSLLGTGRTYQCDVCPRIFHRPDHLRYHMRIHEKNNPFECKLCFSVFASDPAFAHHIRTEHAGMGLADALPPVPETEANFFACTYCDKSFKDAVELEEHLHQQHLGERPYKCNMCPKAFIRMDFLQCHYQKYHSFHPMDEEEEEEEDGEEETHHLPMDQHLQQHPPHSQWAESRAKRPRLMVRKIEDLVDDRMMKGGRIGGVSRRTSHTGTGTSISSDDHREDGDDDEDGDDEGTGAESSDQHGRFLQRKDGLVGRYVPPKLSGIHSRFLVAMEEQHSKKLAEESIKHRCPVCDRGFAHEPDLMAHVRTHPDLPTFKCPLCELTFIGSDFLKNHLKKHVIGNGEDPDAPGAIDLNAAPPSEPAPGVGGGSTDPVRASLSPAVGLPATVKLPKPIITSKPPSTGISLLKPIEERKPPDHQQEYCVKTADGKFMCTVCERLFSHQQTVRIHFRNHTNEKPYKCTFCEESYIRSDYLERHLKVHFKDGMLPAVAIASMAAAAAAVATGGSRSATSSPPLTIKEDSLAESPAAPVAGTAAPIATGGGSTGKPLIGRAGLAPENYHFTESNDGQFVCKICDAVFNQVALLRKHALAHTEEKPFHCDICDRSFNRVDYLKEHFKSKRHLQLVAEAAAGGDSLPAPIGSGRADEEEDDSTMEEGITSTKRSKMVESKYNAKQASIEEVGHAAMTNGEGARSVDVKGNVSSNSSSSSSSGSSSSRSSSSSRSSSINSNRNNTSVTSNPSPVKQREVGETRSVLGEFHRSDYERTSDGRYKCNQCDKTFVTAVTLKMHIRLHTGEKPYKCDKCDKAFIRSDYLKTHEKCHRQESFLSMLSLKTSKEPSTASEAGDSDADGEPGEGQRHHRGGSAVNGGSETAGGQPTKVEIKDEDTEGEEDGVEEEEDEEEEDGEEEAESEESEDEQVIEVMVKEESCSDSEEDDEDGENEEEDEEEDENNEDGEDAGQHSPFDAANNSTNRIAPSTMIASQHPRKEKGSSGKRRNRPKHSVSSNRAFASAAAAAATSGGDSSNNGFDHEDDSTSQTSGQQYGSGAGEFMSNGQKGKHRCPMCDKLFAWPKSLKIHLRTHTGEKPYRCDVCGKCFGRSDSLRGHKRTHTDDKLIQCHLCDVSCTTATELVQHQYAAHGLQPLES

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00103814;
90% Identity
-
80% Identity
-