Asin004020.1
Basic Information
- Insect
- Anopheles sinensis
- Gene Symbol
- -
- Assembly
- GCA_000441895.2
- Location
- KE524948.1:909108-915274[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.55 39 4.8 0.6 3 23 334 356 332 356 0.91 2 11 7.1 5e+02 1.3 3.6 3 22 511 530 509 533 0.91 3 11 0.00099 0.07 13.4 0.6 2 21 555 574 554 575 0.95 4 11 0.2 14 6.2 0.4 1 23 595 618 595 618 0.92 5 11 0.059 4.2 7.8 2.4 1 23 623 647 623 647 0.93 6 11 0.46 33 5.0 0.2 2 23 664 686 663 686 0.93 7 11 0.0019 0.14 12.5 0.1 1 21 691 711 691 712 0.96 8 11 0.45 32 5.1 0.3 2 19 961 978 960 982 0.82 9 11 0.0031 0.22 11.8 1.6 2 23 1014 1034 1013 1034 0.92 10 11 9.7e-06 0.00069 19.7 0.5 1 23 1040 1063 1040 1064 0.93 11 11 0.14 9.8 6.7 0.5 2 12 1117 1127 1116 1128 0.89
Sequence Information
- Coding Sequence
- ATGCTACACGAGGACGACAGCGAGCTGGATGACACACATCTCTGCATTAAGTGTGGCAGCACTGTGGTGGGAATTGAAAATTACATTAAACACCGCAAGGTAAGCTGCACCGGCGCCGGCGGCCAACCGAAGTCCGTCCAGCACGGACGCGGGCCCACGGATGAGGATGATGAAGCTCCCGGCGGTGGAAGTGGCACTGGCCCCGAGCCGATTGGCAACACCGATCAGCCAACGGTGGAACTGCGCGCCGTCAGTACAACACCGTCGAGCAGCGGACCAACGTCGGCATCCTTTGGGACACCGTTTGACTTTGGCGGAACGATCAAGGAACCGGAGCGGCACAAGAAAGTGCCGAGTTATGACTATCACAACTACGAGCTGGATGTGACCCCGGCCCATCACGAGGACCACAACCGGTCGGACGGTGCGAAAGCGCCCGACTTCAAGAACGAGGAAAACTTCGATTACGACCTCGGAGCGGATATGTTTTTTTGGTCGCTCGAGCTGCAGAGCATCATCAAGCACAAGTCGGGAGGAAACGTTGGCCCGACGGCGACGGCCACGATGGCTGGCGCTGGACCGAGCCCGAGTGGAACTGTCAGCGATATCAGTGGGCACAAAAAGGTAGAGCTGTATCCGATATTCCACCAGGAGTCGCCCGACCCGTCCGATGACGATAGTGAACCGGTGGGGCCGGTAGATGAGGACGAGTACGATGCACCACCCCGCACGCACACCGGTGGCAAGTGGAAGCCGGAGAATCGACCCTCACCGAATGCGTTGCAGCGTTCGACGCAATGGCGCCACTGGACACCGCCGGAACCGGTCGAGAAATCACTCGACACGAGGGAGGAGGACGAACTGGACAGCTTCAAGAGCTTTTCGCCACCGCCGGGACACACCCGGGGCAAGTGGGTGCCCGGGTCGAAGATCACACGGCTCGAGTACAAACCCGTCCATGAACCGATGGCCCGGAGTAGCTACGAGGATAGCTTCTGGTGCAGCATATGCAATCGGCGGTTGGCGTCGCGGTTCGTGTACGTGCGACATCTTAAGTCGAACCTCCATCTGAAGCGGGCCCAGGAGGAAAGCGAACTCGAACGTGCCGTGCGGCCACTGTACGCGAATGAACTTTCAGGCCGGCTGGCGAAACCCGAACCCTCTGGGAGTTCCTCAGGGCGGGTTAATCTGGAAGAACCAGCTCCTGAGGTTTGCACACCGAACGAATCACCGGGAAAGGGGAAAAGAAAGCGTAAATGCTACTACACGAAGTGCACGGTGTGTAAAACGCGACTACCAACACACCTGCTCGGAAAGCACCTGATCTCCCGGTACCATTACCGTCGGATGCTGAACCATCCGACCCAATGCTTCGATGTGGTGCTTCGGAACATGTATCGCATCGTGCGGGAATCTCCATTCCAGTGTGCGCCTTGTAAATTCTACGCCAACAGCGAGCCACACTTCATGGCACACTGGAACTCGACCGAACACGAAGCGCGTGTAGCGTCCCCGAATGGGAAGTTCTGGTGTAGCTTCTGTAAGTTCGAGTGCGAGAGCAACTTCCATATGACGGAGCATCTGCGTGGAGCGAATCATCGTGAGGTGATCGCCGTCATCAACCGCTCCGTACCGATCATCATACGCAAGATCACGCGCATCCGGTGCGACTCCTGCGAGGAGGAGTTCCGTTACAATGCGGAACTACGCCGCCATCAGCGTCACTGTACCGAGGCCAGCTTGGAAACGATCGAGGAGGTGCGCACTCGTGTTCAAAACACTTTCCTTTGTGAGCTATGTAACTCGACATTTCCCAACCGAATCCGACTCCTCCAACATGGCCAGAAGCTACACCGACTGGCGCACTATTACTGTTCCATTTGTGAGTGCTCGTTTGAAACGGCTCAGGAATCGGCGAGACATCGGCGAACCTCGCGCCATAAGGTTTTGTCCGCCAGGAGCAGAAAAAAGACCAGTTTGGTGAAGAAAAGTTGTCCCGTCTGTAAGGAGGAACTGGCGGACGTGCTCGAACTGAAGCAACACATCGCCAATTGCCATCCAGAGGTGAAATATAGCTGCCCGCGGTGCGGCGAGTGTTTCGTCCTGGCGCAGGAACTGGGCAGACACGTACGTGACAAAAATTGTACATTTTTCAACCCCTCGCCATCGTTGGCCTCGCCGGAGGATGGACCGGAGATGCCGTCAACGTCGCTTCCGGGGCCACTCGTAGCGATGGATTCCGGTAGCCCGGCTTCGTCGCCGGGTCCGTCTGCGACTCATCAGCGTCCACTTCTGGCCGTGGGCTCGTCGCAAACTTCGCCGTCGTCGTCGTCATCAGCAACCCGGTCGCATCTTCCGGGCACAAATTCAATTATCTCGAATGATTCAATTAAAGTAAATATGAATGATCGTAAACTAGGCAAGGAGTCACAGCTGTACTCGTCCAGTGGCGTGGATCCGGGCCAGGAGTCGATTGCGGGATCCGCATCGGCCCGAGGTGACAACGCGTCCGTACCGGGAGTGCCCCGGCAGGACACAGCTGATGGGCCTGCGAAAGTTGATATGATGGAAAATTACTCACCCAGCCCCGTCCCGGCACCCGTCGCCCATCCACCGTCCCCCGTCCCAGCGTATGGAATTAAATTGGACTCATCTGCGCCGGCCACCGCCACCCCCGGCCGGATCACCGCACCCCCGGGGTGCGAATCATCGACGGCGGTATCAAGTTCGGATTGCGATAATATTGTCGCCGTGCGCTCCGACCCGCAGGCGTCAGCAGAAATCTTTTTCGCACTGGCTAATAATGCGTCCGAGAATAATACTGTTTACGTTGATGAAATTGTTGGCACCATCGGCGAGGACGGTTCGGCCGTTTGCTGGCAGTGTAAAATATGCCCATTCAGCACGTCATCGAAGGCCGAATTTCTGTTTCACGAAATTTTGCACTCATCAAAGTTGGATGACAAAGCAAAGTCGTCCCAATCGGACCCTCCGGACGAAGCTGGCCGTCCCCGGCCGAGCCGACCCCGCCCGAAGCTCACTTGCCCCCTGTGTGGGAAAGCGTTCTCGAAGGCGTCCCTCCGTTGCCACCTGCGCCAGCACACCGACGAGCGGCTCTTCCCCTGTCCGCTCTGTCCGATGGCTTTCACGCGGAAGGCCAATCTCAAAAATCACACCGATAACATTCACCACCAGCGGAAATCGGCGGCGAGTGCGACGGTAACAAGTGGAGAGATTGCCGAGAGAGGGCCCCACACTCCAGCACCGGTGGAAAGTCCATCCGACCTCGACAGTAGTACCAGCACCACCACCACCACCACCGACCAACCCCAACCAAAGCAGGGATCCGTTTGTACCACTTGCGGGAAAACGTTCGCCAATCGGTGA
- Protein Sequence
- MLHEDDSELDDTHLCIKCGSTVVGIENYIKHRKVSCTGAGGQPKSVQHGRGPTDEDDEAPGGGSGTGPEPIGNTDQPTVELRAVSTTPSSSGPTSASFGTPFDFGGTIKEPERHKKVPSYDYHNYELDVTPAHHEDHNRSDGAKAPDFKNEENFDYDLGADMFFWSLELQSIIKHKSGGNVGPTATATMAGAGPSPSGTVSDISGHKKVELYPIFHQESPDPSDDDSEPVGPVDEDEYDAPPRTHTGGKWKPENRPSPNALQRSTQWRHWTPPEPVEKSLDTREEDELDSFKSFSPPPGHTRGKWVPGSKITRLEYKPVHEPMARSSYEDSFWCSICNRRLASRFVYVRHLKSNLHLKRAQEESELERAVRPLYANELSGRLAKPEPSGSSSGRVNLEEPAPEVCTPNESPGKGKRKRKCYYTKCTVCKTRLPTHLLGKHLISRYHYRRMLNHPTQCFDVVLRNMYRIVRESPFQCAPCKFYANSEPHFMAHWNSTEHEARVASPNGKFWCSFCKFECESNFHMTEHLRGANHREVIAVINRSVPIIIRKITRIRCDSCEEEFRYNAELRRHQRHCTEASLETIEEVRTRVQNTFLCELCNSTFPNRIRLLQHGQKLHRLAHYYCSICECSFETAQESARHRRTSRHKVLSARSRKKTSLVKKSCPVCKEELADVLELKQHIANCHPEVKYSCPRCGECFVLAQELGRHVRDKNCTFFNPSPSLASPEDGPEMPSTSLPGPLVAMDSGSPASSPGPSATHQRPLLAVGSSQTSPSSSSSATRSHLPGTNSIISNDSIKVNMNDRKLGKESQLYSSSGVDPGQESIAGSASARGDNASVPGVPRQDTADGPAKVDMMENYSPSPVPAPVAHPPSPVPAYGIKLDSSAPATATPGRITAPPGCESSTAVSSSDCDNIVAVRSDPQASAEIFFALANNASENNTVYVDEIVGTIGEDGSAVCWQCKICPFSTSSKAEFLFHEILHSSKLDDKAKSSQSDPPDEAGRPRPSRPRPKLTCPLCGKAFSKASLRCHLRQHTDERLFPCPLCPMAFTRKANLKNHTDNIHHQRKSAASATVTSGEIAERGPHTPAPVESPSDLDSSTSTTTTTTDQPQPKQGSVCTTCGKTFANR
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00096690; iTF_00109455;
- 90% Identity
- -
- 80% Identity
- -