Asin012349.1
Basic Information
- Insect
- Anopheles sinensis
- Gene Symbol
- RREB1
- Assembly
- GCA_000441895.2
- Location
- KE524867.1:658829-665913[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.0059 0.42 11.0 4.5 2 21 64 83 64 84 0.94 2 10 7.1 5e+02 1.3 2.3 1 19 129 147 129 148 0.82 3 10 0.0038 0.27 11.6 0.1 1 23 413 435 413 435 0.98 4 10 1.7e-06 0.00012 22.1 0.6 1 23 444 466 444 466 0.99 5 10 0.0014 0.098 13.0 2.3 1 23 472 495 472 495 0.97 6 10 0.0008 0.057 13.7 2.1 1 23 912 935 912 935 0.95 7 10 7.3e-05 0.0052 17.0 0.3 2 23 1405 1426 1404 1426 0.97 8 10 0.37 26 5.3 5.4 1 23 1432 1455 1432 1455 0.96 9 10 1.8 1.3e+02 3.1 1.8 1 23 1692 1715 1692 1715 0.92 10 10 0.01 0.72 10.2 0.6 3 23 1773 1793 1771 1793 0.95
Sequence Information
- Coding Sequence
- ATGTCGGCTGCTGTCGGAGGACGTCAGCATCAACCGCGGAAGGTGCGCACGATCAATAACAACACGCTAGTGGAGGGCGAGAGCGAGGGCGGCCAGCGGTTCTGCTGCCCGGTGTGCGACCGGAACGACTTTCCCGGCATGCTACAGCTCGAGCAGCACCTTGACCAAGAGCACCAGACTATACCAGCCAAGTGCCGGCACTGCGACTACGTGTTCTCCACCCACAAGGCGCTGAACGCGCACCGCTGCAGCAACAACAACTACCAGAACATCACGCCCGGCTTCCGCGATCTCACCTTCGTCGACTTCTCCAGCGAGAAGTTTCCGCTGATCGCGAAGAACCTGTGCGAGCGCAGCATCCGAACGCCGGTGACGACGCCCAAATACGAGTGTCCGCACTGCTACTTCGCCTTCCCGTGCTCCAAGACGCTGCTGATGCACTCGGCCGGGTGCCGGGTGGCGGGCGCCAAGCGTCGCAAGCGTTCCCTCAGCGACTCGGAGGCGTCGTCGGGATTGGACGCGGACGATCGGGTGTCGGAGGACGCGGGCTCCTCCTCGGAAGCCGGGCGTCGCCGACCACCCACTGGCGATGACCATCCGTCCTCGGCCGCCGAGCAACAGCGAGGGCAGCAGCAGGAGCATCAGCTTTCGGAGATGCGTTCCACCGCCGCACCGTTGCGGCGGGAGGATTTCTTTGCCAATCTGGACCTGCAGAACCGATCGGTGGGAACTTTGTCGGAGGCACCGACTACACCATCGTCGCTGGACAAGTCATTCCCGTCGCCGGTGACGCCGTTGCAGGCAGTGAAGCAGGAGCCGCTTGGCTCTCCCACGTACGGCGGCGGCGGATCTCTATACTATACACCGACGGGCGGCGGCGGCATGCTGGGCACGACCACGACGTCGACTAGCTCCTCGTCCTCGCTGTACAGCAATTATCATCACCACCACCACCACTACAGCACGCAACAGCACCACCAAGACGGCGGCAAGGACCTTGCCGACATTCAGTCGATCATCAATGTAGCTTCCTCGGGCGGACTGTTCGGGCGGCAGCCACTGGACGGCGGTGGCAGCAACAGCGGAGGAGGCAGCCAGACGCCCCTCTCCGGCATGATGATCGCCGATACGAAAGAGCTGGACATGTACGCGCACTCGACCGGTTCCCGAGACGAGCCGGAGGAAGCGCAGGACGCGTTCACCGTCGAGTTTCGGCGCATGAAGCTGCGGGGCCAGTTCCCGTGCCGCATCTGCACGGCCGTCTTTCCGAACCTGCGGGCGCTCAAGGGCCACAACCGGACGCACGTGACGGCAGCCGGCCCGGGGCCGTACCAGTGCAACATGTGCACGTATGTCGTCAGCGACAAGGCGACGCTGATACGCCATATGCGCACGCACAACGGTGACCGGCCGTACGAGTGTGCGCTCTGCAACTATGCCTTCACGACTAAGGCCAACTGCGAGCGGCACCTGCGCAACCGACACGGGCGAGTGACACGCGATGAGGTGAAGCGCGCCATCATCTACCACCCGTCGGAGGACTCTTCCTGTGACGATCCGATGAAGAAGCTGCAGCTGTTCAACACGCCACCGGCCGACGGCCACTACGTGCTGGGCGTACCGTCGTCGGGGGCCGGCTGCTACGACGATTCGCCGCAGCAGCGCAGCAGCACACCGCTCAAGGACATGCTCCTGCCATCGCTTCCCCTCGGCTACACGACGGCGGGCACCGGCGGCCAAAACAGCAACTCCCTGCTCGACAACACCGCCCTGTTCCTGCAGACACCGCCCCGCGGTGGCGGTGGAGCGCTCGATGTGACGGCGGCGGCCGCATCCGCCGCGGTGGCGGCTAAGATTCAGGTCAAGAGTCTGGAGAAACTCAACCAGCTGACCCCGCCGCAGGAGGACGACCACGATGACGAGGATGATGATGAACACGAAAGAGGGATAGCACCACCACTGCATCATCATCATCATCGCCGCCTCATGCACCAGCGCCCCACCACGTTCAATCGGCCGTCGTCGAAGCGGGGCGACATACCGGCAGCGAAGAAAGTGGCGCTGGAGAATGAGGACCACGACGGTGAGGAAGATGAGCGGGAGCAGGAGCAGGAAGAGGAGGAGGAAGCGGTGGCCCTCGTTGTCCATCGCCCGATCGATCTGAGTATGGACGCGCTGGATCTCAGCAAGAAGTCCCGCCCGTCGCAGTCTGGCGGTGTTCAACCGCCTGCGAATGGAGAAGTGCAACGGCAGCGACAAAGCGCCACCAATAATCAGGACGACGAAGTGGGGAGACGGACGGTGCTGGAAAGCGGCGGCATCGGTACAGAGCAGAAGCCTCTAGCCGCACCACCACCACCAACAGCACCGTCGTCTTCTGCCGCCGACTTGCCGCAATTCCCGCTACTGAACGACGAAGCATTCGTTGGTGCGGGCGGCGCCAGCAAGAGCTCAGCAAACCTCTTCCAGCTGCAGCTGTACCAGCTATACAACCAGCTGCATTCGGCGCTTCCACCGATGCCACCGGGAGCACCCTACCCGCTGCAGCTGGTGGCCCCCTTCCTGCAGAACCCGATGCTGGCCGGGTCGGCCGCGGCCATGTTTGGCGACCTGCTCGCGGTGAACGGCGGAAAGCTGCTCATGGGAGGCGAACACGGCCCATCGTCAACAGTAGCCACACCGCCAAAGACTCTGACACCGTCCTCACTGTCCCCCATGTCGACACCGCGCCCGTTCGCCTGCGAACATTGTTCGGCCCGGTTTACTCTCCGCTCGAACATGGAGCGCCACATTAAGCAGCAGCATCCGCAGTTCTGGTCCCAGCGCCAGCGTGGTGGCCATCATCTGATGCGTCGTGGAGGCGCCAGTGGAGGAGGAGGAGGAAGTGGAGCATCGCCGGGTGGAGGCATAGTTTCGTTGGCCAACACGTCGCTCGCCGCCGCGCTCCAGGGAGCCTTCGGGGCCATCTCCGAGCAGGTTAAATACGCAATCTTGGCTCAGCAGTCCGGAAAAGGAGGGGCTGCTGGGGCCGTTTCCAGCCAGATGAACCCGTTGCTGCACAACATGATTGTCGGAGGAGGTGGTGGAGGTGCTGGTGCTGGTGCTGGCCAGTGGGGAGGACTTCACCACCATCCACAGCAGCACCGCAGCAGCTCGTCGATGGACTCTCCCCATCATCAGTACGGGTCGGCGCGTGCACCGAGCATTCCAGCGGTGCCACCGCAGGGCGATGGCAGACGCCGGCCGATTCACGATGTAACCACCACCGAAGACGAGGATGGTGTCGAGCTAGACGGCAGGGAGGATCAACACATGCAGCCATCGCTTCACTACGGCGCAGGTACGCCTCTCATCGGCCAACGGCATCGTCGGCGTCGGCGTCGGCTGCAGCAAGACTTTCATGACGAACAGGAGATGTCACACCACAACCTGCGCCACCATCTGTCATACGACTACGACGAAGAAGCAACCGAGCTGGTGAAGAACCATCTCGCTGATGCGCCCGACGATCAGCAGGAGCAGCAGCGCCACCACCACGATGATGATGGTGATGAGGAGGAGAGCGGCTTGGAGCAGCACCAGCGCAAAGGCGAAGGTGCGGTCAGCAGCAACTACGACGACGAGGAGGAAGAGGAAGAGGACGCCCAGCTTGTCATCGACGAAGAAGGCTGTGACTCGACACAACACACTCCGAACGGAACCGGTCCCATCGAACCTGCCGTCGACCATAGCCCCAATCGCATTCTAAAGCAACAGCTCGAGCAGAAACAACATCATCGTAGTGGGGACAGCGAAAAGCTGCAGCGGCAGGAGAAGTCGGCAGGAGCGCACGAGCAGCCAACACCGTCATCCATGAACAAGCCCAAACGGCTCCACAGTGGTGGTGGTGGGTCGAGGAAAAGCTCCTCCGGAAGCGGTAGGCACAACGAAAGCAGCGCTAGTGACGAAAGTGGAAGCAACAACGATCTCGTGTCGGTTGCGAAGCTGGTCGACAATGCAACCAACAACCCGGCGCTCGAAAGCTACTTTAGCAGGCCTGAGGTGCAGGTGGTTCCGCTGGCGCAGGATCACAGCGACGAGGAGGGTCTGGTCGCGTCCGGGTCCGCTTCGGAGAGCAACAACTCCGGCACCGACGACCCGAATCCGTCGGCGGTGGCGGGCGAGCAGCAGGAGAAGAAGAAATCCGCCTACAGCTTGGCCCCGAACCGCGTCAGCTGTCCGTACTGCCAGCGTATGTTCCCGTGGTCGAGCTCGCTGCGGCGCCACATTCTCACGCACACCGGTCAGAAGCCGTTCAAGTGCTCCCAGTGCACGTTGCTCTTCACCACCAAGTCGAACTGTGATCGGCATCTGCTGCGCAAGCATGGTGACGTCCAGACGGCCACCTCTATCCCGGTGCCGATCGACGACCTGCTCGATCCGAAGCCGGAACCGATTCCGGTCGCGGTAGCAGAGGCGATGAGCAAGAAGATTGCCGACAAGAGTGCCTCCGCCACCGGTAGGCGACAATCAGTGGCGTCTACAGGACGGTCACCACCATCGTCAAACAAGCAGTCGGCTGACGTTGCTCTCCAGTCCGACTTGACCGGTGGGTCGACCACAAAGCATGCCAAAGCCAAAGACGAGCTGACGGAGGAGCAAGTCGTCACGCCGGCTGACAAGCAACAGGAAGAGTGCCGTGACGATGCTTCCGACGAGCAAGTGGGAGCTGGCGGTGAGTCGGACGGAGATCAGAAGCCGTCACCCAACCGCACTATGCCGCAGCAGTGGAGTGCTTCTTCTGTCACTGGAGGTGTGACGGCGACCAACCTAACCGACGAGTCGGACGTAGAAGAGGAACGCTTCAAGAGAAAGGAAGGCGACGAAGACGACGGCGATGACGATGGCGAGAATAAGGATGAAGGTGATGGTCTAGGCCGAGACAGACGCGGAGTGCGCAGAAAGGCTACCCGGCACACCGATAACAACGATGTGGGCGAGGAAGACCAAGAGATGGAAGCGGACGCGGACAATGACGACGAGGACGACGACGAGGAGGAAGAGGAGCATGCGGCGAACCATCCCGATCTGCCGTACAAGTGCCATCTGTGTGATGTGTCCGCCGCCGACCGGATGAGCTGTCTGGAGCACATGAAACAGGTGCACGCACACGACGAGGCGCAGACCGCGTCCCCGGACGACGACGAGAGCTGCAACAACGAGCCGCCGGCGACCCCAGCGGCCCCCAAGCACAACAACAACAATCCCAGCATCAGTAACAATAATAATAACAACAATGGTGGCAAGTATCCCGACTATGCCAATCGGAAGGTTATCTGCGCATTCTGTTTGCGTCGCTTCTGGTCGACGGAAGACCTGAGACGACATATGCGCACGCACTCCGGCGAGCGGCCGTTCCAGTGCGATATCTGCAGCCGCCGCGAGGACGACGAGTACTACGAGTACTGCCAAAACCGCATCACAACGGAGTATCGCCGGTCGTCCAGCAGTTCAGCGGTTGCTTCTACGCCTCCGGCCCAACCCTTCCGTCACCGGAACCAGTTCACCAGCAAAGTTAACAACAACAACAAAACCAAAGGCGACGACGACAGCGAAAACGATCCCGCCAACAACGTTGCGGAGATCCCAGCGGCGGCACTCCGCCATGCTGGGAATCGCTACTATCACCTCTACAGCAACATCAAAAGCCAGTCGGCAGGCGGCGGCGGCGGCGGCGGTGATGGCGCCAACGTTGGCCAGCAGCATCAATCGGAGCTGATCGGTGATCTGCTCGGCATCAGCGACCAGGGTATCCTCAGCCGGGTGCTTCTGTCATCTGCCACCGAGGCAGCTAAACTGCTCGGCGTCGACAAGTGA
- Protein Sequence
- MSAAVGGRQHQPRKVRTINNNTLVEGESEGGQRFCCPVCDRNDFPGMLQLEQHLDQEHQTIPAKCRHCDYVFSTHKALNAHRCSNNNYQNITPGFRDLTFVDFSSEKFPLIAKNLCERSIRTPVTTPKYECPHCYFAFPCSKTLLMHSAGCRVAGAKRRKRSLSDSEASSGLDADDRVSEDAGSSSEAGRRRPPTGDDHPSSAAEQQRGQQQEHQLSEMRSTAAPLRREDFFANLDLQNRSVGTLSEAPTTPSSLDKSFPSPVTPLQAVKQEPLGSPTYGGGGSLYYTPTGGGGMLGTTTTSTSSSSSLYSNYHHHHHHYSTQQHHQDGGKDLADIQSIINVASSGGLFGRQPLDGGGSNSGGGSQTPLSGMMIADTKELDMYAHSTGSRDEPEEAQDAFTVEFRRMKLRGQFPCRICTAVFPNLRALKGHNRTHVTAAGPGPYQCNMCTYVVSDKATLIRHMRTHNGDRPYECALCNYAFTTKANCERHLRNRHGRVTRDEVKRAIIYHPSEDSSCDDPMKKLQLFNTPPADGHYVLGVPSSGAGCYDDSPQQRSSTPLKDMLLPSLPLGYTTAGTGGQNSNSLLDNTALFLQTPPRGGGGALDVTAAAASAAVAAKIQVKSLEKLNQLTPPQEDDHDDEDDDEHERGIAPPLHHHHHRRLMHQRPTTFNRPSSKRGDIPAAKKVALENEDHDGEEDEREQEQEEEEEAVALVVHRPIDLSMDALDLSKKSRPSQSGGVQPPANGEVQRQRQSATNNQDDEVGRRTVLESGGIGTEQKPLAAPPPPTAPSSSAADLPQFPLLNDEAFVGAGGASKSSANLFQLQLYQLYNQLHSALPPMPPGAPYPLQLVAPFLQNPMLAGSAAAMFGDLLAVNGGKLLMGGEHGPSSTVATPPKTLTPSSLSPMSTPRPFACEHCSARFTLRSNMERHIKQQHPQFWSQRQRGGHHLMRRGGASGGGGGSGASPGGGIVSLANTSLAAALQGAFGAISEQVKYAILAQQSGKGGAAGAVSSQMNPLLHNMIVGGGGGGAGAGAGQWGGLHHHPQQHRSSSSMDSPHHQYGSARAPSIPAVPPQGDGRRRPIHDVTTTEDEDGVELDGREDQHMQPSLHYGAGTPLIGQRHRRRRRRLQQDFHDEQEMSHHNLRHHLSYDYDEEATELVKNHLADAPDDQQEQQRHHHDDDGDEEESGLEQHQRKGEGAVSSNYDDEEEEEEDAQLVIDEEGCDSTQHTPNGTGPIEPAVDHSPNRILKQQLEQKQHHRSGDSEKLQRQEKSAGAHEQPTPSSMNKPKRLHSGGGGSRKSSSGSGRHNESSASDESGSNNDLVSVAKLVDNATNNPALESYFSRPEVQVVPLAQDHSDEEGLVASGSASESNNSGTDDPNPSAVAGEQQEKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSQCTLLFTTKSNCDRHLLRKHGDVQTATSIPVPIDDLLDPKPEPIPVAVAEAMSKKIADKSASATGRRQSVASTGRSPPSSNKQSADVALQSDLTGGSTTKHAKAKDELTEEQVVTPADKQQEECRDDASDEQVGAGGESDGDQKPSPNRTMPQQWSASSVTGGVTATNLTDESDVEEERFKRKEGDEDDGDDDGENKDEGDGLGRDRRGVRRKATRHTDNNDVGEEDQEMEADADNDDEDDDEEEEEHAANHPDLPYKCHLCDVSAADRMSCLEHMKQVHAHDEAQTASPDDDESCNNEPPATPAAPKHNNNNPSISNNNNNNNGGKYPDYANRKVICAFCLRRFWSTEDLRRHMRTHSGERPFQCDICSRREDDEYYEYCQNRITTEYRRSSSSSAVASTPPAQPFRHRNQFTSKVNNNNKTKGDDDSENDPANNVAEIPAAALRHAGNRYYHLYSNIKSQSAGGGGGGGDGANVGQQHQSELIGDLLGISDQGILSRVLLSSATEAAKLLGVDK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -