Basic Information

Insect: Anopheles sinensis
Gene Symbol: ZEB2
Assembly: GCA_000441895.2
Location: KE524975.1:511611-513963[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 1.2 86 3.7 1.1 1 23 192 215 192 215 0.91

2 14 0.19 13 6.2 0.1 1 21 230 250 230 251 0.93

3 14 0.039 2.8 8.4 2.3 1 21 257 277 257 278 0.95

4 14 0.019 1.3 9.4 0.8 2 23 348 370 348 370 0.88

5 14 0.0051 0.36 11.2 0.8 2 19 380 397 379 400 0.91

6 14 0.0054 0.38 11.1 1.7 1 22 408 429 408 433 0.93

7 14 0.042 3 8.3 0.6 3 23 470 492 469 492 0.86

8 14 0.00026 0.019 15.2 0.9 1 20 508 527 508 529 0.94

9 14 0.00053 0.038 14.3 0.0 3 23 538 559 537 559 0.95

10 14 1.5e-05 0.0011 19.1 3.0 1 23 566 588 566 588 0.98

11 14 0.074 5.3 7.5 3.9 3 23 596 617 594 617 0.96

12 14 0.38 27 5.3 4.4 1 23 623 645 623 645 0.98

13 14 0.017 1.2 9.5 5.2 1 23 651 675 651 675 0.95

14 14 0.00058 0.041 14.1 0.6 1 23 681 703 681 703 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	1.2	86	3.7	1.1	1	23	192	215	192	215	0.91
2	14	0.19	13	6.2	0.1	1	21	230	250	230	251	0.93
3	14	0.039	2.8	8.4	2.3	1	21	257	277	257	278	0.95
4	14	0.019	1.3	9.4	0.8	2	23	348	370	348	370	0.88
5	14	0.0051	0.36	11.2	0.8	2	19	380	397	379	400	0.91
6	14	0.0054	0.38	11.1	1.7	1	22	408	429	408	433	0.93
7	14	0.042	3	8.3	0.6	3	23	470	492	469	492	0.86
8	14	0.00026	0.019	15.2	0.9	1	20	508	527	508	529	0.94
9	14	0.00053	0.038	14.3	0.0	3	23	538	559	537	559	0.95
10	14	1.5e-05	0.0011	19.1	3.0	1	23	566	588	566	588	0.98
11	14	0.074	5.3	7.5	3.9	3	23	596	617	594	617	0.96
12	14	0.38	27	5.3	4.4	1	23	623	645	623	645	0.98
13	14	0.017	1.2	9.5	5.2	1	23	651	675	651	675	0.95
14	14	0.00058	0.041	14.1	0.6	1	23	681	703	681	703	0.97

Sequence Information

Coding Sequence: ATGATTTCATCAGAAAAATCGTCGAAAAGAATGGCGAAACGTAGAGTTAATTGTTTCTTGTGTGATCAATCGTGTTCGGTTTCGAATGTGATAAATTGGAGTGCAAAATTTAACAAAGATCCTCATCGTACGTTAGCAGATGCTGTTCTTGATTTTGCAAACATTGAGGGTAATGCGTCGATTTTAGGGGCCAACGAGGTTGTCTGCATTAACGTTTGCTACCAGCGGCTGATGGAAGGATTAGAATTTCAAGATGTGATAAGGCACGTACTTAAAAGTATGCTTTCCCGAGTCGAAAAGGCTTGTTCCGATAGCCACGAAGCTCAAGATGCTTGCGAAGAAACGACAGATCAATCCGCATACATTGAGATGGAAGATGTAATGGATTGCGGAAACAGTAGCATCGAGCAGTGTCCAGAACAAATCGATTGCTTTGATGTACAAGAAGAAACGACTGAACCGGGTACATTGAGTCAGCAAGAAGACGATGGTAGACCTTTCCTCCAACCAACACCAAAGTACATTGCCACGCACATGCAGTTCCAAAACTTCGAGTACTTTGAGTTAAACGGTCACAGATGTTGCGGTTGTAGCTTCGTTGCCGAAACGATGAGTGAACTGTCCCAACATGCCAACGATGCTCATTCCTCTCAGTATTCCCCCGATGGGTTATCTGCCGATCGCACACACGTTTGTTCGATTTGTAGGTCAGCCTTTGAATCCGCAGAAACACTAGATTTACACAGGCAAAACCAGTCAAGAGAAATATTCGTCTGTAAATGCTGTACATTAGCGTTCAGTACAAAGCAGCGCTTGATGAAGCACATGATGCAGTATTCATTTGACGAAAATGATGAAACGGTGCTGATCGATGGGCGTAGTTCTTCTGCGGATCAAGAGAACTATTTGGAAGAAGTGCTGTACGCCGAAGATACATTGAAAAGCGACAAAACGCCCGGGAATGAACCGCTTCTTGAGGATCAATACGTAACGCACGTAGAAGATTACGACGACTATCGAATCCTGCATACCGAGGCGGAGCGATGTTGCAGCTGTGGCAAGTTTTTCGCCAACTACGACCAAATGCTCGCCCATGCCATAGCAACGCACGAACACGGGGATATTGCTAGCGATTGGAGTTGTCGTGCTTGCGGAGAGACGTTCCAATCGAAGCGAAACCTAAAGCATCACAATGCTACCAATAGTAGTTTCAAGAAAATCTTCCACTGCAAGCTTTGCAACGTTTCGTACGTACGGATCCATCTGCTCGCGCGCCATATTCTGACCTCGTTGAAGCATCGTTCGAATGGAACGGGTAATATACTGGAGAAACGTAACGACGAGCAGCTTGCCGCCATCCTTCGGCAAAAGTCCTACAACGCTAGCAAGTTCTCCGGTTTCGGGTGTTGCTTCGTTCGCTGCGGCGCCACGTTCGAGGACGAAAAGCAACTGCAGAGTCACGTGGAAGAAATGCACGCCGTCCGTAGACGGATTCACGCCAGCGAGCGTACCTCGGACCAGCACGTGTGCGACGTATGCCAGCTGAGCTTTTCGAAGGAGCAAAACCTGCAGCGGCACCGGTATAGCTGGCAGATGCGAAAGGTCAACATATGCAGCTACTGTGGAAAGGGTTTCCCGAATCAGGCGGTCCTGTGGGAGCACGAACAGGTGGAGCACACCGACATGAGCCCACAGTTTGAGTGCGAACATTGCGGGAAACGGTTCAAGAAAAAGTCACTGATCAAACTGCATCTCGTAACGCACCAGGAAGTGCGGCGATATGGCTGTGACCAGTGTGGCTCGCGGTTCCACTTCGGGCATCAGCTGAAGAAGCACCAAAACTCGGTCCATGCAACCGAACTGCCGTACGAGTGCAAGTACTGCGAACACAAGATGCCCAGCAAGCAGCGGTACGATCAGCACATGCGAAAGCACACCGGAGAGCGTCCGTTCGAGTGTCGGCACAAGTGCGGGCGGACCTTTTCCCACACAACCGACCGGCGCCGGCACGAAATGTCGGCCCATACCGGGGAAAAGCCACACAAATGTCTGGCATGCGGTATAGCGTACGTGCGGCGAAGAGAACTGCAGTTGCACATTCAGAAGCATCCGGATCATAATGTCGAAGCCAGTGTGCAGGAAGTTGTAACAACAAACGACGACTTTTTAACGGCAGGATAA
Protein Sequence: MISSEKSSKRMAKRRVNCFLCDQSCSVSNVINWSAKFNKDPHRTLADAVLDFANIEGNASILGANEVVCINVCYQRLMEGLEFQDVIRHVLKSMLSRVEKACSDSHEAQDACEETTDQSAYIEMEDVMDCGNSSIEQCPEQIDCFDVQEETTEPGTLSQQEDDGRPFLQPTPKYIATHMQFQNFEYFELNGHRCCGCSFVAETMSELSQHANDAHSSQYSPDGLSADRTHVCSICRSAFESAETLDLHRQNQSREIFVCKCCTLAFSTKQRLMKHMMQYSFDENDETVLIDGRSSSADQENYLEEVLYAEDTLKSDKTPGNEPLLEDQYVTHVEDYDDYRILHTEAERCCSCGKFFANYDQMLAHAIATHEHGDIASDWSCRACGETFQSKRNLKHHNATNSSFKKIFHCKLCNVSYVRIHLLARHILTSLKHRSNGTGNILEKRNDEQLAAILRQKSYNASKFSGFGCCFVRCGATFEDEKQLQSHVEEMHAVRRRIHASERTSDQHVCDVCQLSFSKEQNLQRHRYSWQMRKVNICSYCGKGFPNQAVLWEHEQVEHTDMSPQFECEHCGKRFKKKSLIKLHLVTHQEVRRYGCDQCGSRFHFGHQLKKHQNSVHATELPYECKYCEHKMPSKQRYDQHMRKHTGERPFECRHKCGRTFSHTTDRRRHEMSAHTGEKPHKCLACGIAYVRRRELQLHIQKHPDHNVEASVQEVVTTNDDFLTAG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -