Basic Information

Insect: Anopheles sinensis
Gene Symbol: Prdm1
Assembly: GCA_000441895.2
Location: KE525352.1:1978190-2015037[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 1.4e-07 9.7e-06 25.6 0.8 1 23 817 839 817 839 0.99

2 5 7e-06 0.0005 20.2 5.1 1 23 845 867 845 867 0.98

3 5 1.5e-06 0.0001 22.3 4.3 1 23 873 895 873 895 0.98

4 5 0.00049 0.035 14.4 2.4 1 23 901 923 901 923 0.97

5 5 8.3e-05 0.0059 16.8 0.1 1 22 929 950 929 950 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	1.4e-07	9.7e-06	25.6	0.8	1	23	817	839	817	839	0.99
2	5	7e-06	0.0005	20.2	5.1	1	23	845	867	845	867	0.98
3	5	1.5e-06	0.0001	22.3	4.3	1	23	873	895	873	895	0.98
4	5	0.00049	0.035	14.4	2.4	1	23	901	923	901	923	0.97
5	5	8.3e-05	0.0059	16.8	0.1	1	22	929	950	929	950	0.96

Sequence Information

Coding Sequence: ATGTCTGGAGCGAATCCCCCTCGGAGTGTGACGCCGAACGCGCAGCAGGACTACGATGTTACGCGTATGCGAGAGGAAGACTTCGAGCGGCTGGCCGTCTACATCGTGCCGGATATGCCCTGCGAGAAGGGCGTACCGGGACGGGCGGAGAAAACCCTACCCCGCAGCCTGACGCTTAAGCCCTCGCTCGTCCTTTCAACGCCCACTTCAACGACTGAAGGAGTATGGAGTACAGGCGTCATCCCTCGGGGTACCAGATTTGGACCTTTCGAGGGAGTCCGCACACCGAGCCACCCCAGCGACAAGCAGCTGTGGCGGTACTTCTGGAGGGTGCAGGAATTGCGACACGTCTCCTATGGGAATATCAAGATATTTAAGGACAGTGATTTCTACTACCTGGATGGTTCGGACACGACACAGTCGAACTGGATGAGGTACGTGGCGTCTGCGTATAGTTTCGCGGTGATGAACCTGGTCGCCTGCCAGCACCAGGAACACATCTACTTCTACACGATACGCGACATCATGCCGAACGAGGAGCTGATGGTGTGGTACTGCCGGGACTTTGCCAAACGGCTCGGCTACGACATCGATCCGGAGCGTGCAACCTACTCGATCTGCCGTGAGGAGGTCGTGAAGAAAACGTACAAGCAGCCCGTTCCACCCGAGGTTGCCTACAACCACGTGAAGCACGTAATGGGCCTATACCTGCCAGCGATGGTTCGAAGTACGCCAACGCCCAGTCCATCTCCTCCGGCACCAACCCAAACGGTACTGGTGCCTCCTTCCTCCACGCAAGCCAAGCACCAGCATCAGCCTCATCACAACCACTACCAGCATCAGACGGTTCTGCGGGAACCCCGGGGTCAGGTGGTCAAAGGGGAACCGGTGCGTGACCGTTCCCCGATTCGGATCATGATCCGGGGCGAACAGAGTCCGGTCCGTGCGGAAAGCGCAAAGGAGGAGACGATCGATGCCGATTCTCCAATTTCGCAAACGAAAGAGGCGGCCTACGAGCACCAGCTAACGCCGAACGATGGTTCGGTGCGATCGGATGAAGGCTATCACAGCAACGGATACCACGAGGATGGCTTTACGCCACCGGAGGACTCGAGTGACAGCGAGAGCGAGCACAACTACGTGCTGGACTGCTCGAAGAAAGCGATCGAGCCGAAGGAAACGAGCGTCGGGCATAAGGTGAGCACAAGTGAGCCATCCAGCGACAAGAACGAGTACCGCAAGGTCAAGATGAAGATGCCACTGAAGTACGAGTTCAAGCACAACAGCAAACACTTCAAGGTGGAGCAGGAGCGGGAAGCGGAAACGACTGGTAGCGAGCGGGAGGCGGAAGCGGAAGTGGAAGCGGGAGTCGTCACACCAGCGACCAGCACCGTCATTGTCCTGGACACGACCCCATCTGGCCCGCCGGTTGTAGTCCCTCTTACCAAGAGTTACTACGAGGCGGAACCTTCGACATCTCCTCCGGTGGCACCTTCCTTCATCCGCTATACACCGCCCAGCTCGAGCATCCTTGAGACGATTCTCACCGGAGCAGGAGGTACTGGACGTGTGCCACCGCCGGCCGATGATCCACACCGCCGCCAACCGAACGCTACACCTCCTCCGACATCGCCCACCGAGATGGCGTACTCGTACAAAAAGTCCCAACGCTACGGAACGGCCTGTAGCCCGGACTCGAGTTCCCAGAACCCAGCCGTGGAGCCACCGACACCCCATGCCCCCGCTAGCCCTACTCCACGATCTCAGGTGATACAGGAACCGAAGGAAGCAGACATGGACCACGTGGACCATCACCATCTGCACCATCTCGGTCATCACCACAGCCAGCATCACGTTCTGCATACGCACCACAGCTTCCACGAGGCAGACCCTCGTCCATCCTCGCCGTCACCCTCGCCCCTGGTGTACGCCGGTGAGCACCATCCTCATCATCTTCACCAACACCACCTGCACCCGTACGAGTCCCCAGTGCAGACGAGCTACGGAAGTATTTATCCGACGTCCAACGGAGGAAGTGTGATCAATACCGCATCCAGCTCCACCTATAGCCCACCCCTGAATGGTGGTCACTATGAGAGACTGACGACAACGACGGCGACGACAACGAGTGCGACCTCTGCGAACAGTACTCCACCGCATCATGGAGGTATGCGCTCGACATCCCCGGGAAGTCAACAGCCGGGAGGTTACGTGCAACTGCAGTCCAAGGGTCAGCTCCCGCTGGGACATCCTCTGATGCAACCACTGACTCCTCTGACGACGACGCACCTATCCTCCCCTGGGCGTACCGTTTCGCCACCCAGCAGTCTCAGTCCGGATGGAGGTTCTTACTCACGAAGTGGTAGCCCTATGAGCCCGGGAAGTCCCAACTCTCGCGGGTACCGTAGCCTACCCTATCCTCTGCGTAAGCGCGATGGCAAGATGCACTACGAGTGCAACGTGTGCAGTAAAACGTTCGGGCAGCTATCCAACCTGAAAGTGCACCTTAGGACACACTCCGGTGAGCGGCCGTTCAAGTGCAACGTCTGCACGAAGTCGTTCACGCAGCTAGCGCACCTCCAGAAGCATCATCTGGTGCACACGGGCGAGAAACCGCACCAGTGTGACATCTGCAAGAAGCGATTCTCGTCCACCTCGAACCTGAAGACCCACCTGCGGCTGCACAGTGGCCAGAAGCCGTACGCGTGTGATCTCTGCCCGCAGAAGTTCACCCAGTTCGTGCACCTGAAGTTGCACAAGCGCCTACACACCAACGACCGACCGTACGTGTGCCAGGGCTGTGACAAGAAGTACATCAGTGCGTCCGGACTGCGCACCCACTGGAAGACGACCAGCTGCAAGCCGAACAACCTCGAGGAGGAGCTGGCGATGGCCGCGGCCGCCACATCCGAGTGTCTCGATAAGGATGGTCAGCCAGATGGTGAAGGTGGGCGCGAGTTCTACGATGTGCACCTACCTTCACAACATCCAGCGGGCGATATGTCCCCGGCGCAGCTGCGTCACCACGGATCACCCAACGGCGTACCACCACCTCACCAGCAGCATCATCATCAACAATCGTCCCCAGGTGGACCACCATCTCACCATCCCCACCACCTGTCCGGCCACCATCACCCCGAGCAGGTGATACACAAGGTGTCGGCGGGTAAAATCCACACATCGGCGGGCTCCAACAACAACAACAACAACAACAACAACACCCCGAACAGTACCAACCACAACCTGCCTCCCCACCACCATCTGCACTACGGTGCGGCACATCACGGACCTTCGGCGACGAATGGTACGACGGGGGCACCAACTCCGGCACCCGCTTCGGTCACNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNACGAGCCCACCACGAGCCGACCGAGCGTGATCGAGTCCAGCCAGCCGATGGTGATCGAGTGCACGTAG
Protein Sequence: MSGANPPRSVTPNAQQDYDVTRMREEDFERLAVYIVPDMPCEKGVPGRAEKTLPRSLTLKPSLVLSTPTSTTEGVWSTGVIPRGTRFGPFEGVRTPSHPSDKQLWRYFWRVQELRHVSYGNIKIFKDSDFYYLDGSDTTQSNWMRYVASAYSFAVMNLVACQHQEHIYFYTIRDIMPNEELMVWYCRDFAKRLGYDIDPERATYSICREEVVKKTYKQPVPPEVAYNHVKHVMGLYLPAMVRSTPTPSPSPPAPTQTVLVPPSSTQAKHQHQPHHNHYQHQTVLREPRGQVVKGEPVRDRSPIRIMIRGEQSPVRAESAKEETIDADSPISQTKEAAYEHQLTPNDGSVRSDEGYHSNGYHEDGFTPPEDSSDSESEHNYVLDCSKKAIEPKETSVGHKVSTSEPSSDKNEYRKVKMKMPLKYEFKHNSKHFKVEQEREAETTGSEREAEAEVEAGVVTPATSTVIVLDTTPSGPPVVVPLTKSYYEAEPSTSPPVAPSFIRYTPPSSSILETILTGAGGTGRVPPPADDPHRRQPNATPPPTSPTEMAYSYKKSQRYGTACSPDSSSQNPAVEPPTPHAPASPTPRSQVIQEPKEADMDHVDHHHLHHLGHHHSQHHVLHTHHSFHEADPRPSSPSPSPLVYAGEHHPHHLHQHHLHPYESPVQTSYGSIYPTSNGGSVINTASSSTYSPPLNGGHYERLTTTTATTTSATSANSTPPHHGGMRSTSPGSQQPGGYVQLQSKGQLPLGHPLMQPLTPLTTTHLSSPGRTVSPPSSLSPDGGSYSRSGSPMSPGSPNSRGYRSLPYPLRKRDGKMHYECNVCSKTFGQLSNLKVHLRTHSGERPFKCNVCTKSFTQLAHLQKHHLVHTGEKPHQCDICKKRFSSTSNLKTHLRLHSGQKPYACDLCPQKFTQFVHLKLHKRLHTNDRPYVCQGCDKKYISASGLRTHWKTTSCKPNNLEEELAMAAAATSECLDKDGQPDGEGGREFYDVHLPSQHPAGDMSPAQLRHHGSPNGVPPPHQQHHHQQSSPGGPPSHHPHHLSGHHHPEQVIHKVSAGKIHTSAGSNNNNNNNNNTPNSTNHNLPPHHHLHYGAAHHGPSATNGTTGAPTPAPASVTXXXXXXXXXXXEPTTSRPSVIESSQPMVIECT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00096601; iTF_00109364; iTF_00106040;
90% Identity: iTF_00096601;
80% Identity: -