Basic Information

Insect: Anopheles sinensis
Gene Symbol: L
Assembly: GCA_000441895.2
Location: KE525351.1:388295-406572[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.5 35 4.9 5.7 1 23 3 25 3 25 0.98

2 17 4.1e-06 0.00029 20.9 3.7 1 23 31 53 31 53 0.99

3 17 1.3e-05 0.00089 19.4 0.3 1 23 59 81 59 81 0.98

4 17 3.1 2.2e+02 2.4 0.1 2 23 178 201 177 201 0.83

5 17 0.7 49 4.5 0.0 3 23 257 278 255 278 0.93

6 17 0.17 12 6.3 0.2 1 23 605 627 605 627 0.95

7 17 1.3 93 3.6 0.1 1 23 666 688 666 688 0.90

8 17 0.00027 0.019 15.2 0.2 1 23 733 756 733 756 0.93

9 17 0.038 2.7 8.4 2.1 1 23 763 786 763 786 0.97

10 17 0.0037 0.26 11.6 0.5 1 23 818 841 818 841 0.98

11 17 0.12 8.7 6.8 0.2 1 23 1169 1193 1169 1193 0.94

12 17 0.00053 0.038 14.3 0.2 2 23 1202 1224 1201 1224 0.96

13 17 0.0083 0.59 10.5 0.1 1 23 1231 1253 1231 1253 0.97

14 17 9.6 6.8e+02 0.9 1.2 2 20 1261 1279 1261 1282 0.93

15 17 0.024 1.7 9.0 0.4 2 23 1505 1526 1504 1526 0.95

16 17 0.0077 0.54 10.6 0.0 1 20 1536 1555 1536 1559 0.95

17 17 0.031 2.2 8.7 0.3 1 23 1567 1589 1567 1589 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.5	35	4.9	5.7	1	23	3	25	3	25	0.98
2	17	4.1e-06	0.00029	20.9	3.7	1	23	31	53	31	53	0.99
3	17	1.3e-05	0.00089	19.4	0.3	1	23	59	81	59	81	0.98
4	17	3.1	2.2e+02	2.4	0.1	2	23	178	201	177	201	0.83
5	17	0.7	49	4.5	0.0	3	23	257	278	255	278	0.93
6	17	0.17	12	6.3	0.2	1	23	605	627	605	627	0.95
7	17	1.3	93	3.6	0.1	1	23	666	688	666	688	0.90
8	17	0.00027	0.019	15.2	0.2	1	23	733	756	733	756	0.93
9	17	0.038	2.7	8.4	2.1	1	23	763	786	763	786	0.97
10	17	0.0037	0.26	11.6	0.5	1	23	818	841	818	841	0.98
11	17	0.12	8.7	6.8	0.2	1	23	1169	1193	1169	1193	0.94
12	17	0.00053	0.038	14.3	0.2	2	23	1202	1224	1201	1224	0.96
13	17	0.0083	0.59	10.5	0.1	1	23	1231	1253	1231	1253	0.97
14	17	9.6	6.8e+02	0.9	1.2	2	20	1261	1279	1261	1282	0.93
15	17	0.024	1.7	9.0	0.4	2	23	1505	1526	1504	1526	0.95
16	17	0.0077	0.54	10.6	0.0	1	20	1536	1555	1536	1559	0.95
17	17	0.031	2.2	8.7	0.3	1	23	1567	1589	1567	1589	0.95

Sequence Information

Coding Sequence: ATGCCGTTCAAGTGTGAATACTGCGCCCGACTGTTCAAGCACAAGCGATCCCGCGATCGCCACACGAAGCTCCATACGGGCGATCGACGCTATCGGTGTCTGCATTGCGAGGCTGCCTTTTCGCGAAGCGATCACCTGAAGATCCACATGAAGACGCACGACAACCAGAAACCGTTCCAGTGTACGATCTGCAACCGGGGCTACAACACGGCCGCCGCCCTGACGAGCCACATGCAGAACCACAAGAAGCAGCTGGCGCTAACGGGAAGTCCGAACCTGACCTACAGTCCGCGTTCGACCACCAGCTCACTCTCCAGCGGTGGGGGAAGCGGTGGTGGTGGTGGCAAGCGGGCTGGAAAGTTCTCCCCCTACGGCACCGACTCACTGTTGCTGATGGGACGCACCTCCAAGCAGTTGGCATCGTTGGCGAAGTCGGGTGGCTCCTCAGGTGCAACCTCGAACAACAATCGAACACCAACTCCTGGAGGAGGGGGAGCTACGGCGGGTTCCCAGCAGCAAGATCCACTGCTCTCCTGTCCGTACTGCACGCGTACCGATTTCCCCTCGCTCGAGCAGCTCGGCCTGCACGTACAATCGATGCACGGACACCCGGGAGCGCTCGGAATGCTCGATGCAACGACGCCCTTGCCATACTTCGCCCCTCACCTGCGCGGCGGTGGTGGTGGTGGGGGACCCGGGCTAGGTCGACGAGCGGTCACTCCCGATGCGAACACACTCTCCCTCGGCTCGTCCTATCCGCCGATTGCGTGCGAGTTCTGCACGATGAAGTTCCCAACCGTTCCGCTCATGATTGCCCACCTGAAGGCGTCCCATCTGGACCGGTGGGTTGGCACGGGTCGGGGGGCACCGAGTGAAGGTGGTGGAAGTCCTTCGGGAAGTATGGGACCATCCAGGCCCCCCTCCGGGTATCACCCGTTGGATCAGCTGCAGTTTAACAAGAGTCTTCTGAGTGGTCCGTTCTCTTCGTTCTACGGTGGAGCGTTTGGTGGCGCGACGAGTTCGGCCAGCGTGAAGGTAGAGCGCCGTTCCGCAGGACCGATGGGAAGAGATGAGAATGGGAACGAGGCAGATGAACCCACCGTTAAGCGGCGTCGGCGAGAGGACGATAGTGTCGAAGAGGAGAACCGTGAAGATGAACCAAAGGAAGTCGCAAACCAACCGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNACCCGCAAGAGGACGAAAGTCGACGATTAAACCGATCAACGGAAGGCTCTGAAGCTGGTGGAAAAGTGAAGCAGGAACAGAACGACGCCACATCTCACTCGTCCTCGGCTCGCTCGTCACCTTGCGAGTCGGTCGCATCGTCCACGCACAACCCCGGCCACACTTCCGGTGGAGAAAGTCCAGCCGAGCAGCTAACCCCAACCGATCTCAGTCAACCGAAAATGAAGCGTCTCAAACTGGAAGCCCCGGACGATGAGAGGGATGGTGATGAGGGAAGGAGAACCCAACAGCGTCGTGGATCACGAGGAGCACACATCCGGCGGGAGAGTGAATCGAAGGAGTTCGCTGCATCGCTGCAAGGTCCTTCGCTTTTTGCGTCACTTCAACAACAACATCACCAAGCTCAACATCACACGTCCGTGGGGACAACTGCGTCCACCAGTATGGCACATGTTTCGCAAGCTCCCTCGATGCCATCAGCACCACCACCTGCACCCCCACCACCCGGTGCCTACCTCTGCAATCAGTGTAATGCCGCCCTACCCGACTTCGAGTCGTTCCGTACGCACCTGAAAGCTCACCTCGAACAGAGTGCCGCCAGCGCCGCGGCAGCGATGCGACTCTCGGGTGATCCTTCCTCCACCGTCGGCAACACCGGAAACGGTGCACCAACCGGTGCCCTCTCCCTGTCCGCCTTTCTCTGCCAACAGTGCGGTGCAACGATGAACAGCCAGGCGGAGTACGAACAGCACACGGTCGGACACTACCTGGTGACGGCGGTGGAGTACCGTTGCCAGGCGGCTGGCACGTCCTCTTGTGCCTCCACCGGGAAGGCGTCGTTCGGCAAAATGGAGGACCTACACAAGCACCTCTACGAGGGACACATGCAGCTGCTGTACAAGTGTACCGTTTGTGGGGAAACGTTCGAGTCGAAGGTGCAGGTGCAGGTGCACTTTGCCGTTAACCATTCCGTGGAGGTGAAGCTGTACCGGTGTTCGGCTTGTGCGGAAGTCTGTCGCACCGAGCGTGAATTTCGACAACATATTCGCAACCGCCACTTGGCTGCCGGAGCCGTACAATGCATGTTCTGTCGAATGGTTTGTTCCTCCGAGCTCGAGATGCACTTCCATCTGGCTTCTCATGCGCGAAAGTTTAAATGCCCAGCCTGTCCGGAATCATTTCATGTGGAGTTCCTGCTCGATCGGCACATCCAGACGCAGCACAGTCAGAAGGAAACGGTGTCGGACACGAACAGACGGGAGTGTAACTCGAGCAACAACCAACAACCAATGTTGGGAGCTCCATCCTCCACCGGGAACAACAGCTCAAACGGACAACCTTCGTCATCGGCGGCAAACGTCATCTCTTCGTCTGCGAGCGTCACCGTTACTTCGACGGGCTCCACCGCTCCATCAGTTTCCGGTGCGTCCTCGAGCCTCGAATACCTTCAGCTGCAAGGGCAGATGGCGGCGATGGCAGCGGCAGCGGCGGCTGCCTCGACCGGTTGGCCCAGTCTCTACCAGACGGCGAACAAATTCTACACCAATCCCCTCCAAGTGGATACCTTGAGCCAGCTCAAACATCCACAGCATCTGCTTCACGGATTCTATGATTCGATGCTGGGCAAAACCCAACAGCAACAACAGCAGCATCGTACGAATTTTATTCCCGAACCGAGCACAACCGGATCGGGCGTTGGAAGCAACAAGAAGAACCCTTTCCTAGGCCTCTCGCCAAACTCTGGTTCCGCGAAGGTTGCCAACACGCTGCTCGGTCTCGGATACGGTGCCACACCCGGGGTAGGACATTCGCAGCGTTCTTCAACCGGAACTGGTCCCGTCAACGGTTCGGGTGTGTACTCGCCCGAGTCTGGAGCCCAATCCAATCCAACCAACAACCACCAAAACGTTCCGGCCAATCCCAAACTCTACTCACCGATCTCGATGATTCAACGTTACGGCGAAAATGGACCTCTGTCGGGTGGCATTGCCAGTGGAGAGCGAGTTATTTCACCTACCAACGCCACCGGGTCGTTACATCATGGTCCCCTGTCGGATCAACAACCGGAGCAAGTGGGAAGAAAGGCCACGAATGTAGCTTCCACCGGTGGAAAAGGTTCCGAACGTTCATCCACCATTCCGGGAAGTGGCGCTTCAAGCTCAACTTCGGGTCCTTCCGCTGCAACGGTAGCGAGTAACTGCTGCTACAGTTGTGGGATTTGCGAACGGACCGACTTTAGCACGGAAAGTGAAGTGCAAACGCATCGCAAGATCGTGCACAACTTGAAGACGGGTGTTAGCTTGCGGTGTGCGTACTGTAATGGAGATTTCCGATCAAGAAACGAACTGGAAAACCACATGAAGATCGCACACAACACCGGAGGTGGCAAGCACAAGTGTCTGATCTGTGACGAGATCTTCCCTTCACCGGCCGTCCTTGCCGAGCACAAGCTGTCCCACTGCAAGGTCGGTGCGTCGGGCCGCTGTTCCCATTGCAGTTTGCCCCTTCCGGACGTGCACACCTTCAAGCAGCATCTTCCGGCCCATCAGGCGCCTCCATCGTCCGCCAGTGCGACGGCTTCAGCTGGATCGAATGCAGTTGCTTCGGCCCCGGGAGGAAATTCCACTTCAACCGGGGCTACAACAGCGACCGTCGTTGGAAGTTCCGGTGGTTCGTCTTCCAACACGACGAATTCGACAAACGGTTCCAGTAGTTCCGGTGCTGGTGGTGGCCAATCGGAACAGGATCGTTTCCCGCAGCAGTGTATTTGCTGCCGGCAGACGCTGAACTCGGAGTTTGAGATCAGTCTTCATGCTAAATTCCACACAAAATCGCCCGACACCAATGAACGCACGTGTGCCCTCTGTCTCGAACCGCTACCATCCCAACCAGAGTCGTCCACTAAGATTTGCGATCCGTGTCTGAAACGGCACAATTTCCCCTCGAAGCTACTGTCGATGAACTTCCTAAAACCTCCACATCAAACGGGAAATACTTCCCTCGTGGGTGTGTCAACACCGGCGCCATCCTCCACAGCTGGCCATTCCGTCCAACTCCAAGGTCCGGTTCCATCCTCCACCGTCCATTCGTTCGGTAGCAATGGACAGACAACGGCAAACGGTGGTGAAACGCGACCAAAACACCACCACCACCTTGCGTACGAACAACCCGTCCCGACCGATGGCAACAACCCGGGCACCCCAAACATCGTCCAGTGTAACCTCTGCAAGAAGGGTCTCCCATCGGCGCACAAACTCCAGGAGCATCTGATCGACCACACGTTCGCCGGATGCGAGGAACGCGGCTACGTGTGTTACCTCTGCTCGGCCGTGTTCACGTCATCCGGTGGCCTCCAAGCGCACCTTCCGCTGGCACACTCGAACACCAACGCCAAACCGTACGACTGCGAGCGGTGTGGCGTGGCGTACTTTTTCCGCGCCGAGCTGGAGCATCATCTGATCGATCACGAGTTGGGCCACGCTTCCGAGGACCGATGGGTGCGACCGGTGTCATCCCCTTTGCACACTCAACGGGGACACATCAAGCAGGAGCAAGGGGAAGGAGATGACCACGAGCGAAGCCTACCCTCCGGGACGCCACCAGCGTTTGCGAAGGAAGAGGAGGAGGACCATTCGGAAAGGGGAGATTCCCCGCAGGAACTCGAGGAAAACACGACGTCCAGGAGGACGAGCAAACGAATAAATCCGACACGGAAACGGTACAAGAAAGGACCGGTGGAGACGACGTAG
Protein Sequence: MPFKCEYCARLFKHKRSRDRHTKLHTGDRRYRCLHCEAAFSRSDHLKIHMKTHDNQKPFQCTICNRGYNTAAALTSHMQNHKKQLALTGSPNLTYSPRSTTSSLSSGGGSGGGGGKRAGKFSPYGTDSLLLMGRTSKQLASLAKSGGSSGATSNNNRTPTPGGGGATAGSQQQDPLLSCPYCTRTDFPSLEQLGLHVQSMHGHPGALGMLDATTPLPYFAPHLRGGGGGGGPGLGRRAVTPDANTLSLGSSYPPIACEFCTMKFPTVPLMIAHLKASHLDRWVGTGRGAPSEGGGSPSGSMGPSRPPSGYHPLDQLQFNKSLLSGPFSSFYGGAFGGATSSASVKVERRSAGPMGRDENGNEADEPTVKRRRREDDSVEEENREDEPKEVANQPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPQEDESRRLNRSTEGSEAGGKVKQEQNDATSHSSSARSSPCESVASSTHNPGHTSGGESPAEQLTPTDLSQPKMKRLKLEAPDDERDGDEGRRTQQRRGSRGAHIRRESESKEFAASLQGPSLFASLQQQHHQAQHHTSVGTTASTSMAHVSQAPSMPSAPPPAPPPPGAYLCNQCNAALPDFESFRTHLKAHLEQSAASAAAAMRLSGDPSSTVGNTGNGAPTGALSLSAFLCQQCGATMNSQAEYEQHTVGHYLVTAVEYRCQAAGTSSCASTGKASFGKMEDLHKHLYEGHMQLLYKCTVCGETFESKVQVQVHFAVNHSVEVKLYRCSACAEVCRTEREFRQHIRNRHLAAGAVQCMFCRMVCSSELEMHFHLASHARKFKCPACPESFHVEFLLDRHIQTQHSQKETVSDTNRRECNSSNNQQPMLGAPSSTGNNSSNGQPSSSAANVISSSASVTVTSTGSTAPSVSGASSSLEYLQLQGQMAAMAAAAAAASTGWPSLYQTANKFYTNPLQVDTLSQLKHPQHLLHGFYDSMLGKTQQQQQQHRTNFIPEPSTTGSGVGSNKKNPFLGLSPNSGSAKVANTLLGLGYGATPGVGHSQRSSTGTGPVNGSGVYSPESGAQSNPTNNHQNVPANPKLYSPISMIQRYGENGPLSGGIASGERVISPTNATGSLHHGPLSDQQPEQVGRKATNVASTGGKGSERSSTIPGSGASSSTSGPSAATVASNCCYSCGICERTDFSTESEVQTHRKIVHNLKTGVSLRCAYCNGDFRSRNELENHMKIAHNTGGGKHKCLICDEIFPSPAVLAEHKLSHCKVGASGRCSHCSLPLPDVHTFKQHLPAHQAPPSSASATASAGSNAVASAPGGNSTSTGATTATVVGSSGGSSSNTTNSTNGSSSSGAGGGQSEQDRFPQQCICCRQTLNSEFEISLHAKFHTKSPDTNERTCALCLEPLPSQPESSTKICDPCLKRHNFPSKLLSMNFLKPPHQTGNTSLVGVSTPAPSSTAGHSVQLQGPVPSSTVHSFGSNGQTTANGGETRPKHHHHLAYEQPVPTDGNNPGTPNIVQCNLCKKGLPSAHKLQEHLIDHTFAGCEERGYVCYLCSAVFTSSGGLQAHLPLAHSNTNAKPYDCERCGVAYFFRAELEHHLIDHELGHASEDRWVRPVSSPLHTQRGHIKQEQGEGDDHERSLPSGTPPAFAKEEEEDHSERGDSPQELEENTTSRRTSKRINPTRKRYKKGPVETT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00109344; iTF_00096578;
90% Identity: -
80% Identity: -