Basic Information

Insect: Anopheles sinensis
Gene Symbol: salm
Assembly: GCA_000441895.2
Location: KE524999.1:867596-876968[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 9.7e-06 0.00069 19.7 1.5 1 23 503 525 503 525 0.98

2 7 5.1e-06 0.00036 20.6 1.9 1 23 531 553 531 553 0.98

3 7 0.062 4.4 7.8 1.9 2 23 875 896 874 896 0.97

4 7 1.2e-08 8.7e-07 28.9 1.5 1 23 902 924 902 924 0.98

5 7 0.00047 0.033 14.4 3.1 1 23 934 956 934 956 0.98

6 7 0.0019 0.14 12.5 2.1 2 23 1165 1186 1164 1186 0.97

7 7 2e-07 1.4e-05 25.0 1.3 1 23 1192 1214 1192 1214 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	9.7e-06	0.00069	19.7	1.5	1	23	503	525	503	525	0.98
2	7	5.1e-06	0.00036	20.6	1.9	1	23	531	553	531	553	0.98
3	7	0.062	4.4	7.8	1.9	2	23	875	896	874	896	0.97
4	7	1.2e-08	8.7e-07	28.9	1.5	1	23	902	924	902	924	0.98
5	7	0.00047	0.033	14.4	3.1	1	23	934	956	934	956	0.98
6	7	0.0019	0.14	12.5	2.1	2	23	1165	1186	1164	1186	0.97
7	7	2e-07	1.4e-05	25.0	1.3	1	23	1192	1214	1192	1214	0.99

Sequence Information

Coding Sequence: ATGAAGGAGAATGGTTGCATCGATAACGAGGGCACAATCGCGAAACCGTCGGCGCAATTGTTAGCGAAGATGTCGGAGGAATATGCCGAAAAGGCGGCGGCGGCAACGCGACTGAACGACCATCATCTTCATCATGCGCATTATCAGTCGGCGGCCACGACAGGTCGCCATCAGGAGCAGGCCTCAGATCGGGCGGACGAGATCGCGCATAACGAGGATAATTTAAGTGACGATGAAAACAATGACGACGAGGAGATGGCCGACGGGACGGCGGTGACGGCGGCGGCGGGGTCGGGGGCGACTGCAAACGATCGGGAAAGTGGCCACGAGAGCGGTGGCGAAAGCCGAGACGACCGAAAGGGGCCGGGAAGTGAGTGCGCCACGGGTCGAAGCAGTCCACGATCTCCAGTCTCGCTCGTGGGGCGAGGTGCGGAAGGGCTGGGCGCGATGCTATGTGGAGCCGGTTCGGGAGATGATCCTTCCGCGACGGCAGCAGCCGCCGCCGCAGCAGCCGCCCTCGGAGGTCCCGCAGCAGCCGCCATTGCAGCGGCAGCAGCCGCCGCGGCCGCAGCGAAGGGCTCGATACCGGGGGCGGTAGGAGGTGGAGTGGGGCTACCGGGGGCCGACTTCAACCCGGCGGCAGCGTTCGGTTTCCCGGCAGCACCCGCGCCCGCCCCTGGCATGTCCATTCAGGCCTTCCAGAACGCCATCGCTCAGTTCACGGCGAACGCGCTGGCCAACAACATGGACAACGACACGGTGGTGAAGAACCTGGCCATCCTCCAGTCGGCCCTGTTCACGCTGCAGCAGCAGCAGTTCCTTCAGTTCCAGCTCATCCAGCACCTGCAGTCGCAGTTGGTCAAGAAGCACACGGAAAAGGAGGACGACGAGGAGGAAGTGGAGGAGGAAGGCATCGAGGATGCGTTCAGCAAGAGCTATCAGATGGCGAACATGATGGCGGCGGCCGCCGCAGCCGCTAAAACACACGTCCCGAACCACGTCAACGAGCTGTTGTTGCGGCCTTCGATTCATCCCGTTCCGGAAGAGGAGCTAAGGAAACCAAAATCATCGGAGGCGAACAGCATCTTCGGAAGTAGTTCACTGTCCTCTTCATCATCTGCGGGAGAGAAGCGGACCGCGAGTGAATCGGCGTCACAGTCCAACGCAGTGTCCGTTTCGTTACCATCCTCCACGGCTCAAACCACCACCTCCAGCACGAACAGCGCAAATGCCAGTGGACGATCGGAAAAGGACGAAATCTTGACCTACCACCAGGAGCACGGCGGTTCCATGGGCAGCTTCTCTTCGTTGGCGGCCAACATCATAACCGATCACGCCCCGTCAATGCTGGGCGAGCCGAACTCGCTGGCCATGTTGGAGAAGAAGGCACAGGAAGTGTTGAACTCCGCGTCGCAGGGAATCCTCTCCAATAACTTGCTGGATGAGTTGGCCTTCGCTAACGATAAGTCGTCTCCAAATGGGCGTAACGACGCGGCACTATTTAAACACCGGTGTCGGTACTGTGGCAAGATCTTTGGCTCCGATTCCTCGCTGCAGATCCACATCCGGTCGCACACGGGCGAAAGGCCATACAAGTGTAACGTGTGCGGGAGTCGGTTCACGACTAAGGGCAACCTGAAGGTTCATTTCCAGCGGCACTCGGACAAGTACCCGCACATCCCGATGAACCCGAACCCGGTTCCGGAGCATCTGGACAAGTACTTCCCACCCCTGATCCCTCAGGAGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGTCTGGCCAACCACCCTCGCAATCGTCCCCCATGCCGACGGGAGGTTCGGCAGGTCCAGGTGCTGGCGGTCCGGGCACATTCCCCGGAGCGTTGGATGGACGCGCTCCGGCTGGTTTCCCTCCGCGAGGTTTCTTCCCGGACTTTTACATCCCACGACCACCACATGCCCAACTTCAGGAACTGTTCGGTGCTTCGGCAAACGACGCTGTGGCACGCAATCCGGTCGATCTGTCGCAGATGAAGAAACCGGAACCGGTGCCACCAACGCGCGATCCTACCCCCGAGATGCGCCATTCGCCCGAACTCTCGAACGATGCGATCTCGTCCGCGAAGATCAAGCAGGAACCGATGGAAGAATCGCTCGATCTGTCAGACAAGTCCTCGAAGGTGGCATCCGCAGTCCCAACGCGATCAACCAGTACGCCTATCCAGCATCACCATCACCCTCACCGAGATCACGAGGAGTCGAAGGATTCGTCCAAGGATGAACCACACCTGTTGGATCAGTCGGATCAGCTGAAGGAGGACAGTGGGACCGTCGGCGGGGGCGGTTTAAACAACTCGACCAGTGAGAAAGAGTTCCCATTGAAGCTGAAGAACAACTCGATCGAGAACTTGGCAACGGTACCGTCGGTGTCACCTCCTTCCAGCTCATCCTCGGGCTCGCTCTACCAGGACACGGTGCTGGACCCTTCGTTCTACGCCGCGCATCTCCCGCGTCCCGATAGCAACGACAGTTCGTGGGAGAACTTCATCGAGATCTCGTCGGAAACGTCGAAGCTGCAGGAGCTGGTGGACAACATCGAGAACAAGACGTCCGAGCCGAACCAGTGCCTGGTGTGCAAGAAGGTCCTCTCGTGTCGAAGCGCCCTCCAGATGCACTACCGTGTACACACGGGTGAGCGTCCATTCCGGTGCAAAATCTGTGGCCGCTCGTTCACTACCAAGGGGAACCTGAAGACGCACATGAGCGTACACCGGATCAAGCCACCGATGCGTACCCTGCACCAGTGTCCCGTCTGCCACCAGAAGTTCTCCAACATCTTCGTCCTGCAGCAGCACATACGGTTGCACACGGGAGAGATGACGGACCTGACGCCGGACCAAATAAAGGCCGCCGAGATCAAAGACTACGATGAGAATGATCACGAGAATGGCGGAGGTCAGCAACATCAGGCGTCGATGGATCGTGGTACGACCCCCATCGGCAAGATGCCCAAGGTCCCGATTCACGAGAAGCTGAAGGTCAAGACGGGCCTTACATCGCCCGCCATCGACTCTCAGGTGGAGGATCTGCGCACGATGAACCTCCAGCGGCTGTCGATGCGGTCGCTTCCGCCGGCCGAGGACGGGTTCTCCCGTGACTCCTCCTCGGCAAGTCCCACAACCGCCACCTCCGACGCCAAGCGACTCCGCTCGTCCAGCCCCTCGAACGCGTCCTCCTCGACGATCCACTCGCGTCGCTCGCCCATCTCAACTCCACCGACCGTCGGAGGCGCCGAGCAGGCCAGTGCCGCCGGACGAGCCGCTGCGGCCGCCGCAGCCGCCGTTGCCTTCCCGTACGGACCACCCTTCCTCGGCATGCCCCAGTTCCCGCCCTTCATCAACCGGCCGCCCTTCCTCGGCAACGTTCCGATCGTGCCACCCGGTTCCAGCATGCCACCGTTCGGACTTTTCGGCGTTCGTGGAAACACAACAACTTGTAATATTTGCTTTAAAACTTTCGCCTGTAATTCCGCACTCGAAATTCATTACCGAAGCCATACGAAGGAGCGCCCATTCAAATGTTCAATCTGCGATCGAGGATTCTCTACAAAGGGAAATATGAAGCAGCACATGCTCACTCACAAAATCCGTGATATGTTCGGCAGCTCGGGTGGCAATTCCGGTGATGAGTCACGAACTCAGACACCGCCGCAGGACAGCCATTCGCAGTCGTCCAACGGCTCGGAATCCCACCAGCAGCAGCAAAACCATCACCAGCAGCAGGATGGAGCCGCCCAGGACTTCACTCCTTCCGGCGGTGGCCACCGGTATGGCGGCGGAAGTCGCGAACGCTCCCGTTCGGCAGGAAGCTACGACGGAGCGCCCTCGGGTGGCAAGCAGTCGGAAGCAAACGAAGCCGGTCTTGCGGCGTCCATGCCGGACGAAAACGGTTCCAGCAGCCTGCAGTCGAGTGCGTCGGACCGGGGTAGCTCACCGACGCCGCTAATGGCCGGAAGTGCAGCCGCAGTGGCCGCTGCTGCCGCGGCCGCCGCCGCCTCGAACAACAACTACAACGAGTACATGGGCAAAGAGGTGGTCGATCTGAAGAATTGGTGCCAGAAGCTGAAGGAAATGCCGGAGAACATTGCCGCAAGTTGA
Protein Sequence: MKENGCIDNEGTIAKPSAQLLAKMSEEYAEKAAAATRLNDHHLHHAHYQSAATTGRHQEQASDRADEIAHNEDNLSDDENNDDEEMADGTAVTAAAGSGATANDRESGHESGGESRDDRKGPGSECATGRSSPRSPVSLVGRGAEGLGAMLCGAGSGDDPSATAAAAAAAAALGGPAAAAIAAAAAAAAAAKGSIPGAVGGGVGLPGADFNPAAAFGFPAAPAPAPGMSIQAFQNAIAQFTANALANNMDNDTVVKNLAILQSALFTLQQQQFLQFQLIQHLQSQLVKKHTEKEDDEEEVEEEGIEDAFSKSYQMANMMAAAAAAAKTHVPNHVNELLLRPSIHPVPEEELRKPKSSEANSIFGSSSLSSSSSAGEKRTASESASQSNAVSVSLPSSTAQTTTSSTNSANASGRSEKDEILTYHQEHGGSMGSFSSLAANIITDHAPSMLGEPNSLAMLEKKAQEVLNSASQGILSNNLLDELAFANDKSSPNGRNDAALFKHRCRYCGKIFGSDSSLQIHIRSHTGERPYKCNVCGSRFTTKGNLKVHFQRHSDKYPHIPMNPNPVPEHLDKYFPPLIPQEXXXXXXXXXXXXXXXXSGQPPSQSSPMPTGGSAGPGAGGPGTFPGALDGRAPAGFPPRGFFPDFYIPRPPHAQLQELFGASANDAVARNPVDLSQMKKPEPVPPTRDPTPEMRHSPELSNDAISSAKIKQEPMEESLDLSDKSSKVASAVPTRSTSTPIQHHHHPHRDHEESKDSSKDEPHLLDQSDQLKEDSGTVGGGGLNNSTSEKEFPLKLKNNSIENLATVPSVSPPSSSSSGSLYQDTVLDPSFYAAHLPRPDSNDSSWENFIEISSETSKLQELVDNIENKTSEPNQCLVCKKVLSCRSALQMHYRVHTGERPFRCKICGRSFTTKGNLKTHMSVHRIKPPMRTLHQCPVCHQKFSNIFVLQQHIRLHTGEMTDLTPDQIKAAEIKDYDENDHENGGGQQHQASMDRGTTPIGKMPKVPIHEKLKVKTGLTSPAIDSQVEDLRTMNLQRLSMRSLPPAEDGFSRDSSSASPTTATSDAKRLRSSSPSNASSSTIHSRRSPISTPPTVGGAEQASAAGRAAAAAAAAVAFPYGPPFLGMPQFPPFINRPPFLGNVPIVPPGSSMPPFGLFGVRGNTTTCNICFKTFACNSALEIHYRSHTKERPFKCSICDRGFSTKGNMKQHMLTHKIRDMFGSSGGNSGDESRTQTPPQDSHSQSSNGSESHQQQQNHHQQQDGAAQDFTPSGGGHRYGGGSRERSRSAGSYDGAPSGGKQSEANEAGLAASMPDENGSSSLQSSASDRGSSPTPLMAGSAAAVAAAAAAAAASNNNYNEYMGKEVVDLKNWCQKLKEMPENIAAS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -