Basic Information

Insect: Anopheles sinensis
Gene Symbol: ZFY
Assembly: GCA_000441895.2
Location: KE524591.1:41174-50970[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.00066 0.046 14.0 1.7 2 23 764 786 763 786 0.95

2 8 0.026 1.8 9.0 0.1 1 23 1003 1026 1003 1026 0.97

3 8 2.7e-06 0.00019 21.5 1.1 2 23 1033 1054 1033 1054 0.97

4 8 0.00011 0.0079 16.4 0.5 1 23 1060 1084 1060 1084 0.98

5 8 2.5e-05 0.0018 18.4 2.4 1 23 1094 1116 1094 1116 0.95

6 8 4.5e-06 0.00032 20.8 0.4 2 23 1127 1148 1126 1148 0.96

7 8 1.4e-07 9.7e-06 25.6 0.2 1 23 1154 1176 1154 1176 0.98

8 8 0.0013 0.094 13.0 0.4 2 20 1184 1202 1183 1204 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.00066	0.046	14.0	1.7	2	23	764	786	763	786	0.95
2	8	0.026	1.8	9.0	0.1	1	23	1003	1026	1003	1026	0.97
3	8	2.7e-06	0.00019	21.5	1.1	2	23	1033	1054	1033	1054	0.97
4	8	0.00011	0.0079	16.4	0.5	1	23	1060	1084	1060	1084	0.98
5	8	2.5e-05	0.0018	18.4	2.4	1	23	1094	1116	1094	1116	0.95
6	8	4.5e-06	0.00032	20.8	0.4	2	23	1127	1148	1126	1148	0.96
7	8	1.4e-07	9.7e-06	25.6	0.2	1	23	1154	1176	1154	1176	0.98
8	8	0.0013	0.094	13.0	0.4	2	20	1184	1202	1183	1204	0.94

Sequence Information

Coding Sequence: ATGGCCACCCTAAACTGGAGAACGCCCGCGGCACCTAAAAATGCGGCCCCACAAACTCATCATCATCATACGCACCACCCACATCAAAGACTTTCGGCTGGCGTTCCAACCGGTGGTGGATATGGTTATTATGATAAACCATCGACAAACAACGTGGTACGTCACCCGGCCGCCAATAGAAATGCACCGCAACCGGTCACTGTACACAAGTCCCCGATCCTGCCGCCGGTCCCACCAGCTTCCAGCTGCCTTCCGGACGAGGTGGAGGACGATTTAAGCGAAATCACGATTCAGTTCGACGATGGGGTGCAAACGTTGTACGTTGGTCCGGTTGAAATAGTCGACAAGGGGGATGGTGGTGGTGGTGGTAATGCATCCCCACAAGCAGCTGCCAGCAACCCGCCGAGCCTAGGAAAGGATGGTGGCAGAAACGGAGCGAAGGAAGAGAATGTGACCATCCGAGGCAGTGGTGAGGGTGTACGGGCGCGCGAACGGTTCCAGGAGGAACGGGCGATCGTCACGCTCGAGCCACAATCGCTGTGCATCAAGCAGGCACCGATGTTAAATTTCGCCCGTGCAGCCACATCCACCATCGCTCCCACGAACAACGCCAACGTAGTAGGCTCGAACCGGGCAGTTCCTCCTACCGCCCATCTTACCGTTGTACCGGTTGCCTCGCTTAGGGACGACAATCACAGATCGGGCAACGCAATTAATCGCGTTTCGGTACTCCGTTCACCACCGCAACCGATAGCGGTAGCGGCAGCACCGGCTTCCAAGCATCAACCGCCGGCGGCGACCGCCGCAACCGCGACCGCAACAGCAGCGGTTCCGGTTCCGGTATCAGCACCACCGCCACTGCATATCCTCACGACAATCAAGCAAGAACCGGACGTGGCACCCGAACTCGTCGACGATGGGAACCACACGCTCCCGAACGAGGGCAACAGTGGCGAGCTGCTGCAGGAGACGACGACGCTGGTAGAAGAGAAACCATTGCTGGCTAACGTGGTATCCGTTGCGGAAGATTCGACGGTCGGTTCGGTTCCGACGAGTAATGGCGGTGCCGCATCGTGCGACGCTGCTGTTATGACAGCCGCCTCCGTTATAACCAATACCAGCGCAACCCAAACGCTGCTGGAGGAGGATATCAGCGGTGGTACGACAGCGGCGGTAGTAATATCCGCTGAGCTGGCGAAATCGGCAAAGGATCAAGCAAGTTCCACTAATGTCGTACAGCAAGAAGTATTCGAACAGCAGGTCGTACCGGAGGCGAACCTAAACGCAGCAGTCCATGATCCTGCCGATGATGTCCAGCCTGTTGTTGGAACGGAACCGGCAGCCATTGTTGAACACAAAGCGCATCAGCAGGTCGTCGCGGCGGAAGTATTGCCCGATGCGTCACCGTCATCGGATGTTACAGCTACACAACTGCAAATACCACCTCCACCCCCGAAAAGAGGTCGTGGACGTCCGCCGAAGGTGCCGAAAATACCTCCCTCTCCGGAAGTAGCATCCGTGAACGCTGCGGCATCGAATGGCTCACCGTCGCCGGTAAAGTCCTACATATCCGTGTCGGCACTGTTCAAGCCGAAGAGCAAACGGTCCCGTAACGTAGAGGAAGCATCTGCAGCTACCATCGTGAGCGAAGAGGAGATTCAAAAGAAGACTGAAGGGAACGAAGTAACCACCATCGGTTGTGATGTTGAGGGTAAAAGTCTTTCAAATGGCGAAGGCGAAGGTAAAGCGACGAACGTACCGAAGGAGGTTAAAGTGCGATCGCCGGCATCGCTGAAGGCGAAGGAAATCGAATCCGTCCTGGAAGAGCCCACCGCGTCGGTTGGAAAGCAGCTCGAAAGCAGCTCCGCCGTTGTGAAAGAGGCGGAGAAAGAATCATCCCCCGGTTGTGACAGCGGTATCGAGTCGGTAAGCGATTCGACGACGACGGTAAAGAAGCACCCAACCCGTGGCCGTCCAAAGTCCAGCTTGAGCGCGGCCAGTGAGGAAGATCGTGATCGGATCCCATCCGTCGCCAGTAAGGAGAAGGAAAACGGTGACGGAAAAAAGCGTCGTTCGGGTTCGTCCGTTCCAAAACCAACGGTCCAACACTCGGGGACTCGGGATGAGGAAGAGGAGGATGACGACGACGACGAGGACGAGCAACAGCCGCTCAAAGGGTTGAAAAAGCGCACGGTCCGGACGTCCCGGAAGCCATCGGCCAAAGCGAAGGAAGCGGCCGAAGCTGCCGAAGTCGCCCAATCGGTTGCACTTTCCTTCGGGGACGAGATTCAGTGCTGCAAGTGTGACATGTCGTTCAAAACGGAGGCCTGGTACCGGAAGCATCTGATGAACGCACACGAGCTCGATCTAAGCCAAGCGGTTCAGCTCTTATCGTCGTTGGTGGCTGAGAGAGGAACCGATGAAGAGGTTCCAACGTTGGAACCAACACCACCAAGTGGTGACGGTGAGATAAATGGCGCAATAGAAACAGAACCCGTAAAGGCAGACGACGGTGGCTCACCGAAGGATAAAACGTCCGAGCACAACCGGGGAACAAAGGTGTCGAAAAAGGAATCACTCTCTCCCTTGGCATCTTCTTCAGCGTCGTCCCGTAAGCGAAGTAAATCGACGATCTCGAGTGAAGACGGAGGAAGTGCAAAGCGAGTAGCAGTGGAGACGGGTTCGAATAGAAAGCAACCGGCCACGGTTCAACAGAATGGTGTCTGTAAAAAGGAGATCAAAGTAGAACAGCCGCCGCAGAGAACTCCTTTCCAGCGGAATGACGACGACGCTTCTATGGAAGAGCAGAACGGAGAGGTGGAAGGTTCCCAGCAGACACCATTAATGGACGATTCGGCCACGCCGCTGGAAACGAAACCGCAAACGAAACAGGAACGCTACGAACCGTACGATCCTTATGAAGGAGATCCGGAAAAGCTGTCTCCTTTCGAGGAGGCGAAAGTGATCGTCCTGGAATCGGACACCGATGGTGGTGGTTCGATGCTGTTCAAGTGTACCATCTGCGACGGTCAGTTTACGGACATTCCCGCCATCAAGGAGCACCTGTCGACGGTGCATGCCGCGATCAAGCGACGCTCCTGCGAACACTGTGGCCGTACGTTCGTGCAGACCGGCGACCTGACGCGTCACGTACGCATCCACACCGGACACCGGCCTTTTAAGTGCCCATTCCCCAACTGCACGTACGCGTTCATCTCGTCCGGCGACCTGTACAAGCACGTGCGGCGCCACAATGCGGACGTGGCGCTGCCGAAGCCGCACGCCTGCGACCAGTGCGGCAAGGACTTCGAGCGCTCGTACGATCTGAAGCGCCACAAGACGATGCACCTGAAGCAGCAGCCCGGTTTCACCGGGATTACGTGCGAAGTGTGCGGGAAGGTGTTCGCCCGGAAGGACCAGTACCGGGCGCACACGTACCGCCACATGGGCGTCCGGCCGTACCAGTGCGAGGTGTGCGGGAAGGCGTTCACCGATCCGAGCAACTACTCCAAGCACGCCCGGTTGCACGAGCTGGACGGCATCGAGGTGGTGTGCGACTTTTGTGGGCGTCCGTTTAAGAACAAGAGCGCCATCTCGAAGCACATCTTTCACTGCCAGCAGAAAAAGATGCGACGGATGGCGGCCAAGGTGGAGAAGGGTGGCGAAGGCGATGATGGTGGCAGCAGCAAAACAAGGCGCGTTGGAGTTGCGGCCGGCGGCGGGTTCGGTAAGTCGGAAGACACTGGCGCGCTGGTGGAGGCTCCGTTGAAGCTTAAGCAGGAACCGCAGGCTCGAAAGCAGCGGAACGGTGGGAAGAACGGTTCGAAGCGAAAGCGACGACGACGAGCCCGCTCCGAGACACCTCAGTCATCTTCCGCCTCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNACGTTCCGTAAAGCAACGGAATCGACGCAGTAACTACAAGAATGGGGTTACCTTCGAGGCGACGACGCCTTCGTAA
Protein Sequence: MATLNWRTPAAPKNAAPQTHHHHTHHPHQRLSAGVPTGGGYGYYDKPSTNNVVRHPAANRNAPQPVTVHKSPILPPVPPASSCLPDEVEDDLSEITIQFDDGVQTLYVGPVEIVDKGDGGGGGNASPQAAASNPPSLGKDGGRNGAKEENVTIRGSGEGVRARERFQEERAIVTLEPQSLCIKQAPMLNFARAATSTIAPTNNANVVGSNRAVPPTAHLTVVPVASLRDDNHRSGNAINRVSVLRSPPQPIAVAAAPASKHQPPAATAATATATAAVPVPVSAPPPLHILTTIKQEPDVAPELVDDGNHTLPNEGNSGELLQETTTLVEEKPLLANVVSVAEDSTVGSVPTSNGGAASCDAAVMTAASVITNTSATQTLLEEDISGGTTAAVVISAELAKSAKDQASSTNVVQQEVFEQQVVPEANLNAAVHDPADDVQPVVGTEPAAIVEHKAHQQVVAAEVLPDASPSSDVTATQLQIPPPPPKRGRGRPPKVPKIPPSPEVASVNAAASNGSPSPVKSYISVSALFKPKSKRSRNVEEASAATIVSEEEIQKKTEGNEVTTIGCDVEGKSLSNGEGEGKATNVPKEVKVRSPASLKAKEIESVLEEPTASVGKQLESSSAVVKEAEKESSPGCDSGIESVSDSTTTVKKHPTRGRPKSSLSAASEEDRDRIPSVASKEKENGDGKKRRSGSSVPKPTVQHSGTRDEEEEDDDDDEDEQQPLKGLKKRTVRTSRKPSAKAKEAAEAAEVAQSVALSFGDEIQCCKCDMSFKTEAWYRKHLMNAHELDLSQAVQLLSSLVAERGTDEEVPTLEPTPPSGDGEINGAIETEPVKADDGGSPKDKTSEHNRGTKVSKKESLSPLASSSASSRKRSKSTISSEDGGSAKRVAVETGSNRKQPATVQQNGVCKKEIKVEQPPQRTPFQRNDDDASMEEQNGEVEGSQQTPLMDDSATPLETKPQTKQERYEPYDPYEGDPEKLSPFEEAKVIVLESDTDGGGSMLFKCTICDGQFTDIPAIKEHLSTVHAAIKRRSCEHCGRTFVQTGDLTRHVRIHTGHRPFKCPFPNCTYAFISSGDLYKHVRRHNADVALPKPHACDQCGKDFERSYDLKRHKTMHLKQQPGFTGITCEVCGKVFARKDQYRAHTYRHMGVRPYQCEVCGKAFTDPSNYSKHARLHELDGIEVVCDFCGRPFKNKSAISKHIFHCQQKKMRRMAAKVEKGGEGDDGGSSKTRRVGVAAGGGFGKSEDTGALVEAPLKLKQEPQARKQRNGGKNGSKRKRRRRARSETPQSSSASXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRSVKQRNRRSNYKNGVTFEATTPS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -