Asin002629.1
Basic Information
- Insect
- Anopheles sinensis
- Gene Symbol
- -
- Assembly
- GCA_000441895.2
- Location
- KE525342.1:2219345-2228444[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.0086 0.61 10.5 0.2 1 23 972 994 972 994 0.98 2 12 0.0011 0.075 13.3 2.0 3 23 998 1018 997 1018 0.95 3 12 0.0004 0.028 14.7 0.8 3 23 1026 1046 1025 1046 0.99 4 12 0.00086 0.061 13.6 4.4 2 23 1053 1075 1052 1075 0.95 5 12 0.0037 0.27 11.6 0.1 1 23 1085 1107 1085 1107 0.98 6 12 2.8e-05 0.002 18.3 1.8 2 23 1113 1135 1112 1135 0.95 7 12 0.0058 0.41 11.0 0.3 3 23 1149 1168 1148 1168 0.97 8 12 0.00011 0.0082 16.4 2.8 1 20 1175 1194 1175 1197 0.92 9 12 0.0019 0.14 12.5 0.1 1 23 1205 1227 1205 1227 0.97 10 12 2.2e-05 0.0015 18.6 3.6 1 23 1233 1255 1233 1255 0.98 11 12 0.00018 0.013 15.8 6.7 1 23 1261 1283 1261 1283 0.98 12 12 0.00077 0.055 13.8 4.2 1 23 1289 1311 1289 1312 0.95
Sequence Information
- Coding Sequence
- ATGAATGCAGAAACAGAATGCCCGGTCTGCACCCTCTACTTGAGGGCAGGCATAAGCCTAGAGGAACATTTGGACACCCACCCGAAGGACCAGCTTATTAAAGTGCTGGCCACAAGAGCACGCCCAGCGATTCAGACCTTGCCGCAGACGGCACCGGTGCTGCTAACTACACCCACAACCCCCGTAGTCGCTCCCCTGCCGACCCCGACCCCCGCCGCAGTGCCAGCAAGCGCACCGGCAGCAATCGAGACCGCACCGGCGGCAAGCTACAATTTCCCCAATATAATGATAACCCCGCTCAGATCACTATCAGATGTCGCACGAGCATACCAGCCGCGCTATACAAACGAGCGATATTCTGGACCGCCTCCTCCATATAGTCGGGCCACCCAGGTACAATCCGGCACTCCCACAGCCACTCAGGCAGCAGCGCCCACCGAACACACCGTCGAGGCTGGACCCTCTGGGTTAGCGCGAGCGAAACCCTGCTTGGTCGAGGAGGATGTACTATCAAAAATTCTTGATACGGAATGTAGTGCGCCGTGGAAGACATCCTACGGTTTCGAGATCGGTAGCCAACATCGAGCGGTAACGATTGAGCGGAGCCAGCGGGGCAACACCACCACCACCACCACCACCACCACCGAGGAGGTGTTGATGCGGTTGCCCCGTAAAAAGACACAGCCACAGATCATAACCGTGAGAGATAGTAGCGCTAGCACTACCTCGTCGGAGGGTATGAATTCCCCACGGAAACCCAGCGTGACCGTGCTAAGCGACGTAAAGCTCCGCAGCGCTACGGGCGACGACCCGGCACCGTCGACGCCGTCGGTACGTCAGGTGCGCGCCTCGGGCTTGCAACGCCACGATGGGAAGCGGGCACGCATCAACGCCGGGGAAGGCCAACCAACGGCCAGTACGGGAGGGGGGTTGGGGCTGGAGACTAGTCCGGAAACCGAGGACGGTTCTCGCTACTTTTCCGGGAATGAGATGAAGCGGGGGCGTCAGAAACGCGGGAGGCCTGGCCTACTGAAACCTACGAGTGCCCTGGCCGCTGCCAACATACCGCCTCCCTCGCAGCAGCAGCAGCAGCTTGTAAAGCTGGAACCGAGTGCGAAGGGGGAACCGCCGGCCGTTTACCAGGCGATGGTCGAGCAGGAGCCACCGCTGCTACCGCGTGCGTCCCTCGAGTGCTTCGAGATGGTGGACGCGACCGCGATGGTCGAGGTCGAGGTGGAGACGGAGGATCTTGTCGACCGGAAGCCGACGGAGAGTATGCTCTCGCAGGATGCACTGCTGTACGCCGAAGATCGCACGATGTCTTCGTCCATTTCGTCGTTTGCCGAGCTGTGTGAGATGAACGCGATGCATGCAGCCACGACACCGGTCAAAATCGAAGGCATGCTGTTCCAAGCGCACCAGCAGCAGCCAGCCTCGGTAGAGACGCCGGTGGCCACCGTCACCCCCACAACGCCACCGCCCGTCGCTGGCGACGACGTTATCGTAGAGACGCACCCACGCACGCCACCGGCTGCCTCCATCGAGCCGCAACGCGACGTAAAGGATTTCCTCGACGTCTGCGGACCGTCGACGTCGAAGTTTACCGCCAGTGCGTCTGCCGGTGCCGGTGGTGTTGTCCACCGTCCCTCGACGTACTATCGGCAGAGCTATGACGTCAAGGATTTTCTCGAAGCCGGTCCATCGTCGCGTGGGGCACCGTGTGAGAGTGTCATCGGGCCGATCGTGGCGTCGGACGGCGACCACCGACAACAGCAGCACCCCTTCCAGCTCTACAGCCACGCCGAGGTCGACTATGGCGCCGGCGAGCTCCACCGCGCCCTATCCACCCACTCAGCCTTTACCAGCGGTGCCTCGTCGCCGGACAACAGCGAGGCGGTCCCGGGCGTGTGGGCGCACCGTTTCAGTCCGCAGTACAGCAGTGCGGCGCTGGCGGCGAATGGCGAGCTGCTCGGCACTGCCGACCGGAGCGCCAGTGCCAGCCCTATTGGGGCCAATCGGGGTGGTGGTGGTGCGGGCATCAAGCCGGTGGTGAACAACGCGGCCACCAACTCCACCAGCCGCCATTCGTCGTCCGCCATGTCGCTGGCCTCCTCCATCGTCTCGTGCAGCATGGAGCGGGCACCGTCCACCGAAAGCCTCAACATACGCACCGACGAGAAGATGCCAGCGAAGGGGGAAATATCCGAGCAGGAGAGCAACGGGGATATGGAGTTGACGCCTTGGAAACGGCTGTGTGCCGTAAGCGAAAACATCCCAGTTTATCCGAGCTCGTACGACTACTCGACGGCACAGGAATGCTGGAACCTGAGCAACCGCAGCCTGGGCAACCATAGCGGGGCAATTTCCGGTGAATCAAATGGACCGCCGTCGTACAACTCGCTCGGCCATACATATTTGCCGACCCGGATGGCATTCCCGTTTTCGTCCGGCTCACAGGCGTCCCTGTCCAACTATCCGTCGCGAGGTCCCGTGGGAGGGTATAAAAAAGAGTTCGTTGGTGACGAGGACGAAGACGACTATGATGAGGATGATGCGGCGGGCGAAGGCGAGGACGAGGAGGCACGAGAGCGCAGTGGGTCCATGAAAAGCACCATACCGAAGGTGCCATTTGGGGAGCTGGGTGGTAATCTCGAACTGCAGCTTCAGCAGCATCAGCAGGCAATGGATCAACCAGCTACGCTCGTACCGTACGTGGAGGGGCCGGGTCTGCTGACGGAGGATGTAAAGACGGGCGTTGCCGGGGAGAAGCCTCCGACCGAGCCGCTCGTCCCGGTGGTGATGGACTACGACTGGCTGCGGCAGGAGATACAGCGCAAGTACGAGCTCGGGGCGCAACCGTCGAGCACGATGGTGCTCCTGACGCCCACCACGACGGTGGTGCGCAAGCGGCTGTTCGTGTGCGCGGTGTGTCGGGCCGAGTTCGAGCGCTTCAACCAGTTCAACGCCCACCTGATGGTGCATCCGGCCGAGTGTTTGGCGTGCGGGCGCCACTTCAAGCAGTGGCGCAACTTCGCCCTGCACCTGAAGCGCCACCTCGGCATCAAGGAGCACGGCTGTCGGGTGTGCGGGAAGCACTTCGTGATCAAGCAGAAGCTGATCGAGCACATGCGCGTCCACTCGGGGCACGCACCGATCCGGTGCAAGCTGTGCAACCGGCACTTCAAGCGCTTCTCCAACCTGGCGCAGCACAGCAACCGCTACCATCTCAACAAGGTGGCGGTGAAGCACGAGTACGTGTGCTCGCAGTGCGGCGACGTGTTTCCCACCCGCGCCAAGATGGAGTGGCACAAGGAGACGCACGAGCAGCGGCCGAAACCGTGCCCGTACTGCCGGGAGAAGTTCATCCACCAGAACAGCCTGACGCGCCACATCCGGCTGTCGCACACGCTGCAGTACGCGAAGCTGAAGAACAAGACGGAACCGTGCACCGTCTGCCAGCAGCCGTACACCAAGGCGAGCATGCGGCGCCACATGGAGACGCACACCGAGGAGCGGCTGGTGTTCTCGTGCGGCATCTGCAACAAGCACTTCACCACCAACTGGAACCTGAAGCAGCACAAGTGGACGCACGCCAACCCCACGATGAAGCCGTTCCAGTGCACGCTCTGCCCGGCCGGCTTCGTGCGCGAGTCGGACTACCTCACGCACGTGAACGCGCACCGTTCGATACGGCCGTACACGTGCAACCACTGCGGGCGCCAGTTCATCCGCAAGTACAACTGGCTGCGGCACTCGCGCGAGCACGAGACGGACAAGAGCCACAAGTGCGACGAGTGCGGGCGCCAGTTCCACCGGAAGTACTACCTGACCGAGCACAAGCGGATGCACTCCGGCGAGCGGCCGTACGCGTGCAACATCTGCGGCAAGACGTCCTCCACCAAGACCAACCACAACAAGCACGTGCGCATCCATCACGCGCGCGATCCCCTGACGGCGGAAGGCTAA
- Protein Sequence
- MNAETECPVCTLYLRAGISLEEHLDTHPKDQLIKVLATRARPAIQTLPQTAPVLLTTPTTPVVAPLPTPTPAAVPASAPAAIETAPAASYNFPNIMITPLRSLSDVARAYQPRYTNERYSGPPPPYSRATQVQSGTPTATQAAAPTEHTVEAGPSGLARAKPCLVEEDVLSKILDTECSAPWKTSYGFEIGSQHRAVTIERSQRGNTTTTTTTTTEEVLMRLPRKKTQPQIITVRDSSASTTSSEGMNSPRKPSVTVLSDVKLRSATGDDPAPSTPSVRQVRASGLQRHDGKRARINAGEGQPTASTGGGLGLETSPETEDGSRYFSGNEMKRGRQKRGRPGLLKPTSALAAANIPPPSQQQQQLVKLEPSAKGEPPAVYQAMVEQEPPLLPRASLECFEMVDATAMVEVEVETEDLVDRKPTESMLSQDALLYAEDRTMSSSISSFAELCEMNAMHAATTPVKIEGMLFQAHQQQPASVETPVATVTPTTPPPVAGDDVIVETHPRTPPAASIEPQRDVKDFLDVCGPSTSKFTASASAGAGGVVHRPSTYYRQSYDVKDFLEAGPSSRGAPCESVIGPIVASDGDHRQQQHPFQLYSHAEVDYGAGELHRALSTHSAFTSGASSPDNSEAVPGVWAHRFSPQYSSAALAANGELLGTADRSASASPIGANRGGGGAGIKPVVNNAATNSTSRHSSSAMSLASSIVSCSMERAPSTESLNIRTDEKMPAKGEISEQESNGDMELTPWKRLCAVSENIPVYPSSYDYSTAQECWNLSNRSLGNHSGAISGESNGPPSYNSLGHTYLPTRMAFPFSSGSQASLSNYPSRGPVGGYKKEFVGDEDEDDYDEDDAAGEGEDEEARERSGSMKSTIPKVPFGELGGNLELQLQQHQQAMDQPATLVPYVEGPGLLTEDVKTGVAGEKPPTEPLVPVVMDYDWLRQEIQRKYELGAQPSSTMVLLTPTTTVVRKRLFVCAVCRAEFERFNQFNAHLMVHPAECLACGRHFKQWRNFALHLKRHLGIKEHGCRVCGKHFVIKQKLIEHMRVHSGHAPIRCKLCNRHFKRFSNLAQHSNRYHLNKVAVKHEYVCSQCGDVFPTRAKMEWHKETHEQRPKPCPYCREKFIHQNSLTRHIRLSHTLQYAKLKNKTEPCTVCQQPYTKASMRRHMETHTEERLVFSCGICNKHFTTNWNLKQHKWTHANPTMKPFQCTLCPAGFVRESDYLTHVNAHRSIRPYTCNHCGRQFIRKYNWLRHSREHETDKSHKCDECGRQFHRKYYLTEHKRMHSGERPYACNICGKTSSTKTNHNKHVRIHHARDPLTAEG
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -