Asin011170.1
Basic Information
- Insect
- Anopheles sinensis
- Gene Symbol
- -
- Assembly
- GCA_000441895.2
- Location
- KE525278.1:320609-323555[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 18 2.4 1.7e+02 2.7 1.7 2 23 2 24 1 24 0.88 2 18 0.074 5.3 7.5 0.4 6 23 33 50 33 50 0.97 3 18 4.7e-06 0.00033 20.7 0.8 2 23 57 79 56 79 0.95 4 18 0.0047 0.33 11.3 6.3 1 23 87 109 87 109 0.98 5 18 4.7e-05 0.0033 17.6 0.3 2 23 113 135 112 135 0.95 6 18 0.00035 0.025 14.8 0.5 2 23 142 163 141 163 0.95 7 18 0.15 11 6.5 1.3 2 23 173 195 172 195 0.94 8 18 0.033 2.4 8.6 1.0 1 23 202 225 202 225 0.96 9 18 1.2 86 3.7 1.2 2 23 400 422 399 422 0.89 10 18 0.87 62 4.2 1.1 6 20 431 445 431 448 0.94 11 18 3e-05 0.0021 18.2 0.4 2 23 455 477 454 477 0.93 12 18 0.0081 0.58 10.5 9.1 1 23 485 507 485 507 0.97 13 18 3.6e-05 0.0025 18.0 0.5 2 23 511 533 510 533 0.97 14 18 8.5e-05 0.0061 16.8 1.2 1 23 539 561 539 561 0.96 15 18 0.065 4.6 7.7 2.1 2 23 571 593 571 593 0.96 16 18 0.00013 0.0095 16.2 1.9 1 23 600 623 600 623 0.97 17 18 4.8e-06 0.00034 20.7 0.4 1 23 628 650 628 650 0.95 18 18 0.00028 0.02 15.1 2.7 1 23 656 679 656 679 0.97
Sequence Information
- Coding Sequence
- ATGAAATGTGAGATTTGTGGCCAGCAGCAAGATTCCTTTACGACGCTCAAAATTCACTACCATCAACAGCACAACGTCCGGGGATACATCAAGTGCTGTGGTCGTATGTTCAACAGCCGGTACCGGCTATTAGAGCACCTTTCGTATCACGTTGGTGCCAGTATGGTACGGTGTGAAATTTGCGATAAGACCTTTAGCAGCCGAACCTACCTTCAGGTGCATAAAAGTCGTGTGCATGGTCGGGCGGAAGATCGACCGTTCAAGTGCACACAGTGCCACCAATCGTACGCAATGGAATGCCACCTGAAGGCGCACATGGTTTCACACGTCCGGGTAACCTGCTCCATTTGCGGCAAGGAGCTGTCCAGCAGCTTTTCGCTCCGAACGCACATGATCAACATGCATGGGAACCGAGAAAATCTCATTTGCGACAGTTGCGGAAAGGAATTTCGCACTCGCCAGGCATTCGATCGACATGTTAAGTTGCACATGGGTGTTGACGTAACGGAGCAGTTGCAGTGCTCGCTGTGTTCCAAGTGGCTTACCAGTAAGCGAGCGTTGAAGGTGCACGTCAAGCATGTGCACACCGAGGCAGGGCAAACGTTCAAATGCGACCTCTGTGCCCAGGAATGTCCCAACAGTCGTGCTCTATCCAACCATAAGTTACGCGTCCACGTTGAGGAACGGTTTGAGTGCGAGATAACTTCAGATGATTCTTTCCCTTCGCTAGTCTGTTCAGAATGTGAAGGGAAAGTTGACCAGTTTCATGTCTACCAAGAAGAAGTGAAACAAAATCAAGATCGTTTGTGGTCCTCCAAGCTGCAAGAATGTATCGGTGAAACGACGATCGAGCATGCTCCCAATTCGGAACACGAGGAGCTCATGGTATCCATTCCAAAAACTGAGAAAATCGAAGCAGCAGATAACAATTCGTTGCAAACGCCGGAAGATTCTGATGCAAGCATTGGAGACATAGATGATCCTGAGAATGAACCATTGAGTACTAGCGAGGAAATCAAAACGGATTATAATAAGTCCAAGAAAACTTACGCACCGTTACGAAAGCAGACAAAGGTTCGAAAGAACGTTAGATTACGTGACGTTGAAAACAAGAAGGAACCGAGGGATGGTGTGGGACGCAAGAAATTCAACCACCTAGACGAAAAAAATCGAAGGCTGCAGGAGTTCTACGACATGAAATGTGAAATTTGTGGCGAGCAGCAAGTTTCTTTTACGACGCTCAAAATTCACTACCATCAACAGCATAACGTCCGGGGATACATCAAATGCTGTGGTCGTATGTTCAACAGCCGGTACCGGCTATTAGAGCACCTTTCGTGCCACGTTGGCGCCAGTATGGTACGGTGTGAAATTTGCGAGAAGACCTTTAGCTCCCGAAGTTACTTACTAGTGCACAATAGTCGTGTGCATGGTCGGGCGGAAGATCGACCGTTCAAGTGCACACAGTGCCACCAATCGTACGCACACGAGTGCCACTTGAAGGCGCACATGGTTTACCACGTTCGGGTAAGGTGCTCCATATGCGGCAAGGAGCTATCAAGCAGCCTTTCACTACAGTCGCATATGAAACGCATGCATGGGGATGTTGAAAAGCATATTTGTGAGACGTGTGGGAAAGAATTTCGATCCCGTCCGGCGTTCAATCAACACGTTAAGTTGCACATGGGCACCGTCGTGGTGGAACAGGCTCAGTGTACGATTTGTTCCAAATGGCTTAACAGCAAACGTGCTCTGAAGCAGCACATCAAGCATGTACACGACGAAGCAGGAAAGCCGTTCAAGTGCGACCAGTGTGGGCAGGAATTCATACATAGCCGATCGCTATCAGATCACAAGATGCGCGTACATGTAGAGGAGCGCTACGAATGTGAAGTATGTGGAAAGCGTTTTAAACGGAGTATCTATTTGAAAGAACACAGTGCGATTCATTCTGGACAGCCTCTCTATTCGTGTGATATCTGCGATGCCACGTTCAACTCGAAATCGAATAAATATTCTCATCGCAAAAAGAAGCATCCTGTCGAATGGGAAGCACGCCGTAGGGAACAGTTGACAGCAAATACAAAAATACTCATACCTCCAGACTAA
- Protein Sequence
- MKCEICGQQQDSFTTLKIHYHQQHNVRGYIKCCGRMFNSRYRLLEHLSYHVGASMVRCEICDKTFSSRTYLQVHKSRVHGRAEDRPFKCTQCHQSYAMECHLKAHMVSHVRVTCSICGKELSSSFSLRTHMINMHGNRENLICDSCGKEFRTRQAFDRHVKLHMGVDVTEQLQCSLCSKWLTSKRALKVHVKHVHTEAGQTFKCDLCAQECPNSRALSNHKLRVHVEERFECEITSDDSFPSLVCSECEGKVDQFHVYQEEVKQNQDRLWSSKLQECIGETTIEHAPNSEHEELMVSIPKTEKIEAADNNSLQTPEDSDASIGDIDDPENEPLSTSEEIKTDYNKSKKTYAPLRKQTKVRKNVRLRDVENKKEPRDGVGRKKFNHLDEKNRRLQEFYDMKCEICGEQQVSFTTLKIHYHQQHNVRGYIKCCGRMFNSRYRLLEHLSCHVGASMVRCEICEKTFSSRSYLLVHNSRVHGRAEDRPFKCTQCHQSYAHECHLKAHMVYHVRVRCSICGKELSSSLSLQSHMKRMHGDVEKHICETCGKEFRSRPAFNQHVKLHMGTVVVEQAQCTICSKWLNSKRALKQHIKHVHDEAGKPFKCDQCGQEFIHSRSLSDHKMRVHVEERYECEVCGKRFKRSIYLKEHSAIHSGQPLYSCDICDATFNSKSNKYSHRKKKHPVEWEARRREQLTANTKILIPPD
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -