Asin007740.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles sinensis
Gene Symbol
-
Assembly
GCA_000441895.2
Location
KE525266.1:523648-533573[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 3.5e-06 0.00025 21.1 1.4 1 23 178 201 178 201 0.97
2 10 8.7e-07 6.2e-05 23.0 2.1 2 23 208 229 207 229 0.98
3 10 2.3e-05 0.0017 18.5 0.4 1 23 235 257 235 257 0.96
4 10 1.3e-05 0.00089 19.4 1.3 1 23 263 285 263 285 0.98
5 10 3.5e-07 2.5e-05 24.3 5.9 1 23 291 313 291 313 0.98
6 10 2.8e-06 0.0002 21.4 4.9 1 23 319 341 319 341 0.99
7 10 1.3e-06 9.5e-05 22.4 1.3 1 23 347 369 347 369 0.98
8 10 0.0014 0.1 12.9 3.4 1 23 375 397 375 397 0.96
9 10 0.0037 0.26 11.6 0.0 2 23 423 445 422 445 0.95
10 10 0.00046 0.033 14.5 1.7 1 23 458 480 458 480 0.97

Sequence Information

Coding Sequence
ATGAATTCACTCGTTATTGTGTGCGTACCGCATTCGGTTGAGTACACACCTGCTGTACAGTTTTCCTCCCTGGAGTATGTAACCGTTTCGGTGGGGGATTTTGAACAGCTCGATGCGGAGGGTTCAGGCAATACCAGCTCAATCACAGCTTCCAAGCCGTTGGATATCGAAGGAACGCCGGTGGACACAATTCTACGCGATGATTTGCTATCACGAAACAGTGTTAGAAAACAGATCCGCAGCAATCTCTCAATCGTGGATGCATCCCAGGAAAGCGTATCCGGTGAGGACGAAAACCTGTCAGTGCTAGATTACAACATTAACCCGTCCAAATACGCTGCTATAAGCAATGATATCATTTTGGAAGAATCTTCCTCGAGTCTGGACGAGGGGATTGGACTTAGTAACACGGAAGACTCGGGTGACGACCAGAGGAAAGTCCCTTCGAACACGGCAAAATCTCATTCACTGTCAGATCCGAAGAGCGGCAGTGTGAGTGGTCGCTCCAGGAAGGTCGCTGGGAGGAAAATCTATCGTTGTGAAATCTGTGACGAGCAGTTTCCGAAGAAGAAACATCTCCGGGCGCATCAAGCTAAGGAGCATCCGGGCGAACACTGCAACAAATGCGCAATATGCCAGAAAACATTCAAACTTCGCTCCAACCTTCGGCAGCACCAGCGGATTCACACCGGCGAGCGACCCTTCCACTGTGGTGTATGTGGGAAAACCTTCGTCCAGGGTAGTGCACTTACCGTGCACCGGGAACTGCACAAGGAGCAGCGGGACTACGAGTGTGCGGTTTGCCAAAAGGCGTTCAAGTCCAAGTTCGCCTTCAAGAAGCACGAAAAGGTGCACACGGGCTTGCGGCCGTTCAAGTGCGAAGTTTGCGGCAAATGTTTTACCCAATCGTGCAATCTGAAGGCGCATCAGAAACTGCACACGGGCAACCACGCCTACCAGTGTCCGACGTGTTCTAAGACGTTCCGCTTCAAGTCGCACTACCAAGATCACCTGCTGACGCACACGAAGGAGAAAAAGTACAGCTGTACCCAGTGTGGACGCACTTTTGCCTACAAGAATTCCTACCAAAGGCACATTCTAATCCACCGGGACGAAACTCAGCATCCGTGCACGGTCTGTGGGAAGCAGTTCGCCAAGCTGAGTCATCTGGCATTTCACCGTAAGTCTCACGGTTCCGCTAGGGTTGTGGTCACTGCCGCCACCGATGGGGTACAGGGAGCTGGTACCGTGAAGGACGACTGGCTGACTTGCAATATTTGTGGCTTCGTCCTGGAAAGCAGCGAAGGGATGTTGGCTCATCAGAGGGAAGTTCACGCGACCGGCGGTGAGAGCGGCGAGGCAAGGTGTCGGTACAAGTGCGTTATCTGCAGCAAATCGTTCCAGGAGGAGAAAGAATTGCGTACCCATTTCAAGCTCCACGAGGCCGACGATTGTCCCTTCCAGTGCGGGATGTGTGGTATTCTCAATCTAGCTCATACCTAG
Protein Sequence
MNSLVIVCVPHSVEYTPAVQFSSLEYVTVSVGDFEQLDAEGSGNTSSITASKPLDIEGTPVDTILRDDLLSRNSVRKQIRSNLSIVDASQESVSGEDENLSVLDYNINPSKYAAISNDIILEESSSSLDEGIGLSNTEDSGDDQRKVPSNTAKSHSLSDPKSGSVSGRSRKVAGRKIYRCEICDEQFPKKKHLRAHQAKEHPGEHCNKCAICQKTFKLRSNLRQHQRIHTGERPFHCGVCGKTFVQGSALTVHRELHKEQRDYECAVCQKAFKSKFAFKKHEKVHTGLRPFKCEVCGKCFTQSCNLKAHQKLHTGNHAYQCPTCSKTFRFKSHYQDHLLTHTKEKKYSCTQCGRTFAYKNSYQRHILIHRDETQHPCTVCGKQFAKLSHLAFHRKSHGSARVVVTAATDGVQGAGTVKDDWLTCNICGFVLESSEGMLAHQREVHATGGESGEARCRYKCVICSKSFQEEKELRTHFKLHEADDCPFQCGMCGILNLAHT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00096538;
90% Identity
iTF_00096538;
80% Identity
-