Asin011153.1
Basic Information
- Insect
- Anopheles sinensis
- Gene Symbol
- -
- Assembly
- GCA_000441895.2
- Location
- KE525278.1:313803-317208[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 17 0.0073 0.52 10.7 5.3 1 23 194 216 194 216 0.96 2 17 0.64 45 4.6 0.1 2 15 220 232 219 241 0.73 3 17 0.93 66 4.1 0.5 3 23 276 298 274 298 0.82 4 17 3.8e-07 2.7e-05 24.2 1.0 1 23 328 351 328 351 0.97 5 17 0.0024 0.17 12.2 5.1 1 23 360 382 360 382 0.98 6 17 3.5e-05 0.0025 18.0 0.3 2 23 386 407 385 407 0.94 7 17 1.5 1.1e+02 3.4 0.1 2 23 441 467 440 467 0.88 8 17 2e-06 0.00014 21.9 2.3 1 23 497 520 497 520 0.94 9 17 3.9e-06 0.00027 21.0 0.8 1 23 530 552 530 552 0.98 10 17 0.016 1.1 9.6 0.1 2 23 558 579 557 579 0.95 11 17 2.1e-05 0.0015 18.7 2.1 2 23 587 608 586 608 0.96 12 17 0.01 0.72 10.2 0.8 2 23 623 645 623 645 0.94 13 17 7.7e-05 0.0054 16.9 0.7 2 23 652 673 651 673 0.98 14 17 2.1 1.5e+02 3.0 2.4 2 21 682 701 681 704 0.93 15 17 0.016 1.1 9.6 0.4 1 23 711 734 711 734 0.97 16 17 2.9e-06 0.0002 21.4 0.5 2 23 744 765 743 765 0.96 17 17 2.4e-05 0.0017 18.5 3.9 1 23 771 794 771 794 0.98
Sequence Information
- Coding Sequence
- ATGGAGGTACAATGTCGATTGTGCCTCGGTCAAGCGTCTGCAAAACTTGTGCTGTTTTTGTCGAACGAAGAACTGCGTCTAATGGTGGATAGTGTATTTAACTTCAAGATCATATCCGATCCCCGTTTAACAGAATCCGTTTGCCTGCAATGCTCGTCCACCGTACAGGAATTTTATCAGTACAGTAAAAAGGTGCGCACCAATCAAGAACTTCTGGAAGAAGAACACTTGGTTCAATCAGCTAATTTGTATGAAAAATTAGACTTTGAAAACGTACTAATCGACGACACATCTTGTGAGAATACAAATAATGAATCGAACTGTGCAGCAGATCACCCAGTCAAGGAGCCCCACGAGACCAACGCTGAGATTACGATACTCTACGGTGATTTAGACGAAACATTTGCTGCTCACGAAGTCCGAAGGAGTAATGATACCGTTACAATCAACCGCAACCCATCGAATGGCAACTCGCCTAAGATCCAAGAATTTGAAATCTATGATGATGATACTTCCGAGGTAAAACACTTTGAGCAAGCGCAAGAGCCAGCGAGTAGTGTGAAACTCGAAGACAGATTTCATCGTTGTGAGTTGTGCGATCGATTGTTTAGTAACAGCTTGCATTTCAAAACGCACCAGAGTGAACACCGGAAAAAAGAATGCCCTATATGTGGGAAAAATGTAAACGCCAAATACCTTCCGATGCATATCGCTGATATGCACCAGACAAAACCAGCAGCGAGCAAGAAGCGGCACGAGAAAGTTCAGCTTCCAGCGAGCCAGTACGAGCGTGACCGTATGATTGATCTGTTCATAGGGATTCGCTGTGAGCTGTGCCAGTTCGGGATCTATAAAACCTTTGCCGATCTACAGATGCATTATCGTACGAAGCACGGTGTACAGGGTTACGTGCGTTGTTGTGGAGACAAGCTCGTTACACAAAGTGCTGCCGCGGAACACGTCCTGGTCCATCAGGGTGCATTTGCTTGTAAGTATTGCGATAAAACGTTCGTTTCCAAGCGAGGTTTAATCAAACACATGGCTACTAAGCATGATGAAAAAGCTGAAAGTCGAGTTTTCCGCTGCCGTTTGTGCAACATAACTTTCACCAGCGAAGAGAAGTTTATTCATCACAGGAAGAAGCACGAAAGAAAAGAATGTCCCATTTGTGGAAAGACTGTCCGGAAAAGTTACCTGAAGAAGCACATTCAGGATGTACACGCGGACCCTTCGAAAAATGGAGAAGACTCTTCGTCCACGGAACGGCGGACAAAACAAAGTACCATTTACGATCAAATGATTTTGGATAATTTGGGATTGCGTTGCGAGCTGTGTCCACCAGAGGCGGCCCAAGACTTCGATCAGTTCAATAGCTTGCGCACTCACTACAGTACGGAACATAACATGCGTGGATACGTGCGTTGCTGTGGAAAGCAATTTTTCATCCGTTGCCTGGCAGTACAACACATAGCAGCCCACAAAGGCATCCATCGTTGCCAGCTGTGTGATAAAACGTTCAGCACTCGAACCAGCTTGAAGAACCATATGGGCATCATTCATGCCTCGGACAACCCTGAGGATCGCTCTTACGATTGCGACGAGTGTGATAGCTCCTTTTCTACCAAACCGCAGCTAAGGGTGCATCAGAAGCGCCATAAGCTCACGCAAACCGAATGTGCACTCTGCGGCAAGAGCGTCCGATCGGACTACATCCAGAAGCACATTGCAACGCAGCATGGCGAGAAGTGCAGGCAGCTGATATGCCATGTTTGTGGCAAGGCGTTCTCTACGGAGTGTGTATTGAAAGCGCACATGAAGCAGCATCTGGAGCCGCATGCCGTTCAACGAGTAAAACCCGAGCGAGCGGAGTGTGCTGTGTGTAAAAAGATGATACGGGGCAAGTACAGCATGAAGAAACACATGAAAGATATGCACAGCGCGGCGAGCAACCAGCAATGTAGCGTTTGCGGCAAATTTATACGCTCGTCAACCGCCATGAAGCAGCACATGCGTATCCATCAGGGCAGCGGCATGGAAAAGCTTCAATGCCCGTTCTGCTTCAAATGGGTCAAGGGCAAGACCTATCTCAGGAAGCACATTCAATGTTTGCACGAAGAAAAGGGGCAACTGTTTCGATGCGACGTGTGCCAGCATGAGAGTCCCAACAGCCAGGCACTGGCTGCGCACAAGCAACGTGTCCACGAGTTTGTGGAAAGTGGAGATAAGCTAAAATGCGAATACTGTGGGAAAAATTTCAAGCGTTCGATATATCTGCGAGAGCACATCGCGCTGCACACCGGTGAGCAGCTATATACGTGCGAGTTTTGCGGTAAAAAGTTCAAATCAAATGCTAATTACTACTCGCACCGGAAAAAGAACCATTCGGAGGAGCTGCAGGGGAAAAATGAAACCGAAACTAATGGGCAGTAG
- Protein Sequence
- MEVQCRLCLGQASAKLVLFLSNEELRLMVDSVFNFKIISDPRLTESVCLQCSSTVQEFYQYSKKVRTNQELLEEEHLVQSANLYEKLDFENVLIDDTSCENTNNESNCAADHPVKEPHETNAEITILYGDLDETFAAHEVRRSNDTVTINRNPSNGNSPKIQEFEIYDDDTSEVKHFEQAQEPASSVKLEDRFHRCELCDRLFSNSLHFKTHQSEHRKKECPICGKNVNAKYLPMHIADMHQTKPAASKKRHEKVQLPASQYERDRMIDLFIGIRCELCQFGIYKTFADLQMHYRTKHGVQGYVRCCGDKLVTQSAAAEHVLVHQGAFACKYCDKTFVSKRGLIKHMATKHDEKAESRVFRCRLCNITFTSEEKFIHHRKKHERKECPICGKTVRKSYLKKHIQDVHADPSKNGEDSSSTERRTKQSTIYDQMILDNLGLRCELCPPEAAQDFDQFNSLRTHYSTEHNMRGYVRCCGKQFFIRCLAVQHIAAHKGIHRCQLCDKTFSTRTSLKNHMGIIHASDNPEDRSYDCDECDSSFSTKPQLRVHQKRHKLTQTECALCGKSVRSDYIQKHIATQHGEKCRQLICHVCGKAFSTECVLKAHMKQHLEPHAVQRVKPERAECAVCKKMIRGKYSMKKHMKDMHSAASNQQCSVCGKFIRSSTAMKQHMRIHQGSGMEKLQCPFCFKWVKGKTYLRKHIQCLHEEKGQLFRCDVCQHESPNSQALAAHKQRVHEFVESGDKLKCEYCGKNFKRSIYLREHIALHTGEQLYTCEFCGKKFKSNANYYSHRKKNHSEELQGKNETETNGQ
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -