Basic Information

Insect: Anopheles sinensis
Gene Symbol: -
Assembly: GCA_000441895.2
Location: KE524591.1:20879-30585[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 21 0.21 15 6.1 7.6 1 23 792 815 792 815 0.96

2 21 9.3e-05 0.0066 16.6 7.3 1 23 821 843 821 843 0.99

3 21 0.11 7.5 7.0 1.0 2 23 893 914 892 914 0.95

4 21 0.00026 0.019 15.2 0.9 2 23 919 940 918 940 0.97

5 21 0.00083 0.059 13.7 0.1 1 23 967 990 967 990 0.95

6 21 0.014 1 9.8 0.5 1 23 1003 1025 1003 1025 0.98

7 21 2.6e-05 0.0019 18.4 1.4 1 23 1108 1130 1108 1130 0.98

8 21 0.00027 0.019 15.2 1.2 1 23 1225 1247 1225 1247 0.98

9 21 0.00034 0.024 14.9 3.4 1 23 1254 1276 1254 1276 0.98

10 21 1.5e-05 0.0011 19.1 2.3 1 23 1288 1311 1288 1311 0.98

11 21 2e-05 0.0014 18.8 1.0 1 23 1352 1374 1352 1374 0.98

12 21 3.8 2.7e+02 2.1 0.0 1 23 1388 1411 1388 1411 0.87

13 21 0.18 13 6.3 1.9 1 23 1491 1513 1491 1513 0.99

14 21 0.0011 0.076 13.3 0.5 1 23 1541 1563 1541 1563 0.98

15 21 0.0027 0.19 12.0 7.3 2 23 1600 1621 1599 1622 0.93

16 21 0.00028 0.02 15.2 3.5 1 23 1628 1650 1628 1650 0.96

17 21 0.0002 0.014 15.6 0.1 2 23 1717 1738 1716 1738 0.97

18 21 0.24 17 5.9 10.7 2 23 1767 1788 1767 1789 0.93

19 21 0.015 1.1 9.7 4.8 1 23 1795 1818 1795 1818 0.94

20 21 0.00011 0.0081 16.4 0.8 1 23 1896 1918 1896 1918 0.98

21 21 0.00027 0.019 15.2 0.7 2 23 1976 1997 1975 1997 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	21	0.21	15	6.1	7.6	1	23	792	815	792	815	0.96
2	21	9.3e-05	0.0066	16.6	7.3	1	23	821	843	821	843	0.99
3	21	0.11	7.5	7.0	1.0	2	23	893	914	892	914	0.95
4	21	0.00026	0.019	15.2	0.9	2	23	919	940	918	940	0.97
5	21	0.00083	0.059	13.7	0.1	1	23	967	990	967	990	0.95
6	21	0.014	1	9.8	0.5	1	23	1003	1025	1003	1025	0.98
7	21	2.6e-05	0.0019	18.4	1.4	1	23	1108	1130	1108	1130	0.98
8	21	0.00027	0.019	15.2	1.2	1	23	1225	1247	1225	1247	0.98
9	21	0.00034	0.024	14.9	3.4	1	23	1254	1276	1254	1276	0.98
10	21	1.5e-05	0.0011	19.1	2.3	1	23	1288	1311	1288	1311	0.98
11	21	2e-05	0.0014	18.8	1.0	1	23	1352	1374	1352	1374	0.98
12	21	3.8	2.7e+02	2.1	0.0	1	23	1388	1411	1388	1411	0.87
13	21	0.18	13	6.3	1.9	1	23	1491	1513	1491	1513	0.99
14	21	0.0011	0.076	13.3	0.5	1	23	1541	1563	1541	1563	0.98
15	21	0.0027	0.19	12.0	7.3	2	23	1600	1621	1599	1622	0.93
16	21	0.00028	0.02	15.2	3.5	1	23	1628	1650	1628	1650	0.96
17	21	0.0002	0.014	15.6	0.1	2	23	1717	1738	1716	1738	0.97
18	21	0.24	17	5.9	10.7	2	23	1767	1788	1767	1789	0.93
19	21	0.015	1.1	9.7	4.8	1	23	1795	1818	1795	1818	0.94
20	21	0.00011	0.0081	16.4	0.8	1	23	1896	1918	1896	1918	0.98
21	21	0.00027	0.019	15.2	0.7	2	23	1976	1997	1975	1997	0.96

Sequence Information

Coding Sequence: ATGGTGCCGCCGGCTTCAACGGTGAATCAGTATTCGGGGCGCACCAGCGAACCGCTGCCGGGTGCCGGCCAGGGAGGCGCCTACTTCCACACCGACCAGCTTGGCGCCGGTGCGATGGGACACTTCGGGGTGGGCGTGGAGACGGGTGCCGGTGGTGGATACTCCCCTGGCGTTGTCACCGGCGGTATGGTGCGCCCGGTCGGGCTTGGGGCGAGCCCGAACGCCACCTCCCCACCCGTTGGCGTCCCGGGAATGACAGGTGCCGGTGGAGCGGGTGCTGGCGGAGGGTATGGACACGCAACTTCCACTCCGACGCACGTGACCTCGTACATGCAGCAGACCGGTGGTTCACCGGGCGCTCTGCAGCGTATGAGCGCCGAGCTGAACGCGTCCCCGATGCAGCAGATGCAGGTGCCGGATCAGCACCGGCTCGTGGCGCCCATGGTGCACACGGAGTTTCCCACCGGCTCGAGCAGGGCATCATTTCCGCCCGCCGTCACACTACCCTCGGCGAGCCCGTGTGCACTGGCCGGCGATTCCATGGTTTCGATGCCGAAACCATCGGACATGACGCTGGCCAACAACGATCATCAGCTAAAGCAGGCGCAAATGTCGGTCATCACCCAGCAGCAATCGTCGGTGGCCGCAACCACCGCTGCCGGCTCCATGTACGGTATGCACGGGGTGGGGGGACCGATGGAAGCCCCGCTGGAGTCGGAATTTACCTTCCCCTCGGTCGATACCACCAACCCCAACGACGCTGTCCAGCAGCAGACACATCAATCGCAGCAGCAGTCCGGCATGTCGTTATCGATGGTGGGAAACAACGGCACCACGGCCACTAACAACACGGGAGGAATGGTCGCGCCAACGGGACGGGGAGACTCTACATCCGACCGCGTCACCCGCTCCAGCGCTCGCAATGTGTGCGCCGATGTGGCCGATCCCAACGAAGACGCCGACGCGCTGGTGGAAGTGATCCCGATGGATCCGCTCGCCACGACATCGGACGACAAAGCGGCGGACAGCGTAAAGGGCCTGCTGTCGAAGGGAAGGGACGATCCGTCGGAGAGGAAACAGCGGCCAGTCAAGCACGTGCGGTTTGTCGACGACGATAACTCGCTCGACGAGATGCCGCGCGCGCGTGGTAACGTTTCACCGCATCCGCTCGGCATGTCGCAAGGTGGACGGGGTGGGATGAGGGGAGGAAACGGTCCGCAGGAAGCCGACGAGGAGGACGACGATATGGATGGGCTGGCGCTGATGGAACACATACCGCCGGTGCAGAGTANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCACCGGAGCGACCCGGGGACGCGGTGGAGGACGTCGCAACACCCGCTCGAAGCATGACGATTCGATCGAGCTGGAGCTGGAACCGCTCGTTCCGGTGGTGGTGGAGTTGGGCGAAGGGCTCGGCGAGCATGCGGGCGGGGGCGTCGGCAGTGCGACCGGTGATGGTGACAATCAGCTGGCACCGGTGGCGCAGGTTTGCCGCGTCTGCCTGTGCGAAGAGAAAGACCCGGACGGGGTGACGGAGCGCAAGATGGAATCGCTCTACTGCACGGTCGTGCCGGAGTATCAGTCGCGCAGTCTCTACTCGATACTGGTGGCCGTCTGCCATCCGCTACATCTGGGCAGCAATGCCGGCATGCCGGACCGCATCTGTCTCGACTGCAAGGGCAAACTGTTGGCCTCGTACGAGCTGTACGATACGTGCCTGCGGAACGACGAACTGCTGCGCCGGAAGTACCACACGAAGCTGCTGATGGCTTCCAATGCGGCCGGCGAGGGCCGACGCATCAAGAAGGAGCGCTTCGACCATCACGGGGCCGACAACGGGGACGGAGATGATGCCGATTACGATCCGGACGGTGCGATTCGAAGCTACGGAGGTTCTGCACGTGGTCTCGGGATGAATGATCCCGACGATGCCTATCTGTATGCCCGCCAGTACCCGCTGCATATGGCCAGTATGATGAAGAAGCCGGGTGCCGGGGCCGGCATGGCAGCGTTGCGGGCCCGCTACCAGCAGCAGGCCAACGCCGGTGCTGCAAGCAAGTGGAACAAATACCAGCGGAACCCGGTTTCCTCGTCGAGTCCGATGCGCATCCAGCACGTCACGAATGGTCCGGACGCGCTACGCCACATGGGCACCGGCGATGGTAGTTTAGCGGCCAAGCGGGCAGGTTTGGCGTACGAATACAACTCGTTCCACCGGCTGCTGCCGAACGGTCAGCACCAGTGCACGAAGTGTTTGCGCGAGTTTAAGTACCACAGCTACTACAAGAACCACTACATCAGCCAGCACGATCCGACGAAGCCGTACAAGTGCCGCAAGTGTCACTACACCTTCCGCCACGAGCGCTGGCTGATCTCGCACATGCGCACGCACGTCGGATCGCTCGCAATGCTCGAGCTGGGTGCCGGCGGGGGCTCTGCGCTCGGCCAGCAGGATCTACTGGACAGCTCGGCTGGCTCTGGTGACATGATGGCGGGCGGGCAGGGTCGGGGAAGCGCTGGTGGCGGTAACGAGCTGCTGCAGTGCACACCCTGCGATCAGACCTTCCTGACGTACACACTCTACAAGCGCCACATGCTGATGCATTCGAGCAAACAGCGCTGTCCGATCTGCGAGATGCGCTTCCACGATCAGGCGAGTCTGATGGAGCACCTGCGCAACCACAAGGCCGAAAAGCAGGCGCGTACTCGGAGCGGTGGCGACAAGGAGGGAGGTGCCGGTGGCAACGAGCAGCAGCGCTCGTACGCGTGCACCGTTTGCTCGGCTTCGTTCGCCCGGGAAACCCAACTCACCGGACACATGCAGGAGCAGCATCCGAAGGCATTGCTGGCGATGTACTCGGAGCAGCTGTTCAGGTGCCGCGTCTGTTTGGTGGAATTCGACGACCGATCCACGCTCGAGACGCACTTTGCCACGCACGGTGAGGCGCAACGCACGGAGGCGATGGCGGCGGGAGCCGCAGAACGTTCCAAGGAGGAGGAGAAGAAACCGAACGACGATGACGAAGGGACCGCCGATGAGCTGAAGTCGGATATCAAAAAGGAAGAGGAAAGTAGCTCCGACGAGCAGAAGGTGGCGGGTGGCGAGGATGGTGAATCAAAGGTGAAGCACGAAACGGGTGGATCGTCGGGTGGGGATGTGGTGCCGGATGGGTTTGCGGCGGTGCACAAGTGTAAACTGTGCAAGGCGCGGTTCCCAACGAGAAGCTCCCTGGAGGCGCACATAGAGACGCACGTGGCGACGATGAAGCGCACGACGGGCAAGCGTTCGTACAACGAGAGTGGCGATGGCGATGGGTCGCTGCCGGGTCAGGAGGACGACAGTGAGGACGATGAGGAGGATGACGATGAGACGTCGGCATCGTCGAGTCGGCGAGCGAAGCGCCCGAAGCATGACGACGGTAATGGTGACGAGGAGGACGGTGCCGGTGGGGGCGGAGGTGGTGACGACGACGACGAGGAGGACCTGATCGATCCGGACGAGGTGTCCTTCCATCCGGACACGGGCGAGCAGATGTTTACGTGCCGCGTGTGTGGTAAGGTCATCAGCACGGTGACGCAGTTCCGCCGGCACAAGCGTGTCCATTCGGCCAAGGGTCGGCCGTACGAGTGTCACATCTGCTTCTACCGGTTCGCGATGAAGTACAGCTACACGGCGCACATGCTGCGGCACGAGCTCGGCTGCGATCCGACCCAACCGACCACCTACCGCTGCTCGAAGTGCTCGGAAACGTTCACCAGGCGCAAGCTGCTCAATCAGCACATCGCGACCAAGCACGGCCGCTGGTCACTGGGCGCGTCCTCCATTGCGGAGCTGCTCGGCAACCATGCACCGTCGGCTGGAGATACCTCGCTCGATTCACCGGCCAGCGCTAGCGCCAGTGGCGGCCGGGGCAGCCACACGTGTCCGGTCTGCTCGGAAACGTTTACGCGCGAAAGCGTCCTAAATGGGCACATGAAGACGCACAACCTGGAGGCGGCCCAGATGCTGCACTCGGAAGTGTGCTACCTGTGTCGGGTGTGCAGCAGCGAGTTTGAGTCGCGCGCTCTCTACGAGGCGCACGCCGCCGAGGTGCATCCGGGCACGAAAACCGACATGATGGTGGAGTCGGGCGACGGCGAGCAGGAGGAGTCGGAGTCGGGAGGCGCCAACCAAACCACCGGCACGGAAGGAGCACGGCAGCCGAAGCAGGAGGAGGAGGAGGAGGAAGGCGCATCAAACGCGGACGGAGAAGTGCGCAACGATCCGGCGAACGATGACGACGAGTCGATGCCGGGAGCCGGTGGTGGCAGCAACAGTGGCTTCACGCTCATCTACAAGTGCAAACTCTGTTCCGGGCGGTTCCTGAAGAAAAAGTCGCTCGACTGGCACCTGCAGACACATCGGTCGATCGCGAAGCAGGGCGACGGTGTGGCCATCCTGCCCGACATTGGCCCCGACGTGGATACCGAGCAGATTAAGCTGTTCAAGTGCACCGTTTGCGGTCAGATGTTCGACAATCAGATTATCTTCCAGGAGCACGTGCGCACACATCAGCTCGGCCGCGCACCGCGTCTCTCAACCGGGTACGGTTCCGGTGTCGCCGCTTCCACTCCCACCCCAACCCGCCGCAAACGTTCGTCCTGGCCGGGGCCCATCATCCAGTGTCATCTGTGCAAGAAGACGTTCACCTACCGCAGCCAGCTGCATCAGCACACGGTGCTCCATCATCAACCGGGCAAGCCGTACGAGTGCAAGATCTGCCACTACAGCTTCGTGCACGAGCTGAACCTGAAGCGCCACGAGCTGCTCCACTTGAAGGAAGCGGTAGCGGCGCATCCTACCGATTCGGCCGACGATAATTCGCACCTGCTACAGCCGATGGTGCTAATGGGCGGTCCGGATGACGAAGCGAACGGTGGGGCGAAGGATGGCAACGATGCAGCCGACGGCGGGCAACCGTCGTCCTCCGGCCAGGCGGAAGATGGTGGCGAGTGGTCGCAGCGTAAAATCAAGTGCGTTATCTGCGCGGCCCGGTTTAGCCGGCAGAGCGAGCTGGTGGTGCACCTGCAGACCCACATCGAGCGTATCAACGAGGCGCGGAATCGGCGCGCCCCGTCCCTGGCGCAGGCGACCGACATCGGCATCTCACCGAACGACCGGCAGTGCAAGCTGTGCCACAAGGTGTTCAAGTTCAGCTGCCAGCTGAAGCAGCATCACGTGCTGCACCACGCCCGCGAGAAGCCGTTCGAATGCCGCACGTGCCATTATCGGTTCGAGTTCAAGGGCCACCTGGTGCGGCACCGGGCGAACCTGCACCCGAACGAACCGAAGGACGCGTACGGCGACGGGGGTGACGGCGCCGGTACGAGCTCCAATCGCGCCGGCGCTGGAAATCTGCGCCGTTCCGGTTCGCTGCTGCTGGACGACGGCGGGGCGGCGGGCGGCGGTGTGCCAAAGTACGGCGGAATGGTCACGGACGATGTGATCATCGCACCGACCACCTCGGTGTCGCGCTCGGAGGCGGGCGGATCCGGTGGCGTTCCGACGCACCAGTGTCCGATGTGCTCGCTGAAGTTCATCAAGGCGCGCTCGCTGGCGATGCACATGCGGATACATCTCGGTGGGCGCAAGCTGCGCCGCGTTATCCCGGCTACGGCCGACGGTTCGGACGCCGGAGGGCCAGAAGGTATGTCTCCACTCCAAGGGGGTGGTATGATGGGTGGAGGCGTCGTCGGAATGCCTGGCTCGTCGGGTTCACCGTCGGGCGAGAAGCAGCGGGAGGCGCTGGTGTGTCGCATTTGCGCCGGCACGTTCTCTACGGCGCACGAGCTGAAGACGCACATGATGACGCACATCGGAGGGGAAGCGATGGACCTAGAGGTACCGTTCGGCATCAGTGCGTTCAACATNNNNNNNNNNNNNNNNNNNNTCGTCCGCCGGCGGTGGCACCGAGGACCATAG
Protein Sequence: MVPPASTVNQYSGRTSEPLPGAGQGGAYFHTDQLGAGAMGHFGVGVETGAGGGYSPGVVTGGMVRPVGLGASPNATSPPVGVPGMTGAGGAGAGGGYGHATSTPTHVTSYMQQTGGSPGALQRMSAELNASPMQQMQVPDQHRLVAPMVHTEFPTGSSRASFPPAVTLPSASPCALAGDSMVSMPKPSDMTLANNDHQLKQAQMSVITQQQSSVAATTAAGSMYGMHGVGGPMEAPLESEFTFPSVDTTNPNDAVQQQTHQSQQQSGMSLSMVGNNGTTATNNTGGMVAPTGRGDSTSDRVTRSSARNVCADVADPNEDADALVEVIPMDPLATTSDDKAADSVKGLLSKGRDDPSERKQRPVKHVRFVDDDNSLDEMPRARGNVSPHPLGMSQGGRGGMRGGNGPQEADEEDDDMDGLALMEHIPPVQSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTGATRGRGGGRRNTRSKHDDSIELELEPLVPVVVELGEGLGEHAGGGVGSATGDGDNQLAPVAQVCRVCLCEEKDPDGVTERKMESLYCTVVPEYQSRSLYSILVAVCHPLHLGSNAGMPDRICLDCKGKLLASYELYDTCLRNDELLRRKYHTKLLMASNAAGEGRRIKKERFDHHGADNGDGDDADYDPDGAIRSYGGSARGLGMNDPDDAYLYARQYPLHMASMMKKPGAGAGMAALRARYQQQANAGAASKWNKYQRNPVSSSSPMRIQHVTNGPDALRHMGTGDGSLAAKRAGLAYEYNSFHRLLPNGQHQCTKCLREFKYHSYYKNHYISQHDPTKPYKCRKCHYTFRHERWLISHMRTHVGSLAMLELGAGGGSALGQQDLLDSSAGSGDMMAGGQGRGSAGGGNELLQCTPCDQTFLTYTLYKRHMLMHSSKQRCPICEMRFHDQASLMEHLRNHKAEKQARTRSGGDKEGGAGGNEQQRSYACTVCSASFARETQLTGHMQEQHPKALLAMYSEQLFRCRVCLVEFDDRSTLETHFATHGEAQRTEAMAAGAAERSKEEEKKPNDDDEGTADELKSDIKKEEESSSDEQKVAGGEDGESKVKHETGGSSGGDVVPDGFAAVHKCKLCKARFPTRSSLEAHIETHVATMKRTTGKRSYNESGDGDGSLPGQEDDSEDDEEDDDETSASSSRRAKRPKHDDGNGDEEDGAGGGGGGDDDDEEDLIDPDEVSFHPDTGEQMFTCRVCGKVISTVTQFRRHKRVHSAKGRPYECHICFYRFAMKYSYTAHMLRHELGCDPTQPTTYRCSKCSETFTRRKLLNQHIATKHGRWSLGASSIAELLGNHAPSAGDTSLDSPASASASGGRGSHTCPVCSETFTRESVLNGHMKTHNLEAAQMLHSEVCYLCRVCSSEFESRALYEAHAAEVHPGTKTDMMVESGDGEQEESESGGANQTTGTEGARQPKQEEEEEEGASNADGEVRNDPANDDDESMPGAGGGSNSGFTLIYKCKLCSGRFLKKKSLDWHLQTHRSIAKQGDGVAILPDIGPDVDTEQIKLFKCTVCGQMFDNQIIFQEHVRTHQLGRAPRLSTGYGSGVAASTPTPTRRKRSSWPGPIIQCHLCKKTFTYRSQLHQHTVLHHQPGKPYECKICHYSFVHELNLKRHELLHLKEAVAAHPTDSADDNSHLLQPMVLMGGPDDEANGGAKDGNDAADGGQPSSSGQAEDGGEWSQRKIKCVICAARFSRQSELVVHLQTHIERINEARNRRAPSLAQATDIGISPNDRQCKLCHKVFKFSCQLKQHHVLHHAREKPFECRTCHYRFEFKGHLVRHRANLHPNEPKDAYGDGGDGAGTSSNRAGAGNLRRSGSLLLDDGGAAGGGVPKYGGMVTDDVIIAPTTSVSRSEAGGSGGVPTHQCPMCSLKFIKARSLAMHMRIHLGGRKLRRVIPATADGSDAGGPEGMSPLQGGGMMGGGVVGMPGSSGSPSGEKQREALVCRICAGTFSTAHELKTHMMTHIGGEAMDLEVPFGISAFNXXXXXXXXVRRRWHRGP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -