Basic Information

Insect: Anopheles sinensis
Gene Symbol: -
Assembly: GCA_000441895.2
Location: KE525293.1:301677-308616[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 2.1e-06 0.00015 21.8 1.5 1 23 98 120 98 120 0.99

2 14 0.012 0.88 10.0 0.5 1 23 128 151 128 151 0.98

3 14 0.00018 0.013 15.8 1.2 1 23 171 194 171 194 0.93

4 14 7.1e-06 0.0005 20.2 0.1 1 23 286 308 286 308 0.99

5 14 2.3e-05 0.0016 18.6 0.7 1 23 314 336 314 336 0.99

6 14 0.0081 0.57 10.5 2.5 1 23 434 456 434 456 0.98

7 14 1.3e-06 9.1e-05 22.5 0.8 1 23 462 484 462 484 0.99

8 14 3e-06 0.00021 21.3 0.1 1 23 588 610 588 610 0.95

9 14 0.0008 0.057 13.7 2.7 1 22 616 637 616 640 0.90

10 14 4e-07 2.9e-05 24.1 0.8 1 23 703 725 703 725 0.99

11 14 1.1e-06 7.7e-05 22.7 1.7 1 23 731 753 731 753 0.98

12 14 0.00031 0.022 15.0 0.7 1 23 1013 1035 1013 1035 0.98

13 14 1.1e-06 7.8e-05 22.7 2.6 1 23 1041 1063 1041 1063 0.99

14 14 0.042 3 8.3 1.2 2 23 1070 1092 1069 1092 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	2.1e-06	0.00015	21.8	1.5	1	23	98	120	98	120	0.99
2	14	0.012	0.88	10.0	0.5	1	23	128	151	128	151	0.98
3	14	0.00018	0.013	15.8	1.2	1	23	171	194	171	194	0.93
4	14	7.1e-06	0.0005	20.2	0.1	1	23	286	308	286	308	0.99
5	14	2.3e-05	0.0016	18.6	0.7	1	23	314	336	314	336	0.99
6	14	0.0081	0.57	10.5	2.5	1	23	434	456	434	456	0.98
7	14	1.3e-06	9.1e-05	22.5	0.8	1	23	462	484	462	484	0.99
8	14	3e-06	0.00021	21.3	0.1	1	23	588	610	588	610	0.95
9	14	0.0008	0.057	13.7	2.7	1	22	616	637	616	640	0.90
10	14	4e-07	2.9e-05	24.1	0.8	1	23	703	725	703	725	0.99
11	14	1.1e-06	7.7e-05	22.7	1.7	1	23	731	753	731	753	0.98
12	14	0.00031	0.022	15.0	0.7	1	23	1013	1035	1013	1035	0.98
13	14	1.1e-06	7.8e-05	22.7	2.6	1	23	1041	1063	1041	1063	0.99
14	14	0.042	3	8.3	1.2	2	23	1070	1092	1069	1092	0.94

Sequence Information

Coding Sequence: ATGGAGTTGAAGGTGGAGAAAAAAGACGATTCAACATCTGCTGCGCCTGCCTCGACGATGGTGGTCGATGATGACGACGCCAACTCCGACCAGGAGATAGTGGAGGTTGGCATCGACGAGGATCACATTAAGTTTCTCACCAGTATGCACTCGGGCGACGAGGAGCTGGCCAACGGGCACCAGCGTGGCACCTTGGGCCATCGATCGCATCAGCAGCAGAAGCAGCAACAGCACCGCGGCGCAGGCGGTGGAGTAGGCGGCGCTGGTGTTGCTGGTACAACCGTACGAACGTATCAGTGCGACGCGTGCCCAAGGACGTTTCAGCGACCGGATCATCTGCGCTACCACATGCGCATCCACGAGAAAAGCAGCAGCAATCCGTTCGAGTGCAAGCTGTGCTTCAGCGTGTTTGCGTCGGATCCCGCCTTTGCGCACCACATTCGCACCGAGCACGCCGGTATGGGACTGGCCGATGCGCTGCCCCCGGTGCCCGAGACCGAGGCCCAACAGCACGCCTGCACCTACTGCGATCGGACGTTCGGGGACGCGGACGAGCTGGAGGATCATCTGCACCAGCAGCATCTGGGCGTGCGGCCGTTCAAGTGCAACATCATTTCGAGTGACGACGATGAAGATGGCGATGAGGATGAGGACGGGGATGATGAGGGAACGGGTGCTGAAAGTGCTACCGATCATCATCATCAGCACCACCATCATAAGCTGGTGCTCCGTAAAGGGATGGCCAGTGCCAGTGGTGGGCGTAGTGTGCTATCGAAAGCTGGAGCCGCCGTTGGACCGAACAAAAAGAAAGTCGCACCCGCTGTGGTGGAACCGCCGGTGGAGGAGGTTGGCCAGTTCCGCTGTCCGGTGTGCGAGCGACGATTCATCCGCGAGCCAGATCTTATGATTCACGTGCGAACACATCCAGATCTTCCTACCTTCAAGTGTCCCCTTTGCGAGCTGACCTTTATCGGATCGGACTATTTGAAAAATCATCTCAAGAAACACGTGCTCGGCAATGGCGAAGATCCGGGTGCACCAGGAGCAATCGATTTGAAGTCCCTTCCCGACCCCGCAACGATAGCAGCTCCTCCGGACGCCCCTCCGTCCACTACGAACGGTGCTGGCGGAGGTGACGCTGAGCCAGGGGAACCAATTGAGCCAACGGTCGCGGCGAAACTACCGAAACCGATCATTACGTCCAAACCACCGTCGTCCGGGATCTCCCTGTTGAAACCGATCGAAGAGCGGAAACCTCCGGAACCGCAGGAGTACTGCGTGAAGACGGCCGACGGCAAGTTTATGTGTACGGTGTGCGAGCGGCTGTTCTCGCACCAGCAAACGGTGCGAATTCACTTCCGCATCCACACGAACGAAAAGCCGTACAAGTGTGCGTACTGCACCGAGTCGTACATTCGCTCGGATTATCTCGAGCGCCACATGAAGGTGCACTTCAAGGATGGCATACTACCGGCGGCCGCCATTGCCAGCATGGCGGCAGTAGCGGCGGCGGCGGCAGCGGCTGCTGCAGCAGCATCCTCCGGTGCCAGCACAACTCGAACGGCGGATGTAGCGTCACCACCTCCACCAGCACCACCACCACCTTCCGCTTCTGTGGTGAAGGAAGACATTCCCGAAACGACGCCGGTGGTGGCCGCCACTCCTTCACCCGTGAGCACCACCACCACCACGAAGCCATTGATCGGTCGGGCCGGGCTAGCGCCGGAAAACTATCACTTTACCGAGTCGAACGATGGGCAGTTTGTGTGCAAGATCTGCGATAAAGTGTTCAGCCAGGTGGCTCAGCTGCGCAAGCATGCCTTAGCGCACACGGAAGAGAAGCCGTTCTACTGCGAAACCTGTGATCGATCGTTCAACCGGGTGGACTATCTGAAGGAGCACTTTAAATCGAAGCGGCACCTTCAACTGCTGGCGGAAGCTGCTGCTGCTGCTGGTGGAGCGGATCCGTCGAACCGTATGGAGGAGCAGGAGGAGGAGGATGATTCCACGATGGACAGCGTATCGGTGCCACCAACGGCCGACGACGCTCGGTCCGTGCTGGGCGAGTTCCATCGGTCGGACTACGAGCGCACCAGCGACGGCCGGTACAAATGTAACCAGTGTGATAAAACGTTCGTGACGGCGGTCACGCTCAAGATGCACATCCGGCTGCACACGGGCGAGAAGCCGTACAAGTGCGACAAGTGTGATAAGGCGTTCATTCGCTCGGACTATCTGAAAACGCACGAAAAGTCCCACCGGCAGGAGTCGTTCCTGAGCATGCTGTCCCTGACGACGTCGAAGGAGCCCAGCACGGCCTCGGAAGCCGGTGACTCCGATACCGGAGGTGTTGGGGGCGGCGTTGGCCCGCACGAGCGTGATGATACGCGTTCCTCGATCGGTGATGCTGGTGGGACGATGGGACGTAAGCCGTTCTCCGGTGCTAAGGATGTTGAAAGCGATGAAGAGGAGGATGGGGAGGAGGAAGAGGAGGACGAAAATGAAGGATCGGGTGAGGATGACGAAGATGAGGACGAGGAGGAGAGCGAAGAGGAGGAACAGGTGATTGAGGTTATGGTGAAGGAAGCGAGCTGCTCCGAAAGTGACAACGACGACGAAGAGGAGGACGATGAAGCGGTGGAACGTGATGCCAATGGTAACGAAGGTGATAATGCGTGCGAGGAGGAAGCAGAAGACGAAGAGGATGAAGATGACGACGAGGGCGAGGAGGAAGAGGATGATGACGATGAAGAGCTGAAGAAAGGCAGCGCAATACAGCAACGCTTTGGTGGAAACAACAGCAAAAGTACAAATCACTTTATGGAGCAAAAAATGCACCGTCGAAAGGAACCCAAAAGTTCCTCGTCGAAGCGAAGTAAACAGCGGCCACCGCAACACCGTGCAACGGAGGTAAGCGGAGGCGACAGTAGTAACAACGGGTACGATCACGACGACGAAAGCATGTCGCAGACGAGTGGGGCCGGTGGCGGGGGAGCGGGCAGCAACTCGGAACAGGCGCAAAACCAGAAGGGCAAACATCGCTGCCCGATGTGCGACAAGCTGTTTGCGTGGCCCAAGTCGTTGAAGATCCACGTACGCACACATACCGGCGAGAAGCCGTACCGCTGCGACGTTTGTGGCAAATGTTTCGGCCGATCGGACAGCTTGCGCGGCCACAAGCGAACCCATGCGCTCGAGGGCCAGTTGCAGTGTCATCTGTGCGAAGTCAGCTGCAACAATACGGCCGGATTGATACAGCACCAGAGCTTGGTGCACGGAATACAGCCGCTGGAGAGCTAA
Protein Sequence: MELKVEKKDDSTSAAPASTMVVDDDDANSDQEIVEVGIDEDHIKFLTSMHSGDEELANGHQRGTLGHRSHQQQKQQQHRGAGGGVGGAGVAGTTVRTYQCDACPRTFQRPDHLRYHMRIHEKSSSNPFECKLCFSVFASDPAFAHHIRTEHAGMGLADALPPVPETEAQQHACTYCDRTFGDADELEDHLHQQHLGVRPFKCNIISSDDDEDGDEDEDGDDEGTGAESATDHHHQHHHHKLVLRKGMASASGGRSVLSKAGAAVGPNKKKVAPAVVEPPVEEVGQFRCPVCERRFIREPDLMIHVRTHPDLPTFKCPLCELTFIGSDYLKNHLKKHVLGNGEDPGAPGAIDLKSLPDPATIAAPPDAPPSTTNGAGGGDAEPGEPIEPTVAAKLPKPIITSKPPSSGISLLKPIEERKPPEPQEYCVKTADGKFMCTVCERLFSHQQTVRIHFRIHTNEKPYKCAYCTESYIRSDYLERHMKVHFKDGILPAAAIASMAAVAAAAAAAAAAASSGASTTRTADVASPPPPAPPPPSASVVKEDIPETTPVVAATPSPVSTTTTTKPLIGRAGLAPENYHFTESNDGQFVCKICDKVFSQVAQLRKHALAHTEEKPFYCETCDRSFNRVDYLKEHFKSKRHLQLLAEAAAAAGGADPSNRMEEQEEEDDSTMDSVSVPPTADDARSVLGEFHRSDYERTSDGRYKCNQCDKTFVTAVTLKMHIRLHTGEKPYKCDKCDKAFIRSDYLKTHEKSHRQESFLSMLSLTTSKEPSTASEAGDSDTGGVGGGVGPHERDDTRSSIGDAGGTMGRKPFSGAKDVESDEEEDGEEEEEDENEGSGEDDEDEDEEESEEEEQVIEVMVKEASCSESDNDDEEEDDEAVERDANGNEGDNACEEEAEDEEDEDDDEGEEEEDDDDEELKKGSAIQQRFGGNNSKSTNHFMEQKMHRRKEPKSSSSKRSKQRPPQHRATEVSGGDSSNNGYDHDDESMSQTSGAGGGGAGSNSEQAQNQKGKHRCPMCDKLFAWPKSLKIHVRTHTGEKPYRCDVCGKCFGRSDSLRGHKRTHALEGQLQCHLCEVSCNNTAGLIQHQSLVHGIQPLES

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -