Basic Information

Insect: Anopheles sinensis
Gene Symbol: -
Assembly: GCA_000441895.2
Location: KE525352.1:3039243-3044147[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.00017 0.012 15.8 0.3 1 23 117 139 117 139 0.99

2 17 3.3e-05 0.0023 18.1 3.9 1 23 220 242 220 242 0.97

3 17 0.00029 0.021 15.1 0.9 2 23 317 338 316 338 0.97

4 17 3.5e-05 0.0025 18.0 4.4 1 23 418 440 418 440 0.97

5 17 5.9e-06 0.00042 20.4 1.5 3 23 504 524 503 524 0.98

6 17 0.13 9.3 6.7 0.7 1 16 591 603 591 610 0.73

7 17 3.9e-06 0.00028 21.0 2.0 1 23 673 695 673 695 0.97

8 17 3e-07 2.1e-05 24.5 0.6 1 23 701 723 701 723 0.99

9 17 1.1e-08 7.8e-07 29.0 1.0 1 23 729 751 729 751 0.98

10 17 7.5e-09 5.3e-07 29.5 1.8 1 23 757 779 757 779 0.98

11 17 0.00028 0.02 15.1 0.3 2 23 782 803 781 803 0.95

12 17 0.00029 0.021 15.1 0.4 1 23 809 832 809 832 0.97

13 17 2.4e-08 1.7e-06 27.9 4.7 1 23 838 860 838 860 0.99

14 17 0.0003 0.021 15.1 1.5 1 23 866 888 866 888 0.98

15 17 3.4e-08 2.4e-06 27.5 1.8 1 23 894 916 894 916 0.99

16 17 1.2e-06 8.2e-05 22.6 3.6 1 23 922 944 922 944 0.99

17 17 3.1e-08 2.2e-06 27.6 2.0 1 23 950 972 950 972 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.00017	0.012	15.8	0.3	1	23	117	139	117	139	0.99
2	17	3.3e-05	0.0023	18.1	3.9	1	23	220	242	220	242	0.97
3	17	0.00029	0.021	15.1	0.9	2	23	317	338	316	338	0.97
4	17	3.5e-05	0.0025	18.0	4.4	1	23	418	440	418	440	0.97
5	17	5.9e-06	0.00042	20.4	1.5	3	23	504	524	503	524	0.98
6	17	0.13	9.3	6.7	0.7	1	16	591	603	591	610	0.73
7	17	3.9e-06	0.00028	21.0	2.0	1	23	673	695	673	695	0.97
8	17	3e-07	2.1e-05	24.5	0.6	1	23	701	723	701	723	0.99
9	17	1.1e-08	7.8e-07	29.0	1.0	1	23	729	751	729	751	0.98
10	17	7.5e-09	5.3e-07	29.5	1.8	1	23	757	779	757	779	0.98
11	17	0.00028	0.02	15.1	0.3	2	23	782	803	781	803	0.95
12	17	0.00029	0.021	15.1	0.4	1	23	809	832	809	832	0.97
13	17	2.4e-08	1.7e-06	27.9	4.7	1	23	838	860	838	860	0.99
14	17	0.0003	0.021	15.1	1.5	1	23	866	888	866	888	0.98
15	17	3.4e-08	2.4e-06	27.5	1.8	1	23	894	916	894	916	0.99
16	17	1.2e-06	8.2e-05	22.6	3.6	1	23	922	944	922	944	0.99
17	17	3.1e-08	2.2e-06	27.6	2.0	1	23	950	972	950	972	0.98

Sequence Information

Coding Sequence: ATGCTCGGTAAATATGCTGACGCGAGTTCCAGCTCGATGATAAACCTGGAAAATGGTCTCCGAAACCGTGTGCTGTACCATCAGAACATGATGGGCATGAATCTGATGGCCGAGTTTTACCACAACCCTCTAATGAACTCCTCCGGAAGCAACGGTGCCGGTGGCAGCGACGCTGTTGGTGCCGGCTCAATGTTATCACCGTCGCAAAAGATGCTCAACATTCTGTCAGTTAGCGCTGGAAGCAATCTGCAACCGCATCACACCGGAAATAGTTCCGTGGTGTCAACACTACCGGTTGGTTCTTCATCGACGGCATCGAGCGGTTCATCGCAGCAATCGTTGGTGCAGTTTCAATGCCAACTTTGCCAAAAGTACTTTATTTCCGGAGCGGCACTCGCACAGCATATTAAAACACACGAACATGATTACCTTGCGCGGGAAGAATCCGGTCCAGTCAGCGGCGGTTATAGTCAGCAGCAGTCGATAACGTCCGCTCCGTCGCTTGTAACGACGGTGGCTTCGAGTAGTAAAACTAGTTCACCATTGCTTGCACAGCAAAGCATCAAGAGTGAGTATATTGTACGAAGTACGTCGTCTGCGTCCGTGCCCTTGCCTGGTGGGAACCAATTTCCTCCCGCGTACGGTATTACGAAACAGTTTGACTGTCACATCTGCCACAAATCGTTCATGACGATAATGAACCTTAACCTGCATATGAAAATCCACGAAGAGTTAAAGCCGGCAGTGGTTTCTTCACTTGCGAATCCGTCCGGTGGTAGCAGCGGAACCGTAACGTCACAGGCGCAAAAGACACTCAACATTATGTCGCACCATGCTAGTGCGGGAAGTACTCCACAACTGCAGCACCCCGGAAATGGTTCAGCTGTGACGACAATAGCACTAGGCACCGTGTCGACGACATCGAGTGGTACATCGCAGCAACCGTTGCAATGTCAAATTTGTCAAAAGTACTTCATTTCCGGCACTGCACTGGCGCACCATATTAAAACACACGATAATGACTACCTTGCGCGGGAAGAATCCGGTCCCGGTGGCAGCTATAGTCAGCAGCAAACGGTAACGACGGCACCATCGGTAGCAACGGCAGTGGCATCGAGTAGTAAAACTAGTCCCCCACTGCTACCACAGCAGAGTATAAAAAGTGAGTACATTGTACGAAGTACGTCGTCTTCGTCCGTGCCCTTGCCTGGTGGGAACCAATTTCCTCCCGCGTACGGTATTACGAAACAGTTTGACTGTCACATCTGCCACAAATCGTTCATGACGATGATGAACCTTAACCTGCATATGAAAATTCACGAAGAGTTGAAACAAACAGCTGCAACCCACGTCTACCCACATGCCACGGCTCATGGTGCTACAAGTGCAGGGACATCGTCTAACGATTATCATCACCACCATCAGCAGCACCAGAACAATTATCACAACAACCCGCAGCAGCACATTTCGATGATGGCGGCGACATCGACGATTGGGACGGATGGTGCGTGCCAGATTTGCCATAAAACATTCAGCACGGTCGAGCAATTTACGGCACACATGAAGATACACGAAAACGAGTTTAGGAATCGTGCCCTCTACCACTCCGGCAGCTCCAATACCATCAGTGCCGGTGTCGAAGGAAGCGTAGTTGTCCAGAATCCGCCAACGGCGGCAGATTCTTTCTATCCTTCGACTCAATCACAGCCGATTCTCGCACAACAACAGCAACAACAAACGGCTGGACCGCAATTTGACGCCATGAAAGGATATCGATGTCCCATCTGTCACAAAATGTCTAGCAACATCATCGAACACATCAAACAACACGAAGGGCAGCTAATGTTAGGTGAAGGTGCTGCGAGTAGCGGAAGTGGAACGACACCACCCACGCCGGATGTGACTTCGCCTACGCCGGAAGCGTTAACGTATCATCCGATGAACGAAGATACGCAATCATCGCTCGAAGGAGACGACAGCGAAGGCCAGACGGGAGAAGGAGCCGACGTCCGAAAGCACGAGTGCCTCCTGTGCCACAAAAAGTTTTCGAGCTCGGGAAATTTAGCCATTCACATACGGGTGCATTCGGGCGAGAAACCGTTCAAATGTAGTGTCTGCGGGAAGGGTTTCATCCAGTCGAACAACTTGGGGACGCATATGAAAACGCACACGGGCGAAAAGCCGTACGCGTGCACGATTTGTGGGAAAAACTTTTCGCAATCCAACAACTTGAAAACGCACATCCGGACGCACACCGGCGAAAAGCCTTACGCGTGCACCATCTGCGGGAAGCGGTTCAATCAGAAGAACAATTTGACCACGCACATGCGCACGCACCAGCTGGTGTGCATGGTGTGCGGCGTGCAGTTCATGCATCCGTCCGACCTGGCCAACCACATGAAGTTTCACAACGACGAAAAGCCGTACATCTGCTCGGTGTGCAACAAGGTGTACCTCAACCTGGACGAGCTGACCGAGCACATGAAGAAGACGCACAACCAGGTTAAGCCGTACCGGTGCCACATCTGCGACAAAACGTTCACCCAATCGAACAACCTGAAGACGCACATCAAGACGCACATCTTCCAGGATCCGTTCAAGTGTCAGATGTGCTCGCGCTCCTTCCAGAAGGAGGACGACTACTCGCAGCACATGCTGGTCCACACGGCCGACAAACCGTACGAGTGTACGTACTGCGGGAAGCGATTCATTCAGTCCAACAACCTGAAGACCCACGTCCGGACGCATACGGGTGAAAAGCCGTACCGTTGTACAATCTGCGCAAAGCACTTCAACCAGAAAAACAATCTCAATACGCATATGCGCATCCATACCGGCGAAAAGCCCTTCGAGTGCACCATCTGCGATAAGCGATTTAACCAGTCGAACAATTTGAATAAGCACATCAAAACGCATGGTCAAGAAAAGGACACGCAGCAACAGCATACAAGTTGA
Protein Sequence: MLGKYADASSSSMINLENGLRNRVLYHQNMMGMNLMAEFYHNPLMNSSGSNGAGGSDAVGAGSMLSPSQKMLNILSVSAGSNLQPHHTGNSSVVSTLPVGSSSTASSGSSQQSLVQFQCQLCQKYFISGAALAQHIKTHEHDYLAREESGPVSGGYSQQQSITSAPSLVTTVASSSKTSSPLLAQQSIKSEYIVRSTSSASVPLPGGNQFPPAYGITKQFDCHICHKSFMTIMNLNLHMKIHEELKPAVVSSLANPSGGSSGTVTSQAQKTLNIMSHHASAGSTPQLQHPGNGSAVTTIALGTVSTTSSGTSQQPLQCQICQKYFISGTALAHHIKTHDNDYLAREESGPGGSYSQQQTVTTAPSVATAVASSSKTSPPLLPQQSIKSEYIVRSTSSSSVPLPGGNQFPPAYGITKQFDCHICHKSFMTMMNLNLHMKIHEELKQTAATHVYPHATAHGATSAGTSSNDYHHHHQQHQNNYHNNPQQHISMMAATSTIGTDGACQICHKTFSTVEQFTAHMKIHENEFRNRALYHSGSSNTISAGVEGSVVVQNPPTAADSFYPSTQSQPILAQQQQQQTAGPQFDAMKGYRCPICHKMSSNIIEHIKQHEGQLMLGEGAASSGSGTTPPTPDVTSPTPEALTYHPMNEDTQSSLEGDDSEGQTGEGADVRKHECLLCHKKFSSSGNLAIHIRVHSGEKPFKCSVCGKGFIQSNNLGTHMKTHTGEKPYACTICGKNFSQSNNLKTHIRTHTGEKPYACTICGKRFNQKNNLTTHMRTHQLVCMVCGVQFMHPSDLANHMKFHNDEKPYICSVCNKVYLNLDELTEHMKKTHNQVKPYRCHICDKTFTQSNNLKTHIKTHIFQDPFKCQMCSRSFQKEDDYSQHMLVHTADKPYECTYCGKRFIQSNNLKTHVRTHTGEKPYRCTICAKHFNQKNNLNTHMRIHTGEKPFECTICDKRFNQSNNLNKHIKTHGQEKDTQQQHTS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00108044;
90% Identity: iTF_00108044;
80% Identity: iTF_00108044;