Basic Information

Insect: Anopheles quadriannulatus
Gene Symbol: -
Assembly: GCA_000349065.1
Location: KB666065.1:423021-425708[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 4.1 2e+02 2.2 2.0 1 23 267 291 267 291 0.96

2 8 7.3 3.6e+02 1.4 0.4 10 23 319 332 306 332 0.79

3 8 3.6 1.8e+02 2.4 2.0 3 19 340 356 338 358 0.90

4 8 8.6e-06 0.00042 20.1 0.7 1 23 368 390 368 390 0.98

5 8 6e-05 0.0029 17.4 0.1 1 23 394 417 394 417 0.95

6 8 0.00099 0.048 13.6 0.5 1 23 423 445 423 445 0.97

7 8 0.0064 0.31 11.0 0.2 1 23 450 474 450 474 0.97

8 8 9.9 4.9e+02 1.0 5.0 1 23 482 507 482 507 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	4.1	2e+02	2.2	2.0	1	23	267	291	267	291	0.96
2	8	7.3	3.6e+02	1.4	0.4	10	23	319	332	306	332	0.79
3	8	3.6	1.8e+02	2.4	2.0	3	19	340	356	338	358	0.90
4	8	8.6e-06	0.00042	20.1	0.7	1	23	368	390	368	390	0.98
5	8	6e-05	0.0029	17.4	0.1	1	23	394	417	394	417	0.95
6	8	0.00099	0.048	13.6	0.5	1	23	423	445	423	445	0.97
7	8	0.0064	0.31	11.0	0.2	1	23	450	474	450	474	0.97
8	8	9.9	4.9e+02	1.0	5.0	1	23	482	507	482	507	0.88

Sequence Information

Coding Sequence: ATGGATCGAACGTGCTGTCAAACGGGTGTGTTTACAGTCTCAACAGCCCGCGTTTTGTGCGACTCGCGAGGAGGCGATTCTAGCGTGACTTTTTTTTGTTATTTGCAGTGTTTTCCGAGCCCCCCAAAAAAAACCTCAGCAATGGATAAGCGCTCGAAAAAGCGTAAAAGTCAACCAAGCAGCGAACTGTCCACCGAATCGAAGAAGCTTAAGCTCGCGAAAGAGGAGCAGACGAAGGAGCCAGCAGCTTCCGATAATGTTTCAGAAGAGGCGGTGGCAGCAGTGCCATCAAGCGTTGATCAATTACACGACCTACAAGCAGACATCAGCAGTTGGCTCGAGAAGCAGGAAGAGTTCGACCAAATGGACCTAGAAGCGCTGGAGGAAGCGAGTAACCATGACGATGAACCGGAGGATAACATTGATTTGGAAGCGCTCGATGTTCCCGTTGGCGTAAGGTGTGCGAAATTCAGCGATAAGGAGATGCGAAAAAGCTACAAGTACGAGTGCGAGTGGGGCAAGTGCAAGTTCATGAGCGGCACGGATCGCAAATACTTCCTGCACGTCGAATCGCACGCCGAGCTAGCGCTGGAAACGGAGGCCGGAAAGTATACATGCCGGTGGGATCTCTGCGAGTACAGCACCGAGGATGGGTACGAGTTTGTCGGGCACGTGCACTACCATGCGTACCATACGAAGCTGAAGGTGCACGGTGCCAGCCTGCATTTGCTGCTGAAGCTGCCGAACTGTAACAACGACAGCCGGACGCGAAACGCGATCAGCAACCGGCCGGTCACGTTCCAGTGCGAATGGAACGAGTGCAGCGATCGGTTCAACAAGGCACTGCATTTCTTTTACCACGTGAAGGGCCACATTGACGATATGTGGCCAGCCGGAAAGTGGACAAGCCAAAAATTTAGCTGCAAGTGGGCGCTCTGCACCACGAAAAGCAAGCTGACGAGTCGGAAGGATTTGATGAAGCACCTCGTATCGCACACGACGGAGCGGCTCATTGCGTGCTTTAACTGTGGTACACACTTCCGGATTCGCGATAAGTTCGTCGACCATTGCAACCGACAGCTGGAAATAGCACATCGCAAGTATCAGTGCGACCAGTGCGGTCGGTACTATGCCACCAAGCCGCTGCTGAACAATCACATGCAGTATCACAGACAGGCGCACGCGTGCGAATTGTGTCCGGCCAAATTTTCCAGCCAGGGCTTGCTGGCGGCACACATCCGCATCAAGCACCTGAACCAGCGTGACTTCAAGTGCCCGCAGTGTGATTATGCGTCCCATTACAAGAAAGATCTGGTGGCTCACATACTTGGCCACGAAGGGAAGCTGTTCCGGTGCGAGGAGTTTGGCTGCAATGTCGTCTACCGGACGTTACTTGGTTTGAAAAAGCACATCAGTTGGCACTATAATTTACCAACACCGGTGTACGCGTGTCATCTTTGCGATAATCATCCACGCTACAAATCATCGACTTCGCTGAAGAAGCATTTTCTCTTTAAGCACGATATGGCACGGCCGCCGGGGCTGTCGCGGTTTCGCTTCAAGCCCGACACTGACGGCATGTACCGCCTGCAATCATTCGTGGACGAAAAGCTGAGGAAACACCACGAAGAGCAGCAGGCTCTGGAACAGCAACAGAATAGTGGTGAGGCTAACGAGGGCAGTGGGCCGGCTGGAAGCAAGGACAAAAGGAAACAGCAAACATCACAAGCGAAAGCGGTGCAACCAATGCAGGATGAAGCGAAACCAACCGCCCTGGCGGAGGCAATGACTGCGCCGAAACCGAAGCTTAAGATAAATTCCATGAAGTCGATTGGAATACGCAAGTTTCAGATTGAGTTGGGCGTTGAAGCGGTAGAAGCAGGATCGTCATCAACCAATGCAGTGCCAGCAACGACGGCATCACCATCGGCAGGTGGCGCAGCGATTGCAAAACAATTGCCGGGACAGCACGGAACAGCAGCAGCGGAAGCCGCTGTGCGTCCGCCGGTGGGCATAAAGCAGGAGAAGGTGGAAGATTCGAACCATTTCGGCACGGAATCGACCAAGCAGCCGAAAGATGTGAAGGATTTTATGGTAATGAAGCGGTACTTGAAATCGAGCGCAAAGCCGTCAATCAACGCCTAG
Protein Sequence: MDRTCCQTGVFTVSTARVLCDSRGGDSSVTFFCYLQCFPSPPKKTSAMDKRSKKRKSQPSSELSTESKKLKLAKEEQTKEPAASDNVSEEAVAAVPSSVDQLHDLQADISSWLEKQEEFDQMDLEALEEASNHDDEPEDNIDLEALDVPVGVRCAKFSDKEMRKSYKYECEWGKCKFMSGTDRKYFLHVESHAELALETEAGKYTCRWDLCEYSTEDGYEFVGHVHYHAYHTKLKVHGASLHLLLKLPNCNNDSRTRNAISNRPVTFQCEWNECSDRFNKALHFFYHVKGHIDDMWPAGKWTSQKFSCKWALCTTKSKLTSRKDLMKHLVSHTTERLIACFNCGTHFRIRDKFVDHCNRQLEIAHRKYQCDQCGRYYATKPLLNNHMQYHRQAHACELCPAKFSSQGLLAAHIRIKHLNQRDFKCPQCDYASHYKKDLVAHILGHEGKLFRCEEFGCNVVYRTLLGLKKHISWHYNLPTPVYACHLCDNHPRYKSSTSLKKHFLFKHDMARPPGLSRFRFKPDTDGMYRLQSFVDEKLRKHHEEQQALEQQQNSGEANEGSGPAGSKDKRKQQTSQAKAVQPMQDEAKPTALAEAMTAPKPKLKINSMKSIGIRKFQIELGVEAVEAGSSSTNAVPATTASPSAGGAAIAKQLPGQHGTAAAEAAVRPPVGIKQEKVEDSNHFGTESTKQPKDVKDFMVMKRYLKSSAKPSINA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00101326;
90% Identity: iTF_00101326;
80% Identity: -