Basic Information

Insect: Anopheles quadriannulatus
Gene Symbol: -
Assembly: GCA_000349065.1
Location: KB665544.1:147927-150799[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.21 10 6.3 0.1 2 23 332 353 331 353 0.95

2 12 0.096 4.7 7.3 0.4 1 23 359 387 359 388 0.93

3 12 0.00054 0.026 14.4 1.8 3 23 393 413 391 413 0.97

4 12 7.6e-05 0.0037 17.1 2.5 2 23 419 440 418 440 0.97

5 12 4.7e-05 0.0023 17.8 0.4 1 23 448 470 448 470 0.99

6 12 0.0012 0.057 13.4 4.6 3 23 478 498 476 498 0.97

7 12 0.36 18 5.5 1.0 2 15 505 518 504 527 0.76

8 12 0.66 32 4.7 0.2 2 23 556 580 555 580 0.96

9 12 9.8e-05 0.0048 16.8 1.3 1 23 584 606 584 606 0.97

10 12 9.9e-06 0.00048 19.9 0.9 1 23 612 634 612 634 0.99

11 12 3.1e-08 1.5e-06 27.8 1.2 1 23 640 662 640 662 0.98

12 12 8.6e-05 0.0042 16.9 3.4 1 23 668 691 668 691 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.21	10	6.3	0.1	2	23	332	353	331	353	0.95
2	12	0.096	4.7	7.3	0.4	1	23	359	387	359	388	0.93
3	12	0.00054	0.026	14.4	1.8	3	23	393	413	391	413	0.97
4	12	7.6e-05	0.0037	17.1	2.5	2	23	419	440	418	440	0.97
5	12	4.7e-05	0.0023	17.8	0.4	1	23	448	470	448	470	0.99
6	12	0.0012	0.057	13.4	4.6	3	23	478	498	476	498	0.97
7	12	0.36	18	5.5	1.0	2	15	505	518	504	527	0.76
8	12	0.66	32	4.7	0.2	2	23	556	580	555	580	0.96
9	12	9.8e-05	0.0048	16.8	1.3	1	23	584	606	584	606	0.97
10	12	9.9e-06	0.00048	19.9	0.9	1	23	612	634	612	634	0.99
11	12	3.1e-08	1.5e-06	27.8	1.2	1	23	640	662	640	662	0.98
12	12	8.6e-05	0.0042	16.9	3.4	1	23	668	691	668	691	0.96

Sequence Information

Coding Sequence: ATGAGCAAAACCGCTGCGACAAAACCGGGCGTAACGTCGCCCGCGGAAGTCACGTCCGACGCGTTTTGTCGAATATGTTTGCTGAAGCGGCCCCACCTGAAGTCGCTGATGGAGCGGGTCGATGGCGTGATGATACCGGAAATGCTGTACAAAGTGTGCGGCCGCCAGATCGAGGTGCAGGAGGGCTACCCGCGCAGCATCTGCCAACGGTGTCTGTGCCAGTTGGACTGTGCGTTTAAATTTTTGAACGAGTTCCACCAGCAGGACGAACGTTTGCGCAGCTTCTACTGGAGCGGTTCCGTGGTGAAACGGCTGCAGGAATACCAGAAGGAAGGGAGTGAAACGGTGGAAAAACGGTTTGCCGAACTGGTCACCCGTAATGCGAAAATGCTGAGCCCGCCCACTAAGCACATGTGCCACCGGGAGACGAACACCAGCCTGCGCCCCAAACTGGTCGATGCTAGTACGCTGACAGACAAGGAGGAGGTGGCGGATCTAGCGCTGGTCAAAACGGAGGACGGAAGCGTAGTGTCCGACGATTTGGTGGTGGAGGACGAGGAAGGAGTGTATCTCGAGTATGCGGACGATTTCGATGCATCCATCAAGGACGAGCAGCTGGTGTCGATGAAAATCGATGTGCTGCAATCGGGCGACGAGGCGGAATCGTACGCCGAACCCAAGGAGCGCAGGAAGCGAGCGCCACAAACGGCCACCAAAAGCACCCCGTCGTCACGTTGGTCGACTCGGACAAGCCAACCTTTGCCGACGAAGCAGCAGGAAGACAGCGATACGGATGATCCGGCTACGGAGGAAGATTTCAAGGAGCTGTTCGAGGAAAGCGAACCAGACACTGTGTTAGAGATGGACGAGGATGAGGAAGACGATGATTTTGATGAAGAGGATGAGGATGAGGATGAAGAGGAAGATGACGAGGCTGAGGAGGCGAAGCACATGCTGGAGGAGCAGACGCCGCCGGTGCAGCTCGATCCGCTGCGCTGCTACATCTGCGACCGAAACGAGGAATCGAAAGCGATGCTGGAGCAACATCTCGATATGCACAGCCTGATGCTGCCGTACGAATGTAGAATTTGCCAGGTGGAGGGTGGACCCGCCCGCACGCTCAAAACCATCTCCTCCCTGCAGAACCACTTCCGCTCGCACCACTACCCGTTCGGGTGCGGCACTTGCGGCAAGCGGTTCCTGCGCAAAGCGCACCTGATGACGCACATGGACAGCCACAACGAGGAGCACCTGGAGTGTGGCGAGTGCGGGCGACAGTTTACGCACCGCAAAACGTGGCAGAACCACCTGAAGCGCCACGAGGCCGTGCGGACTGGCGCGTTCAAGTGCGGCACCTGCGGCCGGGCGTTCGGCAACCGGGCCCGGTTGGATCGGCACGTGCGCTCGCACACCGGCGAGCGGCCGTTCGGGTGCAAGTACTGCGACAAGCGGTTCTACGATCGCCACCAGCAGCAGCGCCACACCGAGCGGCACTTCCGCGACCAGGAGTGCAGCTGCGAGATTTGTGGCGAAACGTTCCCGGGCGCCAAGAAGCGCGACCAGCACAAGGTCGAGCAGCATCTGCGCGGCCCGGAGCTGGAGGCGTTTTTGGCGCGCAAATCCAGACAGCGGTCGTACAAGAAGCCGGCCGTACTGAAGGATAAGAAGTGCCCGTTCGCGGGGTGCGATTACATCGCCAACACGTACGGCGCGATGTACGTGCACAAGCGCACCAAGCATCAGCCGGTGCACAAGTGCGAGCTGTGCAACAAATCGTACGCCTTCCTCAACCAGCTGCGGGTGCACATGGCGCTGCACACGGGCGAGAAACCGTACCAGTGTGAGATTTGCGGGCGCAACTTCCGCCGCGGGTTCAGCTACAAGGAGCACATGGAGATGCACAACCCGGAGGCGACCTACAACTGTCCGACGTGCAACAAAAGTTTCAAGCGGCCCCGGTACCTGCAGGCGCACATGCTGACCCACACCGCGGTGCGCAAGTTTTCGTGCGAAATCTGTGGCAGCTGCTACAAGACGAACGGGGAGCTGAAGAAGCACACCAAGAACAAGCACGGGCTGGACATTGTGGAGGAGGAGGTGCGCGAGATAGTCATCGATGCGGATGATACGGATATATCGTCGTTCGTTGTGGAGTACGTTTGA
Protein Sequence: MSKTAATKPGVTSPAEVTSDAFCRICLLKRPHLKSLMERVDGVMIPEMLYKVCGRQIEVQEGYPRSICQRCLCQLDCAFKFLNEFHQQDERLRSFYWSGSVVKRLQEYQKEGSETVEKRFAELVTRNAKMLSPPTKHMCHRETNTSLRPKLVDASTLTDKEEVADLALVKTEDGSVVSDDLVVEDEEGVYLEYADDFDASIKDEQLVSMKIDVLQSGDEAESYAEPKERRKRAPQTATKSTPSSRWSTRTSQPLPTKQQEDSDTDDPATEEDFKELFEESEPDTVLEMDEDEEDDDFDEEDEDEDEEEDDEAEEAKHMLEEQTPPVQLDPLRCYICDRNEESKAMLEQHLDMHSLMLPYECRICQVEGGPARTLKTISSLQNHFRSHHYPFGCGTCGKRFLRKAHLMTHMDSHNEEHLECGECGRQFTHRKTWQNHLKRHEAVRTGAFKCGTCGRAFGNRARLDRHVRSHTGERPFGCKYCDKRFYDRHQQQRHTERHFRDQECSCEICGETFPGAKKRDQHKVEQHLRGPELEAFLARKSRQRSYKKPAVLKDKKCPFAGCDYIANTYGAMYVHKRTKHQPVHKCELCNKSYAFLNQLRVHMALHTGEKPYQCEICGRNFRRGFSYKEHMEMHNPEATYNCPTCNKSFKRPRYLQAHMLTHTAVRKFSCEICGSCYKTNGELKKHTKNKHGLDIVEEEVREIVIDADDTDISSFVVEYV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00104565;
90% Identity: iTF_00101127;
80% Identity: -