Aqua003859.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles quadriannulatus
Gene Symbol
-
Assembly
GCA_000349065.1
Location
KB665633.1:633897-638366[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 2.1e-06 0.0001 22.0 2.6 1 23 213 235 213 235 0.99
2 15 0.018 0.89 9.6 0.5 1 23 241 264 241 264 0.98
3 15 0.012 0.58 10.2 0.2 1 23 284 307 284 307 0.93
4 15 0.023 1.1 9.3 3.4 1 23 313 336 313 336 0.94
5 15 3.8e-05 0.0018 18.1 0.2 1 23 519 541 519 541 0.98
6 15 3.3e-05 0.0016 18.2 0.7 1 23 547 569 547 569 0.99
7 15 0.012 0.58 10.2 2.5 1 23 661 683 661 683 0.98
8 15 7.6e-06 0.00037 20.2 0.6 1 23 689 711 689 711 0.99
9 15 0.00018 0.0089 15.9 0.0 1 23 802 824 802 824 0.95
10 15 0.0012 0.057 13.4 3.4 1 22 830 851 830 854 0.90
11 15 5.9e-07 2.9e-05 23.7 0.8 1 23 1009 1031 1009 1031 0.99
12 15 0.00013 0.0066 16.3 4.0 1 21 1037 1057 1037 1059 0.94
13 15 0.00024 0.012 15.5 0.8 1 23 1294 1316 1294 1316 0.98
14 15 1.6e-06 7.9e-05 22.4 2.6 1 23 1322 1344 1322 1344 0.99
15 15 0.0027 0.13 12.2 1.0 2 23 1351 1373 1350 1373 0.96

Sequence Information

Coding Sequence
ATGGAGCTGAAGGCGGAGAAAAAAGACCACAACGACCACGATGAAAGCGGCGGTGGTGTACGGCGACACGCTGCAGCAGCAGCGGCAGCTGCTGCATCGGTCGCGATGGATGTCGAGGCGGCAGCGAATGGGGGCGAACAGTCGTCGGATCAGGAGATAGTGGAGGTCGGCATTGACGAGGATCACATCAAGTTTCTCACCAGCATGCACTCGGGCGACGAGGAGCCGTCGAGCGGGAGCCACCACCATCGCATGGTGGGTGGGGCGCCGCATCGCCCCGCCGCCGCCGCCGCCGCCTCGAATGGGGTCACAGGGAATGGGCGTGAAGGAGAGGATGGTGCCAGCAACGCCACCGGAGGGAAGCTGTACGGTGCGGCTCACCGGAATGGCGGTGTGCTTAACGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGTCGCCGCGAACATCCTATCGAAGACGGCACAGAGGTCATCGTTGCTTGCCACAGAACGCACGTACCAGTGTGACGTGTGCCCGCGGATCTTTCACCGGCCGGACCATCTGCGCTACCACATGCGCATCCACGAGAAGAACAACCCGTTCGAGTGCAAGCTGTGCTTTAGCGTGTTCGCGTCCGATCCCGCCTTTGCGCACCACATCCGGACGGAGCATGCCGGGATGGGGCTGGCCGACGCGTTGCCCCCGGTGCCGGAAACGGAGGCGAACTACTTCGCCTGCACGTACTGCGACAAAGCGTACGGCGACGGGGTCGAGCTGGAGGAGCACCTGCACCAGCAGCATTTGGGCGAGCGGCCGTACAAGTGCAACATGTGCCCGAAAGCGTTCATCCGGATGGATTTCCTGCAGTGCCACTACCTGAAGTACCACAGCTTCCACCCGATGGAGGACGAGGAGGACGAGGAGGGGGGTGGTGGTGAGGGCGAGGAGGAGGAGGAGGATGGGGAAGAGGAGGAGGAGGGAAACAATTACGGGCGGATGCAGCAACATCAGCAGCAGCATCAAGCGGACGCGAACCAGCAGTACGAGCATCGTGCCAAGCGGCCCCGCTTGATGGTGCGCAAGATCGAGGATTTGGTGGACGACCGGGGCAGCAGTGCGGCGCTGAAAGGCAGGTTTGGGGCGGTGTCGCGGCGTACCTCGCACACCGGCACGAGCATTTCGAGTGACGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNACGGGAGCGGACAGCAGCGATCAGCACCAGCGGTTCCTGCAGCGAAGGGAGGGTGGATCGGTGGGCGGTGGGCGTAGCCTGCTGCCGAGGCTGAGCGGGGTGCATGGCCGGTTTTTGGCCGCGATGGAGGAGCAACATTCGAAGCGGCTGGCGGCGGCAGCGGCGGCGGCGGCGGCGGTGGTGGAAGAGAGCGGCAAGCATCGGTGTCCGGTGTGTGATCGAGGGTTTGCCCGCGAACCGGAACTGATGCTGCACGTGCGATCGCATCCTGATTTGCCCACCTTCAAGTGTCCGCTGTGCGAGCTGACCTTCATCGGGTCGGACTATCTGAAGAATCATCTGAAAAAGCACGTGATCGGCAACGGGGAAGATCCGGGCGCACCGGGTGCGATCGATTTGAAGGTAAATCCTGCCGCCGACACGAAACCGACCGGCCGGCAACCGCCCGGTGGCGATGGTGGCTCGTCTCAGACCACGCTCCTGCCCTCCACCGCCAAGCTGCCCAAACCGATCATCACGTCCAAGCCGCCCTCGACCGGCATCTCGCTGCTGAAACCGATCGAGGAGCGCAAACCGCCCGACCACCACCAGCAGGAGTACTGCGTGAAGACGCCCGACGGCAAGTTCATGTGCACGGTGTGCGAGCGGCTCTTCTCGCACCAGCAGACGGTGCGCATCCACTTCCGCATCCACACGAACGAGAAGCCGTACAAGTGCGCCTTCTGCGACGAGTCGTACATCCGGTCGGACTATCTCGAGCGCCATCTGAAGGTGCACTTTAAGGATGGGATGCTGCCGGCGGCCGCCATCGCGAGCATGGCGGCGGCAGCCGCAGCGGCCGCATCGAGCGGGGGAAGTCGATCGGCTGCCTCCACGCCGCCGCCACCACCGGCACTGGCGACGGTGAAGGAGGATTTGGCGTACGCGGAGTCGAGTCCCTCCACGCCGGCGGCTGCTGGTACGGGGGGCTCCACCGGCAAACCGCTGATCGGGCGGGCCGGGCTGGCGCCGGAAAACTACCACTTTACCGAGTCGAACGACGGGCAGTTTGTGTGCAAGATCTGCGACGCCGTGTTCAGCCAGGTGGCCTTACTGCGCAAGCACGCGCTAGCGCACACGGAGGAGAAACCGTTCCACTGCGACATCTGCGACCGGTCGTTCAACCGGGTCGACTACCTGAAGGAACACTTCAAATCGAAGCGCCACCTGCAGCTGGTGGCGGAGGCGGCGGCCGCCGGTGGAGGTGCTGAAGGGGGGCCGACGACCGGCCCTACTGCCGCAGCTCGGCCGGACGAAGAGGAGGGCGATGATTCAACGATGGANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCCGAGCGCGAGGCGGGCGAGGTGGTCGAACCGGCGTCCCGGTCGGCGCTGGGTGAGTTCCATCGGTCCGATTACGAGCGCACGAGCGACGGGCGGTACAAGTGCAACCAGTGCGACAAGACGTTCGTGACGGCCGTCACGCTGAAGATGCACATCCGGCTGCACACGGGCGAGAAGCCGTACAAGTGCGACAAGTGCGACAAGGCGTTCATCCGCTCGGACTATCTGAAGACGCACGAGAAGTGCCACCGGCAGGAATCGTTCCTCAGCATGCTGTCGCTGAAGACGTCCAAGGAACCGAGCACCGCGTCCGAGGCGGGCGACTCCGATGCGGACGGTGGCTTGGAGCTTGGTGAGCTGAGCAGCAATCGGTCGTTGATGGACGCGGCCGGTGGGACGATGAACGGTGCGCGCGATCATGTTGGTGAGAATGGCAATGGTGTCGGAGGGCAGCTGAACGATGATACGGATGAGGAGGAAGGAGAAGAAGAGGCGGAAGAAGAGGAGGAGGATGAATCGGAAGAGAGCGAAGATGAGCAGGTTATTGAAGTGATGGTGAAGGAAGCGAGCTGCTCTGAAAGTGAAGAAGAGGACGAAGAGGAGGAAGATGAGGGCGAGGACGAGGAAGAGGATGAAGAAGATGGGGAGGAAGGGCAGCATGCGCTGTACCAATCGACCACCGACAACAGTACAAACCGAATCGCGACAAACACAACTGCCGCCAGCATCGACCGAAAGGAAGGCAAGAGCGCTAGCAAGCGAAAAAACCGACCAAAGGACTCGCGCACCCCGAACCGTCCGTCCCTGCCGGCCACGAGCGGGTGCGACAGTAGCAACAATGGCTACGAGGACGACAGCGCATCGCAGGCGAGTGGGCCGGTCTCGGCCGGCAGCCATGGTGGTGGTGCGTACGCCGGCTCGGAACTGCTGCCGAACGGGCAGAAGGGCAAGCACCGCTGTCCCATGTGCGACAAGCTGTTTGCGTGGCCAAAGTCGCTCAAGATCCATCTGCGCACGCACACGGGCGAGAAGCCGTACCGGTGCGACGTGTGCGGCAAGTGCTTCGGCCGCTCGGACAGCTTGCGCGGCCACAAGCGGACGCACGCCGACGACAAGCTAATACAGTGCCATTTGTGCGATGTGAGCTGCCCGAACGCGACCGAGCTGGTGCAGCATCAGTACACGGTGCACGGTCTGCAGCCGCTGGAGAGTTAG
Protein Sequence
MELKAEKKDHNDHDESGGGVRRHAAAAAAAAASVAMDVEAAANGGEQSSDQEIVEVGIDEDHIKFLTSMHSGDEEPSSGSHHHRMVGGAPHRPAAAAAASNGVTGNGREGEDGASNATGGKLYGAAHRNGGVLNGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVAANILSKTAQRSSLLATERTYQCDVCPRIFHRPDHLRYHMRIHEKNNPFECKLCFSVFASDPAFAHHIRTEHAGMGLADALPPVPETEANYFACTYCDKAYGDGVELEEHLHQQHLGERPYKCNMCPKAFIRMDFLQCHYLKYHSFHPMEDEEDEEGGGGEGEEEEEDGEEEEEGNNYGRMQQHQQQHQADANQQYEHRAKRPRLMVRKIEDLVDDRGSSAALKGRFGAVSRRTSHTGTSISSDXXXXXXXXXXXXXXXXTGADSSDQHQRFLQRREGGSVGGGRSLLPRLSGVHGRFLAAMEEQHSKRLAAAAAAAAAVVEESGKHRCPVCDRGFAREPELMLHVRSHPDLPTFKCPLCELTFIGSDYLKNHLKKHVIGNGEDPGAPGAIDLKVNPAADTKPTGRQPPGGDGGSSQTTLLPSTAKLPKPIITSKPPSTGISLLKPIEERKPPDHHQQEYCVKTPDGKFMCTVCERLFSHQQTVRIHFRIHTNEKPYKCAFCDESYIRSDYLERHLKVHFKDGMLPAAAIASMAAAAAAAASSGGSRSAASTPPPPPALATVKEDLAYAESSPSTPAAAGTGGSTGKPLIGRAGLAPENYHFTESNDGQFVCKICDAVFSQVALLRKHALAHTEEKPFHCDICDRSFNRVDYLKEHFKSKRHLQLVAEAAAAGGGAEGGPTTGPTAAARPDEEEGDDSTMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEREAGEVVEPASRSALGEFHRSDYERTSDGRYKCNQCDKTFVTAVTLKMHIRLHTGEKPYKCDKCDKAFIRSDYLKTHEKCHRQESFLSMLSLKTSKEPSTASEAGDSDADGGLELGELSSNRSLMDAAGGTMNGARDHVGENGNGVGGQLNDDTDEEEGEEEAEEEEEDESEESEDEQVIEVMVKEASCSESEEEDEEEEDEGEDEEEDEEDGEEGQHALYQSTTDNSTNRIATNTTAASIDRKEGKSASKRKNRPKDSRTPNRPSLPATSGCDSSNNGYEDDSASQASGPVSAGSHGGGAYAGSELLPNGQKGKHRCPMCDKLFAWPKSLKIHLRTHTGEKPYRCDVCGKCFGRSDSLRGHKRTHADDKLIQCHLCDVSCPNATELVQHQYTVHGLQPLES

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00101099;
90% Identity
-
80% Identity
-