Apun013240.1
Basic Information
- Insect
- Anopheles punctulatus
- Gene Symbol
- -
- Assembly
- GCA_000956255.1
- Location
- JXXA01002191.1:110-2263[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 4.6 3.8e+02 1.6 0.4 8 23 92 107 91 107 0.93 2 12 4.7 3.9e+02 1.6 0.4 12 23 282 293 280 293 0.85 3 12 0.00039 0.033 14.4 1.9 2 23 298 320 297 320 0.95 4 12 0.0018 0.15 12.4 1.4 1 23 329 351 329 352 0.96 5 12 2.7e-05 0.0023 18.1 0.8 1 23 359 381 359 381 0.98 6 12 0.00036 0.03 14.5 2.6 3 23 389 409 387 409 0.98 7 12 4e-06 0.00033 20.7 1.6 1 23 415 437 415 437 0.97 8 12 5 4.1e+02 1.5 0.4 3 23 458 480 457 480 0.93 9 12 6.7e-06 0.00055 20.0 3.6 1 23 484 507 484 507 0.97 10 12 0.015 1.2 9.4 0.7 1 23 513 535 513 535 0.96 11 12 4.4e-07 3.6e-05 23.7 1.1 1 23 541 563 541 563 0.98 12 12 0.0013 0.11 12.8 6.9 1 23 569 592 569 592 0.96
Sequence Information
- Coding Sequence
- ATGGAGGAGGTACCCGATCAATCACCTTTACCTAACTGTCCGATGGCCTCGTACCCAACATCGGCTCAGAAAATCCTACTACAACGATTTTGCCGACTTTGCATGCGGGAGAGTCCGTTCCTGCTCCCGTTCAGTGCGATGCTCAAGGAAACTACTCTCGCCGACATGCTTGACCGATTGTTGGGCGGTTTCAGGATTAAACAAACAGTCGAACTACCGAATGGTGTGTGTACAAACTGTCTGACAAAACTAGAGTACGCTTTTAGCGTTCAGAAGGAGTTTGTGCGCAACGAACAACGACTGCGACACTACAACCAGCATGGTGAGCTGCTGGAGAAACTGTTTGCCTTCCAATCGCACATCACGATCGTGAAGGAAAGGAGCGCTACACAATTAATTGCAGAAAACGACGAGGAGATACTCCAGGAAAGGATAAAGATTGATCCACAGTTCGAAGTACCCGGCATGTGTGCTGCGGAATCGAGCGCGGCAGCTACTTTTAAATCGATGGTACCACCCGGTGGCTGGGTTGTAATGGCTTGTGATTGTCCTTCCAAACCGTCGGCCCCGTCAACTCGCCTTACTGCAAAGCTCACCAAGCCGATACGACCGGCTGTGCTAAAGCGACCACGTCGCAATCGAGCGATTCTGCGGCAGGCTATTGCTGCCGAAACATCAGCCGGAGCTAGTGAAACTTCGATAGACCCTTGTAAGTGTTACGTATGCGGCAGAGTAATGGAATGTGAACAGGGATTGCGAGACCATCTTGTTGAGCACGTGGGTATGCTTCCGTACACGTGTGCACCATGTTCCGAGGCACAGGATACATCCAATCCCATTACCTCGCTGGCAATGTTGCAACGTCATTTTCGTATGCATTCGTACCCGTTGAAGTGTCCCTATTGTCCGCAACGATTTCGACAACACACATCCGTGTATGCCCACGTTCGCTATCGACACGAAATGTTCGATAATCCCGAAGGCTATACGTGCGACGTTTGTGGCGTTAAGATACGCTACCGTCCGTCGTTCATGTACCATATCCGTATGCATCATCACGAGCAGCGTGGAACGTACCGCTGTCAGTACTGTCAGCGTGTTTTTGGTACACGCGCACGACTGGAGCGCCACGAACGTGCGCATACCGGGGAGCGTCCATTTGGGTGCCATCTATGTCCAAAAACGTTCGCCCATGGGGGCCAGCTGACGACACACCTCTCACGACACAATAATGAACGGGGCCACCAGTGTGAACAGTGTGGCAAGGCGTTCTTCAACAAAGCGATGCTGCGGCAGCATCTAGAATCGCACGAAACGGTTGAGAGTCGGAAGGAAGTAGGcgcaaaagcgaaaacacGACAACAGCGACCATGTCCATTTCCGGGATGTACACATGTGGCTCGCACGTATCAAGCGTACTACATGCATCGGTTGCGACACGAGATGGCACACCGGTGTGAGGAGTGCGGTCGGCGCTTCGCACGATTGTGTGAGTTGCGACGACACGTGCGCATTTACCATTCGACGGACAAACCGTTTAAGTGTGAACCGTGCGACAAAACGTTCCTCAGCTCGCAGAGCTACCGGGAGCACATGGATGCGCATTCAAACGTACGACGTTTTGAGTGTGATATTTGCGATAAAAAGTTTGTCCGTCGAAGAAATCTTGTGAACCATCGAATGTCGCACACGAATAATCGGCCTTatcggtgcgatcggtgcgaCAGCACTTTCAAGTACAAGAGCGACTACAATCGTCACCGGAAGCATAAACATGAGCAAACGGAACAAGAGGAGGCAGAAGAAGTACTAGATCAGGGATTGCTAGAAGACGGTGAAGAGACCGTGAACGAGATTGTGCTGATGGCGGAGGATCCAATAATGGATGAGATTCTTGACCAGAGCGTTCAACAGGCCATTTTGTCGAAGGAGAACAATGAGTTGGACGGAAATACCTACGGGGAGGTGGTTGAAACTGTCGAAGAATCAATTGTCGTAGAGCAGCCTTTTGTCAGTATCGGGATTGATGAAGTGACCAAACAAGAGTATATAATCGAGTACATCAATCATGCTTGA
- Protein Sequence
- MEEVPDQSPLPNCPMASYPTSAQKILLQRFCRLCMRESPFLLPFSAMLKETTLADMLDRLLGGFRIKQTVELPNGVCTNCLTKLEYAFSVQKEFVRNEQRLRHYNQHGELLEKLFAFQSHITIVKERSATQLIAENDEEILQERIKIDPQFEVPGMCAAESSAAATFKSMVPPGGWVVMACDCPSKPSAPSTRLTAKLTKPIRPAVLKRPRRNRAILRQAIAAETSAGASETSIDPCKCYVCGRVMECEQGLRDHLVEHVGMLPYTCAPCSEAQDTSNPITSLAMLQRHFRMHSYPLKCPYCPQRFRQHTSVYAHVRYRHEMFDNPEGYTCDVCGVKIRYRPSFMYHIRMHHHEQRGTYRCQYCQRVFGTRARLERHERAHTGERPFGCHLCPKTFAHGGQLTTHLSRHNNERGHQCEQCGKAFFNKAMLRQHLESHETVESRKEVGAKAKTRQQRPCPFPGCTHVARTYQAYYMHRLRHEMAHRCEECGRRFARLCELRRHVRIYHSTDKPFKCEPCDKTFLSSQSYREHMDAHSNVRRFECDICDKKFVRRRNLVNHRMSHTNNRPYRCDRCDSTFKYKSDYNRHRKHKHEQTEQEEAEEVLDQGLLEDGEETVNEIVLMAEDPIMDEILDQSVQQAILSKENNELDGNTYGEVVETVEESIVVEQPFVSIGIDEVTKQEYIIEYINHA
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00103185; iTF_00100512; iTF_00099224;
- 90% Identity
- iTF_00103185; iTF_00100512;
- 80% Identity
- -