Apun003582.1
Basic Information
- Insect
- Anopheles punctulatus
- Gene Symbol
- -
- Assembly
- GCA_000956255.1
- Location
- JXXA01011501.1:294-4293[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 8.7 7.2e+02 0.7 0.9 9 23 232 247 215 247 0.79 2 14 0.14 11 6.4 0.5 2 23 255 276 254 276 0.94 3 14 6.5e-05 0.0054 16.9 4.0 1 23 307 330 307 330 0.97 4 14 0.012 0.97 9.8 1.1 3 23 337 357 335 357 0.94 5 14 1.9e-05 0.0016 18.6 2.8 1 23 361 383 361 383 0.97 6 14 3.5 2.9e+02 2.0 0.4 9 23 648 663 630 663 0.76 7 14 0.0008 0.066 13.5 0.1 2 23 671 692 670 692 0.97 8 14 0.083 6.9 7.1 0.6 1 23 698 718 698 718 0.88 9 14 0.001 0.084 13.1 1.1 1 23 723 746 723 746 0.97 10 14 0.003 0.25 11.6 0.9 2 23 752 773 751 773 0.96 11 14 5.2e-05 0.0043 17.2 3.3 1 23 777 799 777 799 0.98 12 14 0.11 9.5 6.7 0.2 2 23 810 832 809 832 0.95 13 14 7.5e-06 0.00062 19.8 0.3 3 20 840 857 839 859 0.94 14 14 3.8e-05 0.0031 17.6 1.2 1 21 868 888 868 889 0.93
Sequence Information
- Coding Sequence
- ATGTCCATGGAAACGAAGTGCGATGTTTGTTTATCCACGACGGAAAGCGAATACAAGGAGCTTTTCGTCGAAAAGCATGTGCATATGGTCGAGATCGTAGCGAAACACCTGTGGTTCGAAgTGAAGCAAACAGCCGAAGGCAACTTCCTATGCACAAGGTGCTGGTCAGCTTTGGATGAATTCCACCAGTTTTACTGTGCTGTTGAGGGGGTTCGTGAACAACTGGAACTGTCCATTCTTGAAACCTCTGAATACGTTGTCTCCACGGACAACAAAGTGAACGAAGAGGTGTGCGACAGTGGTGGACCCAAGTATAATACGGAGTTTCTCGAGATAAAAGCTGAACCATTAGAATCACTGGACACCATCGAACCGGAGGACACGAACTGTTCCGGTGAGAAACCACTGCACTGCGCGTACGTGAAGTGTGAGGAAACGGTCGAATCGGATCCGACCGCTCTCTGGTCCGGCGATGAGGACGCTTGCAAATCCGATTCTTCGTCCGGCGACGAAAAGCGCACCAGGGGCCGCGAGCGAAAGCTCCACAAAAAACCTTCGCCGGTGAGCGAGGAGGCGAGGAAAGAGAAGGCGGAAGCTCAACGCGTGGAAGACGAGGGTTTGTTGCGGTTTTATCGACGGATCGTGTGCGAGGTGTGCGACAATCAGCGGATGATGGTGGGCGAGCCGCAGATCGATTTCGGCACGTGGCGCGCGTTGCTGCGCCACACGAAGGAAGTGCACCGGCACGACAAGGTGTACGTGAAGTGTCCGGTGTGCGAGATGAAGATGCGTACGAAGCagacgctgctgcagcacaagGACTGGCACGAGAATCCGGAAAAGTATCGATGCGAGCTGTGCGGCGAGATACACCAGAACATGAAGGAGCACATGCAGAACAAGCACCAGGAGCGCCAGTTTTGTTGCGATGTGTGCGGCAAAAAGTTCCCCTTCAAGAAGCGGCTCACGGTGCACATGAAGAAGATGCACGTCGAGAAGGACATCATCTGCGAACATTGCCAGAAACCtTTCACGAAATACACCATCGAGGATCACAAACGATCGGTGCATACGGCGCGCTTCGTGTGTGAACATTGCCCGAAAACTTTCAACAGTCGATTCCGGTTGCGGCAGCACATGGAGGAGCACGACGAAACGACCACTGCCCATGAACAGAATCGTGAAACTTGTGCAATGATGGAAACGACGGCCGGGGAGCATCGGAAGTGCACTACGTGCCTCTGCACGAATGCATCGGATTATCTGAGCATTTTCGCCGAGGAAAACCGAACGAAGAATATCGCGCAGATTGTGGCCAAACATCTGTGGTTTGAGGTGACACCCGTCGAGGACGAAAGTCAGTGGATATGCACACGCTGCTGGATTGCGCTCGAAGCATTCCACAGCTTCTACCGCATCATCGAACAATCGCGCGAGCAGCAGACTGATCTCCCCGGCCACGACAGCCACGATAAGAAGCGTTCTGGTACGCCGCCGGGTGTCAATATTACGGGCGGTCCAGCTTACAATACCGAATTTCTCGAAATCAAAGGCGAACCGGTGGACGACGAGGAAGGggaggacgaggaagaggaggaagatgaagatgaaaatggTAGCTTAAGCGGCGACCGAATGATACCGGACGATGAGATCAAGAGTGAGGACGAATCGTCGCAGGGGGGAAGTGCGAATGAAAGCGACGCCTCGTCGAGAGTGGTGAGGGGAAGAAAGAAGGGACGCCGAACCCGTCCGTCGACCGGTGGGCAGAAGGGTGGCGCAGCGTTAGGCGGCGACGAGGATACGCGGTTGGCGAAGCGAAGGGCAGGCGGACGCTTTCCATCTCACCCGGAGGAGGATAAGAGCATACTGGAGTTTTACAAGCGGATCGTGTGCGAGGTGTGCGACAACAAGCGCATGATGGTGGGCGAACCGCTGATCGAGTACGCGACGTGGGGCGAGCTGTTGCGGCACACGAAGGAACAGCACGGCCACTACAAGATCTTCGTCCAGTGTCCGGTGTGCGAGATGAAGCTTCGCACGAAGGTGACGCTGGTGCAGCACATGGACATGCACCTGCATCCGGACAAGTATCGGTGCGAAGTGTGCGGCGAGGTGTACCAGAACATGAAAGAGCACATGCAGAACAAGCACGAGGAGCGTCAGTTCAGCTGCGATCTGTGCGGCAGCCGGTTCCCGTTCAAGAAGCGGCTGGTGGTGCACATGAAGAAGATGCACGCGGAGAAGAACGTCACGTGCGACCAGTGCCAGAAATCTTTCACAAAGTACACGATCGAGGACCACCGGCGTTCGGTGCATATGGCGCGGTTCGTGTGCGAACACTGCCCGAAAACGTTCAAGATCCGGTTCCGGTTACAGAAACACATGCAGGAGCACGACAAAAGCCTGCGCATCTCGACGTGCGTACCGTGCCCGACGTGCGGACAGGTAATGGGCGACAAGTACATCCTCCGGCAGCACATCCGGCATATGCACGCCGAACAGCAGGCCGTCGACTGCGAGACGTGCGGCAAAACGttcaaaaacaatcgcaacctGAAGGTGCACCTGGCGAACGTGTGCATGAAACCGGTACTGCTACATCCGTGCGTTATCTGCGGGAAAGGCTTCCGGCACAAGAACAAGCTGAAGGATCACATGACGTCCTGTGCCCCGAATTGA
- Protein Sequence
- MSMETKCDVCLSTTESEYKELFVEKHVHMVEIVAKHLWFEVKQTAEGNFLCTRCWSALDEFHQFYCAVEGVREQLELSILETSEYVVSTDNKVNEEVCDSGGPKYNTEFLEIKAEPLESLDTIEPEDTNCSGEKPLHCAYVKCEETVESDPTALWSGDEDACKSDSSSGDEKRTRGRERKLHKKPSPVSEEARKEKAEAQRVEDEGLLRFYRRIVCEVCDNQRMMVGEPQIDFGTWRALLRHTKEVHRHDKVYVKCPVCEMKMRTKQTLLQHKDWHENPEKYRCELCGEIHQNMKEHMQNKHQERQFCCDVCGKKFPFKKRLTVHMKKMHVEKDIICEHCQKPFTKYTIEDHKRSVHTARFVCEHCPKTFNSRFRLRQHMEEHDETTTAHEQNRETCAMMETTAGEHRKCTTCLCTNASDYLSIFAEENRTKNIAQIVAKHLWFEVTPVEDESQWICTRCWIALEAFHSFYRIIEQSREQQTDLPGHDSHDKKRSGTPPGVNITGGPAYNTEFLEIKGEPVDDEEGEDEEEEEDEDENGSLSGDRMIPDDEIKSEDESSQGGSANESDASSRVVRGRKKGRRTRPSTGGQKGGAALGGDEDTRLAKRRAGGRFPSHPEEDKSILEFYKRIVCEVCDNKRMMVGEPLIEYATWGELLRHTKEQHGHYKIFVQCPVCEMKLRTKVTLVQHMDMHLHPDKYRCEVCGEVYQNMKEHMQNKHEERQFSCDLCGSRFPFKKRLVVHMKKMHAEKNVTCDQCQKSFTKYTIEDHRRSVHMARFVCEHCPKTFKIRFRLQKHMQEHDKSLRISTCVPCPTCGQVMGDKYILRQHIRHMHAEQQAVDCETCGKTFKNNRNLKVHLANVCMKPVLLHPCVICGKGFRHKNKLKDHMTSCAPN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -