Basic Information

Gene Symbol
ZNF236
Assembly
GCA_000956255.1
Location
JXXA01003484.1:5978-8098[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.19 16 5.9 0.4 2 23 245 267 245 267 0.92
2 12 0.062 5.1 7.5 0.2 3 19 301 317 299 320 0.92
3 12 0.0087 0.71 10.2 1.2 1 23 324 346 324 346 0.98
4 12 5.1e-08 4.2e-06 26.7 2.9 2 23 355 376 354 376 0.98
5 12 0.00038 0.032 14.5 1.0 2 23 415 437 415 437 0.95
6 12 0.33 27 5.2 1.8 3 23 447 467 445 467 0.87
7 12 0.00014 0.011 15.8 0.8 2 23 488 510 488 510 0.93
8 12 0.0016 0.13 12.5 1.9 1 23 517 540 517 540 0.94
9 12 0.00078 0.065 13.5 3.2 1 23 547 569 547 569 0.97
10 12 5.8e-05 0.0048 17.0 3.2 1 23 575 597 575 597 0.97
11 12 8e-06 0.00066 19.7 1.4 1 23 603 625 603 625 0.98
12 12 0.0011 0.094 13.0 2.1 1 23 631 654 631 654 0.96

Sequence Information

Coding Sequence
ATGCCTCCTGAAGCTGGTGAAACGATAGAGTTGACTGAGAGAACGTGTCGATTATGCTTGGGCAACCAGGAAGAGCTGATGCCGATGGAGTCTTCGTTGACGCCGAGCGAGAAGACCAACATCATTGAAAGGCTGCTAAAAATCAACCTGGATTCGAACTGGCCTTTCCAAAGTGCATGTCACAAATGTATCATGAAGGTCCAGTTGATCGAGAGCATACGCGTGCACTTCGATGAGAAAAACCGCTTCTTCGATGTGATGTTTACGCAATACAATCGAATGCATTATCCTCAGAGAAGATCGTCAAACAAGGGCGCAATCCAAGAAGATTCGAATAGCAGCGTATCCTCGTCGGAATACGTGATTGAAtcagtggtggtggaaaagccCGATCTCGAAGATGTACCACCGGATGTGCTGCTGAAGGCGGCAGACGAAAATTTGGATATGATAATCAAACAGGAGGAGCTTGACCATGAGCCGCTGGAAATGTACGAAAATTTCATGCTAGACGAGGACGCACTGGTAGAGGAAGACAAGGACGAGATAGAGGATAGTATGGTGGAGGAATTCATAGAGGAACATATCGTGGAAATGGATAATGAGCACGAGCAGATCGACCCGTCGGCGGCCATCGCTTCGGAACAACAAAGTAACGACGCGTACGAAATGCAGGAAGAACTGGACGAATCGATTTATGGCGAGGACGGTTTCTACGACCCGTCGATCAATCGGTGCCAACTGTGCCTGGATACGTTTCCATCTGATAGTCAGTTGCAGACTCATCTGGAAGAGACACATCAAGACGTGCTGCCATTCCACTGCAGCAAATGCTTGCTGTATATTGACGAAATCGGTGAAGTAAATGTGCATCTAATATCGCATCAGTATGCGTACGGGTGTCTTTACTGCTCGCAACGATACAACAGTGAAGAGCTGCTGCAAAAGCACAATGAAACCTGTTGCAAGTATCGTTGCCAGTACTGTACGGCCGAGTTCGATATTATGGCCCATCTGAACGCGCACAAGAAGCTACACAAGGCGCAACAGCGAGCgctaaacaaatgcaaatcgtGCGGCAAAACGTTCTCAATGTCAAGCAACTTGCAGCGGCATCTGCGCACGCATCGCGCCTGCAAGCTCGACCACATGGAACGGAAAAAGAGAACCCGCGCTCTCGCGCAGGAGCAGAAAGCTGAGATGGAGTCAAAAAATTTCGAAGTGTTGATGAGAAACTTGCGCGTCTGTCAGGTGTGCAACGAGAAGTTCGAAAGCAACTGCTACCTGGCGCGTCACATCGAACGCGAACACTCGGAGTTTAGTTTCCCGCTGTACGGGTGCGACATCTGCCCGAAGAAGTTCACCGCGTTCGACAAATGCATCCGCCACCGGGCGTACCATCGGCGATCGATGAAAAAACCGGACGCAACGCCGAACGGAAAGAAACCGGAGGGCAGACCGACGTGCAAAATCTGTAACAAAGAGTTCCGTATGGATTCGCAGCTGCTGCGGCACCTGTCGGAGGATCACGCACTATCGCTGGAGCTGTTCGAGTGCGATCAGTGCGCGCGCAAGTTCTCAACCGAGCTGAAGCTGCGCAAGCACCAGTACAACAGCCACCGGACGAACAAAACGCTGTACGTGTGTTCGCACTGCGGGCAGAAGTTTGAGAAGAAGCTAACGCTGAAGGATCACGAGACGAAGCATCTCGGAACGCCCGCGTACAGGTGCGAGCTGTGCGACAAGCAGTTCATCCACAAGCACAGCCTCGATCGGCACGCGCTCGTGCACAGCGACGAGAAGCAGTTTTCGTGCGACTTTTGCGAGAAAAAGTTCAAGCGCAACACGGCGCTGGTAATTCACCGGCGGATACATACGGGCGAGAAGCCGTACCACTGCGAACCGTGCAACATGCGGTTCATCGATTCCAGCACGCTGATCAAGCACCGCCAGCGGCAGCACCCGAAACAGGAGTGA
Protein Sequence
MPPEAGETIELTERTCRLCLGNQEELMPMESSLTPSEKTNIIERLLKINLDSNWPFQSACHKCIMKVQLIESIRVHFDEKNRFFDVMFTQYNRMHYPQRRSSNKGAIQEDSNSSVSSSEYVIESVVVEKPDLEDVPPDVLLKAADENLDMIIKQEELDHEPLEMYENFMLDEDALVEEDKDEIEDSMVEEFIEEHIVEMDNEHEQIDPSAAIASEQQSNDAYEMQEELDESIYGEDGFYDPSINRCQLCLDTFPSDSQLQTHLEETHQDVLPFHCSKCLLYIDEIGEVNVHLISHQYAYGCLYCSQRYNSEELLQKHNETCCKYRCQYCTAEFDIMAHLNAHKKLHKAQQRALNKCKSCGKTFSMSSNLQRHLRTHRACKLDHMERKKRTRALAQEQKAEMESKNFEVLMRNLRVCQVCNEKFESNCYLARHIEREHSEFSFPLYGCDICPKKFTAFDKCIRHRAYHRRSMKKPDATPNGKKPEGRPTCKICNKEFRMDSQLLRHLSEDHALSLELFECDQCARKFSTELKLRKHQYNSHRTNKTLYVCSHCGQKFEKKLTLKDHETKHLGTPAYRCELCDKQFIHKHSLDRHALVHSDEKQFSCDFCEKKFKRNTALVIHRRIHTGEKPYHCEPCNMRFIDSSTLIKHRQRQHPKQE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00103284; iTF_00100507;
90% Identity
iTF_00103284;
80% Identity
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