Aplu005527.1
Basic Information
- Insect
- Anopheles plumbeus
- Gene Symbol
- -
- Assembly
- GCA_034621735.1
- Location
- JAOEFI010000004.1:18716504-18722187[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.23 21 5.9 0.5 3 23 372 394 370 394 0.91 2 10 0.00057 0.051 14.1 1.0 2 21 600 619 599 620 0.95 3 10 0.099 8.8 7.1 0.3 1 23 640 663 640 663 0.93 4 10 0.42 37 5.1 2.5 1 23 668 692 668 692 0.91 5 10 1.6 1.4e+02 3.3 0.6 3 23 710 731 709 731 0.94 6 10 0.003 0.27 11.9 0.1 1 21 736 756 736 757 0.95 7 10 0.48 42 4.9 0.2 2 17 998 1013 997 1019 0.82 8 10 0.0031 0.28 11.8 1.6 2 23 1039 1059 1038 1059 0.92 9 10 8.3e-06 0.00073 19.9 0.1 1 23 1065 1088 1065 1088 0.93 10 10 0.14 12 6.6 0.5 2 12 1143 1153 1142 1154 0.89
Sequence Information
- Coding Sequence
- ATGCTACACGAGGACGACACCGAACTGGATGACACCCATCTCTGCATTAAGTGTGGCAGCACCGTGGTGGGAATTGAAAATTACATTAAGCACCGTAAGGTAAACTGCCCTCCCCGGCAAGTCCTGAAGTCCGCCGCGCACGGTGACGATGGTGCCtccgttgttggtggtggatcGGGCGGTGAAGGCACGATTGGCAACGCCGATCAACCGGCGGTGGAACTGCGCGTCAGCACGGCGTCGACGGGCGCACCGTCGACGTCCTATGGGACGTCGTATGACTTTAGCGAACCAGCCAAGGAACAGGAGCGCCACAAGAAAGCCCCGAACTATGACTATCAGAACTACGAGCTAGAGCCACAcgctcatcatcaccaccaccaccgggccgaCGGCTCGAAAGCGGCCGACTACAAGAGCGTCGTGAATTACGAGTACGACCTGGGAGCGGATTTGTTCTTTATGTCGCTCGAGCTGCAGAGCATCAACAATCAGAAGACGGCGGCCAGCCTGTCGACCGGGCAGGGGCATGCCGGTGGGACTGCCACTGTCACGGGGAGTGCCGGCGGAGGACCCGGTTGCAGTTCTGCGCCAAAGATGGGCGCACTGTCGCAGCACAGGCCGAAGCCTCGTAAGCTCCTTGCCCCGCTCGCTCCCCCAGACCCCCCGGACCAGCCGCCGCATCAGCTTCCGGACGATTGGCTGGCGACACCGAACGAGTCCGATAGGCTCATGAAAGCTGTCAGCGATATCAGTGGGCATAAAAAGATGGACCTGTATCCGATATTCCACCAGGAGTCGTCGGACGAGGACAGTGACGACGCGGATGAGGAGGGATACGATGCGCCACCCCGGACGCACACCGGCGGCAAGTGGAAACCGGAAAATCGTCCCTCACCGAACGCGCTGGGTCGTTCGGCGCCGTGGCGCCACTGGCCACCGGAGCCACCCGAGAAGTCGCTCGACACActggaggaggacgacgagtTCAAGAGCttgtcgccaccgccggggcACACCCGGGGCAAGTGGGTGCCCGGTTCGAAGATCCCCCGGCTCGAGTACAAGCCGGCCGACGAGCCGGTGGCACGCAGCTACGAGGACAACTACTGGTGCAGCATCTGCAACCGGCGGCTGGCGTCTCGGTTCGTGTACGAGCGCCACCTGAAATCAAATCTGCACCTCAAGCGGGCCCAGGAGGAAAGCGAACTGGAACGTGCCGTGAGGCCACTGTACGCGAACGAACTATCGAAGCAGTTGGCGCCGGGTCCCCAGCCCTCCGGGAGTTGCCCGGCGAAGGACGGCGAGGACCAACCGGTGCGTGCCGGCTCGGTGGAACACGCTTGTCAATCGAACGATCCGCCCGGGGGGAAGGTTAAACGGAAACGCAAATGTTACTACACGAAGTGCACCGTCTGCAAGACGCGACTTCCGACGCACCTTCTCGGGAAGCACCTGATTTCCCGGTACCACTACCGCCGGATGCTGAACCACCCGCAGCAGTGCTTCGACATCGTGCTGAAGAACATGCACCGCATCGTGCTGGAGTCCCCGTTCCAGTGTGCCCCTTGCCGGTTCTACGCCAACGGGGAGGCGCACTTCATGGCCCACTGGAACTCGGCCGAGCACGAGCGGCGCGTGGCGCAGCCCGGTGGCAAGTTCTGGTGCAGCTTCTGCAAGTTCGAGTGCGAGGCCAGCTTCCAGATGGCGGAGCATCTGCGCGGTGCGAACCACCGCGAGGTGATCGCCGTGATCAACCGCTCCGTGCCGATCATCATACGCAAGGTCACGCGCATCCGGTGCGACTTTTGCGAGCAAGAGTTTCGCTACAACGCCGAACTGCGGCGCCACCAACGGCACTGCAGTAAGATCAGCGcggaagcgatcgaacggGTGCGCACCAGGGTCCAGAATACGTTCCTCTGCGAGCTGTGCAGTGCGACCTTCCCCAATCAAATGCGGCTGCTCCAGCACGGCCAAAAACTGCACCGTCTGGCACACTACTACTGCTCCATTTGCGAGTGTACGTTCGGGACGGCGCTGGAATCGATGCGACATCGGCGCACCTCGCGTCACAAGGTTATGTCGGcccggaagaggaaaaagacgAACCTGGCGCGTAAGATCTGCCCCATTTGTAGGACGGAGCTGGGGGACGTTCTGGAGCTGAAGCATCACATCGCTAGCTGCCATCCGGAAGTGAAGTACAACTGTCCCCGGTGTGGCGAGTGTTTCGTCCTGGCGCAGGAACTCGGCAGACACGTACGTGAcaaaaattgtacatttttcaattcctccACATCgccaccggtggcggcggatgTGCTGGGGCCGCCGTCAACTTCGCCCTCGGGGCCACTCACGGCGACAGATTTGCTCTCGATTCCGGGCCCGTCTGCGACTCATCATGGCCCACCGGCAACTGCACTTCCGGCCGGGGGCGCGCGGCCCACATCGGAGGCGCAAActtcgccatcgtcatcagcaaCCCGGTCGCATCTTCCCGGcacaaattcaattatctcaaatgattcaattaaagTAAATATGAATGATCGTAAACTAGGCAAGGAGTCACAGCTGTACCCGGCGCCGGTGGCAACGCCGGGCCCGCCGCCGTCCCGGCACGAATCGGCACCGGCCAAGGGTGACAATGCATCCGCCCGGGCGGCCCAGGCCACAGCTGATGAGCTTGCGAAAGcaccacccggCGATGGAGCAACGTATGGAATTAAATTGGACTCATCGGCACCGGCCACAACAACATCAAGCAACACCGCGCCGGCAAGGATCCGATACCGGGCGGTCCACGGCGAGCCATCGACGGCGGCATCCAATTCGGATTGTGATAATGCTGTCGCCGTGCGCAGCAGCCCGCAGGCGTCAGCAGAAATCTTTTTCGCCATGGCTAATAATGCGTCCGAGAATAATACTGTTTACGTTGATGAAATTGTTGGCACCATCGGCGAGGACGGTTCGGTCGTTTGCTGGCAGTGTAAAATATGCCCATTCAGCACATCATCGCAGGCCGAATTTCTGTTTCACGAAATTTTGCACTCATCAAAGTTGGATGACAAAGCAAAGTCGTCCCCATCGGCCCCCCGCCCGAAGCTCACCTGCCCCCTCTGTGGGAAAGCGTTCTCGAAGGCTTCCCTGCGCTGCCACCTGCGTCAGCACACCGACGAACGGCTCTTCCCCTGCCCGCTCTGCCCGATGGCGTTCACGCGGAAGGCCAATCTCAAAAATCACACTGATAACATTCACAACCGGAAACCGGCGGCCACGGTGACACTGCCCCGGAATACCAGTGAAAATGCCACCCcgaaagaggaggaggaggaggaggaggtcgGTTCATCCAACCCCAGCAGTACCACCAGCAGCCCTACCAGCTCCGGCCGGCCACAGCAGCAAGCCCGTCGGTCCGTTTGCACCACTTgcgggaaaacgttcgccaaTCGGTAG
- Protein Sequence
- MLHEDDTELDDTHLCIKCGSTVVGIENYIKHRKVNCPPRQVLKSAAHGDDGASVVGGGSGGEGTIGNADQPAVELRVSTASTGAPSTSYGTSYDFSEPAKEQERHKKAPNYDYQNYELEPHAHHHHHHRADGSKAADYKSVVNYEYDLGADLFFMSLELQSINNQKTAASLSTGQGHAGGTATVTGSAGGGPGCSSAPKMGALSQHRPKPRKLLAPLAPPDPPDQPPHQLPDDWLATPNESDRLMKAVSDISGHKKMDLYPIFHQESSDEDSDDADEEGYDAPPRTHTGGKWKPENRPSPNALGRSAPWRHWPPEPPEKSLDTLEEDDEFKSLSPPPGHTRGKWVPGSKIPRLEYKPADEPVARSYEDNYWCSICNRRLASRFVYERHLKSNLHLKRAQEESELERAVRPLYANELSKQLAPGPQPSGSCPAKDGEDQPVRAGSVEHACQSNDPPGGKVKRKRKCYYTKCTVCKTRLPTHLLGKHLISRYHYRRMLNHPQQCFDIVLKNMHRIVLESPFQCAPCRFYANGEAHFMAHWNSAEHERRVAQPGGKFWCSFCKFECEASFQMAEHLRGANHREVIAVINRSVPIIIRKVTRIRCDFCEQEFRYNAELRRHQRHCSKISAEAIERVRTRVQNTFLCELCSATFPNQMRLLQHGQKLHRLAHYYCSICECTFGTALESMRHRRTSRHKVMSARKRKKTNLARKICPICRTELGDVLELKHHIASCHPEVKYNCPRCGECFVLAQELGRHVRDKNCTFFNSSTSPPVAADVLGPPSTSPSGPLTATDLLSIPGPSATHHGPPATALPAGGARPTSEAQTSPSSSATRSHLPGTNSIISNDSIKVNMNDRKLGKESQLYPAPVATPGPPPSRHESAPAKGDNASARAAQATADELAKAPPGDGATYGIKLDSSAPATTTSSNTAPARIRYRAVHGEPSTAASNSDCDNAVAVRSSPQASAEIFFAMANNASENNTVYVDEIVGTIGEDGSVVCWQCKICPFSTSSQAEFLFHEILHSSKLDDKAKSSPSAPRPKLTCPLCGKAFSKASLRCHLRQHTDERLFPCPLCPMAFTRKANLKNHTDNIHNRKPAATVTLPRNTSENATPKEEEEEEEVGSSNPSSTTSSPTSSGRPQQQARRSVCTTCGKTFANR
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -