Basic Information

Insect: Anopheles plumbeus
Gene Symbol: ush
Assembly: GCA_034621735.1
Location: JAOEFI010000004.1:19674505-19682165[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0056 0.5 11.0 0.0 1 20 342 361 342 363 0.92

2 9 0.00035 0.031 14.8 0.7 1 23 429 451 429 451 0.98

3 9 0.022 1.9 9.2 1.4 2 21 530 549 530 550 0.92

4 9 0.059 5.2 7.8 3.3 2 21 990 1009 989 1010 0.94

5 9 0.0027 0.24 12.0 0.0 3 21 1073 1091 1071 1092 0.91

6 9 0.0021 0.19 12.3 0.1 1 23 1142 1164 1142 1164 0.99

7 9 0.014 1.3 9.7 1.4 1 23 1170 1192 1170 1192 0.99

8 9 8.3 7.3e+02 1.0 4.7 1 23 1284 1307 1284 1307 0.95

9 9 0.11 9.8 6.9 0.4 2 21 1505 1524 1504 1525 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0056	0.5	11.0	0.0	1	20	342	361	342	363	0.92
2	9	0.00035	0.031	14.8	0.7	1	23	429	451	429	451	0.98
3	9	0.022	1.9	9.2	1.4	2	21	530	549	530	550	0.92
4	9	0.059	5.2	7.8	3.3	2	21	990	1009	989	1010	0.94
5	9	0.0027	0.24	12.0	0.0	3	21	1073	1091	1071	1092	0.91
6	9	0.0021	0.19	12.3	0.1	1	23	1142	1164	1142	1164	0.99
7	9	0.014	1.3	9.7	1.4	1	23	1170	1192	1170	1192	0.99
8	9	8.3	7.3e+02	1.0	4.7	1	23	1284	1307	1284	1307	0.95
9	9	0.11	9.8	6.9	0.4	2	21	1505	1524	1504	1525	0.93

Sequence Information

Coding Sequence: ATGACTTTCGCTGGAATTCGCTCGGGATCGGATCGTCGTGGCGCACGGGTGCGAATGGACCGGGCTGGCAAAGGAGACGATGAGGACGCGggcgacgagcagcagcagcagcagcagcagacacagGGTGCAGCGGATGAAAACGGTGGAACGCCGGCGGATGCTGCAGCCAGCAACAGCGATAACAGTGGCAGCCCCAGCAGtaccggcagcaccagcagcagcacaataGTTAACAACAAGGGCGGCAGTCGGagtagcagcagaagcagcagcagtaccaccGGAGGGGAAGCAGTCAGCATGAACGGCGGCACGACGGAGGGGGTGCTCGATGGTGCCCTGGAGGCGGAAATGAGCGACAGAAGTCCGTCGCGGCCAGCGACAACACCCTCGCCGGTGCTGGAGGATGCATCGTCGCGGACGCGAACAGCGGAATCGCCGAAGACGGGCGGGTCCGGGTCCGGGACCCTCCGGAGGGCGTCCGACGGTGGAGGGGACTGTTACGACGCGCGAGAAGAATCGTCGCCCGCCATGCGGGAAATCAAGCTCGAGCCAAACGTAGACCGGGACAGCCCGGAAGTAGACCCGGCAAGAGGTAGCTATAAATCGACCGGAATGTTGCCAGCTTCCGGCGCACAACGGAGGCCACCTTCGTCGGGCTCCTCGCACGGTCAGACACCATCACCGACGCCGGTGCCGATGCTTCGGCTGAACGTGGCCCTCGCGTCCGATCCGGCCGCCAATCCCGACGCGAAGGATCTCAAAAGTATCggcgccaccgacgccgcctTCGAGGAGAAGCAATctcaacagcaacaccagctaatgcagcagcagcaccagcaacaccacgCTCTCAACATGGCCATCGGACCACCGCCGGCACTCCAACAGGCGGCCGCGGTCTCCTCGACGGCGCTACTCTCTCGCAAGCCACCGCAGCAGGTGTCGCTCAAGGTCCCGGACGCCATTGCCGGCCCGTTGACGCTTCCGGTCGAGCTGCCGCCCCGGTTGCCGATGTACATCTGCGGACCGTGCGGGATTCGCTTCTCGTCCGCTTCGACCCTCGAAGCGCACCAGACGTACTACTGCTCCCACCGTAAAGACGCCGACGagggtggaggaggtggtgggggtgggggaggcacGGGATCGGCTAGTTCAGTGGGGAGTGGCGGTTCGGCGGGCGGGACTGGCACCGCCGGGGGTAAGAGTGCGCACCCGGGCGGTGACGGCACGCAGGGAGAGCCGCCGGCGAAGGCGGCCAAAACGGGCAAACAATACGCCTGCTCCCAGTGCTCGTACAGTGCGGACAAGAAGGTATCGCTCAATCGCCACATGCGCATGCACCAGTCGTCCCCCACCCCGTCGCCCGGCGCCATCGTCAACGGGGATGACGTCGCCAGTCACCACCATgctcagcaacagcagcagcagcaactacAGCTCATCCAGGCGCAAGCCGTCGCggcagccgccgccgttctgcatcagcagcagcagcagcaacaacaacaacaccaacagcagcagcaacaacaacagccattGCAGACGCAAGCGCCTGTGGCGCAAGTGGATCGGTACTGTTCCGATTGTGATATTCGATTTTCCAGCACCAAAACATATCGTGCGCACAAGCAACACTACTGCAGCTCGCGCCACCGTGAAGGGCAACAGTCGAACAACTCGACGCCGAAACCGTCGGGACAGAAGTCCGGCTCGCAGAGCCCACCGGATGTACCGAAAACTCCGCCGGTGTCCGCCGCCCAGCAACCGTTTCTGGCGCTGCCAACCAATCCCATCATCGTGATACCGTACTCTCTGATCCGGGGCGCCAGCGTCATACCGGGACTGCTATCGTCCCTTGCACCCGGAATCGCCAACCCGGAGTCGGCCTGTTTCATCTTCCAGAATGGAGCTCTGCAGCCGATCGCCATGTCGTTGGCGTCGCACGTACAGGCCGTTACGATGGCGGCCGCTATCGGGCCTACCGGTATCGAGGGTTCCGGAGGGCACGggcaacaccagcagccacagcagcagcagcaacagttgtCTGTTGGCTCCCGGTCGTCTCAGTCGGCTGGCGGCAtcatccagcagcaacagcagcaacagcaatcgCGCGGCCCGACGCCGAACATatcgaatgaaaatagttCCCACAGCAACACCGGAGGTGCCGGAGGAGGATCCTCCACCGGGGAAGTCCTGAAGGCGATCAACAAGCGAGACAACACTGCTAACAACAGGGAGTCAACCGGATCTACGCCACTGGATCTGTCCGTGAGGCGGCTTTCACCGGGCGTGCTAGGAGGCTTAAGTCTCCGGGAACGTTCCCTCTCGCTTTCGTCGGCCGTCTCGCTCGACCAGCGCATGGACTTCGACAGCCTGATGGAGGGCAAGGAGAACCTGTCCGTGAGCGGGGACTCGCTGACGCCGGAGCAAATCGTGTGCGCACCGTCCCTCCCGGGCAGTCCACCGCTCACTCCTTCGCCCAAGCGCCGCTCGCATAGTCCACGCGGTGGACCGGCCGGCTCGAACGCAAgtgcagcggccgccgccgtagcagccgctgcagccgccgtCGGTCAGCATGGACTCGGTGGTGGCGCCCTCTCGCTGTCTCCACTGaccctgcagcagcagctgatgcGTCCGCTGCTCCCGACCGACATCGCCCTACGCCTGTCGGCCGTAGGAGATCCGGGCGTCAACTTGAACCTGAACATCCTCCCCAACACGCACACCCTGCTCACGAAGCAGAGCGTCGAGCTGGCGTTGCGGCTCTCGTCGTCGGCCGGACCACCTGCGGGCCTCCCCGAGGGACTCAGCAAGCCGCAAATATCGCCCCACCTGAACAGCATCTCGCCGACGGGCGGCGGCACGAGTGCGGGTGCTGGCAGCGCCACCGTCCTGTCCGGCTCCACGCCCCAGATCTTCGTCAAGCAGGGCGACTCCAAGTGCAAGGAGTGCAATATCGTGTTCTGCAAGTACGAGAACTATCTGGCGCACAAGAAGCACTACTGCTCGGCCCGCAACCTCGACGACGGAGACCACGCAAAGATTAGTCCGCCCATCTCTCCGCAAGCGCTCGCCGCTGCAGGAGGAGGAccgccgggggtgggtggcccCGGGACGGTGCCCTCAAGTGCCCCCGGTGGAAGGccggccggtgctggcggaCCTGTCGCCTACCAGCAGCTGATTTGTGCCGCCTGTGGCATAAAATTCACCTCGCTGGATAATCTCACCGCGCACCAGATGTACTACTGTCCCAAGCGGATCGACGCCGCCCTGCCAGTGAATGCCAACCCGTCACCCGTTACTGCGCCAACGCCACACAAGGAACGCTGCTCCAAGTGTAAGAGCATGCACGAACCGGGACAGCCCTGCACGGTTGCGGGCCACGGTGCGTACAAGTGCCCGATCTGTGAGGTCATCAGCCCCAACTCGACCGAAGCCCGGCGACACATGGACACGCACGGCGGCGTCAAGGCATTCCGGTGCACGATCTGCCGGTACAAGGGCAACACACTACGTGGTATGCGCACGCACATCCGGATGCACTTCGACAAGAAAACAAGCGAGTTCAACGAGGAGAACTACATCACCTGCATACTGGAGGAGGACGGGATCGAGATCCCGCCGGCCGGGGCACAGAATGCCGCCGCCatggccgctgccgccgctgcgaTGGCGTCGCAGAAGTTTCTCCACCACGAGCCGGCCCCACCGCCCGACCCTGCCGGGTCACGCACCACTTCTCCGCCAACATCCGTCGGTAACGGAGGGGGAGCACTGGCCCCGGtaggcagcagtagcagcagcggatTGGTGCGGCATCACTGCGAGTTCTGTCAGTACAGCTCCGGCTACAGGATCAATGTGGCTAAACATATCAAGCACGTGCACGGAAGGGAGCGTTCGTCCACCGGCGGGTCTCCCCTGATCGGCGAAGGTGGCGAGTCGTTGCTGTACAACGGAGCGAGTGGGCCAGTCGAAGTTAGTGGAGCCATGCTGCGACCTCCGGTCGCTAGCACACCGGGTCTTAGTGCGGGCAATAGTCTTATTAAAACGGAACCGGAGGACGATCCTGGCGTGGATGCCAGCGACGAGCAGGACACGTCCGACATCAACGTGGACGTCGTGATGGAGGAACCGCTGGCTGAACCGATGGCCATCAAAAGCGAAACCATCGATCCACACATGCCCTCGCTGCACTCTCCCATCAGCTCCCCGGCGTcaccgccactaccaccaccatccctgACGATGGCCACCATGTCCCCCCTGATCGGAGGGCTCACGGCGGCCGCTTCCTTGAATCTGAAACCGAAATCTCACGCCGGTACGGTTCCACCGCCAGGTTCGTCGCCTGGCACGGTTCCAGTGCACCCGTCCCGCTCGTCGCCACTCGCCATGAAGACCCCGTCGCCGCCGACCTCGGACTCCGGCAGTTCTCCTGCACCCCCGCAGCACTTAACGCTCCCACCCGGGCCGAAATACTGCGACACGTGCAATATCACCTTCAACTACGCCAACACCTACATTGCGCACAAGAAGTTCTACTGCAAGGCCGCCACGGCCGTGGCAGCAGGTGTGTCGGGCAGCACCGGAGCGgtgggcggtggcggtgggcggAGTGCTTCCGCGTCGCCGAACCGTGCGACAACCGGTGGAGCCACCAGTCCGGCCGTGGCCGTCGCCGTTAACCGGGCGACTGAAACCTCCGTGTAA
Protein Sequence: MTFAGIRSGSDRRGARVRMDRAGKGDDEDAGDEQQQQQQQTQGAADENGGTPADAAASNSDNSGSPSSTGSTSSSTIVNNKGGSRSSSRSSSSTTGGEAVSMNGGTTEGVLDGALEAEMSDRSPSRPATTPSPVLEDASSRTRTAESPKTGGSGSGTLRRASDGGGDCYDAREESSPAMREIKLEPNVDRDSPEVDPARGSYKSTGMLPASGAQRRPPSSGSSHGQTPSPTPVPMLRLNVALASDPAANPDAKDLKSIGATDAAFEEKQSQQQHQLMQQQHQQHHALNMAIGPPPALQQAAAVSSTALLSRKPPQQVSLKVPDAIAGPLTLPVELPPRLPMYICGPCGIRFSSASTLEAHQTYYCSHRKDADEGGGGGGGGGGTGSASSVGSGGSAGGTGTAGGKSAHPGGDGTQGEPPAKAAKTGKQYACSQCSYSADKKVSLNRHMRMHQSSPTPSPGAIVNGDDVASHHHAQQQQQQQLQLIQAQAVAAAAAVLHQQQQQQQQQHQQQQQQQQPLQTQAPVAQVDRYCSDCDIRFSSTKTYRAHKQHYCSSRHREGQQSNNSTPKPSGQKSGSQSPPDVPKTPPVSAAQQPFLALPTNPIIVIPYSLIRGASVIPGLLSSLAPGIANPESACFIFQNGALQPIAMSLASHVQAVTMAAAIGPTGIEGSGGHGQHQQPQQQQQQLSVGSRSSQSAGGIIQQQQQQQQSRGPTPNISNENSSHSNTGGAGGGSSTGEVLKAINKRDNTANNRESTGSTPLDLSVRRLSPGVLGGLSLRERSLSLSSAVSLDQRMDFDSLMEGKENLSVSGDSLTPEQIVCAPSLPGSPPLTPSPKRRSHSPRGGPAGSNASAAAAAVAAAAAAVGQHGLGGGALSLSPLTLQQQLMRPLLPTDIALRLSAVGDPGVNLNLNILPNTHTLLTKQSVELALRLSSSAGPPAGLPEGLSKPQISPHLNSISPTGGGTSAGAGSATVLSGSTPQIFVKQGDSKCKECNIVFCKYENYLAHKKHYCSARNLDDGDHAKISPPISPQALAAAGGGPPGVGGPGTVPSSAPGGRPAGAGGPVAYQQLICAACGIKFTSLDNLTAHQMYYCPKRIDAALPVNANPSPVTAPTPHKERCSKCKSMHEPGQPCTVAGHGAYKCPICEVISPNSTEARRHMDTHGGVKAFRCTICRYKGNTLRGMRTHIRMHFDKKTSEFNEENYITCILEEDGIEIPPAGAQNAAAMAAAAAAMASQKFLHHEPAPPPDPAGSRTTSPPTSVGNGGGALAPVGSSSSSGLVRHHCEFCQYSSGYRINVAKHIKHVHGRERSSTGGSPLIGEGGESLLYNGASGPVEVSGAMLRPPVASTPGLSAGNSLIKTEPEDDPGVDASDEQDTSDINVDVVMEEPLAEPMAIKSETIDPHMPSLHSPISSPASPPLPPPSLTMATMSPLIGGLTAAASLNLKPKSHAGTVPPPGSSPGTVPVHPSRSSPLAMKTPSPPTSDSGSSPAPPQHLTLPPGPKYCDTCNITFNYANTYIAHKKFYCKAATAVAAGVSGSTGAVGGGGGRSASASPNRATTGGATSPAVAVAVNRATETSV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -