Aplu000214.1
Basic Information
- Insect
- Anopheles plumbeus
- Gene Symbol
- -
- Assembly
- GCA_034621735.1
- Location
- JAOEFI010000001.1:1802136-1804467[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.00018 0.016 15.7 1.5 6 23 240 257 240 257 0.99 2 13 0.029 2.6 8.8 1.1 1 20 263 282 263 286 0.88 3 13 0.00042 0.037 14.6 0.1 1 23 294 316 294 316 0.96 4 13 0.07 6.2 7.6 0.5 2 23 324 345 323 346 0.92 5 13 4.9 4.4e+02 1.8 0.4 2 23 399 421 398 421 0.85 6 13 9.6e-05 0.0085 16.6 0.9 1 20 454 473 454 477 0.94 7 13 0.00044 0.039 14.5 3.3 1 23 485 507 485 513 0.97 8 13 0.0007 0.062 13.9 3.0 2 23 516 538 516 538 0.96 9 13 2.2e-05 0.0019 18.6 0.3 2 23 545 566 544 566 0.96 10 13 2.3 2.1e+02 2.8 6.7 1 23 576 599 576 599 0.96 11 13 0.0079 0.7 10.5 1.0 2 23 606 627 605 628 0.94 12 13 0.0053 0.47 11.1 4.0 1 23 634 656 634 656 0.95 13 13 0.019 1.7 9.3 1.4 1 23 662 685 662 685 0.91
Sequence Information
- Coding Sequence
- ATGACGGAACCATCGTGCTTGGAGCCATGCCTTCTGTGTCGAGTAGTGTGCGTGAATCGGCTGCTAGAGACTCAGACGGCAGCATCGGGCTACCTGGTCCGGGATGttatttgtaaacatttttgGATATCGGAAGCCGACTGCAACGGTCGGTACGTTTGTATTTCGTGCTGGAGAGCGACGGAATCCTTTCATATGTTCTACAAGGAAATCGAACAGTCGCACAATCTCACAATCAAACACGAAGAGGAGCAGCAAGCGCAGGACGCAGATTACTTGACGCTGTTCGACTTTGAGATCCCGCAGTGCCGGATCTGGGAGCACGGATCGACCGAGAAATTGAATGAAGTGTACGTAAAGGAGAACCATTCCGAGGGCGAGTATGAGCTGGGCAACGGCGATCCTGACTGCACTGCCAAGCTCGGATCCGAAGAGGACTCGGACAAGGAATCGTCCCTACCGCTGTCCAAACGAAGGCGGGCGAAACCGGCTGGTCGTAGCGGAATCCGAAGGAAGTGGAATGATATGAAGACATGGCTGCCCGGAGTGGGAGTGACGCTGACCCGGTGCACCAGAGGCGTCCTCGAGGCCCAGTGTCACATGTGTGTGCGAGGTGCGGGCGGTGCGGCGAACGCGGCCGACGTACCGTTCGTGCGATTTGCTGCGTTGATGCGACACTTTACAGTAGAGCACGAAACTCCCGGGTACGCGGTGTGCTGCAACAAAAAGTACGCCCGGAGGAGATCGCTCAAGGCGCACATGCGTACGCACGGCAAGCAAACCATGTACCACTGCAACGAGTGCCGCGTGAAGTTTCGCAAGCAGGAAACCCTGGACGAGCACAATGCCCTTATCCACTTGTCTGACGCTGAGAAGCAGTTCAAGTGCGACAAGTGCCAGAAAGGGTTCGCCGACGAGGGCCTGCTCGGTTCACACCTGGAGTGgcacaagaaaatggaaaagaacatcGTGTGCAACTATTGTAACATTTTCTTTCCATCCGTACCAGCAATGctcaaacacaaaaccctACATCATCCATCGCCCGGGTCGTCCgacgttccgcttccggtggaacTGGCCCGCTCCGAGGATCCGGAGGATATGCTGCTCGTCAAGTCCGAgtaccggcggcggcgaacggCGGAAGAAATCGCCGAGCAGAATGCAGTCATCGAACGGTACTGCACGCTAAGCTGCCACCTGTGCGAGTACATCGCGCCCGTCTTCACCGACCTGAGGCAGCACGTGTTCGAGAAACACGGACTGCGTTCGTGCCGGGTGCTTTGCTGCGACCAGCCGTACAACAACCGGTTGCGCCTGTACGAGCACTGCCTGCGGCACGACAACCCGGACCGCTTCCGGTGCGAGGTGTGCGGCAAGCAGTATGCGAACAGCCGCAGCCTGATGCACCACCAGTGGCGTATACACACCCCGGCCGCCGAGCGCCCGTTCTGCTGCGACGTCTGCGGCGAAACGTTCGTGAAGGACTACCTGCTGAAAAAGCACCTGTCGTATCATCTGGCCAAGCACCAGAAGTTAAACTACTGCGACGAGTGCAAACGGTCGTTCACGACCTCGGCCGCCCTCAAGTGCCACCAGCAGACGTACCACGGTGCCATAGCCAGCTTGATATGCGACATCTGCGCGAAAGGTTTCAACAGTCGGTCGCTGCTGGAGAAGCATCGCTTGACGCACAGCGCCGAGGGCATCACGCAGCTCAAGCACCAGTGCGAACGGTGCAATAAATGGCTGAGGAACAAAAAGTCttaccagcagcaccgggcgCGCTGTCACGCCAACACCGGACCGGTGCAATGCATGTTCTGCGGCAAGGAGTCGGTCAACTCGGTGGCACTGAAGGCGCACGTGCACCTGCACCACGCTGTCCGGCCCGAGCACGCCTGCACGCACTGCTCCAAGCGCTTCAAGACGGCGCTCCGGTTACGCGAACACGAGGCTACCCATACCGGCACCGTGCTCTACCGCTGCCCGTGGTGCCCGCGGACCTTTGCCTGCGGCTCGAACATGTACAAGCACAAGAAGGCCGGACACCCGCTGGAGTGGGCCGCGGGCGTACGCAAGCGCTTCGGAGAGCGCTAG
- Protein Sequence
- MTEPSCLEPCLLCRVVCVNRLLETQTAASGYLVRDVICKHFWISEADCNGRYVCISCWRATESFHMFYKEIEQSHNLTIKHEEEQQAQDADYLTLFDFEIPQCRIWEHGSTEKLNEVYVKENHSEGEYELGNGDPDCTAKLGSEEDSDKESSLPLSKRRRAKPAGRSGIRRKWNDMKTWLPGVGVTLTRCTRGVLEAQCHMCVRGAGGAANAADVPFVRFAALMRHFTVEHETPGYAVCCNKKYARRRSLKAHMRTHGKQTMYHCNECRVKFRKQETLDEHNALIHLSDAEKQFKCDKCQKGFADEGLLGSHLEWHKKMEKNIVCNYCNIFFPSVPAMLKHKTLHHPSPGSSDVPLPVELARSEDPEDMLLVKSEYRRRRTAEEIAEQNAVIERYCTLSCHLCEYIAPVFTDLRQHVFEKHGLRSCRVLCCDQPYNNRLRLYEHCLRHDNPDRFRCEVCGKQYANSRSLMHHQWRIHTPAAERPFCCDVCGETFVKDYLLKKHLSYHLAKHQKLNYCDECKRSFTTSAALKCHQQTYHGAIASLICDICAKGFNSRSLLEKHRLTHSAEGITQLKHQCERCNKWLRNKKSYQQHRARCHANTGPVQCMFCGKESVNSVALKAHVHLHHAVRPEHACTHCSKRFKTALRLREHEATHTGTVLYRCPWCPRTFACGSNMYKHKKAGHPLEWAAGVRKRFGER
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -