Basic Information

Insect: Anopheles plumbeus
Gene Symbol: creA
Assembly: GCA_034621735.1
Location: JAOEFI010000004.1:25815198-25826067[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 2.8e-09 2.5e-07 30.9 0.2 2 23 179 200 178 200 0.97

2 6 8.6e-08 7.6e-06 26.2 0.5 1 23 206 228 206 228 0.97

3 6 3.8e-06 0.00034 21.0 3.2 1 23 234 256 234 256 0.98

4 6 7.8e-06 0.00069 20.0 1.5 1 23 262 284 262 284 0.97

5 6 1.2e-05 0.001 19.5 4.3 1 23 290 312 290 312 0.96

6 6 2.5e-06 0.00022 21.6 2.9 1 23 318 340 318 340 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	2.8e-09	2.5e-07	30.9	0.2	2	23	179	200	178	200	0.97
2	6	8.6e-08	7.6e-06	26.2	0.5	1	23	206	228	206	228	0.97
3	6	3.8e-06	0.00034	21.0	3.2	1	23	234	256	234	256	0.98
4	6	7.8e-06	0.00069	20.0	1.5	1	23	262	284	262	284	0.97
5	6	1.2e-05	0.001	19.5	4.3	1	23	290	312	290	312	0.96
6	6	2.5e-06	0.00022	21.6	2.9	1	23	318	340	318	340	0.98

Sequence Information

Coding Sequence: ATGATTCGACACCGGTTCGGACTCTACGACGAGATTACCGCCGTCAATGGGCGCACAGTGCGACACTGCAACTGGATCCGGTTCCTGCGAGTGTCGGAAACGTACGGCCCGCAGGTGAACGTGGTCTGCGCCAAGGTGAAAGGTGAACCGATCTACGAGATCGTGAAGCCGATCCCGTCGCACCAGGAGCTGGTCGTCTACTACCTGCCGGAGGGCCCCGAGGAGCTCTTCTTCATCCGGATGCGTAATCAGCTGTATCGGCAAACGATGGACTCGATCCTGGAAGATTCTCCACTGGACCTCTCGACGTCGCTCCTGTCGCGGGTCATGCTGCCGATCTCACCCCCGTCGGGCGCCGAGGACGAACACAAGTCGGTGTCGGGCGACGACTCGTCGATCTCGATCTCATCCGGGGCCAGCACCGGCGACCGATGCGACGGAGCGCTCGACCTGGAGCTGGCCGCGATCGCAACCGGCGCGTCCAGGACCTCCCCGAAGGCACGTCCGGCCGCGCGCTCCGAGCGGGCCATGCTGCCCTGCGAGGTCTGCGGCAAGGCCTTCGACCGTCCTAGTCTGCTGAAGCGACACATGCGCACGCACACCGGCGAAAAGCCGCACGTCTGCGGCGTCTGCGGCAAGGGCTTCAGCACTTCCAGCTCGCTCAATACCCACGTCCGGATACACTCGGGCGAGAAGCCGCACCAGTGTCAGGTGTGCGGCAAGCGGTTCACCGCCAGCTCCAACCTCTACTACCACCGCATGACGCACATAAAGgaaaaaccacacaaatgTAGCCTCTGCTCTAAATCCTTTCCGACGCCCGGTGATCTCAAGTCGCACACGTACGTCCACAACGGTTCCTGGCCCTTCAAGTGTCACATCTGCTCCCGTGGCTTCTCCAAGCAAACGAATCTCAAGAACCACCTCTTTCTGCACACCGGTGACAAGCCCCATGTCTGCGAGGTGTGCAAGAAGTCCTTTGCGCTCGCCTGCAACCTTAAAGCCCACATGAAAACCCACGAAGAAAGCAACTCGCCGGAGTCCGAGATCGATGTCGACAGTGACCTACGGAGtgatggagaagaaatcgGACCGCTGTTCAGCTACGAAAAGGTGGACGAACGACTATCGCGATATCACTGGAGACATTccaaaacggaaccgatcACGAGGAGTCGCTAA
Protein Sequence: MIRHRFGLYDEITAVNGRTVRHCNWIRFLRVSETYGPQVNVVCAKVKGEPIYEIVKPIPSHQELVVYYLPEGPEELFFIRMRNQLYRQTMDSILEDSPLDLSTSLLSRVMLPISPPSGAEDEHKSVSGDDSSISISSGASTGDRCDGALDLELAAIATGASRTSPKARPAARSERAMLPCEVCGKAFDRPSLLKRHMRTHTGEKPHVCGVCGKGFSTSSSLNTHVRIHSGEKPHQCQVCGKRFTASSNLYYHRMTHIKEKPHKCSLCSKSFPTPGDLKSHTYVHNGSWPFKCHICSRGFSKQTNLKNHLFLHTGDKPHVCEVCKKSFALACNLKAHMKTHEESNSPESEIDVDSDLRSDGEEIGPLFSYEKVDERLSRYHWRHSKTEPITRSR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00092327;
90% Identity: iTF_00093635;
80% Identity: -