Aplu007306.1
Basic Information
- Insect
- Anopheles plumbeus
- Gene Symbol
- -
- Assembly
- GCA_034621735.1
- Location
- JAOEFI010000006.1:9785129-9787572[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.0054 0.48 11.1 5.5 1 23 190 212 190 212 0.97 2 11 3e-05 0.0027 18.2 1.6 1 23 218 240 218 240 0.98 3 11 7.4e-05 0.0066 16.9 4.5 1 23 246 269 246 269 0.96 4 11 2.4e-05 0.0021 18.5 2.6 1 23 275 297 275 297 0.98 5 11 3.5e-05 0.0031 17.9 2.1 1 23 303 325 303 325 0.99 6 11 7.4e-05 0.0066 16.9 0.7 1 23 331 353 331 353 0.97 7 11 0.00021 0.019 15.5 1.3 1 23 361 384 361 384 0.97 8 11 0.00046 0.041 14.4 1.4 2 23 391 412 390 412 0.97 9 11 0.0087 0.77 10.4 0.7 1 23 418 440 418 440 0.97 10 11 0.00024 0.021 15.3 8.1 1 23 446 469 446 469 0.95 11 11 3.3e-07 2.9e-05 24.3 1.6 1 23 483 505 483 505 0.96
Sequence Information
- Coding Sequence
- ATGAAGCCCAAATCGGAATCCGGTTCGGGCATAAAAAAGTActtgaataaatcaaatcgTCAGCCACGAGAGATCGCCAATAAAGCAACAATTACACGCACTAGGAAGGGTGGTGAAGAAATCATGCCGGCACCGATTCAAATTGCTAAGCAAGAAAAACCTGACGACaatgacgacgaagacgactTGATGATGACTGCAACCGATACTGTGAACGATGCAGAAGAGGAAGGATGCTACTTCGTTGATCAGAAAGGGAACTACTACTTTCAGGCTACCGAGGACGCCGAACCGGTGCTGACGGCGGTAACCAACGAACCGTCAGGTTTTTCCGCTGTTGATGGTGAAGGtatgaaaattgaacaaaacggTGTAAGTTATGTCCTTGTAATGGATGATGGCGGGAACAAGTCGACCATTGTGGCCGACACAAATGACGCAGGCAACCTGGTGCCTGATGAGGATGAAATTTACGAATTCGCCGATTCGGACTTCCTCGTCGATGAACCGCCCACAAGTGAGAAAAGGacgcgcgggaaaaaggaaacattggCCGATGCAGCGGTACACATGTGCAACTACTGTAACTACACGACCAAGAAGATGTTTTTACTCTCACGTCACCTTAAAACGCACTCCGAGGACCGCCCGCACAAGTGTTCAGTGTGCGAGCGTGGCTTTAAGACGATGGCGTCGCTACAGAACCATGTTAACACGCACACCGGTACTAAGCCGCACCATTGCAAGAACTGTGACAACAGTTTCACGACTTCCGGGGAGTTGGTACGGCACATCCGTTACAAGCATACGCACGAGCGTCCACACAAGTGCACGGAGTGTGACTATTCCAGCGTGGAGCTGAGCAAACTGAAGCGCCACATCCGAACGCACACCGGGGAGAAACCGTTCCAGTGTCCGCACTGTACGTACGCCTCGCCGGATAAGTTTAAACTAACACGCCACCTGCGCATACACACGGGTGAAAAGCCGTACTCTTGCGACATTTGTTTTGCCCGCTTCACGCAGTCCAACTCGCTGAAAGCACACAAGCTAATCCATCAAGTTGGCGACAAACCAGTGTACCAGTGCGAGCTCTGCCCTACTACCTGCGGTCGTAAGACCGACTTGCGCATTCACGTGCAGAAGCTGCACACGGCAGAAAAACCGATCACGTGCAAACGGTGTGATAGCTCATTCGCCGACCGGTACTCCTACAAAATGCACGTCAAAACACACGAAGGCGAACGTTGCTTTAAGTGTGAGTTCTGCCCGTACGCTTCGATTTCGGTACGCCATTTGGAATCCCATTTGCTTTTGCATACCGACCAAAAGCCGTTCCAATGCAAGGAGTGCAGCCACTGCTTCCGACAGAAGCAGCTACTCAAACGGCATATTAACTTCTACCACAACCCGGACTACGTTGCGCCGGCGCCGAAAATGAAGACGCACGTCTGTCCGAACTGCCCTCGGTCTTTCCGGCACCGGGGGAACCTAATACGCCACATGGCATTGCACGACCCCGAGTCTCAGCTGCATGAGGAGCAGGCGGCATTGCGTGAGGGTCGCCAGAAGAAGGTGCAAATAACGGTCGAAGGGATGACGGATGATGAGGACTCCCAGGAAATATTCGGAGCAGGGGATGTTGTCACTGTGCAGGATGACGATGGACAGTTCGTAATGTTGGAGGTGATACAGCTGCAAGAAGGTAGTAGTGCTAGTGGCAATCAGGCTGTTTCCGAGAAGGCTGGCTCAAAGGCtgcgaaaaaaacagatcCAGCTGGCACTAGTTCTGTTGCATCTACGACGGCATTGGAGGCGAGACCTACGAGGGCAGCGAAGGCAAAAGCGCTGCAATTGAAGTTGAATAAGGAGGGAAAAGTAGTGCGAGAAAATGATAATTCGCTGGACGGCGAGGAGGATTTCCATGGCGTAGCTGATGAAGAGATAGAGGACGAGGGCGAAGAGATCGAGATCGATCAGGGCGACGATAGTTCGGCTAGTGAATTCATTCTCTCGACAGAAGACCTAGAAGACACCGAAATGCTCATGTCATCGCTGCAGAGGAGCTCAAGGCGAGAACGCTTTAACCTTAGCAGTATCAACGTAAACCAAGCTGAAATACAGAAAAATATGGACAACTGTTTCGGGTTTTCTgacgatgatgacgaagaaatGCATGAAAAGGCAACTATTACTCTTCTACAATGA
- Protein Sequence
- MKPKSESGSGIKKYLNKSNRQPREIANKATITRTRKGGEEIMPAPIQIAKQEKPDDNDDEDDLMMTATDTVNDAEEEGCYFVDQKGNYYFQATEDAEPVLTAVTNEPSGFSAVDGEGMKIEQNGVSYVLVMDDGGNKSTIVADTNDAGNLVPDEDEIYEFADSDFLVDEPPTSEKRTRGKKETLADAAVHMCNYCNYTTKKMFLLSRHLKTHSEDRPHKCSVCERGFKTMASLQNHVNTHTGTKPHHCKNCDNSFTTSGELVRHIRYKHTHERPHKCTECDYSSVELSKLKRHIRTHTGEKPFQCPHCTYASPDKFKLTRHLRIHTGEKPYSCDICFARFTQSNSLKAHKLIHQVGDKPVYQCELCPTTCGRKTDLRIHVQKLHTAEKPITCKRCDSSFADRYSYKMHVKTHEGERCFKCEFCPYASISVRHLESHLLLHTDQKPFQCKECSHCFRQKQLLKRHINFYHNPDYVAPAPKMKTHVCPNCPRSFRHRGNLIRHMALHDPESQLHEEQAALREGRQKKVQITVEGMTDDEDSQEIFGAGDVVTVQDDDGQFVMLEVIQLQEGSSASGNQAVSEKAGSKAAKKTDPAGTSSVASTTALEARPTRAAKAKALQLKLNKEGKVVRENDNSLDGEEDFHGVADEEIEDEGEEIEIDQGDDSSASEFILSTEDLEDTEMLMSSLQRSSRRERFNLSSINVNQAEIQKNMDNCFGFSDDDDEEMHEKATITLLQ
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -