Basic Information

Insect: Anopheles plumbeus
Gene Symbol: ham
Assembly: GCA_034621735.1
Location: JAOEFI010000004.1:6776694-6822289[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.00031 0.027 15.0 0.1 1 23 348 371 348 371 0.96

2 8 2e-09 1.8e-07 31.3 0.9 1 23 377 399 377 400 0.96

3 8 1.5e-06 0.00013 22.3 1.7 1 23 406 428 406 428 0.95

4 8 1.4e-05 0.0013 19.2 5.9 1 23 434 456 434 456 0.99

5 8 0.0035 0.31 11.6 1.3 2 21 464 483 463 484 0.95

6 8 5.2e-09 4.6e-07 30.0 1.1 1 23 1082 1104 1082 1104 0.99

7 8 1.6e-06 0.00014 22.1 1.6 1 23 1110 1133 1110 1133 0.97

8 8 0.00014 0.012 16.1 6.7 1 23 1139 1161 1139 1161 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.00031	0.027	15.0	0.1	1	23	348	371	348	371	0.96
2	8	2e-09	1.8e-07	31.3	0.9	1	23	377	399	377	400	0.96
3	8	1.5e-06	0.00013	22.3	1.7	1	23	406	428	406	428	0.95
4	8	1.4e-05	0.0013	19.2	5.9	1	23	434	456	434	456	0.99
5	8	0.0035	0.31	11.6	1.3	2	21	464	483	463	484	0.95
6	8	5.2e-09	4.6e-07	30.0	1.1	1	23	1082	1104	1082	1104	0.99
7	8	1.6e-06	0.00014	22.1	1.6	1	23	1110	1133	1110	1133	0.97
8	8	0.00014	0.012	16.1	6.7	1	23	1139	1161	1139	1161	0.99

Sequence Information

Coding Sequence: ATGCTTTCAACAGGCATCAGTGGCGACGAATCGGACGCATCCCGTGGACTGCCCGTCAATCTTGAAGTGCCTCCAGGACTGCAGGTGGTACCGATGAGCAAACATCACGAGCACGGTCCAGCGGAGGTCAGCCTACCGACGACGCTCCACCATCACCTCCTGCCCACGGTGGACGATGTTCGCGAGCGGCTGAAGCTTCACAGTGCACAACAGTTCCTCCAACAGATGGCACGACTTCAGCGGCCACCACCGGATCTGGACGTGCAGACCGGATCCGTGCTGGCGTTGAAGTCCATCCCGAAAGGTACCCAGTATGGCCCGTTCGGAGGGAAGCTACTGCGGGAACCGATGGATCGACGGTACGCATGGGAGGTGATTGACCTCGACCTTCGAGGTTGGTTAGACGCAACATCCGAGCCGACGAACTGGATGAAACACATTCGCAGCACATCTTCCGGTGCGGAAGAGGTGAatgtgcaacattttctcaaAGATGGTCATCTGTGGTACGAAGTGATATGTGATATCAGTCCCGGAAGGGAACTGCTGCTAGGTCCGAAGGTTCCTCTTCATCCCAGGGATGGCCAAGACGAGCGGGGCAGCGAGCGAGGATCCGGCGGTTCCCAGCACAGTGAGAACTACGAGGACGAGTACAATACCTCGAACGAGCTTGACTCTAGTCTCGGCAACAAggagcgccagcagcaccatctccacaacagtagcagcaacagcagcaacagcagctcgTGCAGCACCGGCCGGCAGGAGCACCACCGGGGACGGGGTGGCaaggcgaacggaaacggccaccaccaccagccggacGACAGTGGCAACGGGAGCAGcgatctccagcagcagcagcagcagcagcagcaacagcagcaacagcagcagcagaactcGTCGGACGTcaaggaggaggacgaggacgagcaggGCATCGACGCGCGGTGTGTCGTCTGTGAACGACAGTGTCACGATATTGATCAGCTCGATGAACATCTCGTGATCTCGCACCACTACCCGAAGGACGCCTACAGGTGTGAACTTTGTCCGCGGGCCTACAGCTACAGGCCATCGCTGCTGCGACATCGGGCGATCGTGCACGGCGAACTACGGCGCTTTCCCTGCGAAAATTGCCCCAAGGTTTTCACCGATCCGTCTAACCTTCAGCGTCACATCCGGACGCATCACGTGGGAGCGCGCAGTCACGCGTGTCCGGAGTGCGGCAAAACGTTCGCCACCTCGTCGGGCCTGAAGCAGCACACGCACATCCACTCGTCGGTGAAGCCGTTCCAGTGCGAGGTGTGCTTCAAGTCGTACACCCAGTTCTCGAACCTGTGCCGCCACCGGCGCATGCACGCCGACTGCCAAGTGCAGATCAAGTGCAACAAGTGCGGCGACAGCTTCAGCACCACCACGTCCCTGTCGAAGCACAAGCGCTTCTGCGACTCGACGGCCATCGCGCGGCCGCCGCTCGGTTCgggccatcatcaccatcaccaccaccaccaccatccgtcGCAGCTGCGCCCGCACGAGCTGTACTCGCACCGGCAGCCACCGGGGAACGGTCAGCCAGGGTCCGGCAGTAGCGGTGGGGCAGGTGTAGGAGCGTCCGGAGCAGGACCGCCGACGGGACCGACCGGAGTCGCAGCCATTCATCCCCTGGCGTCCGGCATGGCGACGCCACCGAACCCGTTCCTGATGTTCCCGGGGGCGCACGCCTTCTTCACGCCCGGCTTCCGGCCGTACCCGGGCATGCCGGGAATGTTTCCTCCCACGCCCGGCCAAGCACCCCAGTTCCCGCTGCCCTTCTTCCCGAAACCGCAGGCACCGCTGGGTGGCGTGTCGATGGAGCCGGAGCGCAAGACCCCCTCGCCGCCGTCGCGGGACCATCTGAGCCTGTTCGAGGGCTACGGCCAGCAGTCGATGAAGATTTCGCCCCCGACGGCCGAGGAAGCCACCAACCCGCTGCGACCGTCGCCCGCCCGTCCGATGCCGGTCAACTTCAACTCGacggctgcggctgcggtCGCACTGCTGTCGGGGGGCTCGCCGGGCCCGCTGGCCCACCAAGGGGCGGAACTGCACCAGCATGGCAGctccggcagcaacaacaatcacaTCAAGGAGAACAACAATCACAACGGCACCAGTTCCTACGGCCAGGCGTCCCGACAACGCCGGGCGTCGAGTCGAGCCAGTTCGGTCACCGCGACGAGCACCGGGCCCACCGAGCAGCATGCGCCACTGCTGGTAGATGGTTCCGACGGGGACGAGGATGTGGACGTTGGGTTGTCCGCTTCGATCCGCGTGAAGAACTTTTCGATGTGCTCAAGGGATGCCTCTGGGGATGAAGCGGGATCGAGGGCGAAACCGGGGAAGTCACCGGCGCTGGCCGACCAGGAGAAGCACTCGCTCCGGCGGAGAAGCCGCACGGTTGATGAAGAGGAAACGTCAGAATCGGAAGGGTTCGTTGCCAACGAAGCAAAGAAGatgaaaaaagaagacgatGGTTCCACCGTCACCGAGCAGCCGCTCGATTTGAGTCTTTCGAAGAAGTCGAAGAACGACTGCGAGGATGGCGACGACGAGaaggatgatgacgatggcaacCGGAGCTGCAATCGCAGTCCGACGCCGATCGAAGTGGCCAGTCCCACATCCACCCCGACACCCTCGGTGCCGACGCCCAGTTCCTCGGAGGTTACCACACTCCACCACGATCTGTCTCTACGCACACGGGGCGGGCGGAATCGCAATGGTGCGCTGGCGCCATCCATTTCCCCGAAGGTGCCTACCGCGTCACCCTCCGCGGACGTGTTTGCCCTTCCGAGTCCTTCGCCCTCGCTGTCGCCGCGTCCCTCACCGACACCATCGTCACCGGGAGTGGGCGGTGGCGCGAATGCCGGACTGCTCGGCGTCGGTggtcagcagcatcagcccATTTCCTACCCGAGACCGATCTACCCGCTGCTCCTGGAGGCGATGTATCACCGGCCGGGTGCAATGAGCGCCTTCCAGCGTCCCACGTTCAACTTCCTCGACTCGCTGGAGTCCAATCTCGATCTGCTCAAGCGCAACCGCCACTACATGCCCTCGAAGGCGTTCCACCAGGCCATGATGCCGCCGGGTTTCGGAGTGGGTGCCGGCGGTCCCGGTGGCGGCACCGGAACTCCCGGCGGTCCAGCCGGTGCACCGGGAACCGGGCTCGTCGGCAAGGTGAAGGACCGCTACTCGTGCAAGTACTGCGGGAAGATCTTCCCCCGCTCGGCCAACCTGACGCGCCACCTGCGGACGCACACCGGCGAGCAGCCGTACAAGTGCCGGTACTGCGAGCGGTCCTTCAGCATCTCCAGCAATCTGCAGCGCCACGTGCGCAACATCCACAACAAGGAACGGCCGTTCAAGTGTCACCTGTGCGAGCGCTGCTTTGGCCAGCAGACCAACCTCGACCGGCACCTGAAGAAGCACGACGCGGACGCATCCGGCCTCGGATTCGGGCTGGGCGATTCACCCTCGTCCAACGAAGCCGAACGCGGTGACGATTTGATCTTCGACGAAATCCGATCGTTCATGGGAAAGGTTACCTACACCGGACCGGCGGCTCTACTGGCCGCTACCGCCGGCAACGGGTTGACCGGTGCGGCTCGGGTCGACACAGACGCCGTGGAGAAAGTTGACGAAGAGACGGCCGTTGACTCGGTGGAACTGGGTGAGGACgatgaggaggaagaggacgcGACCAGCTGCGATGGGGAGAGCGATCTGATCAACATCGATTCCGACAAGGACACGATCAACAACAATGACACGATCGAGGTTTCCACCTAA
Protein Sequence: MLSTGISGDESDASRGLPVNLEVPPGLQVVPMSKHHEHGPAEVSLPTTLHHHLLPTVDDVRERLKLHSAQQFLQQMARLQRPPPDLDVQTGSVLALKSIPKGTQYGPFGGKLLREPMDRRYAWEVIDLDLRGWLDATSEPTNWMKHIRSTSSGAEEVNVQHFLKDGHLWYEVICDISPGRELLLGPKVPLHPRDGQDERGSERGSGGSQHSENYEDEYNTSNELDSSLGNKERQQHHLHNSSSNSSNSSSCSTGRQEHHRGRGGKANGNGHHHQPDDSGNGSSDLQQQQQQQQQQQQQQQQNSSDVKEEDEDEQGIDARCVVCERQCHDIDQLDEHLVISHHYPKDAYRCELCPRAYSYRPSLLRHRAIVHGELRRFPCENCPKVFTDPSNLQRHIRTHHVGARSHACPECGKTFATSSGLKQHTHIHSSVKPFQCEVCFKSYTQFSNLCRHRRMHADCQVQIKCNKCGDSFSTTTSLSKHKRFCDSTAIARPPLGSGHHHHHHHHHHPSQLRPHELYSHRQPPGNGQPGSGSSGGAGVGASGAGPPTGPTGVAAIHPLASGMATPPNPFLMFPGAHAFFTPGFRPYPGMPGMFPPTPGQAPQFPLPFFPKPQAPLGGVSMEPERKTPSPPSRDHLSLFEGYGQQSMKISPPTAEEATNPLRPSPARPMPVNFNSTAAAAVALLSGGSPGPLAHQGAELHQHGSSGSNNNHIKENNNHNGTSSYGQASRQRRASSRASSVTATSTGPTEQHAPLLVDGSDGDEDVDVGLSASIRVKNFSMCSRDASGDEAGSRAKPGKSPALADQEKHSLRRRSRTVDEEETSESEGFVANEAKKMKKEDDGSTVTEQPLDLSLSKKSKNDCEDGDDEKDDDDGNRSCNRSPTPIEVASPTSTPTPSVPTPSSSEVTTLHHDLSLRTRGGRNRNGALAPSISPKVPTASPSADVFALPSPSPSLSPRPSPTPSSPGVGGGANAGLLGVGGQQHQPISYPRPIYPLLLEAMYHRPGAMSAFQRPTFNFLDSLESNLDLLKRNRHYMPSKAFHQAMMPPGFGVGAGGPGGGTGTPGGPAGAPGTGLVGKVKDRYSCKYCGKIFPRSANLTRHLRTHTGEQPYKCRYCERSFSISSNLQRHVRNIHNKERPFKCHLCERCFGQQTNLDRHLKKHDADASGLGFGLGDSPSSNEAERGDDLIFDEIRSFMGKVTYTGPAALLAATAGNGLTGAARVDTDAVEKVDEETAVDSVELGEDDEEEEDATSCDGESDLINIDSDKDTINNNDTIEVST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -