Aplu010277.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles plumbeus
Gene Symbol
-
Assembly
GCA_034621735.1
Location
JAOEFI010000007.1:20297761-20300890[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 0.0028 0.25 12.0 6.1 1 23 228 250 228 250 0.97
2 14 3.4e-06 0.0003 21.2 0.1 1 23 274 296 274 296 0.98
3 14 3.6e-07 3.2e-05 24.2 0.7 1 23 302 324 302 324 0.98
4 14 1.5e-06 0.00013 22.3 3.5 1 23 330 352 330 352 0.98
5 14 0.00017 0.015 15.8 0.7 1 19 358 376 358 379 0.95
6 14 1.3e-05 0.0011 19.4 0.8 1 23 385 407 385 407 0.98
7 14 1.4e-07 1.2e-05 25.5 1.1 1 23 416 438 416 438 0.99
8 14 3.5e-07 3.1e-05 24.3 0.6 1 23 444 466 444 466 0.99
9 14 0.013 1.1 9.9 0.3 2 19 474 491 473 492 0.94
10 14 0.00019 0.017 15.6 1.1 1 23 588 610 588 610 0.98
11 14 1e-06 9.3e-05 22.7 1.0 1 23 661 683 661 683 0.97
12 14 1.4e-06 0.00012 22.4 2.9 1 23 689 711 689 711 0.99
13 14 8.1e-06 0.00072 20.0 3.5 1 23 719 741 719 741 0.99
14 14 2.1e-09 1.8e-07 31.3 2.4 1 23 747 769 747 769 0.99

Sequence Information

Coding Sequence
ATGGCAGAGGATTTATCgatcaataaaaataagatTTTTGCACAAAGATACGGAAATAGTAATAACGACATTTGTCgattgtgtttgaaaaatgagcCTCACATGGAACCATTGTTTTATTCCAACCAGTTTCCCAACATTTTGCTCACGAAGAAAATATACGATTGTACTTCAATACAGATCATTTACGAGGGGAATCTGCCGATGTTTGTCTGCAAACTGTGCGCCAACAAGCTGGACGAATATTTGCGCTTCCGGGAGAGGTGCATTGCGAATGACGAATTTCTACGGAACGCCTTGGCCGCATTCGATATGGGTAAGGCGGCCAACTGTTCCGGCCcgataaaaaaggaacctGATGgtacgccaccaccaccgacaaaGCTTGCCCAGTGTCTCGGTGTGATGCCGATGGAGCTAAACTGTGCCCTagtggtggcggcgacggctgcGGCAACCGGCCACCAACAGGCGAAGAGGGAACCACCTGATATTGGCGACGAGGAGGAAGTGTCGTCGAATGTGCGGATGTATGAACACCGATCACGGACAGCGTCGCCAGATCGTAGTTGTGGAATGGCTGAAGACTTTACTGTGCGAAAGATGCATGATGGTATATATCGGAGCGCCACAATCGATGAACTCGATGCCCATATCGACGACGACCGGCATGAAAACCCACATGTTTGCGAAGTTTGTTCGAAGTCATTCAAAATCCGCCACCAACTTCTTGTGCATAGGCACACACACGTTGACAATCATGAGATACCGGTCAGCCTTCTGAACGGTTCGGGTGGCGCTGGAGGCGGCAAACAGTCGTACGACTGTCCAAAGTGCGCCAAAGCGTTCGTCAACAAGGGCAACCTTCTCAATCACCTCGAGACGCACACAAACGAGAAGAGCTACGCGTGCGAAATCTGCTCGAAAACGTTCAAGTACAATGTGCAGCTGCGGTTGCATATGCGCATCCACACCGGGGAACGGCCGCACAAGTGCGAAGTCTGCAATCGTGGTTTTTCGCAGCTATCCAACTTGAGGTCCCACCGGAAAACTCACTCCAAAGTCAAACCTTATAAGTGCCATTTATGTCTAAAGAGTTTCACCATGCTAGACAACCTAACGGCTCACAGTGCCAAGTGCTTGAAGGACAAGTTCCGATGCACACTCTGCTCAAAGTCGTTCGCCAAGGAGGGCAACCTCCTGTCGCACCTGCAGTCGCATAGTGAAGGTGTTGTGGAGAAGATGTTTAAGTGCGAGATGTGTCCCAAGAGCTTCAAGAACAAGGAAGACTGGAAGCGACATGTTCGAGTGCACACCGGCGAAAAGCCGTACACTTGCGACATATGCTCCAAAGGGTTCGCCCAGAAAGCGAATCTATTGTCGCACCAGAAGACACATCTCAAACCAAACGTCATTATCAAATGTGACCGCTGCGAACGCACGTTCCGGTCGCAGAAAGTGCtcgaaatacattttcccaaGTGTGGCGGACAGTCTGTGACTGTCGGTAGCGTAGGAGATGTCTCCACCCCTGTAACACCACGCTCGGAATCGACACCAGGTTCGCCGAGCCCGGGGATATCCGTGACATCCCCCGCAGCGGCCACCGTCACGCCATCGCTCTCGGAAGCTCTTTCCGATCTGCTCCGGTACGAGATTGCTCTCAGGGCACCGCTGGAGCTGCAACAAATGCTTCTGGGGCATATGGAtcgaaaaaaaccacacgtgACAGGCGGCGGTGGCAAGGCCGCTGGGCGCCGTTACCGGTGTGACGTTTGTTTCAAGGGGTACTCCCAGTACCCTTCGTTAATTAAACACCGAAAGCTGCACTTCAAGGTACCGCCATTGGTGAAGGTTCTAGCCGCCAAGACGAAACAGACGCCGGAACACCGCGCCGATGGCGACAGCGACGGTGGGACTGACGAGGCGCCAGGGCAGATGGCTTCAACACCTGAGCTCCCGTGCGACCCCGAGCGACCATACAGCTGTGATATTTGTGGTAAGAACTTTAAATACAATCGTAACCTGAAGGTTCACGCCAAGCTGCACGTCAGAGCGAACCGTTTTAAGTGTGACAAGTGTACCACCACCTTTGCACAGGCGGAAGATTTGAAACACCATCTGCGCACCCACCCGATCGCTGCCGAGAGGATCTTCAGATGCGAGTACTGCTCCaaccggttccgttcgaacgAGGACCTGAAGCGACACCGGCGATCTCACACCGGCGAGCGGCCTTTCCGTTGCACGCACTGTCCGAAGGCGTTCACGCAGCAGTCGAACCTGCGGGCCCACATGAGGATCCACGAACGACAGTCGACATGCAGAGCGCAACAGCGAGAGGATCGgatccttccggtggtggcaTGGGCACTGGAACGGGAAAGGGAATTGTGTTTCCAGGAATTCCTGGAGAACCGGGGCGAGAACCACAGAGATGcgtaa
Protein Sequence
MAEDLSINKNKIFAQRYGNSNNDICRLCLKNEPHMEPLFYSNQFPNILLTKKIYDCTSIQIIYEGNLPMFVCKLCANKLDEYLRFRERCIANDEFLRNALAAFDMGKAANCSGPIKKEPDGTPPPPTKLAQCLGVMPMELNCALVVAATAAATGHQQAKREPPDIGDEEEVSSNVRMYEHRSRTASPDRSCGMAEDFTVRKMHDGIYRSATIDELDAHIDDDRHENPHVCEVCSKSFKIRHQLLVHRHTHVDNHEIPVSLLNGSGGAGGGKQSYDCPKCAKAFVNKGNLLNHLETHTNEKSYACEICSKTFKYNVQLRLHMRIHTGERPHKCEVCNRGFSQLSNLRSHRKTHSKVKPYKCHLCLKSFTMLDNLTAHSAKCLKDKFRCTLCSKSFAKEGNLLSHLQSHSEGVVEKMFKCEMCPKSFKNKEDWKRHVRVHTGEKPYTCDICSKGFAQKANLLSHQKTHLKPNVIIKCDRCERTFRSQKVLEIHFPKCGGQSVTVGSVGDVSTPVTPRSESTPGSPSPGISVTSPAAATVTPSLSEALSDLLRYEIALRAPLELQQMLLGHMDRKKPHVTGGGGKAAGRRYRCDVCFKGYSQYPSLIKHRKLHFKVPPLVKVLAAKTKQTPEHRADGDSDGGTDEAPGQMASTPELPCDPERPYSCDICGKNFKYNRNLKVHAKLHVRANRFKCDKCTTTFAQAEDLKHHLRTHPIAAERIFRCEYCSNRFRSNEDLKRHRRSHTGERPFRCTHCPKAFTQQSNLRAHMRIHERQSTCRAQQREDRILPVVAWALERERELCFQEFLENRGENHRDA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-