Basic Information

Insect: Anopheles minimus
Gene Symbol: ZNF219
Assembly: GCA_000349025.1
Location: KB663644.1:5597894-5675376[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.29 16 5.7 0.5 3 23 365 387 363 387 0.91

2 15 0.0043 0.25 11.5 1.9 2 21 584 603 583 604 0.95

3 15 0.032 1.8 8.7 0.4 1 23 624 647 624 647 0.95

4 15 0.29 16 5.7 4.5 1 23 652 676 652 676 0.93

5 15 0.37 21 5.4 0.1 2 23 693 715 692 715 0.91

6 15 0.0011 0.064 13.3 0.1 1 21 720 740 720 741 0.96

7 15 1.2 66 3.8 0.2 2 17 993 1008 992 1014 0.81

8 15 0.0036 0.21 11.7 1.3 2 23 1042 1062 1041 1062 0.93

9 15 1.6e-06 9.3e-05 22.2 1.2 1 23 1068 1091 1068 1092 0.94

10 15 0.055 3.1 8.0 1.5 3 23 1125 1145 1124 1145 0.94

11 15 5 2.8e+02 1.8 1.3 1 23 1154 1178 1154 1178 0.95

12 15 0.61 35 4.7 0.1 1 23 1184 1209 1184 1209 0.88

13 15 0.0017 0.094 12.8 1.8 1 23 1216 1238 1216 1238 0.98

14 15 0.00045 0.025 14.6 2.2 1 22 1244 1265 1244 1269 0.92

15 15 6.6 3.7e+02 1.4 2.8 1 10 1275 1289 1275 1303 0.59

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.29	16	5.7	0.5	3	23	365	387	363	387	0.91
2	15	0.0043	0.25	11.5	1.9	2	21	584	603	583	604	0.95
3	15	0.032	1.8	8.7	0.4	1	23	624	647	624	647	0.95
4	15	0.29	16	5.7	4.5	1	23	652	676	652	676	0.93
5	15	0.37	21	5.4	0.1	2	23	693	715	692	715	0.91
6	15	0.0011	0.064	13.3	0.1	1	21	720	740	720	741	0.96
7	15	1.2	66	3.8	0.2	2	17	993	1008	992	1014	0.81
8	15	0.0036	0.21	11.7	1.3	2	23	1042	1062	1041	1062	0.93
9	15	1.6e-06	9.3e-05	22.2	1.2	1	23	1068	1091	1068	1092	0.94
10	15	0.055	3.1	8.0	1.5	3	23	1125	1145	1124	1145	0.94
11	15	5	2.8e+02	1.8	1.3	1	23	1154	1178	1154	1178	0.95
12	15	0.61	35	4.7	0.1	1	23	1184	1209	1184	1209	0.88
13	15	0.0017	0.094	12.8	1.8	1	23	1216	1238	1216	1238	0.98
14	15	0.00045	0.025	14.6	2.2	1	22	1244	1265	1244	1269	0.92
15	15	6.6	3.7e+02	1.4	2.8	1	10	1275	1289	1275	1303	0.59

Sequence Information

Coding Sequence: ATGCTCAACGAAGAGGACACCGAGCTGGATGACACTCATCTCTGCATTAAGTGTGGCAGTACCGTGGAGGGAATTGAAAATTACATCAAGCACCGTAAGGTAAATTGCACACAGCCGGTCAAATCTTCAGGTGGCACCGATGGTGAGCCCGGTACCGGAGCGATTGGCAATGCCGATCAACCGACCGTAGCACTGCGCGTTGAAACGGCAACAGCGACGGAACCGGCGCCCTATGGGACGTTCGACTTTACCGAAACAATCAAGGAACCGGAGCACCATAAGAAAGTGCCGAGCTATGACTATCATAACTACGAGCTGGagcctcatcatcatcatcatcatcatactgACCCGGAGCATCACCGGACCGATGGTTCGAAAGCGCCCGACTATAAGAACGAAGTGAATTACGAGTACGAGTTGGGAGCGGATCTGTTCTTTTCGTCGCTTGAGCTGCAGAGCAGTAGCAAGCAGAAGACAGCAGCCAACACCCTGCCCAATGCTTCCCAGCACAGCGGTGCCGGGGTGATCGGTGGTGGTTGCAGTCCTGCAACAAAGATAGCACTGTCGCAGTCTAGACCGAAGACCCGCAAATTTACCACATCCCTCGTCACGCAGCTCGAACcagatcagcagcagcagcagcagcaacagcaccatccgCTACCGGACGACTGGCTGGCGACACCGAACGAGTCCGATAAGCTTATGAAAGCTGTCAGCGATATCAGTGGCCACAAAAAGGTGGAACTGTATCCGATATTCCATCAGGAATCTCCCGACCCGTCGGACGACGACAGCGAGGACGAAGATGACTATAATGCACCACCGCGCACCCATACCGGTGGCAAGTGGAAACCGGAAAATCGTCCATCACCGAACGTACTGCGCAGTACGTCCCACTGGCGCCACTGGCCACCGGAGTCCCCGCTGGACAAATCCATCGAACAGGACGAGGAAGACGATAGCTTCAAGAGCTTCTCGCCGCCGCCCGGCCACACCAAGGGCAAGTGGGTGCCCGGTTCCAAGATTGCGCGGCTCGAGTACAAACCAACCCACGAGCCGGTGAAAAGCTACGAGGACAATTACTGGTGCAGTATTTGCAACCGTCGGCTGGCCTCACGGTTTGTGTACGAGCGACATCTTAAATCAAATCTGCACCTTAAACGGGCCCAGGAGGAATTCGAGCTAGAACGTGCCATCAAGCCGCCGCTCTACGCTAATGAACTGTCGAAGCAGCTAACGGACGCACCGTACACCGGAGGTTCCGCCGAGCGCCCGGCTGAGCAAGTGACCACCACGGGTCAATTAACGAAGTTACCGGTAAAGGTAAAACGCAAACGCAAATGCTACTACACCAAGTGTGTCGTTTGTCAGACGCGTCTGCCGACGCATCTGCTCGGGAAACACTTGATATCCCGTTACCATTACCGTCGGATGTTGAACCACCCGGAGCAATGCTTTGACGTGGTGCTGAAAAATATGCACCGCATCGTGCTACAGTCCCCGTTCCAGTGTCAACCGTGCCGGTTTTACGCAAATAATGAGGTTTACTTTATGGAGCACTGGCGTTCACCGGAGCACGAGGAACGGGTTGCGTCGAGCGGAAAGTTTTGGTGCAGTTTCTGCAAGTTCGAATGTGAGGGAAACTTCCAGATGACCGAACACCTGCTCGGTGCGAATCATCGCGAAGTGATCGCTGTCATCAATCGCTCGGTACCGATCATCATCCGCAAGATCACACGCATCCGTTGTAATTCCTGCGAGCAGGAGTTCCGATACAACGCCGAATTGCGGCACCATCAGCGACACTGCACGGCGGTCAGCGACGAAGCAATGGAGGAGGTGCGGGCCAAGGTGCAGAACACCTTCACCTGCGAGCTATGCAGTGTTACCTTCCCGAACAGGATACGATTGCTCCAGCATGGTCAGAAACTGCACCGGCTGGCGAACTATTACTGCTCCATTTGCGAGTGTTCGTTCGAAACGGCCCACGAGTCGATGCAACATCGTCGTACCTCGAGGCACAAGATTATGTCGGCAAGAAAGAATCGAAAATCGAACCTGGTTCCGAAGACGTGCCCCGTGTGTAAGGAAAAATTACCGGATGTACTGGAGCTGAAGCAACACATAGCAGACAATCATCCGGATGTGAAGTATAGCTGTCCTCAGTGTGGCGAATGTTTCGTCCTAGCGCAAGAACTCGGTAGACACGTACGTGacaaaaattgtacatttttcaattcctcCACCGCGCTGGAGACACCGTCAACGTCCTCGGCGTTCTTTGTGCCGTACTCGACAACGGAAGTGCTTTCGATTCCGGCATCGTCCATATCCACGTCGACGCCGCCgccgacaacgacgacgacacaTCAGCTCGCTGGTGCACTCCCGACGATAGTCCCACAGGCGGAAACTTCACCATTGTCATCATCAGCAACCCGGCCGCATCTTTCGGGCACAAATTCAATTATCTCAAATGATtcaattaaagtaaatatGAATGATCGTAAACTAGGCAAGGAGACACATCTGTATTCTTCCACGGTGGCACCGTTCCTGGAGACGTCCACGGACCGGGAATCGGATGCCGAACCCGAATCGTCCACGGATGATGCGGATGGGCCCAAGCAACCGGGCCCAGCTGATCAGCCCCGAAAAGTTGAtatgatggaaaattattcaccCGCCAACGCGACCCCACCGCCGGTGACCACATCGACCTATCGGATTAAATTGGAATCGTTCAGTTCGGCAGTTTCGGGCGGATCGGCCACGGTCCACCAACCGGACGCCCCAACACAATCGCCGGTGGTATCAAATTCGGATTGCGATAATATTGTTGCCGCACGGAGCCCGCAAGCGTCAGCAGAAATCTTTTTCGCCATGGCTAATAATGCGTCCGAAAATAATACTGTTTACGTTGATGAAATTGTTGGCACCATCGGCGAGGACGGTTCGGTCGTTTGCTGGCAGTGTAAAATATGCCCATTCAGaaCCTCATCGCAAGCCGAATTTCTGTTTCACGAAATTTTGCACTCATCAAAGTTGGATGACAAAGCAAAGTCATCCCCATCGGGGTCGTCGTCTACGTCGGGGAAACGTCGGTGTCCCAAAATCACCTGCCCGTTGTGTGGGAAAGCATTCTCCAAGGCGTCCCTCCGTTGTCACCTGCGCCAACACACCGACGAACGGTTGTTCCCCTGCCCGCACTGTCCGATGGCATTTACGCGCAAGGCCAATCTCAAAAATCACATTGATAACattcaccaccaacaacaacagcagcggAAGCATAACATTGGAGGTATGGGAGAGAGTGAAGGAATGCGTTCCACTGACGAAGCAGGACCATCCCGCCGGGCCATCTGTACTAGTTGCGGCAAATCGTTCGCCAATCGTCACATCATGCTGCAGCATAGCCGCGTCCATCAGGATCAACGATCCGTCAAGGAGTTTTCCTGCCAGCACGAAGGATGTCACTATCTGGCCCGTTCCGCAGCCGATGCCCGGCGCCATTTGCTGTCACACTCGAGCGAACGAAACTTTGCCTGCGGTGATGTCGGCTGCGAGTACCGGGGGAAATCTCTGGCCCAGTTGCGTAGGCATGCCCTTCTTCGCCATGAGGATATGGAGAAGAAGCACAAATGTGACCAGTGTGACTTTGCAACGCGCATTCCTGGACACCTTCGACGTCATCTGCTAGTGCACTCCGGTAGCAAACCATACGCCTGTCCGCACTGTGATTATTCCTGTAATAATATTGAAAATCTTCGAAAACATGTCATTACCACTTCGAAACATAAAGGGAAATTTTTGTATGAATGTAAAATCTGCCCTAAGGATGGTACCACGTATGGGAGTAATTTCCAGAAGGAGTTTAAAGAGCATAtgcaaaattatcataaattatccCCGGATGAAGTAAAAGCTGCATTAATCATTTAG
Protein Sequence: MLNEEDTELDDTHLCIKCGSTVEGIENYIKHRKVNCTQPVKSSGGTDGEPGTGAIGNADQPTVALRVETATATEPAPYGTFDFTETIKEPEHHKKVPSYDYHNYELEPHHHHHHHTDPEHHRTDGSKAPDYKNEVNYEYELGADLFFSSLELQSSSKQKTAANTLPNASQHSGAGVIGGGCSPATKIALSQSRPKTRKFTTSLVTQLEPDQQQQQQQQHHPLPDDWLATPNESDKLMKAVSDISGHKKVELYPIFHQESPDPSDDDSEDEDDYNAPPRTHTGGKWKPENRPSPNVLRSTSHWRHWPPESPLDKSIEQDEEDDSFKSFSPPPGHTKGKWVPGSKIARLEYKPTHEPVKSYEDNYWCSICNRRLASRFVYERHLKSNLHLKRAQEEFELERAIKPPLYANELSKQLTDAPYTGGSAERPAEQVTTTGQLTKLPVKVKRKRKCYYTKCVVCQTRLPTHLLGKHLISRYHYRRMLNHPEQCFDVVLKNMHRIVLQSPFQCQPCRFYANNEVYFMEHWRSPEHEERVASSGKFWCSFCKFECEGNFQMTEHLLGANHREVIAVINRSVPIIIRKITRIRCNSCEQEFRYNAELRHHQRHCTAVSDEAMEEVRAKVQNTFTCELCSVTFPNRIRLLQHGQKLHRLANYYCSICECSFETAHESMQHRRTSRHKIMSARKNRKSNLVPKTCPVCKEKLPDVLELKQHIADNHPDVKYSCPQCGECFVLAQELGRHVRDKNCTFFNSSTALETPSTSSAFFVPYSTTEVLSIPASSISTSTPPPTTTTTHQLAGALPTIVPQAETSPLSSSATRPHLSGTNSIISNDSIKVNMNDRKLGKETHLYSSTVAPFLETSTDRESDAEPESSTDDADGPKQPGPADQPRKVDMMENYSPANATPPPVTTSTYRIKLESFSSAVSGGSATVHQPDAPTQSPVVSNSDCDNIVAARSPQASAEIFFAMANNASENNTVYVDEIVGTIGEDGSVVCWQCKICPFRTSSQAEFLFHEILHSSKLDDKAKSSPSGSSSTSGKRRCPKITCPLCGKAFSKASLRCHLRQHTDERLFPCPHCPMAFTRKANLKNHIDNIHHQQQQQRKHNIGGMGESEGMRSTDEAGPSRRAICTSCGKSFANRHIMLQHSRVHQDQRSVKEFSCQHEGCHYLARSAADARRHLLSHSSERNFACGDVGCEYRGKSLAQLRRHALLRHEDMEKKHKCDQCDFATRIPGHLRRHLLVHSGSKPYACPHCDYSCNNIENLRKHVITTSKHKGKFLYECKICPKDGTTYGSNFQKEFKEHMQNYHKLSPDEVKAALII

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00104046;
90% Identity: -
80% Identity: -