Amin003965.1
Basic Information
- Insect
- Anopheles minimus
- Gene Symbol
- topi
- Assembly
- GCA_000349025.1
- Location
- KB663644.1:137825-139595[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.00015 0.0085 16.1 1.3 3 23 44 65 42 65 0.97 2 11 0.0064 0.36 10.9 0.1 2 19 95 112 94 115 0.92 3 11 0.16 9.2 6.5 0.3 3 23 152 172 151 172 0.93 4 11 0.6 34 4.7 0.1 1 20 178 197 178 199 0.88 5 11 0.5 28 5.0 1.1 1 23 218 241 218 242 0.94 6 11 0.012 0.68 10.1 0.9 2 23 264 286 263 286 0.95 7 11 1e-06 5.8e-05 22.9 3.2 1 23 321 343 321 343 0.95 8 11 0.0031 0.17 11.9 1.4 1 23 349 374 349 374 0.97 9 11 0.097 5.5 7.2 1.7 1 23 380 402 380 402 0.85 10 11 1.5e-05 0.00085 19.2 1.3 1 23 408 430 408 430 0.96 11 11 4.1e-05 0.0023 17.8 2.9 1 23 436 459 436 459 0.97
Sequence Information
- Coding Sequence
- ATGGAGGCGAAAATTGGAGTTGACGCCATTACAAAAGCGCTCGCGCAAAATACTCTGCAATGGCAAAACATTCTGCAACAATCTAATCCGGAACGCAAAGTGAAAGCGTCGAGCAGGAAACAGTTCGGTTGCGATTACTGCAATCGTAAATTCGTTTACTTGACCGGGCTGCGGCGTCACGTGAAAAAGTTTCATCCCGACAAGATACCCTTGGTCCCAGCGGAACAGACGGTAGTGAGCGCTCCGTCCGATATGCACCCAAAAACGGTTGACGTCGTgctgaaatgtaaaaattgcGGACAAATCTTTCCCGATGTCAAGAGCTTCGAAGCTCATTCCTTGCGCTACAACTGGGAGCAGTTGCTCATAGAGGTATCGTTGGATACGAACGAAAATGGAATGTTGCTGTTTGCGGGACAAATATCGATCGTAGTGATCCATGCAGCGGTGGCATGCGAATTTTGCGACGCATTGTTCTCTGACTATGCGTCACTGTTCTATCATGAGGCGCATCACACGCCAGCCTCCGGCTACGCTTGCACATTCTGTAAGCTGAACTTTCCCAACCTGCAAGCAGTGCTGGATCATCGTGCGCAGTGTTATGAATGCATCAATTTTCGAACAACGCGCCTGTTGAACGTTTGCATTCTGTACAGTTGCAACAGTTGCATGGCTACGTTTGCAACCCTGCCCGAATTGTACGAACACCGCTACAGCAATCATCACTACTTTCCACGCCGGAACGTTGCACTATCGAAGCAGGATGTTCAATTGGACGGTTTGTGGCTTTGCTGCGAAATTTGTGGATTTACTATCGATAACATTTACGAACTGTTTAATCATCGCAACAAGGTCCATTCCGTTGCCGGTATCGGTGAACGTGGTGTGACGGAGAAACCGGCCTCCACCCAACGGGCGGTCAAACGGGCCAATAAGGTGGAATCGGACCACTGTCGGCAGTTCCTGTGCGACAAGTGTGGCAAAACCTACACCCAGTCGAGCCACCTTTGGCAGCATCTGCGCTTCCACAACGGGATAAGACCGTTCGTCTGCACGGTGCAGGGTTGCACCCGCCGCTTTACGATACGGCCCGATCTGAACGATCACGTGCGGAAGTGTCACACCGGAGAGCGGCCATACGAGTGTGATGTGTGCCACAAGCGCTTCCTTACCGGTTCCGTGTATTATCAGCACCGGTTGATCCATCGGAATGAGCGGCGCCACGCGTGCAACGACTGTGACAGCCGTTTCTACCGGGCAGATGCACTGAAGAACCATCGGCGGATTCACACGGGCGAGAAACCATACGCCTGTACGCATTGTGATCGAAAGTTCCGGCAGCGCGGAGATCGGGAGAAGCATGTACGCGTGAAGCACATGAAATAtcgttga
- Protein Sequence
- MEAKIGVDAITKALAQNTLQWQNILQQSNPERKVKASSRKQFGCDYCNRKFVYLTGLRRHVKKFHPDKIPLVPAEQTVVSAPSDMHPKTVDVVLKCKNCGQIFPDVKSFEAHSLRYNWEQLLIEVSLDTNENGMLLFAGQISIVVIHAAVACEFCDALFSDYASLFYHEAHHTPASGYACTFCKLNFPNLQAVLDHRAQCYECINFRTTRLLNVCILYSCNSCMATFATLPELYEHRYSNHHYFPRRNVALSKQDVQLDGLWLCCEICGFTIDNIYELFNHRNKVHSVAGIGERGVTEKPASTQRAVKRANKVESDHCRQFLCDKCGKTYTQSSHLWQHLRFHNGIRPFVCTVQGCTRRFTIRPDLNDHVRKCHTGERPYECDVCHKRFLTGSVYYQHRLIHRNERRHACNDCDSRFYRADALKNHRRIHTGEKPYACTHCDRKFRQRGDREKHVRVKHMKYR
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -