Basic Information

Insect: Anopheles minimus
Gene Symbol: L
Assembly: GCA_000349025.1
Location: KB663943.1:5097176-5146674[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.00042 0.024 14.7 3.6 1 23 232 254 232 254 0.97

2 18 0.63 35 4.7 5.7 1 23 260 282 260 282 0.98

3 18 5.2e-06 0.00029 20.7 3.7 1 23 288 310 288 310 0.99

4 18 1.6e-05 0.00089 19.1 0.3 1 23 316 338 316 338 0.98

5 18 0.97 55 4.1 0.2 2 23 438 461 437 461 0.90

6 18 0.084 4.8 7.4 0.3 2 23 505 527 504 527 0.96

7 18 0.22 12 6.1 0.2 1 23 848 870 848 870 0.95

8 18 7.4 4.2e+02 1.3 0.5 1 23 917 939 917 939 0.90

9 18 0.00034 0.019 14.9 0.2 1 23 987 1010 987 1010 0.93

10 18 0.0007 0.039 14.0 0.8 1 23 1017 1040 1017 1040 0.98

11 18 0.0036 0.21 11.7 1.6 1 23 1072 1094 1072 1095 0.96

12 18 0.44 25 5.1 0.2 1 23 1393 1417 1393 1417 0.91

13 18 0.00063 0.035 14.1 0.2 2 23 1426 1448 1425 1448 0.96

14 18 0.01 0.59 10.3 0.1 1 23 1455 1477 1455 1477 0.97

15 18 0.33 19 5.5 2.1 2 23 1485 1506 1485 1506 0.96

16 18 0.0024 0.13 12.3 0.9 1 23 1695 1717 1695 1717 0.96

17 18 0.009 0.51 10.5 0.0 1 20 1727 1746 1727 1750 0.94

18 18 0.038 2.2 8.5 0.3 1 23 1758 1780 1758 1780 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.00042	0.024	14.7	3.6	1	23	232	254	232	254	0.97
2	18	0.63	35	4.7	5.7	1	23	260	282	260	282	0.98
3	18	5.2e-06	0.00029	20.7	3.7	1	23	288	310	288	310	0.99
4	18	1.6e-05	0.00089	19.1	0.3	1	23	316	338	316	338	0.98
5	18	0.97	55	4.1	0.2	2	23	438	461	437	461	0.90
6	18	0.084	4.8	7.4	0.3	2	23	505	527	504	527	0.96
7	18	0.22	12	6.1	0.2	1	23	848	870	848	870	0.95
8	18	7.4	4.2e+02	1.3	0.5	1	23	917	939	917	939	0.90
9	18	0.00034	0.019	14.9	0.2	1	23	987	1010	987	1010	0.93
10	18	0.0007	0.039	14.0	0.8	1	23	1017	1040	1017	1040	0.98
11	18	0.0036	0.21	11.7	1.6	1	23	1072	1094	1072	1095	0.96
12	18	0.44	25	5.1	0.2	1	23	1393	1417	1393	1417	0.91
13	18	0.00063	0.035	14.1	0.2	2	23	1426	1448	1425	1448	0.96
14	18	0.01	0.59	10.3	0.1	1	23	1455	1477	1455	1477	0.97
15	18	0.33	19	5.5	2.1	2	23	1485	1506	1485	1506	0.96
16	18	0.0024	0.13	12.3	0.9	1	23	1695	1717	1695	1717	0.96
17	18	0.009	0.51	10.5	0.0	1	20	1727	1746	1727	1750	0.94
18	18	0.038	2.2	8.5	0.3	1	23	1758	1780	1758	1780	0.95

Sequence Information

Coding Sequence: ATGGCCAATGGTATAGTGTGGTGCATTGActggttgggttgggttgcGTTCGTGCAAGCTGAATCGGGTCAGAATAATCCCTCCGATAACGCATCCGTACGGTCAGGTGATTCTGTGGAGCGACCGTTGGAAATGGATGATGAGGAAGATAAAAACGATAATGAGGAAATCGATGATGAGGCTGATGAgaatgatgttgatgatgtggatgacgacgatgatgatgaaatagATGACGAATTGCTcgaggacgacgacgatgaggaagGTGATCATGTGCGTCTGGATGGAACGGATGCTCGGGATGTTGATGATGAGTTCACATCGGACAGCTTTTGCTCTGAGCTTTACTCGTCACACACATCATCCAGCTTTTCACCCTCCATTTCGGACGGTATGACAACGCCTAATTCGATCACAAACGATACCAACGATGGTTCGATGGTTGGATTAGGATCCACCGATGAGAAACCGTTCCGGCAGGGTGGTAATCATCACATTCATCcccggcatcatcatcacgctCATCATCGGCGTACGGCAGGAACGGGCGGTGGACATCCATCCTCGGCGAAGGAGGGTGCCAAATCGTCCTTAAAACATCATCAGctgaataataataacagtAGCAGTCACAatcacaataataataacaacaaccatGGCAGTAACAGCAAGGGCTTGAACAGCACCTACCACTGTCAGTTCTGCGAGAAGACATTCCCAAGGCTCGGCTATCTCAAGAAGCACGAACAGAGCCATACGGAGCACATGCCATTCAAATGTGAATACTGTGCCCGACTGTTCAAACACAAACGCTCCCGCGATCGTCACACGAAGTTACATACGGGCGATCGACGCTATCGTTGCCTGCATTGTGAAGCCGCATTCTCCCGAAGTGATCATCTGAAGATCCACATGAAGACGCACGATAACCAGAAACCGTTTCAATGTACGATCTGCAATCGCGGTTACAACACGGCGGCCGCTCTTACCAGCCATATGCAGAACCACAAGAAGCAGCTTGCACTCACCGGAAGTCCTAACCTTACGTACAGTCCCCGATCGACGACTAGCTCTATGTCCAGTGGGGGCGGTGGAGGAAGTGGTGGTAAGCGGGGAGCAAAGTTCTCACCCTATGCAAACGAtccgctgctgctgatgagCCGTGGCAGTTCCAAATTGTCGTCCACACTCGCGAAAGCCTCTTCCGGGAATGTCTCCAGCAATCGTACTCCAACGCCGGGAAGTACTGGTGCGGGAAGTGCTTCGGGTGGTCCGGTAAGTGGAGGTGCTCATGGGGATTTACTATCCTGCCCGTACTGCACGCGGACAGATTTCAGCACGCTAGAGCAACTCGGACTTCACGTACAGTCTATGCACGGCCATGGAGCACTGGGACTGTTGGGAGCGGACACATCAATGCCCTACTTCACGCCGGGTGGTCGGCGTGCAGTAACACCGGACGGGAACTCACTTTCCCTCGGTGGTCTCGGCCCTTATCCACCGATCACATGCGAGTTCTGCACGATGAAGTTCCCAACCGTGCCACTAATGTTTGCTCACCTGAAAACTTCCCATCTGGATCGTCTGGCTGGGGCAGGACTTCAACGCACCTCTCCAAACGGAACTTCCATCAGTAGTCCGTTGGGCGGATCACGTCCACCGAGCGGGTTCCATTCACTAGAACAATTGCACTTCAACAAGAGTCTGCTCGGGAatgcttttccttcgttttacGGTGGAATGGGCGCTGGTTCTTCGACCAACGTGGCTGGCATGTCCGGTGAAAGTATTAAATTGGAACACCGTGCAACGGCCAGTTCGAATGGAcgggatgaaaatggaaacgaatcGAGTGAGGcgggaaggaaacggaaacgaaaagGACACGATGGGGAGAAGGACAGTAACCATGGTAGTGGACGTAAAACAGATAAGCAACAAGAAGATGCTGAAGcaggcgatgatgatgatattgaCGATGGTGATGAGGACCATTTGGAAGAGAATGATGGTAATCGAAGTAGTCCTGTTGACTTGAAAGAACTCAATAGTCACGATCCGGAAAgtgcaaacattaaacaggaaagaaaagatgaaacgGATCAAGCAATTCCGGAAGTTGCATCGGGTTCAACGTCAACCAGGTCGTCTCCTTGCGATTCTCTCGGTTCGATTGTCCATCCAACAAGTCATCCATCGTCCGAACGGAACAGTCCAGCGGAACAGCTCACTCCAACCGATCTCAGCCAGCCGAAGATGAAACGTTTAAAGCTGGAGACACTACTGGAGGATGAGGATGTACCCGAACCCGATAGAAAGCTTCCGACGGTTGGATCCGGGCGGTCTCATACCCGCGAACCTCACAAACAACGTAGTGCTACTACGCGACGAGAGCACGAGCCAAAAGAACCACCACAACATCAGCATATGTCCGTTCCTCAACTACACTCTTCAGGTTCGAATGTCCCACAATCCCAGCAGTTGAATGCGTCCAATTCTACCGCATCTCATCACGTCCATCAGCTTCCTGGAGCTTATCTTTGCAATCAGTGTAATGCCGCATTGCCCGATTTCGAATCTTTCCGCACCCATCTGAAGGCACATCTCGAACAGAGTGCGGCTAATGCAGCGGCGGCTGCTGCGATGCGTCTCACCGGTGATCACAGCGCCACCGGTCCAGCAGGAAGTTCCAACGCTTCCTCCACATCCGGTGCATCTGGTGGATCACTTTCCCTGACCACCTTTCTCTGCCAGCAGTGTGGAGCAACGCTCAGCTGTCAGGCGGAGTACGAGCAGCATACGATCGGCCATTTCTTGGTGATGGCGGTAGAATACCGATGTCAGGCGGCTGGTGGCGGTGGATCGGCTGGGACTTCCTGCACCGGGAAAGCTTCCTTTGGTAAGGTGGAAGATTTACACAAACATCTTTACGAGGGACATATGCAGCTGCTGTACAAGTGTACGGTTTGTGGAGAAACGTTCGATTCGAAGGTTCAGGTGCAGGTCCACTTTGCCGTTAGTCATTCGGTCGAGGTGAAGCTGTACCGGTGTTCGGCCTGTGCAGAAGTTTTCCGCAGTGAACGTGAATTTCGACAACACATCCGGACCCGACATCTAACGGCTGGTGCTGTGCAGTGTATGTTCTGTCGCATGGTTTGCTCGTCCGAGCTCGAGATGCACTTCCATCTTGCATCACACGCCAGAAAGTTCAAATGTCCAGCCTGTCCAGAATCGTTCCACGTAGAGTTCCTGCTAGATCGTCACATTCAGACACACCACAGTCAGAAGGAAACGAGCTCACCGAATCGAAGAGAGTCCACGGTTCCATCTACCGTCCCCTCCACTACTTCTAATCCTTCTTTATCGGTCACAACATCAACGGGAACTTCTGCGTCCACAACGGCCTCCTCATCTGTGGCGGGGTTAGATTACCTACATCTTCATGGACAAATGGCAGCGATGGCAGCGGCCGCTGCTTGGCCTAGTTTGTACCAAACCGCCAACAAGTTCTACAACAACCCGCTCCAAGTGGACACATTGAACCAACTGAAACACCCACAGCATCTTCTGCACGGATTCTACGACACGATGCTTGGAAAGgcacatcaacagcagcaacgttCTTCGTTCCTTCCCGATCCCACAACCGGAGCTGGATCTACACTCGGAAGCAAGAAGAATCCTTTCACCGGTCACTCACCCAACACTAGTGCAACCAATGCACTGCTAGGACTTGGGTACGGTACATCATCATCGGGAAGTTCCGGAACATCGCAACTCCAAAGATCGGCTGGAACTCATACGCTCAATGGTTCAGCCACTGGACTATATTCTCCCGAGGAGGGAACCAATGCAGGATCGGTCGTTCCCGCTGGTAGTGCTAAGCTTTATTCTCCAATTGCCATGATCCAACGGTACGGAGATAATGGAGGTTTACATTCTACTGGTGCAACAGCCGGCGGTAATAACAGTACATCCCGCCCGGGTGTAGAATCACCAACCGGTCAACTGCTGCTGGCATCACACACGTCACTCGGACTACCGGAACATCACCATAGTGAACAACCGGGACGAAAAACGACCCAACAATCAACTTCAAAGTCATCGTCCACGTTGACGACCTCCGGTACGGCACCCCAAATGGCCACAACTTCCAGTGCGGGTAGTTGCTACAGCTGCGGTATCTGTGAGCGATCCGATTTTAGTACGGAAAGTGAAGTCCAAACCCATCGGAAGATTGTCCACAACCTGAAGACGGGCGTTAGTTTGCGTTGTGCGTACTGTAATGGGGATTTCCGGTCGAGAAATGAACTGGAAAATCACATGAAGGTCGCACACAATACGGGTGGTGGCAAGCACAAGTGTTTGATCTGTGACGAAATCTTTCCCTCACCGGCGGTACTTGCTGAGCATAAGCTGTCCCACTGTAAGGTGGGTGCTTCCGGACGCTGTTCACACTGCAGTCTCCCGTTGCCCGATGCACACACCTTTAAGCAGCATCTGCAGGCACATCAGCAATCGATGGGCACATCTGTAACGGGTGGAGTCTCTAGTAATCCATCAGTTGGTGGAGGAACACAGAGCACAGGGTCTACATCCAGCTGTCAGAATGGTGGCAACTCAACCTCCTCTACAGGTGGCAATGGAGGAAATGCATCGGGGAGTGCCAATGCGGATCAGGACCGATTCCCACAACAATGTATCTGCTGTCGGCAAACGCTTAACTCTGAGTTTGAGATTAGTCTACATGCCAAATTCCACACTAAATCTCCGGATACCAACGAGCGTACGTGTGCCCTCTGTCTGGAACCACTACCGTCACAACCCGAATCCAACACCAAAATTTGTGACCCTTGTCTTAAGCGTCACAACTTCCCGTCGAAACTTCTCTCGATGAACTTCCTTAAACCTAGCGCCGCAACAACGTTAGGCCAAGCACCGACCATTGCAGGTCCTTCGCACGGTATCGTTGGACCTTCGAGTGTTCCTATCGAAGGACGGATAACAGCTTCTGGTGGCATCCAACAGCatgaacagcaacaaactgCTGGTCGGGACAATACGTCCTCCTCACCGTACCAGTGTAATCTTTGCAAGAAACCGCTACCATCGAGTCATAAGCTGCAGGAACATCTGATCGATCATACGTTTGCTGGCTGCGAAGAACGGGGCTATGTTTGCTACCTTTGCTCTGCCGTTTTTACCTCCTCCGCAGGGTTACAGGCCCATCTGCCAGTGGCACATTCGAACGCAGCAGCCAAACCGTACGACTGCGAGCGTTGTGGAGTGGCGTACTTCTTCCGCGCCGAACTAGAGCATCACCTGATCGATCACGAGCTGGGTAGGACGACGAGATCGGTGACTGGTGCGTTTGAACATTCGTCCACAGTGCGAACTGGAGATGACGAGTGGCGATCGGCACAAAATTCACCTACTTCGGAAGATGAAGGTTCAAGCGAGACTCAGAAGGGTCACATCAAGCAGGAACTTTCCGAAGCGGAACAGGAACAGGATGGATCATCACCGTACCACCATAAGGAGGATAATTCCGATGAGGATAATGAGGAATCAACGGGAAATGAAGAAGTTGGAGAGGCAGATGGAGTGAATGTGGAACAACAAATAGATGAGGAGGAGCATGAAGAGGTGGATCAAGTTGAGAGTGAGCATATGGAGGAAGAGGATGAAGAAGACGATGGAGACGCAACCAACGAAGGTGAAATGAGGGAAGAGACAGAGCcacaggaacaggaacaggaacaggatCAGGAAGATGAAGAGGAGTACATTGAAGTGGATGAACACACGACGATGGATGATGAAGGTGGAGGCAAAGCACCAACGCATACCGAACGTCTTCGAAGGAATTCGAACATGTTGATCAATGGTGGAAAAGATTGTTCAACGCTATCCACTACTACGACAACTCCGACTCTTCCTGTTGTTACTGCGGCTGAGTAG
Protein Sequence: MANGIVWCIDWLGWVAFVQAESGQNNPSDNASVRSGDSVERPLEMDDEEDKNDNEEIDDEADENDVDDVDDDDDDEIDDELLEDDDDEEGDHVRLDGTDARDVDDEFTSDSFCSELYSSHTSSSFSPSISDGMTTPNSITNDTNDGSMVGLGSTDEKPFRQGGNHHIHPRHHHHAHHRRTAGTGGGHPSSAKEGAKSSLKHHQLNNNNSSSHNHNNNNNNHGSNSKGLNSTYHCQFCEKTFPRLGYLKKHEQSHTEHMPFKCEYCARLFKHKRSRDRHTKLHTGDRRYRCLHCEAAFSRSDHLKIHMKTHDNQKPFQCTICNRGYNTAAALTSHMQNHKKQLALTGSPNLTYSPRSTTSSMSSGGGGGSGGKRGAKFSPYANDPLLLMSRGSSKLSSTLAKASSGNVSSNRTPTPGSTGAGSASGGPVSGGAHGDLLSCPYCTRTDFSTLEQLGLHVQSMHGHGALGLLGADTSMPYFTPGGRRAVTPDGNSLSLGGLGPYPPITCEFCTMKFPTVPLMFAHLKTSHLDRLAGAGLQRTSPNGTSISSPLGGSRPPSGFHSLEQLHFNKSLLGNAFPSFYGGMGAGSSTNVAGMSGESIKLEHRATASSNGRDENGNESSEAGRKRKRKGHDGEKDSNHGSGRKTDKQQEDAEAGDDDDIDDGDEDHLEENDGNRSSPVDLKELNSHDPESANIKQERKDETDQAIPEVASGSTSTRSSPCDSLGSIVHPTSHPSSERNSPAEQLTPTDLSQPKMKRLKLETLLEDEDVPEPDRKLPTVGSGRSHTREPHKQRSATTRREHEPKEPPQHQHMSVPQLHSSGSNVPQSQQLNASNSTASHHVHQLPGAYLCNQCNAALPDFESFRTHLKAHLEQSAANAAAAAAMRLTGDHSATGPAGSSNASSTSGASGGSLSLTTFLCQQCGATLSCQAEYEQHTIGHFLVMAVEYRCQAAGGGGSAGTSCTGKASFGKVEDLHKHLYEGHMQLLYKCTVCGETFDSKVQVQVHFAVSHSVEVKLYRCSACAEVFRSEREFRQHIRTRHLTAGAVQCMFCRMVCSSELEMHFHLASHARKFKCPACPESFHVEFLLDRHIQTHHSQKETSSPNRRESTVPSTVPSTTSNPSLSVTTSTGTSASTTASSSVAGLDYLHLHGQMAAMAAAAAWPSLYQTANKFYNNPLQVDTLNQLKHPQHLLHGFYDTMLGKAHQQQQRSSFLPDPTTGAGSTLGSKKNPFTGHSPNTSATNALLGLGYGTSSSGSSGTSQLQRSAGTHTLNGSATGLYSPEEGTNAGSVVPAGSAKLYSPIAMIQRYGDNGGLHSTGATAGGNNSTSRPGVESPTGQLLLASHTSLGLPEHHHSEQPGRKTTQQSTSKSSSTLTTSGTAPQMATTSSAGSCYSCGICERSDFSTESEVQTHRKIVHNLKTGVSLRCAYCNGDFRSRNELENHMKVAHNTGGGKHKCLICDEIFPSPAVLAEHKLSHCKVGASGRCSHCSLPLPDAHTFKQHLQAHQQSMGTSVTGGVSSNPSVGGGTQSTGSTSSCQNGGNSTSSTGGNGGNASGSANADQDRFPQQCICCRQTLNSEFEISLHAKFHTKSPDTNERTCALCLEPLPSQPESNTKICDPCLKRHNFPSKLLSMNFLKPSAATTLGQAPTIAGPSHGIVGPSSVPIEGRITASGGIQQHEQQQTAGRDNTSSSPYQCNLCKKPLPSSHKLQEHLIDHTFAGCEERGYVCYLCSAVFTSSAGLQAHLPVAHSNAAAKPYDCERCGVAYFFRAELEHHLIDHELGRTTRSVTGAFEHSSTVRTGDDEWRSAQNSPTSEDEGSSETQKGHIKQELSEAEQEQDGSSPYHHKEDNSDEDNEESTGNEEVGEADGVNVEQQIDEEEHEEVDQVESEHMEEEDEEDDGDATNEGEMREETEPQEQEQEQDQEDEEEYIEVDEHTTMDDEGGGKAPTHTERLRRNSNMLINGGKDCSTLSTTTTTPTLPVVTAAE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00101855;
90% Identity: -
80% Identity: -