Basic Information

Insect: Anopheles melas
Gene Symbol: zld
Assembly: GCA_000473525.2
Location: AXCO02001353.1:31900-35625[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.04 2.2 8.7 0.1 2 23 268 290 267 290 0.95

2 6 0.0033 0.18 12.2 2.9 1 23 555 579 555 579 0.92

3 6 0.49 27 5.3 5.5 1 23 1022 1045 1022 1045 0.94

4 6 0.047 2.5 8.5 5.2 1 23 1051 1073 1051 1073 0.97

5 6 2.8e-05 0.0015 18.7 6.7 1 23 1079 1101 1079 1101 0.98

6 6 1.2e-05 0.00062 19.9 0.8 1 23 1107 1129 1107 1129 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.04	2.2	8.7	0.1	2	23	268	290	267	290	0.95
2	6	0.0033	0.18	12.2	2.9	1	23	555	579	555	579	0.92
3	6	0.49	27	5.3	5.5	1	23	1022	1045	1022	1045	0.94
4	6	0.047	2.5	8.5	5.2	1	23	1051	1073	1051	1073	0.97
5	6	2.8e-05	0.0015	18.7	6.7	1	23	1079	1101	1079	1101	0.98
6	6	1.2e-05	0.00062	19.9	0.8	1	23	1107	1129	1107	1129	0.97

Sequence Information

Coding Sequence: ATGCACTACCATCAGCATGACAGCATGAATCGCTGGGGTTCGTCGCAGCAGCAGCAGCCAGTGGTCAGTACAACGCTTGCAACGACAGCGGTCGCGACGACGACAACGGCCGCCCCCATTACAACGAACGGCTCGGTTGTCCCTTCGTCCACGACGCCCACCTCCTCCGACACGGAGAACAACAACCAGCCCGGGTCGCTTACACCCACGGGCGGCTTGAAGCCGGTCGCTTCGCCGCAGCAGCAGCAGCAGCAGCACCATACGACGATAGCAGCGGCCGCTGACTCGAGTGATAATCAGCCGCCAACGCCACAGCCCACCATCACGGAGCCCGGAACTCCGCAAAGCTACAGTGGTGGTGGTGGACTGCCGAGCGGTGCGCCCGGCAGCGAGATGCACTATCCGAGCTACATCCATCCCGGGTACGACTACGCGTACGCCGGCGGCCCGGGGCTCGACTATGGCGGTGGTGGTGTGCTCGGCGCACCGCTCCAGCCGACCGACTACAAGTCCAGCTCGTCGGTCGTGTCGTCCGCCCGGTACCATCCGTACGGTGGGCCGGGAAGCAACGGCCCGGCGGACGGTTCGTCGCCGGCCGTGGTCAGCAGCAACGGTTCGGCTGGCATGAGCCCGCAGGTGGTAAGTTCTTCCAACGGGGTCAGCGTGGCCGGAAGTGGCAGTGCTGGAGCGGGCAGTGTAACGACGGTCGCCAGCACCACCTCCCAGTCGCAGTCGTCGCACTCGCCGCAGAATGGCACGGGCGGGTCGAACATTCCGCCGACTCCGTCCCCATCGCCGATCCAGTGCGAGAAGTGCGGGCTGGTGTGCGAGTCCGACGAGGCGCTGAACGAGCACGAGGCGACGGTTCATTCGAGCGTGCCGGTACAGTCGGCGCAGGATCAGCAGCAGCAGCAGCAGCAGCGTGTCGATCAGGTCGATCTACAAACTGGCGGTGGAGCGAACTGCTATCCGTACGGAGGTGGCGGCGGTACGCCCGGTTACCCCGTGAAGGAAGAGGCGCCCGCCAGCGACATCCTCGATCTCGACTCGCAGAAGATGGTTGGGTATGGGGCGGGCGCGGACGGCGGGCTCCTGCCACCGATGAACTCGCTCCACCCGCTGCAGTCGATGCAGCGCCACCCGATGATGGCCTGGCCGCACCACGACCCACACAACTTCATGGGGCCGCCGCCGCCGCTGCCCCCGCCGCCGCACCATGCCGGTGCCGATATGAAGCATTCCGCGGCGGCAGCAGCAGCGGCCGCCGCCGCCTACTACCACCACCCGATCAAGTCCGAGTACTCGGCCACCCCGTCGATCAAGTCCGAGTATCTCGGCGGCGGCGGCGTCGGTGGTGGCGGCCATTACGGTGCGCCCGGCGGTCCGATGGTGAAGAACGAGTACAGCCTCGCGCCCACGCTACCGCCGCCGGCCGTCGCACCGCAGGCGACGAACCCGCAGTCGATGAAGCAGTACGCGGACGAGATGCACGACAATCAGCTCGCGACCAGCCCGTCCGACTTCCCGAGCACGACGACACCGCAGGAAAGTGGCTCCCAGTATCGGACGTTCGAGCCGGCCACCTCCTCGCTGCCGGGGACGGGCTCGGGCCCAACCAAGGGCACGGCGTGGAAGTCGAACGAGGCGCGCCGCCCCAAAACGTACAACTGTACCGCGTGCAACAAGTGGTTCACTAGCTCGGGCCACCTGAAGCGGCACTACAACACGACGCTGCACAAGAACGCGGTCAAGTCGAGCGGCCAGCCCGACCCGGCGACGCTGCCGATCAGTGTGCACCATCATCCGGGGCGCGATCCGAACTACGCCAACAAGGGGCGGCGCGGTGGGACCGGCAACGGTGGCGCCGGCGGTTCCGGCGGAGGCGGCGGCGCCGGTGGCGGTGGCTCCCAGCTGCAGCAAACGATACAGCAGCCGGTACCGCCGCCCGACCCGCCCAGAAGTCCCGAGTACGGGGCGGTCGGCCAGCAGTACGCGGGGGCGGGGTTTCCAGCGGCCGGGACATCGCCCGGCCAGCAGCATCCGGGCGGCGGCCAGCTAGTCAGCACGAACCAATCGGCGGGGTTTCACCACCCGTACGCCGGCGCGACCAGCGCGAACGGCGGCAGCACGTCGGCGAGCAGCTCCACTTCTTCAGCGGTTCCCCCAAACGGGCAGCCCATCTGCACGGCGGGCATCCCGGACATCCCGGGCACCACCATCTGCACGGGCACGCGCACCCCGGGCACCCCGGGCACCCGCACGCCCCCCACCATGGGCATGGGCTCGCCGCAGCCGCCGCCTCACCATCTGCAGCAGCGGCAGCAGCAGCCGCCGCCGCAGCAGCAGCTGCCGCCGCCCACCATCAGTTCAATGGAGCCCTACCACCACCACCACCACCACCACATGCAGCCGCACACAATGCACACGCACATCTCCAATCCTTTAACTATCAGCACCACCAGCATTCCATCCTTCCAAACCATCCTGCCGGAGGCGCCGAGCTATCACCTTATTATTGGTAATGGGCCGCAGTACCACCCGGGGGGACAGGGGGGCCATCATCAGCTCCACCAGCCGGCGGGGGACGGTGGGCAGTGGGCGGACCTGCCCACCGATGGGACGGAGGGGCTGATCGAGTCGACGACGGGCGGACGCACGCCGTTGGGGTTTCCCCGATGTGCGGGGGGCGCCGAGGTGTATCAGGGCGATACGGCGCCCCCCTTCTCACCTAACGTACCGGAGCAGTACCACCACCAGCAGCAGCAGCGGTCGGGGGGTGGTGAGGCCGGCCTACCCATCGGCATGACGATGCTGCACGACGGCCAGCTGACGACCGAGTCCGGCAAGTACAAGGACTACCTGCAGTCCGAGGTCGACTCGTACCAGGAGCAGCTGCTGTACCGGGTGGCCACCCCGCCGCTGGGCGCCACCGCACCATCCATCTCGCCCGCGCCCTGCTCCCCGAGCGTCACCTCGACGGACGTCGGGCAGACGCAGCTAGTACGAGCGCGGGGCCAGAAAGCGGGCCAACACGGCAGCGCGAACGGACAGGCGCCGGAGATCCACCGGTGCATCGAGTGCGACAAGGTGTTCAACAAGGTGTGCTACCTGACGCAGCACAACAAAACGTTCCACTCGGGCGACAAACCGTACAAGTGTCACCGGTGCGGCAAGCGCTTCCCCTGCAACCAGTCGTACGAGGAGCATCTGGCGAAGCACGGGGGCGAAAAACCGTTCAAGTGCGAGCAGTGCCCGAAGCAGTTCAACCACAAGACGGACCTGCGGCGGCACATGTGCCTGCACAGCGGCTCGAAACCGTACGCCTGCGAGCAGTGCGGCAAGGGCTTCATCCGGAAGGACCACATGATGAAGCACGCGGAAACGCACCGGAAGAATGCGGCGGCGGCAGCGGCGGCGGCGGCCGCCGGCCACGACGGCCCGAAGCGCCCCGGCAAGGGGCAGGGCGTCATCAAGGGCGGCGGGCGCAAGATCGTCGGCCTGATGGACGAATGA
Protein Sequence: MHYHQHDSMNRWGSSQQQQPVVSTTLATTAVATTTTAAPITTNGSVVPSSTTPTSSDTENNNQPGSLTPTGGLKPVASPQQQQQQHHTTIAAAADSSDNQPPTPQPTITEPGTPQSYSGGGGLPSGAPGSEMHYPSYIHPGYDYAYAGGPGLDYGGGGVLGAPLQPTDYKSSSSVVSSARYHPYGGPGSNGPADGSSPAVVSSNGSAGMSPQVVSSSNGVSVAGSGSAGAGSVTTVASTTSQSQSSHSPQNGTGGSNIPPTPSPSPIQCEKCGLVCESDEALNEHEATVHSSVPVQSAQDQQQQQQQRVDQVDLQTGGGANCYPYGGGGGTPGYPVKEEAPASDILDLDSQKMVGYGAGADGGLLPPMNSLHPLQSMQRHPMMAWPHHDPHNFMGPPPPLPPPPHHAGADMKHSAAAAAAAAAAYYHHPIKSEYSATPSIKSEYLGGGGVGGGGHYGAPGGPMVKNEYSLAPTLPPPAVAPQATNPQSMKQYADEMHDNQLATSPSDFPSTTTPQESGSQYRTFEPATSSLPGTGSGPTKGTAWKSNEARRPKTYNCTACNKWFTSSGHLKRHYNTTLHKNAVKSSGQPDPATLPISVHHHPGRDPNYANKGRRGGTGNGGAGGSGGGGGAGGGGSQLQQTIQQPVPPPDPPRSPEYGAVGQQYAGAGFPAAGTSPGQQHPGGGQLVSTNQSAGFHHPYAGATSANGGSTSASSSTSSAVPPNGQPICTAGIPDIPGTTICTGTRTPGTPGTRTPPTMGMGSPQPPPHHLQQRQQQPPPQQQLPPPTISSMEPYHHHHHHHMQPHTMHTHISNPLTISTTSIPSFQTILPEAPSYHLIIGNGPQYHPGGQGGHHQLHQPAGDGGQWADLPTDGTEGLIESTTGGRTPLGFPRCAGGAEVYQGDTAPPFSPNVPEQYHHQQQQRSGGGEAGLPIGMTMLHDGQLTTESGKYKDYLQSEVDSYQEQLLYRVATPPLGATAPSISPAPCSPSVTSTDVGQTQLVRARGQKAGQHGSANGQAPEIHRCIECDKVFNKVCYLTQHNKTFHSGDKPYKCHRCGKRFPCNQSYEEHLAKHGGEKPFKCEQCPKQFNHKTDLRRHMCLHSGSKPYACEQCGKGFIRKDHMMKHAETHRKNAAAAAAAAAAGHDGPKRPGKGQGVIKGGGRKIVGLMDE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00102671; iTF_00093776; iTF_00095964; iTF_00101269; iTF_00107289;
90% Identity: iTF_00102671;
80% Identity: -