Amel011499.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles melas
Gene Symbol
-
Assembly
GCA_000473525.2
Location
AXCO02012762.1:4529-6589[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 4 2.2e+02 2.5 8.7 1 23 229 251 229 251 0.98
2 11 0.00014 0.0076 16.5 5.4 1 23 259 282 259 282 0.97
3 11 9.4e-05 0.0051 17.0 1.7 1 23 285 307 285 307 0.97
4 11 0.0036 0.19 12.1 0.4 1 23 313 336 313 336 0.98
5 11 2.8e-05 0.0015 18.7 0.7 2 23 343 364 342 364 0.97
6 11 0.00022 0.012 15.9 7.4 1 23 370 393 370 393 0.95
7 11 0.00017 0.0091 16.2 2.1 1 23 398 421 398 421 0.96
8 11 0.057 3.1 8.3 0.8 1 23 427 449 427 449 0.95
9 11 0.65 35 4.9 0.2 2 21 456 475 455 476 0.93
10 11 6.2 3.3e+02 1.9 2.0 6 23 485 503 485 503 0.92
11 11 0.0023 0.12 12.7 1.0 2 22 531 551 531 551 0.96

Sequence Information

Coding Sequence
ATGGCTGCATTCCGGCTCGAACACTTTCCAAATGTGTGTCGCATATGCTTGCAGCACCAGCCGGAGAATGTACTTATTTCAGTGGAATCGTTGCATTACAACCATGTGAAGATGATCGATGTGATAGACGAGCTGATGGGTCCCGTGTTACCGGAGCTGCATCACCATACTCCATCCGGTATTTGTGAACCATGCTCCACAGAACTGATCGCTTTTCTAAACTACCGAAATCGGCTAAAACTCGTAGGGAAGTTTGTACATGCCCTGGTTCATTTGAGAAACGATCACACAGTACCGCTGGACAATGTCTTTCGAGATCATCAGACGGAATTGTTGAGTGTATTGCACGAGCTAAACATTACCGATAAACTTGAGCTAGTCGTTCAAGATTTGATAGATGCATTCAAGGTGGCGCAGGACTCAATGCATGACGCTGAACGAACAGAACAGAGCTACACACCATTCCAACAAACAACGAGCGACGATATGATTGCAAGTCCAACACCCGAAGAGTTTGAAATGTTTGAGTTGGATGAAGAAATGCTCCCCGAAGGAACGAACGATCGCAATGAAGATGATAATGTTGAAGATTCTGTCGACATGTTGGAGGCAATAGGCGTTGCAAATTCGGCGGAAAATAAATCTACCAGAACCCTACGAAGTAGCCGACAGAAAGGAGTAATGCATCAGTGTCAACATTGTCCATTTACAACACATCTGCTGAAAGCGTTTAAGCAGCACACGAAGACGCATGAAAGCAAACAACCCACCCAACACACCTGCAAGCGTTGCAACGAAACGTTCACCACAAAGCGCGACTTGCTGCAGCACAAACGGTCCACCCATCGGGATCACATGTGCGATACGTGCGGGTTAGCGTTCGACACCAAGTTTGCGCTGGAAACGCACCGCAAACGGCACGAACCGGTACGCCCGTACAAGTGCGAATACTGCCCGCTGGAGTACTACACCAAGGCGGAACAGCTGCTGCACGTTCGCCGGCTGCATCTGAAAGCGTTCGAGGTAAGCTGCACCGAGTGTGCGCTAACGTTCCGCACGAAGCAAATGCTTGCGCAGCATATGAAAACGCACACGAACCAACGGACGCACACGTGCACTGTTTGTGGGTTTAGCTTTAAATCACATACGCACCTGAACCGGCACACGAAGGAACTGCACCGCGGGGTGGTGTATGAGTGTGAGCATTGCAGCGCGTCGTACCGGCGCAAGGATAAGCTCCGAATGCACGTGGAAAAGATGCATAATATTCAAACGTACTTTGTCTGTGATATTTGCCTCCAATCGTACGATACGGATGAAAAACTGCAAGAGCACAAAGCGCACCATCAAAATCCGAAAGATTTACAGTGTGGAGTGTGTCTGGGGGCGTACAAGACGAGGGAGGAATTCAACGACCATCTATGTATCACGTATCGTGAAAACTACATATGCTGCGAGCGCGATTTTAGGTATCACTTTTTCTACAACAAACACATGTTCCTGGCGCACAGACAGCAGACGAACGTGCGCGTCAAACCCGCGGATGGCATGCTGCTGGGACAGTATCGTGCAAAGCGGAAACAAGCAGAACGATGTCCAACATGCGAGCAAGAGTTCCCAACCCGACAGCAGAAGAAAAAACACATGCGAAGCTGTGGCGCGTTGGAGTACGAGGTCGTTGAGGTTTTTGCGCCCGAGGACAATGGGAGTGTTACCATCGGTGGGGAATAG
Protein Sequence
MAAFRLEHFPNVCRICLQHQPENVLISVESLHYNHVKMIDVIDELMGPVLPELHHHTPSGICEPCSTELIAFLNYRNRLKLVGKFVHALVHLRNDHTVPLDNVFRDHQTELLSVLHELNITDKLELVVQDLIDAFKVAQDSMHDAERTEQSYTPFQQTTSDDMIASPTPEEFEMFELDEEMLPEGTNDRNEDDNVEDSVDMLEAIGVANSAENKSTRTLRSSRQKGVMHQCQHCPFTTHLLKAFKQHTKTHESKQPTQHTCKRCNETFTTKRDLLQHKRSTHRDHMCDTCGLAFDTKFALETHRKRHEPVRPYKCEYCPLEYYTKAEQLLHVRRLHLKAFEVSCTECALTFRTKQMLAQHMKTHTNQRTHTCTVCGFSFKSHTHLNRHTKELHRGVVYECEHCSASYRRKDKLRMHVEKMHNIQTYFVCDICLQSYDTDEKLQEHKAHHQNPKDLQCGVCLGAYKTREEFNDHLCITYRENYICCERDFRYHFFYNKHMFLAHRQQTNVRVKPADGMLLGQYRAKRKQAERCPTCEQEFPTRQQKKKHMRSCGALEYEVVEVFAPEDNGSVTIGGE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00093749;
90% Identity
iTF_00093749;
80% Identity
-