Basic Information

Insect: Anopheles melas
Gene Symbol: PPP2R5C
Assembly: GCA_000473525.2
Location: KI919696.1:10972-17693[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 2.7 1.4e+02 3.0 1.6 2 23 214 236 214 236 0.94

2 17 0.0025 0.14 12.5 0.1 2 20 246 264 245 266 0.94

3 17 0.14 7.4 7.1 0.8 1 20 273 292 273 294 0.95

4 17 0.6 33 5.0 3.1 2 23 419 441 418 441 0.92

5 17 4.5 2.4e+02 2.3 1.5 3 21 455 473 453 474 0.92

6 17 0.019 1 9.8 1.6 1 21 481 501 481 506 0.92

7 17 0.0015 0.083 13.2 1.3 3 23 584 605 583 605 0.90

8 17 2.6 1.4e+02 3.1 0.1 1 20 618 637 618 639 0.87

9 17 0.033 1.8 9.0 2.8 1 21 648 668 648 673 0.92

10 17 0.017 0.89 10.0 0.9 2 23 737 761 736 761 0.84

11 17 4.8 2.6e+02 2.2 0.6 2 20 778 796 778 798 0.92

12 17 0.0024 0.13 12.6 0.3 1 23 805 828 805 828 0.94

13 17 4.1e-05 0.0022 18.2 0.1 1 23 835 857 835 857 0.98

14 17 3.3e-05 0.0018 18.4 2.4 1 23 863 886 863 886 0.96

15 17 0.00019 0.01 16.0 0.6 1 23 892 914 892 914 0.98

16 17 0.013 0.73 10.2 2.5 1 23 920 943 920 943 0.93

17 17 3e-05 0.0016 18.6 0.7 1 23 949 971 949 971 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	2.7	1.4e+02	3.0	1.6	2	23	214	236	214	236	0.94
2	17	0.0025	0.14	12.5	0.1	2	20	246	264	245	266	0.94
3	17	0.14	7.4	7.1	0.8	1	20	273	292	273	294	0.95
4	17	0.6	33	5.0	3.1	2	23	419	441	418	441	0.92
5	17	4.5	2.4e+02	2.3	1.5	3	21	455	473	453	474	0.92
6	17	0.019	1	9.8	1.6	1	21	481	501	481	506	0.92
7	17	0.0015	0.083	13.2	1.3	3	23	584	605	583	605	0.90
8	17	2.6	1.4e+02	3.1	0.1	1	20	618	637	618	639	0.87
9	17	0.033	1.8	9.0	2.8	1	21	648	668	648	673	0.92
10	17	0.017	0.89	10.0	0.9	2	23	737	761	736	761	0.84
11	17	4.8	2.6e+02	2.2	0.6	2	20	778	796	778	798	0.92
12	17	0.0024	0.13	12.6	0.3	1	23	805	828	805	828	0.94
13	17	4.1e-05	0.0022	18.2	0.1	1	23	835	857	835	857	0.98
14	17	3.3e-05	0.0018	18.4	2.4	1	23	863	886	863	886	0.96
15	17	0.00019	0.01	16.0	0.6	1	23	892	914	892	914	0.98
16	17	0.013	0.73	10.2	2.5	1	23	920	943	920	943	0.93
17	17	3e-05	0.0016	18.6	0.7	1	23	949	971	949	971	0.99

Sequence Information

Coding Sequence: ATGCTGCGAAGACCGTCGAAGCGAAGAAAAGTGTCCAACATGGATGAAGAAGAAACGGAATTCACGCCAGCGTCGGTTGAGCAGAAATGCTGCATCTGCTCCAAACATCCGAAGGGCGATTTGCTTGAACTTTCCACTGTTGTAGAATCGGGCAGCTCCCTCACCATTGCCACCGTCGTCGAACAGGTGGCCTCCATCAAGGTAAACAATGTCCAGAAGAGCATTTGCGGTGGTTGTTGGACCAAAATTCAGGCGGCCTACTCGATACAGAAGGAAATCCGTGGATCGGAATGTATGGTGCAGCAGGATGTCGAGTGCGACAGTGAGGAAGAGGAAGAGAGCGCGGAAAATGCCAACTGTACCGAGAAGGACCATCCGGACCCGCTCGTCGTAGATAGCATTGACGAGAGCGAATATTGCATCGAATATCTGGAGGAACAGGCGGAAGAGCAGCAACCACCAGCAAAGGAAGAAGCGGCAGACATTGAGATTGAAGCATGCTGCTCCGACGAGGAAGAGCACGAAGAGCTCCGAGCGGACGGTGGTAAGGTGACGCGTCAGTTCCAAATGCCAAATGAGGCCACGATCGTGGCCGACGTACTGCACGAGCAGTATCGGATAGTGGAGGTAACCGGGGAACGGTGCTGCGGATGCAGCTTTGTCGCACGATCACGCAAAGAGCTGCTGCAACACTCGGAAACGGTCCACACGGTCGAGATGACCGACCACGGCGACTACTGTCCGATTTGTTTCTACAAATTCTCCACCGATCAGCAGCTCGAGCGCCACATCGATGAGTTTAAGCTGAACAAGATGTACGTGTGTTTGCGCTGCAATCGGTTCTACAACGTGAAGCGGAAGCTGTTCAACCACCTGCTCGAATGTGGTGGCATGGTTGAGGAGGTGGATGTGCAGGCAAGCGGAACGAACAATGATGATGCACTTACGATCGAAGCCCTGAAAGAGGAGGACGGGGAAGAGGAGGAAGGGCTGGAGGAAGATAGTCAGTATGAGGAGTGTTACCTGCAGGAAGGCACTGACACGGACGAACAGCAAGAGCTGCACGCGGAGGACCGCCTACAGAACGCAACCGATCCACGTGTGATGCATCGCTACAAAGCGCTGTTCGAAGAGGTGCTGTCGAACGAAGAGCTTTACTGCCAGCTGAGCGAGAAGGAACTGAACGTGCAGGATGTGCAGATCGCGGAGCAGCACGTGTTCGAAACGTTCAAGTACATTCGGTTGCGCGGATTGCGCTGTTGCGGGTGCTCCTACACCTGCATGTCCAAGGCGTTGCTGATTAAGCACAGCAATCTGGCCCATCCGCCCGAAAATCCGTCGGAGCACGTGGATGAGCATTTGTGCGAGCTATGCCGGGCGGAGTTTCAAAACACGCTGAATCTCGTGAAGCATATCTGCTTCTTCACCACCCGGCAGCTGTTCCTGTGCACGGTGTGTGACGTTTCGTTTCTAAACAAGGAAAGCTTGCGGAACCACCAGCGCCACAACGAACGGCACCGCGAGCTGGAAAACTACAAGTTTGAGCAGGCCGGCATCGAACTCGACACAGCGGAAGGGTTCGTCGAGCTCGACCAGCCGGCCGTGGCGGACGAGCTGCGGAAGCTGGTGGTGGAAAAAATTAGCTACCGGCCGAAAGCGGTCACCTGCATTCCCATGCCGGACGAACGGTTCATCCGGCGAAGGAAGGAGTACAACAACTACAGCGTCCTGGTCGTGGCTGGCGAGTATTGCTGCGGGTGTGGCAAGTTCTTCGATACGACTTCCGAGCTGCAGCAGCACGCCGAGCAGGAGCACTATTTGCCGCTCAACTTTTGTGCCCGCACGTACGGCCACCAGTGCGAGATCTGTTACGCCGTGTTTGAGCTCGAACGGGGCTTCGCGGTGCACCGGTCGATGAGTCGGTCCAAGCAAAAGACGCTGTACCTCTGCAAACTCTGTGGGCTGCTGTTTTCGAAGAAGTTCTGCCTAGCGCGGCACATGCATTCGGCCCCGAACCACCTGTCGCGGCTGATCGTTGATGCAGCGGCTAATGCCACAGGGAAGGAGCACGATGCGCCGGAGGAAGCAGACGCGGAACCGGGTCCACCCGAGGCAGCCGTATCGGATCCACGCGTGAAGGAAGCGCTACAGTTGCACCGGTCGGTGGAAGCGAAAGGGCTGCGAAAGGTCGGCCATCTCGTCTGGTACCACTGCTGCTTTCCCAAGTGTCCGGAGACGTTCACGAGCGAAGCGGCACTGCAGGAGCACGCCCAGGCCGAGCACTACGGGCAGCGGCGGGAAAACCAAAACGAGCGCCAGCAGGACACGAACGTGTGTCCTACCTGCTGCAAACCGTTCCAAACGCTGGCGAAACTGTACTGGCATCGGGTGAAACGGTTCGTGCCGCGCGAGTATAAGTGCAAGCAGTGCGCCAGCACCTTCGACCGTTGGGTGCAGCTGAAAATCCACGTGGAGCAGGAGCACAGCGCCACGCCGCCCAGCTTCGAGTGTGCCGAATGCGGCAAATCGTTCGTGCTGCGGGCGAGACTGGTCGCCCACCAGAAGACGCACACCGACCGGAAGGACCACAAGTGCGACGTGTGCGGGTGTGCGTTCGTCAGCAAGGGGCTGCTGAAGCGGCACCGGCGAGCGCTCCACGCCACCGAGCTGCTGTTTGAGTGTAAGCTGTGCTCGAAAAAGTTTGCCGTGGTGGAGAAGCTGAAAATTCACCAGCGCGTCCACACGGGCGAACGCCCCTACGAGTGTACGTTCTGCTCGCGCACCTTCATACACTTTTCCGACCGGAAGCGGCATGAGATGGCAGCGCACACCATGGAACGCCCGTACAAGTGCAAGCTTTGCCCGGCGTCGTACATACGCAACCGTGAGCTGAATCTGCACATGCAAAAGCACCAGTCGGATGGAAAGGAGAAAAACCTCGTTAAAATGTTTAGTGTTTCGCTTCGTCCGGTCGTGTGTGCGTGTGTACGGTTCGTCTCCGGTTCGTCTCCGGTTCCGGAAGGTTTCAATCCGTGCCTAGTACAAATCGTCGATCGTCGTCGAAAGCTGCAGGAGGAGGGAGCTGCCAAACATAAGGGGTTATTTTACGAGATCGAAACGCTGCCCCCGCTGAAGGACGCCGATCCGGCCGAGCGGGAGGAGCTGTTTATCCAGAAGCTGCGCCAGTGCTGCGTCCTGTTCGATTTTTCTGAACCGCTGAACGATCTGAAGTACAAGGAGATCAAGCGGTGCGCGCTGCAGGAAATCGTCGAGCATCTGAATAACCAGAGCAACGTGATTACCGAGCCGATCTACCCGGAAGCGTTCAACATGGTGGCGACCAACCTGTTCCGCACGCTGCCCCCGTCCTCCAACCCGAACGGGGCCGAGTTCGATCCGGAGGAGGATGAGCCGACGCTCGAGGTGTCCTGGCCGCATCTGCAGTTCGTGTACGAGCTGTTTCTGCGGTTTCTCGAGTCGCCCGACTTCCAGCCGAACGTGGCGAAGCGGTACATCGACCACAGCTTCATCCTGAACCTGCTCGAGCTGTTCGATTCGGAGGATCCGCGCGAGCGCGACTTCCTCAAGACGGTGCTGCACCGGGTGTACGGCAAGTTTCTCGGGCTGCGCGCCTTCATCCGCAAGCAGATCAACAACATCTTCTACAAGTTCATCTACGAGACGGAGCACCACAACGGCATTGCCGAGCTGCTCGAGATACTGGGCAGCATCATCAACGGGTTCGCGCTCCCCCTGAAGGAGGAGCACAAGCAGTTCCTGCTCAAGGTGCTGCTGCCGCTGCACAAGGTCAAGAGCCTGTCCGTGTACCATCCGCAGCTGGCGTACTGTGTGGTGCAGTTTCTCGAGAAGGACGCCAGCCTGACGCAGCCCGTCATCAAGTGTTTGCTCAAGTTTTGGCCGAAAACGCACAGTCCGAAGGAGGTGATGTTTCTGAACGAGCTCGAGGAGATACTGGACGTGATCGAGCCGGCCGAATTCCAGAAGGTGATGGAACCCCTGTTCCGCCAGATCGCCAAGTGCGTCTCGAGCCCGCACTTTCAGGTGGCCGAGCGGGCACTGTACTACTGGAACAATGACTACATCATGTCGCTGATATCGGAAAACTCGAAGGTAATCATGCCGATCATGTTCCCCGCCCTGTACAGCAACAGCAAGTCGCACTGGAACAAAACGATCCACGGGCTGATCTACAACGCGATCAAGCTGTTCATGGAGATGAACCAGCTGCTGTTCGACGAGTGCCACCGGAAGTACCAGGCGGAGCAGGAGACGGAGCAGGAGAAGCTGGCCCAGCGGGACGCCCTGTGGCAGCAGATGGAGGATCTGGCCGCGCGGAACAGTAAGTTGACGCTGAACGACGACGAGCAGCAGTCGGGCAGTGGGCGACTTTCGAGCAGCTTTAGCCACCCTCAGCAGCAGCAGCAGCACCGACAGATGAACGGAACGTCGGGTGGTGGTGGTGGTGGAGTGTACGATCGTCGATCGATACAGCACAGTAGCACCTAA
Protein Sequence: MLRRPSKRRKVSNMDEEETEFTPASVEQKCCICSKHPKGDLLELSTVVESGSSLTIATVVEQVASIKVNNVQKSICGGCWTKIQAAYSIQKEIRGSECMVQQDVECDSEEEEESAENANCTEKDHPDPLVVDSIDESEYCIEYLEEQAEEQQPPAKEEAADIEIEACCSDEEEHEELRADGGKVTRQFQMPNEATIVADVLHEQYRIVEVTGERCCGCSFVARSRKELLQHSETVHTVEMTDHGDYCPICFYKFSTDQQLERHIDEFKLNKMYVCLRCNRFYNVKRKLFNHLLECGGMVEEVDVQASGTNNDDALTIEALKEEDGEEEEGLEEDSQYEECYLQEGTDTDEQQELHAEDRLQNATDPRVMHRYKALFEEVLSNEELYCQLSEKELNVQDVQIAEQHVFETFKYIRLRGLRCCGCSYTCMSKALLIKHSNLAHPPENPSEHVDEHLCELCRAEFQNTLNLVKHICFFTTRQLFLCTVCDVSFLNKESLRNHQRHNERHRELENYKFEQAGIELDTAEGFVELDQPAVADELRKLVVEKISYRPKAVTCIPMPDERFIRRRKEYNNYSVLVVAGEYCCGCGKFFDTTSELQQHAEQEHYLPLNFCARTYGHQCEICYAVFELERGFAVHRSMSRSKQKTLYLCKLCGLLFSKKFCLARHMHSAPNHLSRLIVDAAANATGKEHDAPEEADAEPGPPEAAVSDPRVKEALQLHRSVEAKGLRKVGHLVWYHCCFPKCPETFTSEAALQEHAQAEHYGQRRENQNERQQDTNVCPTCCKPFQTLAKLYWHRVKRFVPREYKCKQCASTFDRWVQLKIHVEQEHSATPPSFECAECGKSFVLRARLVAHQKTHTDRKDHKCDVCGCAFVSKGLLKRHRRALHATELLFECKLCSKKFAVVEKLKIHQRVHTGERPYECTFCSRTFIHFSDRKRHEMAAHTMERPYKCKLCPASYIRNRELNLHMQKHQSDGKEKNLVKMFSVSLRPVVCACVRFVSGSSPVPEGFNPCLVQIVDRRRKLQEEGAAKHKGLFYEIETLPPLKDADPAEREELFIQKLRQCCVLFDFSEPLNDLKYKEIKRCALQEIVEHLNNQSNVITEPIYPEAFNMVATNLFRTLPPSSNPNGAEFDPEEDEPTLEVSWPHLQFVYELFLRFLESPDFQPNVAKRYIDHSFILNLLELFDSEDPRERDFLKTVLHRVYGKFLGLRAFIRKQINNIFYKFIYETEHHNGIAELLEILGSIINGFALPLKEEHKQFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDASLTQPVIKCLLKFWPKTHSPKEVMFLNELEEILDVIEPAEFQKVMEPLFRQIAKCVSSPHFQVAERALYYWNNDYIMSLISENSKVIMPIMFPALYSNSKSHWNKTIHGLIYNAIKLFMEMNQLLFDECHRKYQAEQETEQEKLAQRDALWQQMEDLAARNSKLTLNDDEQQSGSGRLSSSFSHPQQQQQHRQMNGTSGGGGGGVYDRRSIQHSST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -