Amel013481.1
Basic Information
- Insect
- Anopheles melas
- Gene Symbol
- -
- Assembly
- GCA_000473525.2
- Location
- AXCO02010831.1:3564-5256[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 0.088 4.7 7.7 5.1 1 22 171 193 170 195 0.88 2 9 0.0017 0.093 13.0 0.4 1 23 207 230 207 230 0.92 3 9 0.044 2.4 8.6 1.0 2 21 257 276 256 279 0.89 4 9 8.4e-05 0.0045 17.2 0.8 1 23 320 343 320 343 0.92 5 9 1.5e-05 0.00082 19.5 1.2 1 23 349 371 349 371 0.97 6 9 1.7e-05 0.00091 19.4 2.3 2 23 377 398 377 398 0.97 7 9 3.4e-07 1.8e-05 24.7 2.9 2 23 405 426 405 426 0.97 8 9 0.082 4.4 7.8 2.5 3 23 434 454 434 454 0.99 9 9 0.00063 0.034 14.4 0.2 1 20 460 479 460 481 0.94
Sequence Information
- Coding Sequence
- ATGAGTCTTCAGTGTCGTGTTTGTTTGGACGCGCTGAGCAATGCTTACTATCTGTTCGAGGTGACCGGTGGCACCACACTGGCCGAAATTATACAATTCTGCGCCCAGGTTCAGATTGCCGAAGATGATGGACTGCCAACGTTTATCTGCCCAGCATGCTGTGAAGATGCTCAGCAAGCCTTTACATTCGTCCAGAAGGCTCGCCAATCGGACCACGAACTACGAGCGTCAAGAAGCATTACCCAGCAACCTGTGGCAGAATCGAATGTGGAGATGCAAGAGTTGGTGGTGGAATTGCTAATGGATTCCGATGAAATCCACAACCAACTGTATCCGGTCGAGTTGCTGGAAGAACACTTTGATCTGACCAGTGATACAGAGTGTGCCCTTGATCTGACCAGTGAGCAGAGTGAGGAAAACTTGCCAGATTTGGAAATTGTTCCTGCTCTCGCGGACCAGGATGAGGAAGGGGTCAGCTTAGCGACAAACAACGGCAATGGTCCGTGCTATTACTGTTGCCACGAGGACTGTCTGCTAACGTTTCACACAAAGAATGCGCTGAAACGTCACGTCGGTTTAAATCATCCAACAGAACAGCACAGTGCGCCGAACGTACAGCATCGTTGTGATAATTGTGATCGTGGATTTGCCACCGCGGAGGATCAACGCATACACCAGACGGCTCTCCACCTGAAACGGACCATAGTGAGTTCGTCCTGCAAGGGACGCCCAAACACACGCCTTTCCCTGTTCACGGCGACGGAAAAGAAGTGTTGCGATTGTTTCGCCTCCTTCCCCACGCTAGAGGCACTGCTAAAGCATGCTGTTCAGCAGCACTCCATTCGGAAAGCGGTGCACGATCCCACGCGTCCAGTGCGGTGCGAGGTGTGCTTCAAACTGTTCCGCTGCCGTACGAAGCGTAACTATCACCAGAGCATACCGTACAAACCGCTCCGGTACCGGTGTGGCACGTGTGACGCCTGCTTTCGAACCTCCGCACAGCTTGAAACGCACGAAATCGAACAGCACAGCACGGAACAGAAGTACGTTTGCGGGAAGTGTGGCGCTTGCTTCAAGAGCGCCCAAAACCTTAAAATGCACACACTGTTGCACGAGGAGAAGCGCGAAGTTTGCAAGACGTGCGGGGTTCGGTTTCACCGGAAGTCGAACCTACGCATCCACGAGCGCGTCCACTCAAACACGTACTACGCGGTGTGTCCACACTGTGACAAGAAGTACAAAACTCAGTCGCAGCTAAAGCAACACCTGAAGGTGCACACGCAGGAACGATCGCTCGGCTGCCGGTACTGTGCGAAGCGGTTCATGTACACCAGCGATCGGAAGCGGCACGAGATGACGCACACGGGCGAGTATCCGTTCGTGTGTGGCGGTTGCTCGAGAAAGTTCAGTCGCAGTAGGCTGTACACGCAGCATGTCGCCGTGTGCAAAGCTGCAGCAAAGGACGAAGCATAG
- Protein Sequence
- MSLQCRVCLDALSNAYYLFEVTGGTTLAEIIQFCAQVQIAEDDGLPTFICPACCEDAQQAFTFVQKARQSDHELRASRSITQQPVAESNVEMQELVVELLMDSDEIHNQLYPVELLEEHFDLTSDTECALDLTSEQSEENLPDLEIVPALADQDEEGVSLATNNGNGPCYYCCHEDCLLTFHTKNALKRHVGLNHPTEQHSAPNVQHRCDNCDRGFATAEDQRIHQTALHLKRTIVSSSCKGRPNTRLSLFTATEKKCCDCFASFPTLEALLKHAVQQHSIRKAVHDPTRPVRCEVCFKLFRCRTKRNYHQSIPYKPLRYRCGTCDACFRTSAQLETHEIEQHSTEQKYVCGKCGACFKSAQNLKMHTLLHEEKREVCKTCGVRFHRKSNLRIHERVHSNTYYAVCPHCDKKYKTQSQLKQHLKVHTQERSLGCRYCAKRFMYTSDRKRHEMTHTGEYPFVCGGCSRKFSRSRLYTQHVAVCKAAAKDEA
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00101187;
- 90% Identity
- iTF_00101187; iTF_00095883; iTF_00107217; iTF_00093694;
- 80% Identity
- -