Basic Information

Insect: Anopheles melas
Gene Symbol: -
Assembly: GCA_000473525.2
Location: AXCO02004511.1:3205-4399[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 7.6e-07 4.1e-05 23.6 0.0 3 23 49 69 47 69 0.95

2 8 9.8e-06 0.00053 20.1 1.3 1 23 75 97 75 97 0.95

3 8 9.6e-05 0.0052 17.0 1.6 1 23 103 126 103 126 0.96

4 8 0.0025 0.13 12.6 1.7 1 23 138 161 138 161 0.95

5 8 0.0066 0.36 11.2 1.0 1 23 233 255 233 255 0.97

6 8 8.5e-07 4.6e-05 23.5 1.2 1 23 261 283 261 283 0.96

7 8 2.7e-06 0.00015 21.9 0.8 1 23 290 313 290 313 0.96

8 8 0.72 39 4.8 8.6 1 23 320 343 320 343 0.86

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	7.6e-07	4.1e-05	23.6	0.0	3	23	49	69	47	69	0.95
2	8	9.8e-06	0.00053	20.1	1.3	1	23	75	97	75	97	0.95
3	8	9.6e-05	0.0052	17.0	1.6	1	23	103	126	103	126	0.96
4	8	0.0025	0.13	12.6	1.7	1	23	138	161	138	161	0.95
5	8	0.0066	0.36	11.2	1.0	1	23	233	255	233	255	0.97
6	8	8.5e-07	4.6e-05	23.5	1.2	1	23	261	283	261	283	0.96
7	8	2.7e-06	0.00015	21.9	0.8	1	23	290	313	290	313	0.96
8	8	0.72	39	4.8	8.6	1	23	320	343	320	343	0.86

Sequence Information

Coding Sequence: ATGCGGAAGTCATCGGCAAATGGCTGTGCAGCGAGTGCGAGCGACATCCAAGTGCTGGAACCACCGGCGGCTCCAGCAAACAAAGCAACCGATGTGGTTGATGACTCGAATTCCGATGAAAATCCCAGCCATCTGACGATTGCATGTCCGGAATGTGGCAAAATGTTTGCCGATCGGAGTGGCCTTCGTCGGCACGAATCGGTCCACACGAAGCATAAGCCGTACCTGTGCGAAAAATGTTCCCGTTCGTTTACGCAAAACACCAGCCTTGTGCGACACAGGCTCATTCATTTGCGCGAGAAAAACTTTCCCTGCACGCACTGTACGATGAAGTTCCGACAGAGGGTTAATCTGGACGCGCACGTCAAACAGGTGCATCCGCCAGCGGACGATCCGGAGTTGGAAAACCGGTTCCACTGCAAGAAGTGTCCGTCGGCGTTCAAAACGGCCGGTCGGTTAAGGGATCACCGGGCCCGACTGCACGGCGAGATGGTCATATTCGACCAGTGTGTGAAGCGCACGCCGAACGTAGCGAATGTAGCGCCCGACGGGTCAGAGGACAGTGATGAAACGTCCCAAGAGGAAGGTTCGCAATCGTCAGCACAGGACACGGAGCAGGAGGAAAGCGAGATAGTGCAGAAAGTAATCCCCAGTCGCCGGACCGAACATCTGAAGGGTAAAACGTCCCAGCGACGGCATGAGTGTGAGGTGTGCAAGGCAGCATTCCTGAAGAAGGCACACCTTGCCCAGCACATGGTGTCGCATCTCGGGTTTAAAGAGTTCCGGTGCGACGTTTGCGACAAAACGTTCTCCACCAAACAGTCGCTCAACAGCCACACCGCGCTGCACGCGCAAACCGAGTTGCCGTTCAGTTGCCAGGCCTGCGGGGAATCGTTCAGCCGTCGCGCTACGCTGAAAAGGCACCAGACCATGCTGCACGAGGAGCAGAAACATTCGTACCGGTGTCCTTACTGTGGGAAACGCTGTCGTTGGTATCACAACTGCCTTACGCACATCAAACGCTTTCATCCGAAGACGGACGGGAAGGAATTGTTGGATCCGATTAAAGAACCCGTCACGAACGGTGATCATGAGGAGACAGTCCCTTCGCCGGGAAATGAAAGTTAA
Protein Sequence: MRKSSANGCAASASDIQVLEPPAAPANKATDVVDDSNSDENPSHLTIACPECGKMFADRSGLRRHESVHTKHKPYLCEKCSRSFTQNTSLVRHRLIHLREKNFPCTHCTMKFRQRVNLDAHVKQVHPPADDPELENRFHCKKCPSAFKTAGRLRDHRARLHGEMVIFDQCVKRTPNVANVAPDGSEDSDETSQEEGSQSSAQDTEQEESEIVQKVIPSRRTEHLKGKTSQRRHECEVCKAAFLKKAHLAQHMVSHLGFKEFRCDVCDKTFSTKQSLNSHTALHAQTELPFSCQACGESFSRRATLKRHQTMLHEEQKHSYRCPYCGKRCRWYHNCLTHIKRFHPKTDGKELLDPIKEPVTNGDHEETVPSPGNES

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00095823;
90% Identity: iTF_00107162;
80% Identity: -