Basic Information

Insect: Anopheles melas
Gene Symbol: -
Assembly: GCA_000473525.2
Location: AXCO02007601.1:114-5002[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 3.1e-05 0.0017 18.5 1.7 1 23 272 294 272 294 0.97

2 15 0.0091 0.49 10.8 4.5 1 23 300 322 300 322 0.96

3 15 5.4e-05 0.0029 17.8 0.1 1 23 512 534 512 534 0.98

4 15 0.5 27 5.3 0.3 1 23 540 563 540 563 0.96

5 15 0.81 44 4.6 4.1 1 23 596 619 596 619 0.93

6 15 0.0034 0.18 12.1 0.0 2 23 705 726 704 726 0.94

7 15 0.0083 0.45 10.9 0.1 2 23 737 759 736 759 0.92

8 15 0.0039 0.21 11.9 0.9 2 19 767 784 766 785 0.95

9 15 0.0091 0.49 10.8 8.9 1 23 794 816 794 816 0.97

10 15 0.035 1.9 8.9 0.8 2 23 822 843 821 843 0.97

11 15 1.5e-06 7.9e-05 22.7 1.3 1 23 849 871 849 871 0.98

12 15 0.0012 0.067 13.5 0.2 1 23 877 899 877 899 0.97

13 15 3.3e-05 0.0018 18.5 0.1 1 23 905 927 905 928 0.95

14 15 0.055 3 8.3 0.1 1 23 942 964 942 964 0.97

15 15 2 1.1e+02 3.4 2.3 1 20 1579 1598 1579 1601 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	3.1e-05	0.0017	18.5	1.7	1	23	272	294	272	294	0.97
2	15	0.0091	0.49	10.8	4.5	1	23	300	322	300	322	0.96
3	15	5.4e-05	0.0029	17.8	0.1	1	23	512	534	512	534	0.98
4	15	0.5	27	5.3	0.3	1	23	540	563	540	563	0.96
5	15	0.81	44	4.6	4.1	1	23	596	619	596	619	0.93
6	15	0.0034	0.18	12.1	0.0	2	23	705	726	704	726	0.94
7	15	0.0083	0.45	10.9	0.1	2	23	737	759	736	759	0.92
8	15	0.0039	0.21	11.9	0.9	2	19	767	784	766	785	0.95
9	15	0.0091	0.49	10.8	8.9	1	23	794	816	794	816	0.97
10	15	0.035	1.9	8.9	0.8	2	23	822	843	821	843	0.97
11	15	1.5e-06	7.9e-05	22.7	1.3	1	23	849	871	849	871	0.98
12	15	0.0012	0.067	13.5	0.2	1	23	877	899	877	899	0.97
13	15	3.3e-05	0.0018	18.5	0.1	1	23	905	927	905	928	0.95
14	15	0.055	3	8.3	0.1	1	23	942	964	942	964	0.97
15	15	2	1.1e+02	3.4	2.3	1	20	1579	1598	1579	1601	0.92

Sequence Information

Coding Sequence: ATGAACCACAACAACCCATTGCCTCCGCTTTGGCAAGTGGCAACTACTACCGGCGGACACCAGCCGCGAATGAACAGCAGTGCCGGCAGCAGCACGAGCAAACTGACCGCCGGAAGCATTTCCTCTGTGAAGTACGTGTCCAATGCACGGCCTACCATGAAAATCATCAACATCCCCAACCAGCAGCAAGCGTCGATGACGGCCACGGCCACCAGCGATGGGACACTGCTTTACGGCACGTCCTTCGGAGGAGCCGGTTCGTATCTGACAGTGACGAACGACCAGCGGCAAATACAGCCGCCACCACAGGTACGCCGACCGGTGACAACCACCACTACCACCACCACCCATGCGGCACTGCTGAACGAATCCATCCTGCTGCAAACGCCGGACGGCCGGGAGTACCTCGTGGACGAACAGTCGATACAGAACATCGATCAGATACCGCCGGAAAACTTGATCTACATGACCGCTTCCGAAGCGCTGTCGGTGGTCGATGCCGATGACGTCGGCCAGCTCGCGATCGTAGACGAAAGTCAGCTCGCGCTGCACGATTACGTAGTGCAGGCGGAGGCGACGATCGATCAAACACAGCAGCAACTACAAGAGCCCGCCACCTCCGCCGAGGCACAACAGTACGCGGAAGAGTGCGAGGTGACGGAGGAAGTGATTACGGACGATTGGGTGCAGCCGCAGGGCGAAGAGTGCGTGCAGGTGACGGTCGACCAGCTCGGTGTGAGTGCGGTCGTGGTACAGGAGGAGGACGACATTTCCGTCCCGCTCGACCAGGACCAGTACACGCTGTCGCGCCCGTACCCGTGCGATTTCTGCAGCCGGCGGTTCCGCAAGAAGAGCAGCCTGCAGAACCATCTGATGGCGCACTCGAACGATCGGCCGCACTGTTGCAACCTGTGCGGGGCACAGTACAGCCACCGGGCGGATCTGATCAACCATCTGAAGCAGCACGCGTACTCCGTGGCGGAGCAGGACGAGCTGGCGCTGCGCAGTGACCAGGAAGCGGAATATGATCTGCCCGATCTGGGGCACACATCCTCCGGCGGTGGCGGCCATAGCATGAAGCATCGGTTGCGGCATTCAAGCGACGACGAAGACATGTACATCCAGAACTCGATGGTGAGCTACAACTCGCAACCACCGATGCAGCTGATTTCCACCACGCATTACGGTGCTTCTACCTCGTCGACGATCGGCTCTTCCTCGTACGCGCATGAGGTACCGATGGAGCAGCCACCTTACCTCGAGAGCGTTCCTCCCGTATTGGAGCAAAAGTACGCGCTCGGCAAAATGGATCCGGCCGGCCCGGCAACACTTTCCACCACCGGCAAACGTACGCCGCGGAAAAAGCAATCCCAATCCACCCAGGTTACGCGCACGGCACGGACAAAGCCAGTGTTTGTCTCGAAAGTCGGCAGTCGGCAGATTAAAAAAGAACCCCTGGATCATGGGGAAGGTGGTAACGCCATATCATCGCCACCTCCCACGAGGACGGTCGCAGCGGACTGGCGCAAACCGTTCGTCTGTCAGCAGTGTGGCGCATCGTTCGCGCGAGAGAAAGCGCTCCTTTCGCACGCCCGCACCCATGCCGGCAGCACGCGCTACGATTGCGCATTGTGTAATGCGCACTTTTGGGAGCAGTCGCTGCTGCGGGACCACGTGCAGCGGGCGCACCCGTCGCAGGAAGCCTGGGTGGCCGACCATGAGCCTTACGGCGGTGAGCACGGAGCGATAGAGCTGCCGGTGGAGACCACCCCCACCACCAAGCAGTACAATTGTGATAGCTGCAGTGCAGCTTTCTTCCAGCTGGACCATCTACTGAACCATACGCACCACGCGCACGGTACCTTCGAGCAGCATCAGCAACCGAGCTCTAACCGTAGTGTGCTGGTAAAGCAGGAACTGCTGCAAACCTCCAGCAAAGTGGAGCTGGAAAGTGACCGTGAAGCGGAAGCCACCGACCAGGAAGCGGTCGAGGAGGACGAGGAAGAGGAGGGCGAAGAGTACGACAATCTCGAGTACACGATCGAACACTACGAGCAGCAGGAGCCGCCGCCGCCGCCGCAGCGTTCGAACGAACCCGACCAGTCCGCGCTGACGTGTCGCGATTGTGGGGAGTCGTTCGACAGCGCGATGGATTTGCTCGACCACAGTGAGGTGCACGGTGGTGGCGCCGCCCAGTACGAACCGCTCGAGTGTCAGCTGTGCGGGGAGAAGTTCCCGGACGAGGCCAACATCAAGCAGCACGTGCAGGACCGGCACCGCGACGAGCTGACCGCAACGTCGTGCGCGATCTGCGGCAAGCGCTGCAAAAGCCAAACCACGCTGATGAAGCACGCGTGGGACCATTCGCGCGAGCGGGCCCACTCCTGCTCGAAGTGCGGCAAAACGTTCCACCACATGACGCGGCTGAAGCGGCACATGGACTCGCACCGCAACAAGGCGGTCCGGTGTGAGGTGTGCAAGGAAGAGTTCCCGGACGGCCGGACCCTGATGAACCATCGCCATTCGCACACGAAATCGAACGAGTATCCGTGCCACGAGTGTGGCAAAACGTTCGGTTCGCGCTCGTCGCAGCAGATCCACATGCGTATCCACACGGGGGAGCGGCCGTACGCGTGCCGGTTCTGCTGGAAAGCGTTCGCCGACGGGGGCACACTGCGCAAGCACGAGCGCATCCACACGGGGGAGAAACCGTACGCGTGCCCCGTCTGCCCGAAAGCGTTCAATCAGCGCGTGGTGCTGCGCGAACACATCCGGGCGCATCATTCGCAGGCCGACGCGAAGCGCGGCTCGCCGGACCAGCCGTACTACTGCACGGTTTGCAGCTCACCGTTCGGCACGACCGCCGATCTGGTGCAGCATCTGATCGAGCACAGTGACACGAACACGGCGATGAAGCGCAAACCGCCCACCTTCCCGCGCAAGTACAAGCGGCGCCGGAAGCTGAAACCGCACGAGCTCGAGCGGCTGCAGAGCGGCCGGCGGAAGCAGAAATCCAAGCGCCAGATGGACAATGAGGAGGAGGAGGAGGAAGAGGAGGAGGACGACGACGATGCGAGTGGGGGTAGTGGGAATCAATTCGAGGACGGTACGACAGCGCACTCAACGGATCGCACGGTGGAACGGGCGGGCGGCGATGTTAAACCAACCGGCTCCTCGTTCGTTCGCTACCATCCGGACGGGACGCGCAAAGCAAGCACGCGCGAAATGTACCTTGAGTATGACGACATGGGAGGAGGGAGCGCCACGCATGCTCCCAAGGCATCCTCGCAAGGTATGCTGGACGTCAATGGGATCAATCTGCTGAGCAATGTGGTGCTGCTGCACGGACAGCAGGAAGAGCCGTCCAACGCGCACAACAACAACCATCTGCCCGAATCTCCTCCCCAGCACGCGTTCGGGGAGTTGCCCAAAGCGAAGCAGCACCAGCAGCAGCAGCCACCGGGAAGTTCGCGCATGATTTACACCCAAAAATCAACCACAAAAGCAGCCCCTGTGTCGTCCCGCAAAACGCCATCCACCCGGAAACGGCCCGCCGCCAAAGAGCAACGCCCGGCGGCAGCGCCACCGCCGCCGGTGAAGCTGGAACCCGACGAGGATGATCCTGCCATCGCGATGGAAGCGTTGTTCCGCGGGCGCAAACGAAACGCTTCACTGCTGCCCGAGATCCCGCCGCACCGGATCTCGTCCGTCGGCTTTCCGCTGCTGGACGATGGCAACACGGACGACCCGATGGACGAGCCGGAGCAGCGGGCGCGCCGCAGTACCACCTCGTTCAGCGCCTCGGAGGACGATCTGCTCAGCCAGCAGCTGCTGATGGAGATTTCGCACAAGAGCAAGTACACCGAGCGGTTCAACAGCGACACGCTGAACGATCTGGAGGAAATACTCCGCTCGCCCGTCAAGGGGCCCGGATCGCCGGCCGTGACCAAACGTGCCACGACCGTCGCCTCCACCAGTGCTACCAGCAAGAAGCAACAGCAAAGTGCTGCTGCCGCTAAAAAGCCAACCAGCCAGCGTAAGCGAACGGCAGCACCGAAAGCAAAGGCTGCGGCGAAGGCGAATAATAAACGAGCTGCTTCCTCCACTGCCAGTGGCGCCGATTCCTCCAGCAGCAGGCAGCCACCAAAGCCAGTGGAAAAGCGGGCGGCCCGGGAACCGCCGGCAGTGTTGCGCAGTCAGCGGCTTACGCGCCGCCAGCTCGAGCGTGAGGTGAACTTTCTCAAGGAAGCGTATGACGCCGGTGAACCGGTGCACGAGACAACGGCTGACGGGTCCGGTGGCTCATCGTCCGTGGCGGTGGTAAAGACAGAAGCGGTCGATAAACGCTTCTTGCTGGATGGCACTGCGACCGGTGTGGCTGAGACGCTGGACCGACCGGACAGTTCCGAACGCTTGGCAGCGATGCTGCTGAACGATGGCCTTCCGGACGAATCGGACAGCAGCAGCAGCAGCGGTGAGGGAAGTCGCCGTAGCAGTGTGATGTCCACCGCAGCGCGACAGACGCATAAGTACGGTCCGGAATCGTACGCAGAAGGATTGCAGATGATGGAAACGGCAGAGGACGAACATGTGGTAAAGCAGGAGGATGACCAAGGGCAGGGTGAGCATCACTACGAGCTGGGTGACGACGATGTGGGTGAACTGTATCTGGATGATAATGACACTACTACCTCAGCAACAACACCAGCCACAGCCATCGGCGACGAACCGTTGCATCGATGTTCGATCTGTTGCGCCTGCTTTGATGATCGGGCTCAGCTCATCCTGCACGTTCCGGTGCATATTTAG
Protein Sequence: MNHNNPLPPLWQVATTTGGHQPRMNSSAGSSTSKLTAGSISSVKYVSNARPTMKIINIPNQQQASMTATATSDGTLLYGTSFGGAGSYLTVTNDQRQIQPPPQVRRPVTTTTTTTTHAALLNESILLQTPDGREYLVDEQSIQNIDQIPPENLIYMTASEALSVVDADDVGQLAIVDESQLALHDYVVQAEATIDQTQQQLQEPATSAEAQQYAEECEVTEEVITDDWVQPQGEECVQVTVDQLGVSAVVVQEEDDISVPLDQDQYTLSRPYPCDFCSRRFRKKSSLQNHLMAHSNDRPHCCNLCGAQYSHRADLINHLKQHAYSVAEQDELALRSDQEAEYDLPDLGHTSSGGGGHSMKHRLRHSSDDEDMYIQNSMVSYNSQPPMQLISTTHYGASTSSTIGSSSYAHEVPMEQPPYLESVPPVLEQKYALGKMDPAGPATLSTTGKRTPRKKQSQSTQVTRTARTKPVFVSKVGSRQIKKEPLDHGEGGNAISSPPPTRTVAADWRKPFVCQQCGASFAREKALLSHARTHAGSTRYDCALCNAHFWEQSLLRDHVQRAHPSQEAWVADHEPYGGEHGAIELPVETTPTTKQYNCDSCSAAFFQLDHLLNHTHHAHGTFEQHQQPSSNRSVLVKQELLQTSSKVELESDREAEATDQEAVEEDEEEEGEEYDNLEYTIEHYEQQEPPPPPQRSNEPDQSALTCRDCGESFDSAMDLLDHSEVHGGGAAQYEPLECQLCGEKFPDEANIKQHVQDRHRDELTATSCAICGKRCKSQTTLMKHAWDHSRERAHSCSKCGKTFHHMTRLKRHMDSHRNKAVRCEVCKEEFPDGRTLMNHRHSHTKSNEYPCHECGKTFGSRSSQQIHMRIHTGERPYACRFCWKAFADGGTLRKHERIHTGEKPYACPVCPKAFNQRVVLREHIRAHHSQADAKRGSPDQPYYCTVCSSPFGTTADLVQHLIEHSDTNTAMKRKPPTFPRKYKRRRKLKPHELERLQSGRRKQKSKRQMDNEEEEEEEEEDDDDASGGSGNQFEDGTTAHSTDRTVERAGGDVKPTGSSFVRYHPDGTRKASTREMYLEYDDMGGGSATHAPKASSQGMLDVNGINLLSNVVLLHGQQEEPSNAHNNNHLPESPPQHAFGELPKAKQHQQQQPPGSSRMIYTQKSTTKAAPVSSRKTPSTRKRPAAKEQRPAAAPPPPVKLEPDEDDPAIAMEALFRGRKRNASLLPEIPPHRISSVGFPLLDDGNTDDPMDEPEQRARRSTTSFSASEDDLLSQQLLMEISHKSKYTERFNSDTLNDLEEILRSPVKGPGSPAVTKRATTVASTSATSKKQQQSAAAAKKPTSQRKRTAAPKAKAAAKANNKRAASSTASGADSSSSRQPPKPVEKRAAREPPAVLRSQRLTRRQLEREVNFLKEAYDAGEPVHETTADGSGGSSSVAVVKTEAVDKRFLLDGTATGVAETLDRPDSSERLAAMLLNDGLPDESDSSSSSGEGSRRSSVMSTAARQTHKYGPESYAEGLQMMETAEDEHVVKQEDDQGQGEHHYELGDDDVGELYLDDNDTTTSATTPATAIGDEPLHRCSICCACFDDRAQLILHVPVHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00101120;
90% Identity: iTF_00101120;
80% Identity: -