Basic Information

Insect: Anopheles melas
Gene Symbol: -
Assembly: GCA_000473525.2
Location: AXCO02005156.1:16562-18946[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 2e-06 0.00011 22.3 3.0 1 23 109 131 109 131 0.98

2 7 2.2e-06 0.00012 22.1 5.4 1 23 137 159 137 159 0.98

3 7 6.6e-07 3.5e-05 23.8 0.5 1 23 165 187 165 187 0.98

4 7 1.8e-06 9.9e-05 22.4 0.2 1 23 193 215 193 215 0.97

5 7 1.5e-07 8e-06 25.8 3.4 1 23 221 243 221 243 0.99

6 7 7.6e-05 0.0041 17.3 0.6 3 23 251 271 249 272 0.94

7 7 1.9e-05 0.001 19.2 0.8 1 21 278 298 278 299 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	2e-06	0.00011	22.3	3.0	1	23	109	131	109	131	0.98
2	7	2.2e-06	0.00012	22.1	5.4	1	23	137	159	137	159	0.98
3	7	6.6e-07	3.5e-05	23.8	0.5	1	23	165	187	165	187	0.98
4	7	1.8e-06	9.9e-05	22.4	0.2	1	23	193	215	193	215	0.97
5	7	1.5e-07	8e-06	25.8	3.4	1	23	221	243	221	243	0.99
6	7	7.6e-05	0.0041	17.3	0.6	3	23	251	271	249	272	0.94
7	7	1.9e-05	0.001	19.2	0.8	1	21	278	298	278	299	0.95

Sequence Information

Coding Sequence: ATGAATTTCTTCATACCGAACGAGGTGAAACGGGAAGGTATTTACCTTCAGCATCAGCTTGGCCCTCCGCTGATACACCAGCAGCACCACCAACTGCCCCAGCAGTCGCAGCATCAGCTGCTCGGCAAAGCGAACCGGAACATCGTCATCCCGCAGCTGCCGGAAGGGTTCATCGTGAAGGTGAAGGAAGAGTACACAGAAAACTACGTCCGCACCGTGACGAAAATCCCGGAAGTATGGTGGAACCAGGAGCAGTTTATCCGCACGGTCAAGTCGCCCGGTAAGAAGGAGCGAAAGTACCACGATTATAACGCGGTCAGCGAGCACCAGTGCGATGTGTGCGGGAAGTATTTCAAGGATAAGTACAAGCTGAACTACCACGTGCGCATCCACGTGCCGGAACTGTCGCACCGGTGCGACGTTTGCGGCAAGGTGTTTGCGCACCAGTCGACGCTGCATAATCACAAGCGCATCCATACAGGTGAGCGTGCGTTCAAATGTCTAACCTGCGGCAAAGCGTTCGTACAATCGTCGGCCCTGTCGAACCACACGAAGATACACACCGGCGAGCGGCCGCACGAGTGCCTGATCTGTGGCATCAGCTTCATCCAGAAGATCAACCTTATCTACCACATCCGCATACACAACGGCGAGCGTCCGTACCGGTGCAACATCTGCCAGAAGTCGTTCATCCAGCAGAGCCATATAAAGAACCATATGAAGGTGCACAAGAAGGACAATCCGCTCGACTGCAGCATGTGCGGCAAAAACTACAGCGATCTCAATGAGCTGACCGAGCACTACGCGTCGCACCATACGGCCGAGCTGACGTACCGGTGCCAGGCCTGCGGCAAATCGTTCGCCCAAGCCAACCATCTCAAGATCCACAAGAAGAACTTCTGCAACAGCAAGTCGAACTAG
Protein Sequence: MNFFIPNEVKREGIYLQHQLGPPLIHQQHHQLPQQSQHQLLGKANRNIVIPQLPEGFIVKVKEEYTENYVRTVTKIPEVWWNQEQFIRTVKSPGKKERKYHDYNAVSEHQCDVCGKYFKDKYKLNYHVRIHVPELSHRCDVCGKVFAHQSTLHNHKRIHTGERAFKCLTCGKAFVQSSALSNHTKIHTGERPHECLICGISFIQKINLIYHIRIHNGERPYRCNICQKSFIQQSHIKNHMKVHKKDNPLDCSMCGKNYSDLNELTEHYASHHTAELTYRCQACGKSFAQANHLKIHKKNFCNSKSN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00102524;
90% Identity: iTF_00102524;
80% Identity: -