Basic Information

Insect: Anopheles melas
Gene Symbol: -
Assembly: GCA_000473525.2
Location: AXCO02008084.1:11940-14099[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 1.3 72 4.0 5.9 2 23 250 272 249 272 0.92

2 14 0.00026 0.014 15.6 0.4 2 21 291 310 290 311 0.94

3 14 0.00059 0.032 14.5 2.1 1 21 316 336 316 338 0.94

4 14 0.23 13 6.3 0.6 1 23 344 367 344 367 0.93

5 14 0.0056 0.3 11.4 1.0 1 21 379 399 379 400 0.95

6 14 0.0063 0.34 11.3 0.7 1 23 404 427 404 427 0.96

7 14 0.0094 0.51 10.7 0.2 3 23 439 460 437 460 0.91

8 14 0.0065 0.35 11.2 0.9 1 21 477 497 477 498 0.94

9 14 1.2e-05 0.00067 19.8 0.7 1 23 505 527 505 527 0.98

10 14 6.5e-05 0.0035 17.5 2.7 1 23 533 555 533 555 0.98

11 14 2.1e-06 0.00011 22.2 0.3 2 23 563 584 562 584 0.96

12 14 8.8e-05 0.0047 17.1 1.4 1 23 590 612 590 612 0.98

13 14 2e-07 1.1e-05 25.5 1.2 1 23 618 640 618 640 0.98

14 14 1.2e-05 0.00063 19.9 1.8 1 23 649 672 649 672 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	1.3	72	4.0	5.9	2	23	250	272	249	272	0.92
2	14	0.00026	0.014	15.6	0.4	2	21	291	310	290	311	0.94
3	14	0.00059	0.032	14.5	2.1	1	21	316	336	316	338	0.94
4	14	0.23	13	6.3	0.6	1	23	344	367	344	367	0.93
5	14	0.0056	0.3	11.4	1.0	1	21	379	399	379	400	0.95
6	14	0.0063	0.34	11.3	0.7	1	23	404	427	404	427	0.96
7	14	0.0094	0.51	10.7	0.2	3	23	439	460	437	460	0.91
8	14	0.0065	0.35	11.2	0.9	1	21	477	497	477	498	0.94
9	14	1.2e-05	0.00067	19.8	0.7	1	23	505	527	505	527	0.98
10	14	6.5e-05	0.0035	17.5	2.7	1	23	533	555	533	555	0.98
11	14	2.1e-06	0.00011	22.2	0.3	2	23	563	584	562	584	0.96
12	14	8.8e-05	0.0047	17.1	1.4	1	23	590	612	590	612	0.98
13	14	2e-07	1.1e-05	25.5	1.2	1	23	618	640	618	640	0.98
14	14	1.2e-05	0.00063	19.9	1.8	1	23	649	672	649	672	0.98

Sequence Information

Coding Sequence: ATGGACCACATCCTGATCGAGCCGGACTGCTACAAGGTGTGCCGGATCTGCATGGAAAGCTGCGAGGACGACTGTGTGTGCGTGTACGACGAGTTCGAGGATGTGCTGCTGAGCGACGTAATCCGGGAGTGTGCCCGGGTCGAGATTCGCAAGAACGATGCGCTGCCTCGCAACGCTTGCCGGAACTGTGCCGAGTATCTGATCATCTCGTACCACATCATACAGAAGTGTCGCGATTCAGACGTGACGCTACGGTCCATCTTTAAGCACGAGCTAAACTTGCACCGCGAAGAGCGCAAACCGAACGCGTCGTCGGTGGTCGGGTTGCGTACGGACGATATGGACCCGTCCGGCTACGAGTTCCTGCTAGCGAACGGGTACGACACCATGATGCTGGAGGGTGAAGGTATGCTGCTGGAGAATGCGGACTGCGACTTTACCGCACCAAGCGGTGAGAAGGCTGACAGCGTTCAGGAGGAAGGTTTCGCCGACACGGCTATCGAGCAGCAGCAGCAACCACTGTCCGGCATGGAACAATCGCACCAAGAATATCAGCATTCTGAGTTAACCCCCCAACAACCGGAACTGGAAGACGAGCAAAACAAACCGGTACTGTCAAGCGAAGATATCGAGCTGATTCTGGAGTACGAAGAAAAGGCACTTGCAGCGCGTCGCCTGGTTACGGGTGAAACGGTTCACGAGTCGAGCGAAACCACCGAAGAGGACGGTTTATGCAACGAGCAGAAGAAGTGTTGCGGCTGCCGGAAGCTGTTCAGCAGCGAACAAAGCTTACGGGAGCACTGCCAAACGGTCCACCTGCCGGTGGAATCGTCCGCATCGGATGGACCGGCCAGCGAGAGTAAACCAATCCGCTGCCCGGTGTGCTTTAAACGGTTTAGCTCACGCCAGTTGCTGAAAGAGCACGAACGCTCCGTCAACCGGAAGTATGTGTGTGCGCAGTGCGGCAAGCGTTTCATGACGCAAGCCAACCTGGACACCCACACCAAATGCCACAAGAACAAGGAAACGTACAAATGTTGCGGCTGCCGGATAGATTTCGAGCAGGAGCTGGATCTGCTCGTACACTCGCAAAACGTGCACCGGCTGGAGCGATCGGTCGATCCGGACAAACCGTTCGAGTGTGACACGTGCTATCGGCGCTACCCGACGCGCAAATCGCTCGCCACCCACAAACGCCAGATCCGCCAGTTCCAGTGCCCGCTGTGCGGTGCCATGTTTATGAAGCAGCTGTTCCTGCAGCTGCACCACGAGCGCGCTCACCAGCAGGAGGCGCAGGAGAAGCGCCGCCGGTGCTGTGGCGGGTGCCGCGAGGTGTTCGAGAATGCGGCCGCCCTGCGCGCCCACTCCGAGCGGGTGCACAAACCGGCCGACGGGTCGGCCGGCTCCGGCACGGACGATGGCAAACCGTTCGAGTGTAACGTGTGCCGGAAGCGGTTCGCGTCGATCTTTTTCCTACTTCAGCATCAGCAGAAGGTGGCGCGCGAAAAGTGCTACCCGTGCACCGTGTGTGGCCGCACGTTTGGGCGTGCGCACGATCTGTCCAACCACGAGACGACCCACTCGAACGAGATGCCGTTTGAGTGTAGCGTTTGCAGCAGGCGGTTCAAGAACAAGCTGTACCTGAAGAACCATCTTAAGCTGCACGCGAGCAGCGCCAAGGAGCAGGTGTGCGTCGAGTGCGGCAAAGCGTTTCGCACGAAGGATCTGCTCAAGACGCACCTCATCAGCCACTCGCAGGTGCGCAAGTACGCTTGCACCGTGTGTCCGGCGACGTTCAAGCGGTTGCAGTGTTTGAAAATTCACACCCGCGTACATACGCGCGAGAAAGCGTTCGAATGTGCGGTTTGTCGCAAGCGGTACGTACAATCGTCGGATTTGAAGCGACACATGCGCACGCACAATCCGGGCGACGAGGGGAAACCGTTCCAGTGTGAGTACTGTTTGAGGCGCTACCCGCGCAAGGACTATCTGAAGGTGCACATTCGCAAGCAGCATCTGGAAAAGACGGCGGAGCATCATCACCAGCAGGAAGGGATGCACGCAGCGGAAGCAGTCGGCGGCATCGGTAGCGACGATGGGAATGGATCGTTCGAACGCAACGATCCACCGAATGAGATGAGCGATTTCATGGACTGTTGA
Protein Sequence: MDHILIEPDCYKVCRICMESCEDDCVCVYDEFEDVLLSDVIRECARVEIRKNDALPRNACRNCAEYLIISYHIIQKCRDSDVTLRSIFKHELNLHREERKPNASSVVGLRTDDMDPSGYEFLLANGYDTMMLEGEGMLLENADCDFTAPSGEKADSVQEEGFADTAIEQQQQPLSGMEQSHQEYQHSELTPQQPELEDEQNKPVLSSEDIELILEYEEKALAARRLVTGETVHESSETTEEDGLCNEQKKCCGCRKLFSSEQSLREHCQTVHLPVESSASDGPASESKPIRCPVCFKRFSSRQLLKEHERSVNRKYVCAQCGKRFMTQANLDTHTKCHKNKETYKCCGCRIDFEQELDLLVHSQNVHRLERSVDPDKPFECDTCYRRYPTRKSLATHKRQIRQFQCPLCGAMFMKQLFLQLHHERAHQQEAQEKRRRCCGGCREVFENAAALRAHSERVHKPADGSAGSGTDDGKPFECNVCRKRFASIFFLLQHQQKVAREKCYPCTVCGRTFGRAHDLSNHETTHSNEMPFECSVCSRRFKNKLYLKNHLKLHASSAKEQVCVECGKAFRTKDLLKTHLISHSQVRKYACTVCPATFKRLQCLKIHTRVHTREKAFECAVCRKRYVQSSDLKRHMRTHNPGDEGKPFQCEYCLRRYPRKDYLKVHIRKQHLEKTAEHHHQQEGMHAAEAVGGIGSDDGNGSFERNDPPNEMSDFMDC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00095209;
90% Identity: iTF_00107131;
80% Identity: -