Basic Information

Insect: Anopheles melas
Gene Symbol: -
Assembly: GCA_000473525.2
Location: AXCO02016550.1:2699-5223[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 5e-06 0.00027 21.0 2.7 1 23 156 178 156 178 0.99

2 15 0.00041 0.022 15.0 4.9 1 23 189 211 189 211 0.96

3 15 9.1e-06 0.00049 20.2 0.5 2 23 221 242 219 242 0.92

4 15 3.3e-06 0.00018 21.6 3.8 1 23 248 270 248 270 0.99

5 15 0.018 0.96 9.9 0.1 2 23 278 299 277 299 0.97

6 15 8.7e-05 0.0047 17.1 3.4 1 23 305 328 305 328 0.94

7 15 0.0035 0.19 12.1 5.4 1 21 334 354 334 355 0.94

8 15 0.32 17 5.9 4.7 3 23 363 384 361 384 0.91

9 15 6e-05 0.0032 17.6 0.5 1 23 431 453 431 453 0.97

10 15 0.00012 0.0067 16.6 0.2 1 23 464 486 464 486 0.97

11 15 0.00012 0.0062 16.7 1.7 1 23 511 533 511 533 0.99

12 15 0.34 18 5.8 2.5 2 23 569 590 568 590 0.94

13 15 0.00069 0.037 14.3 5.0 1 23 596 618 596 618 0.98

14 15 4e-07 2.2e-05 24.5 1.5 1 23 626 648 626 648 0.99

15 15 0.00046 0.025 14.8 0.7 1 23 654 677 654 677 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	5e-06	0.00027	21.0	2.7	1	23	156	178	156	178	0.99
2	15	0.00041	0.022	15.0	4.9	1	23	189	211	189	211	0.96
3	15	9.1e-06	0.00049	20.2	0.5	2	23	221	242	219	242	0.92
4	15	3.3e-06	0.00018	21.6	3.8	1	23	248	270	248	270	0.99
5	15	0.018	0.96	9.9	0.1	2	23	278	299	277	299	0.97
6	15	8.7e-05	0.0047	17.1	3.4	1	23	305	328	305	328	0.94
7	15	0.0035	0.19	12.1	5.4	1	21	334	354	334	355	0.94
8	15	0.32	17	5.9	4.7	3	23	363	384	361	384	0.91
9	15	6e-05	0.0032	17.6	0.5	1	23	431	453	431	453	0.97
10	15	0.00012	0.0067	16.6	0.2	1	23	464	486	464	486	0.97
11	15	0.00012	0.0062	16.7	1.7	1	23	511	533	511	533	0.99
12	15	0.34	18	5.8	2.5	2	23	569	590	568	590	0.94
13	15	0.00069	0.037	14.3	5.0	1	23	596	618	596	618	0.98
14	15	4e-07	2.2e-05	24.5	1.5	1	23	626	648	626	648	0.99
15	15	0.00046	0.025	14.8	0.7	1	23	654	677	654	677	0.96

Sequence Information

Coding Sequence: ATGGAATACAACAACACCTACAACAAACCGTATTGTGGCATATCGCAGCCGACCATACCACCAGCAGCAGCAGCAGCAGCAGTCCCAGGCAGCTCCGGGTTCTTCCCGGCCAATGATACCGCACCGTCATCGTTCCTTAAAGTGCCCAATCCACCGTACATCAAGCAGGAGACGGTCCCGGTGGGCGGAGAATCGGTTATCCCGGGTGGAACGGTAACACCGCCCGTCAACTACAGCCAGGATCATCATCAGTATGGACCGGCGGGTAGTTACGGTGAACCGGGCGATGTAGAGAAGCCACCACTGTTCTATCGCAAAGCGTTCGACATGCCGTACATGGCGACGCCTGAAACTGGTTCCCCGCTGCCTGCCTCATACCCGACCGCCTCGCCAGTTGCTCCACCAGCAGCAACACCTTCCTCGTACACCCCCCTGTGTGAGCCGCCGGACAGCAGCAACGTACGCTTCAAGTGTGAAACCTGTCCGAAATCGTTCGACACGAGGCAGAAGCTGGAAAAGCACAACCGCACCCACCAGCCGAACGGGGGTGCGGCCGGGCTCGAGTTTAAATGCCGCATGTGCGACAAAACGTTCCGCACGAAGAGTACGCTCATCTGCCACGAGAAGGTGCACGGCGAGAGTGGCCTAGGCAGCAGCTGCCCCTGCGTCGAGTGCGGCAAGGTGTTTGCGACGGAGGAAAAGCTACAGGTGCACCGGCGGCTGCACACGGGCGAAAAACCGTACCAGTGCAAGGTGTGCCTGAAGTGCTTCAACCACCAATCGAACCTGATCGTTCACGCGCGCATCCACGACAAGGTGAAGCAGGCGCTCAAGTGTGCCCGGTGCAGCAAGGTGCTGGACAGCGAGGAGCGACTCGCCGTCCATATGCGGCTGCACACGGGCGAAAAGCCGTACAAGTGTTCGTACTGCGACAAGCGCTTCAATCACAAGAGCACGGTCAGCACGCACGAGAAGGCGGCCCACATTGCGGCCAACTCGTACCGGTGTGGCCGCTGCCACAAGACGTTCAACCAGAAGTGCCAGCTGCAGTACCACGAGAAGCTGCAGGAGGAGCACACGATCGCGTGCGAGCACTGTGAGAAGGTGTTTTGCTACAAGGCGAGCCACAAGGAGCACCTGTTTAAGGTGCACTTTCCCCGGCCGAAAAAGAAAACGCAGCGGAAGGGAGGGAGTCTGCGGGAAGGAGCTGAGCAGCAGCAGGAATCGGGCACCGGTGGTGATGGTGCAATGGCAGGGAGCAACGACGGGGGTAATCAGGGCCGGAACAAGTTCAAATGTACCGTGTGCGATCGTCGGTTTTACTACGAGCGGGCGCTCGAGATGCACATGGGCGTGCACGATGCGTCGCTGGACGTGAACGTGCTGTACTTTTCCTGCGACTACTGTCCGGAAACGTTCACCGAGGAGGAGACGCTGCAGCAGCACGAGGCCCGCCACGTGGCCGACGGGACGACCGATTTCCGCGCAAACATGAAACGGGCCGAGGAAGGGGGAAACGCCACCACCGGGTACAGGTGTCCGCTGTGCTTTAAGCAGTTTGAGGATGAGCCGTCCTTACGCGAACATCACCGTTCGCACCTGTGCCCATTTCCCGACTGTGCGCGGTGCGACCCAGTACGGCGCGATGATGCGTTCGACCTGACGCGCAGTACGTACGATCCGGCGGACGATACGCAACCGACGGAGTGTAACGTGTGCCATCGCGTACTGCCAACGTTCGAGGCGTACCAGAACCACTTCCACTACCATACGTCGCGCGTCCCGTTCTACTGCTACCACTGCCGGGAGGAGTTTAACGACAAGCGGGAGCTGTACAACCACACGCGGACGCATGCGCCGCGCGCACCGGAATCGTACACGTGCGAGGTGTGCGCGAAGGTGTTCTCGACCAAGGGGAACTTTAAGCGGCATTTGAAATCTCACGAAGCGGTCCGGGCGTTCGCGTGCGATCGCTGCTCGAAGCAGTACGACTACAAGAGTGCGCTCGAGGTGCATCTGAAGCGTTCGCACGGTATTGAGCTGTGA
Protein Sequence: MEYNNTYNKPYCGISQPTIPPAAAAAAVPGSSGFFPANDTAPSSFLKVPNPPYIKQETVPVGGESVIPGGTVTPPVNYSQDHHQYGPAGSYGEPGDVEKPPLFYRKAFDMPYMATPETGSPLPASYPTASPVAPPAATPSSYTPLCEPPDSSNVRFKCETCPKSFDTRQKLEKHNRTHQPNGGAAGLEFKCRMCDKTFRTKSTLICHEKVHGESGLGSSCPCVECGKVFATEEKLQVHRRLHTGEKPYQCKVCLKCFNHQSNLIVHARIHDKVKQALKCARCSKVLDSEERLAVHMRLHTGEKPYKCSYCDKRFNHKSTVSTHEKAAHIAANSYRCGRCHKTFNQKCQLQYHEKLQEEHTIACEHCEKVFCYKASHKEHLFKVHFPRPKKKTQRKGGSLREGAEQQQESGTGGDGAMAGSNDGGNQGRNKFKCTVCDRRFYYERALEMHMGVHDASLDVNVLYFSCDYCPETFTEEETLQQHEARHVADGTTDFRANMKRAEEGGNATTGYRCPLCFKQFEDEPSLREHHRSHLCPFPDCARCDPVRRDDAFDLTRSTYDPADDTQPTECNVCHRVLPTFEAYQNHFHYHTSRVPFYCYHCREEFNDKRELYNHTRTHAPRAPESYTCEVCAKVFSTKGNFKRHLKSHEAVRAFACDRCSKQYDYKSALEVHLKRSHGIEL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00104534;
90% Identity: iTF_00107123; iTF_00104534;
80% Identity: -