Amac011047.1
Basic Information
- Insect
- Anopheles maculipalpis
- Gene Symbol
- topi_1
- Assembly
- GCA_943734865.1
- Location
- CALSEK010000195.1:139636-141048[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.0025 0.14 12.5 4.2 1 23 45 68 45 68 0.96 2 11 0.0072 0.38 11.1 0.1 2 20 105 123 104 125 0.92 3 11 0.061 3.3 8.2 2.9 2 23 160 181 159 181 0.94 4 11 6.8 3.6e+02 1.8 0.1 1 10 187 196 187 207 0.78 5 11 0.67 36 4.9 3.5 1 23 227 250 227 251 0.94 6 11 0.17 9.1 6.8 3.8 2 23 273 295 272 295 0.91 7 11 1.3e-06 6.9e-05 22.9 3.2 1 23 328 350 328 350 0.95 8 11 0.00084 0.045 14.1 1.4 1 23 356 381 356 381 0.96 9 11 0.21 11 6.5 1.5 1 23 387 409 387 409 0.88 10 11 6.8e-07 3.6e-05 23.8 1.9 1 23 415 437 415 437 0.96 11 11 0.00011 0.0058 16.9 3.4 1 23 443 466 443 466 0.97
Sequence Information
- Coding Sequence
- ATGGGTCGGATAAAGAAAATTGAAGTTAGCCAAGTCACACAAACGCTTGGAAAGAATACTCAACAATGGCAAAACGTGCTGCAACAATCTGGCCCCTCGAAAAGTAAAGCGAAAGCTGCGAACAGGAAGAAGTTTAACTGCCAACACTGCAAGCGTAAGTTCGTCTATCTGACTGGGCTCGCCCGCCATGAGAAAAAATTTCATCCGGAAAAAGAAAAATCCTCGAACCCGGGCACCGAACAAACCGAGAAGGAGGCAGCAACAGGTGCTGTATCAAACACACCCCCAACAACCACATTCGAAATTGTGGTGAAATGTAAAAATTGTGGTGAAATTTTTCCCGATGCTGAGCGCTTTGAAGCTCACACTAGCCGGCTCAGCTGGGAGCAGTTGTTCGGGAACCAGCCGGAGGAGCAGGATGAAAAGGTGTCGCTGTTTCTGGCTCAGCTTTTCATCGTCGTTATTCATATGGCTCTACAGTGCGAGTTTTGCGATGCACACTTCTCGGATTTTGCGTCCCTGTTCTATCACGAATCACATCACTCACCTTACGCCGGTTACTCGTGTACGTTCTGCAAGCTTAACTTTCTCACGCTAGAAGCGGTACTGGATCATCGGGAACAGTGCCAGGAGTACAACAGCTATCGAGCTGCACATCTGTTGAACGTTTCCTCGCAGTACTGCTGCAATGTTTGCATGGCCATGTTTGGCACGCTGTCCCAACTGTACGAACATCGGTACAGCAACCATCACTACTTTCCACGCCGTAGAGGTCTGCTGGAAGTCCTATGCCCGGAATCAGATGAACTGTTATTAAATTGCGAATTGTGTGGTTTCTGTTGCAATCAGCTCCGTACGCTGCTACAGCACCGAGCTGAGAAACACGCCAATACTGACCACGATAACACACCGTTGGCGGAGAAACTAGCCGCTCCACAAAAGACGACTAAAAAGCTTGACAAGGAAGAGACGACCcggcagttcctgtgcgaaaagtgtggcaaaacgtacacccagtccagtcatctttggcagcatctgcgcttccacaacaaggtacggccgttctcatgctccgttcagggttgcaaccgaagtttcacgatacggcccgatcttagcgaccacatccggaagtgccacaccggcgaacggccgtacgcgtgtgaggtgtgtcataagcgcttcctgaccggttctgtgttttatcagcaccgattgatccatcgaaacgagcggcgtcatgcttgttcgaaatgtgatcgcaggttttaccgggcggatgcactgaagaaccacatgcgaattcataccggcgaaaaaccgtacgcatgtacgcattgtaatcgcaagtttcggcagcgtggcgatcgggagaagcatgtgCGCGTAAAGCACATGAAGTTTTGTTAA
- Protein Sequence
- MGRIKKIEVSQVTQTLGKNTQQWQNVLQQSGPSKSKAKAANRKKFNCQHCKRKFVYLTGLARHEKKFHPEKEKSSNPGTEQTEKEAATGAVSNTPPTTTFEIVVKCKNCGEIFPDAERFEAHTSRLSWEQLFGNQPEEQDEKVSLFLAQLFIVVIHMALQCEFCDAHFSDFASLFYHESHHSPYAGYSCTFCKLNFLTLEAVLDHREQCQEYNSYRAAHLLNVSSQYCCNVCMAMFGTLSQLYEHRYSNHHYFPRRRGLLEVLCPESDELLLNCELCGFCCNQLRTLLQHRAEKHANTDHDNTPLAEKLAAPQKTTKKLDKEETTRQFLCEKCGKTYTQSSHLWQHLRFHNKVRPFSCSVQGCNRSFTIRPDLSDHIRKCHTGERPYACEVCHKRFLTGSVFYQHRLIHRNERRHACSKCDRRFYRADALKNHMRIHTGEKPYACTHCNRKFRQRGDREKHVRVKHMKFC
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -