Amac001371.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles maculipalpis
Gene Symbol
-
Assembly
GCA_943734865.1
Location
CALSEK010000022.1:413242-419912[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 1.3 70 4.0 3.6 1 23 247 270 247 270 0.90
2 11 2.8 1.5e+02 3.0 3.2 1 23 276 299 276 299 0.90
3 11 2.7e-05 0.0015 18.7 1.7 1 23 322 344 322 344 0.98
4 11 0.00015 0.0079 16.4 0.5 1 23 351 373 351 373 0.98
5 11 0.0039 0.21 12.0 0.2 1 23 391 414 391 414 0.96
6 11 0.0047 0.25 11.7 0.9 1 23 433 455 430 455 0.92
7 11 0.0003 0.016 15.5 0.1 1 23 581 604 581 604 0.96
8 11 0.00029 0.016 15.5 7.0 1 23 713 736 713 736 0.98
9 11 0.0026 0.14 12.5 1.7 3 23 744 764 742 764 0.97
10 11 0.028 1.5 9.3 1.1 1 23 779 801 779 801 0.99
11 11 2.8e-05 0.0015 18.7 0.0 2 23 818 840 817 840 0.95

Sequence Information

Coding Sequence
ATGGAGGAACCGCGGGATGCGAGATGCGAAACGAAAACTTCTCATCCAACGCAACCATCGGTCGAACCAGGGCAACAACGCACAATTTCCAGCGGTAAGATGGTAGTAATCTGCAGAATTTGTCTTACCACCCGTCCACGGATGATATCGATCCACAGTCCAGTCCCCGAGTACGATCAGAAAACATTGTACGCGATGCTACTGTCCGTCTGTCTGCCACTCAACCAACGCGAAACGATACAGGGCTTTCCGGAACAAATTTGCCGCAACTGCCAGTGGAAGCTGCTATCGGCGTACGATCTGTACGAGACAACCCTTGCCAGTGATGAGCAATTGCGAGCACAAACGCATCTCACATTGACAGCAAAGATCACAAAGAATACGCCGTCTAGCGAACCAGTCAAACAGGATAGCAGTGTACCGGTGCCAGCGAACGTGCCCAGCGATGGTCTTATCCGGGTGAAGGAAGAAACGCCCGACGATGGATACGAGGATGAACAACAGTACGGACCAGGCAGTAGAATTGGAGAAGATTGCAGCATGGCTTACGACGCTGCGACCGGTGAGATGAGTACGGTTAGTGTTCATCCTGACGTGTCCTTGCTAATCGGACGCAGTGAGCAGGGCGAGGACGAGGAGGACACTAGCTTGCTGCTAGAGGAAACGAAACCACCGATTCTGGACCCGCTCGAAACGTTCATCGCAGAACATTACCAGGTGAATGAGCTTACCGGTGGTCACGTGTGTGGTCTGTGCAAGCGCGACTTCCCGTACAAGAGCCAGTGCCGGATGCACATCGTCCAGAAGCACAATCCGGCCAAACCGTTCAAGTGTGATATTTGTTTCTGCACACTCACCAGCCATCTGCGCTTGGTCCGGCACAAGGTAGTTGCACACGGTGCCGGTCAGATCAAGCGCGAAGACATCATAGAGGGACACAACGACACAACCGGCGAGCTAACGTATACCTGTCCGATCTGTCGAAAGGTGTTTAATTCGTCGGTACGCTTCAAGCGCCACAAAAATGTGCACGTCGTGCACAATCGACCGTTCAAGTGCGAGGTATGCCTGTACCGGTTTGCCACGAAGCCACAGCTGACGCAGCACGCCAAAGTGCACGAAACGAAGCCACCGTCTGGTCTGTCGCCGGGCGGTTCCGAGGTGGGTGAGTTTGCTTGCGATCGCTGTGAGGAAATTTTTACCGCTAAGCGTGCCCTCACGATGCACCTGAAGAAGGTGCACCAAGTGTTCCGTGTGCCGGGCAGTGGTCGGCCAGAAGAACGCGAACGCTGTGAGTACGTGTGTATCATCTGCAAGGCAACGTTTGCGCGCGAAACTGTCCTTAACACGCACATGAAGATGCACGAACTGTTGGCGGCAGAAAAGGAAAAGGAACGGCGGCTCGATCTTGAACGTATGGTTAAGCAGGAACTGCAGCAACAGATGCACCTAAGTGTGCCACCCTTACCGCCACTATCGCCGGAAGTGATTGATCGTTCCGCTTGCGTACTGGAACCGTTCGCACTGGGGCTCGTTCCGGTAGCGAAACCGGGCATTACTGGTACGGGGACGAACAATAACGATAGTAGCAGCATTAACAACAACAGTCCACCGACGGGGGGTGGTGGTGCATCGACAGGTAGTGGTGGATCCGGAGGTCCAAGTGGTTCGGTGCAGGTTGGCAGTGGTAAGCGAAAGATACCTATGACACCAACCGGACCGGTCAGTAGTGATATGGCGTACGTATGTCCGGTGTGCGACATGGAGTTTGATGAACGGGATGTGCTGAAGAAACATCAGAAGGAGCAACACGCCCGGCTACAGGTTGGCATCGTGTCATCGAAGCTTAGTGAATCGATCAGTTCGAACAGTGGTTCCAGTCCGCAGGCGAAGCTAATGCCACGGTTTACCGATATGCCGAGTTTGAAAATGAGGCTGATGGATAGCTCTGTCCGGGGAGGCAAAAAGCGACTGCTGAGCGATGCAAACGCCATGAACTACATGGACGAACCATTAGACCATGATGAATCAACCGACACCGATGGCCTCATACCTATGGATGACATTCCCGCGAATGCTGAACGGCGGTCCACGACTGGTGCGACAGCATCATTACCCGGTGAGGAACCGTCTCAGTTCCAGTGCGAACTGTGCCATAAAAAGTTCCCGTACAACTGTTACTTAACGATGCACATGCGAAAGAACCACGACAAATCCAAACCGTACGGCTGTAAAGTATGCCATTACCGTTTCGGGTACCGTGGCACATTGTTGCGCCATCAGCTCTTACACTCCTCGCAGCGTGTCCAGCCAGGTAGCCACGGTTCGATCATCTTCAAGTGTCGCATCTGTTCGGCCAAATTTCTCGAGCTAAAGCAACTAAATGTGCATCTAAAAACGCATCGAAAGATGGCGATCGAGCAGGATACTAATCGGCAGGTGCAGTTGATACGCTGCGATGAGTGTCCGCAGATTTTTAGCGATCCCGATCAGCTAGCGGCGCACATGGTGAAGGAGCACCAGCAGCACCATAGTACCGATGATGAGCTATACGATTCGGACCGGTTGTTAGCGCAGCAGCAGCATTCCACACTGTTGATGAATCCTTCGTCTTCATCTTTACGAGGCGATCACAGCCGTACTGGTGCATCCATCCTTAACGATCTCAAATTAAATTCCGAACAGTCGACGGACGACACCAATGAAGCATTCATGAACGAGAGCGATATATCGCTGGTCAAGATAGAGCCAAATTATGATTGA
Protein Sequence
MEEPRDARCETKTSHPTQPSVEPGQQRTISSGKMVVICRICLTTRPRMISIHSPVPEYDQKTLYAMLLSVCLPLNQRETIQGFPEQICRNCQWKLLSAYDLYETTLASDEQLRAQTHLTLTAKITKNTPSSEPVKQDSSVPVPANVPSDGLIRVKEETPDDGYEDEQQYGPGSRIGEDCSMAYDAATGEMSTVSVHPDVSLLIGRSEQGEDEEDTSLLLEETKPPILDPLETFIAEHYQVNELTGGHVCGLCKRDFPYKSQCRMHIVQKHNPAKPFKCDICFCTLTSHLRLVRHKVVAHGAGQIKREDIIEGHNDTTGELTYTCPICRKVFNSSVRFKRHKNVHVVHNRPFKCEVCLYRFATKPQLTQHAKVHETKPPSGLSPGGSEVGEFACDRCEEIFTAKRALTMHLKKVHQVFRVPGSGRPEERERCEYVCIICKATFARETVLNTHMKMHELLAAEKEKERRLDLERMVKQELQQQMHLSVPPLPPLSPEVIDRSACVLEPFALGLVPVAKPGITGTGTNNNDSSSINNNSPPTGGGGASTGSGGSGGPSGSVQVGSGKRKIPMTPTGPVSSDMAYVCPVCDMEFDERDVLKKHQKEQHARLQVGIVSSKLSESISSNSGSSPQAKLMPRFTDMPSLKMRLMDSSVRGGKKRLLSDANAMNYMDEPLDHDESTDTDGLIPMDDIPANAERRSTTGATASLPGEEPSQFQCELCHKKFPYNCYLTMHMRKNHDKSKPYGCKVCHYRFGYRGTLLRHQLLHSSQRVQPGSHGSIIFKCRICSAKFLELKQLNVHLKTHRKMAIEQDTNRQVQLIRCDECPQIFSDPDQLAAHMVKEHQQHHSTDDELYDSDRLLAQQQHSTLLMNPSSSSLRGDHSRTGASILNDLKLNSEQSTDDTNEAFMNESDISLVKIEPNYD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00108600;
90% Identity
-
80% Identity
-