Amac007268.1
Basic Information
- Insect
- Anopheles maculipalpis
- Gene Symbol
- -
- Assembly
- GCA_943734865.1
- Location
- CALSEK010000114.1:895284-896825[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 8 0.00021 0.011 16.0 2.3 1 23 251 274 251 274 0.97 2 8 0.0048 0.26 11.7 3.3 1 23 280 303 280 303 0.95 3 8 2.6e-05 0.0014 18.8 0.5 1 23 309 331 309 331 0.98 4 8 1.2e-05 0.00065 19.9 4.0 1 23 336 358 336 358 0.98 5 8 0.00071 0.038 14.3 1.0 3 23 366 386 365 386 0.98 6 8 0.0009 0.048 14.0 0.2 2 23 393 414 392 414 0.93 7 8 1e-05 0.00054 20.1 2.8 1 23 420 443 420 443 0.98 8 8 9.3e-06 0.0005 20.2 1.4 1 23 449 472 449 472 0.98
Sequence Information
- Coding Sequence
- ATGAGCATCTGTCGTACCTGTCTGCAAAAGGAAGCTGAAGCATATTGTTCGTTATTTAAAACAATTCACCATGTTACACTCCAAGAAATGTACCATTCGCTGACCGGCTTGAGTGTCTCGCGGGAAGATGGTTTGCCGGACTATGTATGCCAAGAGTGTGCCGATTTCCTCGTTACCTGTAACAATTTTCGCAAAAAATGTATCAAATCAGATGCTCAACTAAGGAACGATCTTGCCAAGGGTAGCGGCGAAACTGAGCTTGTTCGAGTTGAAGAATTTGAGTGTCTCGAAGTGGATTCAAATGAACCGACACAAATTAAGATATATTTCGACGAAAGCCATTACATCCTTCCGGATAAAATAGACGGCCAGGAAGAAATCGTCCCGAATGAACAAAAGCTTACCTTTCATATAGAAGACGATAGCAGTGTAAGGACGAACGATGACGAGTCTGGTTACTCAGTTTACGACGTAACGGAGGAAGAAGAATTGGTCGAGATAACACCAGACGCTGAAAGCGAAAATGGGCAATCGTATGAGTTTTTCCTCGATTCAGAGGAAATTCTCGAAAAGCCTCAAACGTCGTCTGTAGACGAAACAGAGAAACCAACATCGACGGATAATGCGACGACACCGTCCACTGTACGCTGTTGCGCCTGCCCAGCGTTACAATTCGATACGATCGAAGGTTTAAAGCTACACTCACTCGCTGTGCACGCGAAGAACCGCACCGAAAACAAGTTACGGCTTTACGAGTGCGACATTTGCTACCGACGCTACACCCAAAATGATCATTTTCTAAATCATAAAGCAACAATACATCTGCCAAAGAAAGTGTACGACTGCAAATCGTGTGATGCCAGCTTCAAAAGTCGGACGGCTTTGCACAGCCACAACAAAAGCAAACACGTGTGCGAGAGAACGTACGTTTGTGAGATTTGCCAGAAAGGATTCTACACCAGTAATACGCTGCTGTCCCATCGGCTAATACACGGCGAGAAAAAATTTCGGTGCGACAAGTGTTCGAAAATGTTCGCACGCCATTGGGATCTGAGAACCCATCAAAAGTCACATTCTAACGAACGGCCGCACGGTTGCAGTGTATGCAAGATGCGCTTCAAAACGCTTGCCCACCTGCGAGGCCATCAAGCGGTACACACCGGGGAACGGTCGATAAAGTGTCGCATATGTGGGAAAGGATTCACCACGTACGGCGATCGACGAGTGCATGAGCTAGAGCATGAAAATATTCATCCGTTTAAGTGCACCTTTTGTGACAAACGGTACGGTCGAAACTATAAGCTACAGGCGCACATTAAGAAAATGCACACTGGCGAGCGACCATTTGTGTGCTGCGATTGTTCGCAAAGTTTCATCCAACGGTGGGAATTGACGGCTCATCGGAGAACGGTACATGGCGAGGGAGAAGGTTTGTCGATGGACGTGATAGTAGAGGGATGA
- Protein Sequence
- MSICRTCLQKEAEAYCSLFKTIHHVTLQEMYHSLTGLSVSREDGLPDYVCQECADFLVTCNNFRKKCIKSDAQLRNDLAKGSGETELVRVEEFECLEVDSNEPTQIKIYFDESHYILPDKIDGQEEIVPNEQKLTFHIEDDSSVRTNDDESGYSVYDVTEEEELVEITPDAESENGQSYEFFLDSEEILEKPQTSSVDETEKPTSTDNATTPSTVRCCACPALQFDTIEGLKLHSLAVHAKNRTENKLRLYECDICYRRYTQNDHFLNHKATIHLPKKVYDCKSCDASFKSRTALHSHNKSKHVCERTYVCEICQKGFYTSNTLLSHRLIHGEKKFRCDKCSKMFARHWDLRTHQKSHSNERPHGCSVCKMRFKTLAHLRGHQAVHTGERSIKCRICGKGFTTYGDRRVHELEHENIHPFKCTFCDKRYGRNYKLQAHIKKMHTGERPFVCCDCSQSFIQRWELTAHRRTVHGEGEGLSMDVIVEG
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -